• Title/Summary/Keyword: 4D Planning

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Dosimetric Comparison of Three Dimensional Conformal Radiation Radiotherapy and Helical Tomotherapy Partial Breast Cancer (유방암 환자의 3D-CRT, TOMO 방법에 따른 선량 분포 평가)

  • Kim, Dae-Woong;Kim, Jong-Won;Choi, Yun-Kyeong;Kim, Jung-Soo;Hwang, Jae-Woong;Jeong, Kyeong-Sik;Choi, Gye-Suk
    • The Journal of Korean Society for Radiation Therapy
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    • v.20 no.1
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    • pp.11-15
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    • 2008
  • Purpose: The goal of radiation treatment is to deliver a prescribed radiation dose to the target volume accurately while minimizing dose to normal tissues. In this paper, we comparing the dose distribution between three dimensional conformal radiation radiotherapy (3D-CRT) and helical tomotherapy (TOMO) plan for partial breast cancer. Materials and Methods: Twenty patients were included in the study, and plans for two techniques were developed for each patient (left breast:10 patients, right breast:10 patients). For each patient 3D-CRT planning was using pinnacle planning system, inverse plan was made using Tomotherapy Hi-Art system and using the same targets and optimization goals. We comparing the Homogeneity index (HI), Conformity index (CI) and sparing of the organs at risk for dose-volume histogram. Results: Whereas the HI, CI of TOMO was significantly better than the other, 3D-CRT was observed to have significantly poorer HI, CI. The percentage ipsilateral non-PTV breast volume that was delivered 50% of the prescribed dose was 3D-CRT (mean: 40.4%), TOMO (mean: 18.3%). The average ipsilateral lung volume percentage receiving 20% of the PD was 3D-CRT (mean: 4.8%), TOMO (mean: 14.2), concerning the average heart volume receiving 20% and 10% of the PD during treatment of left breast cancer 3D-CRT (mean: 1.6%, 3.0%), TOMO (mean: 9.7%, 26.3%) Conclusion: In summary, 3D-CRT and TOMO techniques were found to have acceptable PTV coverage in our study. However, in TOMO, high conformity to the PTV and effective breast tissue sparing was achieved at the expense of considerable dose exposure to the lung and heart.

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A Study of Automated Process Planning and Die Design for Multi Former-Bolt Products (다단포머-볼트류 공정 및 금형설계 자동화 시스템 개발)

  • Park, Chul-Woo;Kang, Jung-Hoon;Lee, Jun-Ho;Kim, Chul;Kim, Moon-Saeng;Choi, Jae-Chan
    • Journal of the Korean Society for Precision Engineering
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    • v.20 no.4
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    • pp.29-38
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    • 2003
  • This paper deals with an automated computer-aided process planning and die design system with which designer can determine operation sequences even after only a little experience in process planning and die design of multi former-bolt products by multi-stage former working. The approach is based on knowledge-based rules, and a process knowledge base consisting of design rules is built. Knowledge fur the system is formulated from plasticity theories, empirical results and the empirical knowledge of field experts. Programs for the system have been written in AutoLISP for AutoCAD with a personal computer. An attempt is made to link programs incorporating a number of expert design rules with the process variables obtained by commercial FEM softwares, DEFORM and ANSYS, to form a useful package. The system is composed of four main modules. The process planning and die design module considers several factors, such as the complexities of preform geometry, punch and die profiles, specifications of available multi former, and the availability of standard parts. It can provide a flexible process based on either the reduction in the number of forming sequences by combining the possible two processes in sequence, or the reduction of deviation of the distribution and the level of the required forming loads by controlling the forming ratios. The system uses 2D geometry recognition and is integrated with the technology of process planning, die design, and CAE analysis. The standardization of die parts for multi former-bolt products requiring a cold forging process is described. The system developed makes it possible to design and manufacture multi former-bolt products more efficiently.

Usefulness of Abdominal Compressor Using Stereotactic Body Radiotherapy with Hepatocellular Carcinoma Patients (토모테라피를 이용한 간암환자의 정위적 방사선치료시 복부압박장치의 유용성 평가)

  • Woo, Joong-Yeol;Kim, Joo-Ho;Kim, Joon-Won;Baek, Jong-Geal;Park, Kwang-Soon;Lee, Jong-Min;Son, Dong-Min;Lee, Sang-Kyoo;Jeon, Byeong-Chul;Cho, Jeong-Hee
    • The Journal of Korean Society for Radiation Therapy
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    • v.24 no.2
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    • pp.157-165
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    • 2012
  • Purpose: We evaluated usefulness of abdominal compressor for stereotactic body radiotherapy (SBRT) with unresectable hepatocellular carcinoma (HCC) patients and hepato-biliary cancer and metastatic liver cancer patients. Materials and Methods: From November 2011 to March 2012, we selected HCC patients who gained reduction of diaphragm movement >1 cm through abdominal compressor (diaphragm control, elekta, sweden) for HT (Hi-Art Tomotherapy, USA). We got planning computed tomography (CT) images and 4 dimensional (4D) images through 4D CT (somatom sensation, siemens, germany). The gross tumor volume (GTV) included a gross tumor and margins considering tumor movement. The planning target volume (PTV) included a 5 to 7 mm safety margin around GTV. We classified patients into two groups according to distance between tumor and organs at risk (OAR, stomach, duodenum, bowel). Patients with the distance more than 1 cm are classified as the 1st group and they received SBRT of 4 or 5 fractions. Patients with the distance less than 1 cm are classified as the 2nd group and they received tomotherapy of 20 fractions. Megavoltage computed tomography (MVCT) were performed 4 or 10 fractions. When we verify a MVCT fusion considering priority to liver than bone-technique. We sent MVCT images to Mim_vista (Mimsoftware, ver .5.4. USA) and we re-delineated stomach, duodenum and bowel to bowel_organ and delineated liver. First, we analyzed MVCT images to check the setup variation. Second we compared dose difference between tumor and OAR based on adaptive dose through adaptive planning station and Mim_vista. Results: Average setup variation from MVCT was $-0.66{\pm}1.53$ mm (left-right) $0.39{\pm}4.17$ mm (superior-inferior), $0.71{\pm}1.74$ mm (anterior-posterior), $-0.18{\pm}0.30$ degrees (roll). 1st group ($d{\geq}1$) and 2nd group (d<1) were similar to setup variation. 1st group ($d{\geq}1$) of $V_{diff3%}$ (volume of 3% difference of dose) of GTV through adaptive planing station was $0.78{\pm}0.05%$, PTV was $9.97{\pm}3.62%$, $V_{diff5%}$ was GTV 0.0%, PTV was $2.9{\pm}0.95%$, maximum dose difference rate of bowel_organ was $-6.85{\pm}1.11%$. 2nd Group (d<1) GTV of $V_{diff3%}$ was $1.62{\pm}0.55%$, PTV was $8.61{\pm}2.01%$, $V_{diff5%}$ of GTV was 0.0%, PTV was $5.33{\pm}2.32%$, maximum dose difference rate of bowel_organ was $28.33{\pm}24.41%$. Conclusion: Despite we saw diaphragm movement more than 5 mm with flouroscopy after use an abdominal compressor, average setup_variation from MVCT was less than 5 mm. Therefore, we could estimate the range of setup_error within a 5 mm. Target's dose difference rate of 1st group ($d{\geq}1$) and 2nd group (d<1) were similar, while 1st group ($d{\geq}1$) and 2nd group (d<1)'s bowel_organ's maximum dose difference rate's maximum difference was more than 35%, 1st group ($d{\geq}1$)'s bowel_organ's maximum dose difference rate was smaller than 2nd group (d<1). When applicating SBRT to HCC, abdominal compressor is useful to control diaphragm movement in selected patients with more than 1 cm bowel_organ distance.

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Optimizing Urban Construction and Demolition Waste Management System Based on 4D-GIS and Internet Plus

  • Wang, Huiyue;Zhang, Tingning;Duan, Huabo;Zheng, Lina;Wang, Xiaohua;Wang, Jiayuan
    • International conference on construction engineering and project management
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    • 2017.10a
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    • pp.321-327
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    • 2017
  • China is experiencing the urbanization at an unprecedented speed and scale in human history. The continuing growth of China's big cities, both in city land and population, has already led to great challenges in China's urban planning and construction activities, such as the continuous increase of construction and demolition (C&D) waste. Therefore, how to characterize cities' construction activities, particularly dynamically quantify the flows of building materials and construction debris, has become a pressing problem to alleviate the current shortage of resources and realize urban sustainable development. Accordingly, this study is designed to employ 4D-GIS (four dimensions-Geographic Information System) and Internet Plus to offer new approach for accurate but dynamic C&D waste management. The present study established a spatio-temporal pattern and material metabolism evolution model to characterize the geo-distribution of C&D waste by combing material flow analysis (MFA) and 4D-GIS. In addition, this study developed a mobile application (APP) for C&D waste trading and information management, which could be more effective for stakeholders to obtain useful information. Moreover, a cloud database was built in the APP to disclose the flows of C&D waste by the monitoring information from vehicles at regional level. To summarize, these findings could provide basic data and management methods for the supply and reverse supply of building materials. Meanwhile, the methodologies are practical to C&D waste management and beyond.

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A Study on the Visual Preference in Enclosed Spaces Based on the Paired Comparison Method (쌍체비교기법을 통한 중정의 시각적 선호에 관한 연구)

  • 이태희;임승빈
    • Journal of the Korean Institute of Landscape Architecture
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    • v.14 no.3
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    • pp.3-19
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    • 1987
  • The purpose of this study was to investigate desirable width / height ratio of enclosed space and to offer basic information for the design of enclosed spaces. The data of this study were gathered from the experiment through simulation. Photographic sampling of 7 campus sites located in Kwanak campus of Seoul National University and slides of perspective drawings of enclosed spaces with various D/H ratio (12, 1, 2, 4, 6, 9, 12)were used for simulation. A response format was made using the method of paired comparison and students from various departments were randomly selected for evaluation. In the method of analysis of data Thurstone's equation of Comparative Judgement was used for calculating preference score. A1so non-linear regression analysis was used for finding out relations between preference and D/H ratio. The other method of data analysis were correlation, Chi - test. And the results were summarized as follows. 1. In sketch simulation the ratio of D/H 4 got the highest preference store. This result suggests that desirable D/H ratio of enclosed space is D/H 4. And at the lower range of D/H ratio, as ratio increases, the preference score increases. At the higher range of D/H ratio, however, as ratio increases, the preference score starts to decrease from the cardinal point of D/H 4. 2. In campus photograph simulation preference is influenced by slope, elevation change of floor, trees, lawn area, familiarity, space arrangement, and exterior shape of building besides D/H ratio. 3. The preference virtue was not significantly affected by order effect. This result suggests that order effect can be ignored in the study of visual preference. 4. There are so many factors related to preference that it is difficult to explore those factors without scientific information based on scientific method. We must carry out study for scientific approach of planning and design based on precise, complete simulation technique.

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Theoretical Consideration of the Components of Preservice Mathematics Teacher Training

  • Lee, Joong-Kwoen
    • Research in Mathematical Education
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    • v.4 no.1
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    • pp.23-31
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    • 2000
  • This research elaborated five components for pre-service mathematics teacher training: 1) Mathematical content knowledge, 2) Pedagogical content knowledge, 3) Pedagogical reasoning, 4) System of training, and 5) Mathematics teachers' beliefs. For the effect teaching, mathematics teacher program should be reformed. The key to improvement should be concerntrated on developing knowledge about effective teaching and translating it into algorithms those teachses can learn and incorporate in their planning prior to teaching. A theory of instruction should specify the most effective sequences in which to present the materials to be learned.

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Process Optimization of Biphenile Chloromethylation

  • Pak, V.V.;Karimov, R.K.;Shakhidoyatov, Kh.M.;Soh, D.W.
    • Journal of the Speleological Society of Korea
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    • no.73
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    • pp.1-8
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    • 2006
  • Optimization of the biphenile chloromethylation process with paraphormaldegide has been done in the presence of $ZnCl_2$ with HCl gas by the Box-Wilson method of mathematical planning of experiment. The 4,4'-(dichloromethyl)-biphenile yield dependence on the piphenile -paraphormaldegide ratio, temperature and reaction duration has been studied. A mathematical model of the process has been developed and optimal conditions for the biphenile chloromethylation procedure has been determined.

Extension of Self-organization for Swarm Systems to Three Dimensions (스웜시스템을 위한 자기조직화의 3D 확장)

  • Kim, Jae-Hyun;Kim, Dong-Hun
    • Journal of the Korean Institute of Intelligent Systems
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    • v.20 no.4
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    • pp.489-496
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    • 2010
  • In this paper, a self-organization framework for swarm systems in three dimensions is presented. The framework uses artificial potential functions(APFs) to direct the robots toward the goal as well as to keep them in a swarm system. This research extends conventional APFs used for self-organizations in two dimension environment to three dimensions. In three dimension environment, the ground potential for the boundary surfaces that commonly appear in three dimension environments is proposed. Accordingly, the comparison between the paths without and with the ground potentials shows the necessity and effect of ground potentials. Extensive simulations are given to show the effectiveness of the extended potentials and various properties in three dimension environments.

A phantom production by using 3-dimentional printer and In-vivo dosimetry for a prostate cancer patient (3D 프린팅 기법을 통한 전립샘암 환자의 내부장기 팬텀 제작 및 생체내선량측정(In-vivo dosimetry)에 대한 고찰)

  • Seo, Jung Nam;Na, Jong Eok;Bae, Sun Myung;Jung, Dong Min;Yoon, In Ha;Bae, Jae Bum;Kwack, Jung Won;Baek, Geum Mun
    • The Journal of Korean Society for Radiation Therapy
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    • v.27 no.1
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    • pp.53-60
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    • 2015
  • Purpose : The purpose of this study is to evaluate the usefulness of a 3D printed phantom for in-vivo dosimetry of a prostate cancer patient. Materials and Methods : The phantom is produced to equally describe prostate and rectum based on a 3D volume contour of an actual prostate cancer patient who is treated in Asan Medical Center by using a 3D printer (3D EDISON+, Lokit, Korea). CT(Computed tomography) images of phantom are aquired by computed tomography (Lightspeed CT, GE, USA). By using treatment planning system (Eclipse version 10.0, Varian, USA), treatment planning is established after volume of a prostate cancer patient is compared with volume of the phantom. MOSFET(Metal OXIDE Silicon Field Effect Transistor) is estimated to identify precision and is located in 4 measuring points (bladder, prostate, rectal anterior wall and rectal posterior wall) to analyzed treatment planning and measured value. Results : Prostate volume and rectum volume of prostate cancer patient represent 30.61 cc and 51.19 cc respectively. In case of a phantom, prostate volume and rectum volume represent 31.12 cc and 53.52 cc respectively. A variation of volume between a prostate cancer patient and a phantom is less than 3%. Precision of MOSFET represents less than 3%. It indicates linearity and correlation coefficient indicates from 0.99 ~ 1.00 depending on dose variation. Each accuracy of bladder, prostate, rectal anterior wall and rectal posterior wall represent 1.4%, 2.6%, 3.7% and 1.5% respectively. In- vivo dosimetry represents entirely less than 5% considering precision of MOSFET. Conclusion : By using a 3D printer, possibility of phantom production based on prostate is verified precision within 3%. effectiveness of In-vivo dosimetry is confirmed from a phantom which is produced by a 3D printer. In-vivo dosimetry is evaluated entirely less than 5% considering precision of MOSFET. Therefore, This study is confirmed the usefulness of a 3D printed phantom for in-vivo dosimetry of a prostate cancer patient. It is necessary to additional phantom production by a 3D printer and In-vivo dosimetry for other organs of patient.

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ACCURACY TESTS OF 3D RAPID PROTOTYPING (RP) MEDICAL MODELS: ITS POTENTIAL AND CLINICAL APPLICATIONS (Rapid Prototyping으로 제작한 3D Medical Model의 오차 측정에 관한 연구 (임상 적용 가능성 및 사례))

  • Choi, Jin-Young;Choi, Jung-Ho;Kim, Nam-Kuk;Lee, Jong-Ki;Kim, Myeng-Ki;Kim, Myung-Jin;Kim, Yeong-Ho
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.25 no.4
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    • pp.295-303
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    • 1999
  • Presented in this paper are the experimental results that measure rapid prototyping (RP) errors in 3D medical models. We identified various factors that can cause dimensional errors when producing RP models, specifically in maxillofacial areas. For the experiment, we used a human dry skull. A number of linear measurements based on landmarks were first obtained on the skull. This was followed by CT scanning, 3D model reconstruction, and RP model fabrication. The landmarks were measured again on both the reconstructed models and the physical RP models, and these were compared with those on dry skull. We focused on major sources of errors, such as CT scanning, conversion from CT data to STL models, and RP model fabrication. The results show that the overall error from skull to RP is $0.64{\times}0.36mm(0.71{\times}0.66%)$ in absolute value. This indicates that the RP technology can be acceptable in the real clinical applications. A clinical case that has applied RP models successfully for treatment planning and surgical rehearsal is presented. Although the use of RP models is rare in the medical area yet, we believe RP is promising in that it has a great potential in developing new tools which can aid diagnosis, treatment planning, surgical rehearsal, education, and so on.

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