• Advances in pediatric surgery
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• v.15 no.2
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• pp.113-120
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• 2009

Pediatric lymphangioma can occur at any site. However the neck is the most common site. There are two treatment modalities (surgical excision and intralesional injection) for lymphangiomas. But, the treatment guide line for lymphangioma has not been established, yet. The aim of this study is to establish the treatment guide line based on our experience with lymphangiomas. Medical records of 82 cases of lymphangioma were reviewed retrospectively. On MRI (magnetic resonance image) findings, lymphangiomas were divided into 4 groups by the proportion of the cyst bigger than 2 cm in diameter of the tumor; group A-proportion of cyst occupies more than 75%, group B-proportion of the cyst 50~75%, group C-25~50%, and D in less than 25%. All patients were treated with OK-432 intralesional injection as the initial treatment. The effective response rates of OK-432 in group A & B were 88.2% and 88.8%, respectively. Group C response was 38.0% and D only 20.0%. Twenty-three patients received surgical excision. The result of surgical excision was generally satisfactory. Surgical site infection occurred in 1 case and postoperative bleeding in 1 case. Theses results indicate that intralesional injection of OK-432 could be the first line therapy in group A & B. In group C, OK-432 would be better as the first line therapy than surgery. For the group D, surgical excision should be the first line of treatment.

• Korean Journal of Biological Psychiatry
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• v.7 no.1
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• pp.14-20
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• 2000

Recently atypical antipsychotics have been used as first line agent in the treatment of schizophrenia, and also played a significant role in the treatment of many kinds of psychiatric disorders. The pharmacokinetic and pharmacodynamic properties of these newer antipsychotics are well known through preclinical and early clinical trials. However, it is important to note the limitations of the results due to its relatively short experience. Clozapine is eliminated principally by the hepatic P450 1A2 and 3A4 cytochrome enzymes. 1A2 inducers such as carbamazepine and smoking can reduce its half-life, while 1A2 inhibitors such as SSRIs, especially fluvoxamine can increase its duration of action. Carbamazepine should be avoided in a patient on clozapine because of carbamazepine's potential effects on bone marrow. Benzodiazepines tend to increase the chances of sedation, delirium and respiratory depression. Risperidone is metabolized to 9-hydroxyriperidone by the hepatic P450 2D6 cytochrome enzymes. Fluoxetine and paroxetine, 2D6 inhibitors interfere with metabolism, but 9-hydroxyrisperidone has similar biological activity as parental drug, so it has little affect on the outcome. Olanzapine shows minimal capacity to inhibit cytochrome P450 isoenzymes and shows minimal chance of drug interaction. It is eliminated principally by the hepatic P450 1A2 and 2D6 cytochrome enzymes.

• Annals of Hepato-Biliary-Pancreatic Surgery
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• v.26 no.3
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• pp.285-288
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• 2022

Three-dimensional (3D) modeling of the liver can be especially useful for both the surgeon and patient to understand the actual location of the tumor and planning the resection plane. Virtual reality (VR) can enhance the understanding of 3D structures and create an environment where the user can focus on contents provided. In the present study, a VR platform was developed using Unreal Engine 4 software (Epic Games, Potomac, MD, USA). Patient's liver based on magnetic resonance image was imported as a 3D model that could distinguish liver parenchyma, vascular structure, and cancer. Preoperative education videos for patients were developed. They could be viewed inside the VR platform. To evaluate the usefulness of VR education program for patients undergoing liver resection for hepatocellular carcinoma, a randomized clinical trial evaluating the knowledge and anxiety of the patient was designed. The case presented in this report was the first experience of performing the VR education program and examining the knowledge and anxiety using questionnaires. When the knowledge score increased, the anxiety score also increased after the education program. Based on findings of this pilot case study, the timing and place where the questionnaire will be answered can be modified for formal initiation of the randomized controlled study to examine the usefulness of VR in patient education.

• Asia-Pacific Journal of Business Venturing and Entrepreneurship
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• v.7 no.4
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• pp.159-168
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• 2012

The purpose of this study is to analyze the relationship of MOT and NPD performance in medium-sized manufacturing firms. To accomplish the purpose of the study, working hypotheses were established based on the literatures about the impacts of MOT factors on the NPD performance. The sample of this study is as follows : 12 electrical and electronics companies, 18 machine and engineering companies, 16 parts and materials companies. In order to verify hypotheses, the data were collected from team leader and manager of research center, R&D, and production department of these companies and the leader of R&D project team who all had experience in project or were participating in it in latest 3 years. The results of study were summarized as follows : First, in analysis on the reality of MOT factors in sample firms, will of top management level on the MOT was comparatively high but relatedness of business strategy and technology strategy, open R&D system, systematic time scheduling, management of R&D manpower, and developing and adapting PLM system were common level. Second, to improve NPD performance in medium-sized manufacturing firms, will of top management level on the MOT, relatedness of business strategy and technology strategy, open R&D system, systematic time scheduling, management of R&D manpower, and developing and adapting PLM system were intensively required.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.15 no.4
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• pp.2225-2234
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• 2014

The objective of this study was to the effects of emotional labor and nursing organizational culture on the self-efficacy among clinical nurses. The subjects of this study were the clinical nurses working at 6 general hospitals in C & D city. The self-reported questionnaires were administered to 475 clinical nurses. The levels of self-efficacy, nursing organizational culture and emotional labor of the subjects were revealed moderate to high. Self-efficacy and emotional labor, emotional labor and nursing organizational culture showed a negative correlation, Self-efficacy and nursing organizational culture showed a positive correlation. Nursing organizational culture affects the self-efficacy that is significant explanatory variables, of which variables are in general education, job satisfaction, and employee turnover experience. The findings suggested that Nurses' self-efficacy for managing environmental management programs with interventions seem to be necessary.

• Journal of the Korean Association of Geographic Information Studies
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• v.13 no.4
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• pp.170-180
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• 2010

With development of the earth's subsurface space, the need for a reliable subsurface spatial model such as a cross-section, boring log is increasing. However, the ground mass was essentially uncertain. To generate model was uncertain because of the shortage of data and the absence of geotechnical interpretation standard(non-statistical uncertainty) as well as field environment variables(statistical uncertainty). Therefore, the current interpretation of the data and the generation of the model were accomplished by a highly trained experts. In this study, a geotechnical ontology model was developed using the current expert experience and knowledge, and the information content was calculated in the ontology hierarchy. After the relative distance between the information contents in the ontology model was combined with the distance between cluster centers, a cluster analysis that considered the geotechnical semantics was performed. In a comparative test of the proposed method, k-means method, and expert's interpretation, the proposed method is most similar to expert's interpretation, and can be 3D-GIS visualization through easily handling massive data. We expect that the proposed method is able to generate the more reasonable subsurface spatial information model without geotechnical experts' help.

• Journal of Broadcast Engineering
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• v.22 no.4
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• pp.473-483
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• 2017

Since the advent of 3D and UHD contents, demand for high-quality panoramic images has been increasing. The UWV(Ultra-Wide Viewing) service uses a wider viewing angle than conventional panoramas to provide a lively experience for users and enhance their understanding of the event. In this paper, we propose a spatial adjacency map generation method and an UWV file storage format technology to provide UWV service. The spatial adjacency map measures the similarity between images and generate the position information of the images based on similarity. And the stitching time of the image can be shortened through the generated position information. Through the spatial adjacency map, we generate the large screen content quickly. The UWV file format which is based on ISOBMFF process spatial adjacency map and videos and support random access. In this paper, we design the UWV player to verify the spatial adjacency map and UWV file format and show the result of experiments.

• Journal of Gastric Cancer
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• v.13 no.4
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• pp.266-272
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• 2013

We report our experience with two cases of situs inversus totalis, both involving patients diagnosed with gastric cancer. These were a 52-year-old male with a preoperative staging of cT1bN0M0 and a 68-year-old male with a staging of cT2N0M0, both of whom underwent surgery. The former was found to have vascular anomalies in the preoperative computed tomography, so we performed a computed tomography angiography with three-dimensional reconstruction. Laparoscopy-assisted distal gastrectomy with Billroth I anastomosis was performed with D1+ lymph node dissection, and a small laparotomy was made for extracorporeal anastomosis. In contrast, the latter case showed no vascular anomalies in the preoperative computed tomography, and totally laparoscopic distal gastrectomy with delta anastomosis was performed with D1+ lymph node dissection. There were no intraoperative problems in either patient and they were discharged without postoperative complications. Histopathological examination revealed a poorly differentiated adenocarcinoma (pT2N0M0) and a well-differentiated adenocarcinoma (pT1aN0M0), respectively.

• Transactions of the Korean Society for Noise and Vibration Engineering
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• v.24 no.4
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• pp.282-288
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• 2014

Three-dimensional multimedia industry such as 3D TV, movie and broadcast has been developed vividly. For generating 3D contents with high quality, virtual auditory display, so called VAD, is being researched to offer more realistic experience to listeners. When people render VAD using headphones or two speakers, head-related transfer function(HRTF) plays a key role. The best solution is measuring all individuals' HRTFs, but it is hard to measure all listeners' HRTFs. To overcome this difficulty, many research groups have tried to construct their own measurement system and to build HRTF databases. However, some of them have not enough subjects or spatial resolution and they are mainly focused on Caucasian. There exists difference between Korean and Caucasian in a view of physical features. In other words, if Koreans hear three-dimensional sound rendered by HRTF database based on Caucasian, performance might be hindered. To verify this possibility and remedy the drawbacks, construction of new HRTF database aimed at Korean is needed. Therefore, our laboratory built HRTF measurement system which can measure HRTF of three-dimensional space with dense spatial resolution. With this system, 55 Korean males and 45 females' HRTFs were measured and Korean HRTF database was built based on these data.

• Journal of the Computational Structural Engineering Institute of Korea
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• v.26 no.4
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• pp.241-246
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• 2013

From the numerical results of density-based topology design optimization, a CAD geometric model is constructed and fabricated using 3D printer to experimentally validate the optimal design. In the process of topology design optimization, we often experience checkerboard phenomenon and complicated branches, which could result in the manufacturing difficulty of the obtained optimal design. Sensitivity filtering and morphology methods are used to resolve the aforementioned issues. Identical volume fraction is used in both numerical and experimental models for precise validation. Through the experimental comparison of stiffness in various designs including the optimal design, it turns out that the optimal design has the highest stiffness and the experimental result of compliance matches very well with the numerical one.