• Clinical and Experimental Reproductive Medicine
• /
• v.23 no.1
• /
• pp.87-94
• /
• 1996

For evaluating the suitability of human follicular fluid(HFF) as protein supplement in ART, this preliminary study was performed to examine the maturation promoting activity of HFF on mouse follicular oocytes in vitro. Mouse follicular oocytes were collected from ovaries of 21-28 day old ICR mice by puncturing the antral follicles with fine needle at 48 hours after PMSG injection. The oocytes were rinsed and cultured in modified Whittingham's $T_6$ medium containing purines or dbcAMP to maintain meiotic arrest, and different concentrations of HFF were added into the culture medium to examine the effect of HFF on releasing the oocytes from the suppressive influence of the meiotic inhibitors. As a control for HFF, the maturation promoting activity of human fetal cord serum(HFCS) was investigated and compared with the activity of HFF. While HFF was separated, by molecular weight(M.W), into high M.W. fraction(M.W>30,000) and low M.W. fraction(M.W<30,000) and the effects of the fractions on meiotic resumption were investigated in the presence of the meiotic inhibitors. Also hormone analysis was performed to compare the content of hormones in HFF with that in HFCS. Same concentrations of HFF and HFCS induced similar germinal vesicle break down(GVBD) rates of the oocytes meiotic arrested by purines(4mM hypoxanthine+0.75mM adenosine), but the extrusion rate of 1st polar body(PB) of the oocytes cultured in HFF(65.0%, P<0.05) was significantly higher than that(51.6%) in HFCS. While, in the presence of 200 M dbcAMP, the maturation promoting activity of HFF (GVBD: 70.5%, $p<10^{-6}$; 1st PB extrusion: 67.1%, $p<10^{-3}$) was significantly greater than that of HFCS(GVBD: 35.2%; 1st PB extrusion: 41.1%). The oocytes cultured in the fraction of HFF containing high M.W. components showed higher meiotic maturation rates than the oocytes cultured in the low M.W. fraction of HFF. Gonadotropins and $E_2$ were known to improve the completion of maturation changes, and the levels of these hormones were higher in HFF than in HFCS. Therefore, HFF was more effective than HFCS to use for promoting meiotic resumption of mouse oocytes in vitro.

• Journal of the Institute of Electronics and Information Engineers
• /
• v.50 no.12
• /
• pp.40-48
• /
• 2013

This paper presents multi-channel transimpedance amplifier(TIA) arrays in short-range LADAR systems for unmanned vehicles, by using a 0.18um CMOS technology. Two $4{\times}4$ channel TIA arrays including a voltage-mode INV-TIA and a current-mode CG-TIA are introduced. First, the INV-TIA consists of a inverter stage with a feedback resistor and a CML output buffer with virtual ground so as to achieve low noise, low power, easy current control for gain and impedance. Second, the CG-TIA utilizes a bias from on-chip bandgap reference and exploits a source-follower for high-frequency peaking, yielding 1.26 times smaller chip area per channel than INV-TIA. Post-layout simulations demonstrate that the INV-TIA achieves 57.5-dB${\Omega}$ transimpedance gain, 340-MHz bandwidth, 3.7-pA/sqrt(Hz) average noise current spectral density, and 2.84mW power dissipation, whereas the CG-TIA obtains 54.5-dB${\Omega}$ transimpedance gain, 360-MHz bandwidth, 9.17-pA/sqrt(Hz) average noise current spectral density, and 4.24mW power dissipation. Yet, the pulse simulations reveal that the CG-TIA array shows better output pulses in the range of 200-500-Mb/s operations.

• The Korean Journal of Food And Nutrition
• /
• v.25 no.4
• /
• pp.1027-1032
• /
• 2012

We investigate the changes of fatty acids in blood for an evaluation of the effects of soft and enteric coated capsules containing omega 3 fatty acids. Fish oil, which contained 62.87 g/100 g of sum of EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid), was used as nutracueticals for omega 3 fatty acids. Lipid releasing amount in soft capsule was 70% in stomach condition. However, there was 10% of releasing amount of lipid observed in enteric coated capsule in stomach condition. In intestinal condition, 50% of lipid releasing amount in enteric coated capsule showed until 6 hr, but soft capsule until 90 min. EPA and DHA contents in soft capsule administration showed higher level than those in enteric coated capsule until 8 hr. However, the administration of enteric coated capsule showed higher level of EPA and DHA in blood after 8 hr. After 24 hr, mono-, poly-unsaturated and saturated fatty acids contents with enteric coated capsule showed higher level than those with soft capsule. The enteric coated capsule containing omega 3 fatty acids was expected to sustain omega 3 fatty acids.

• Korean journal of food and cookery science
• /
• v.26 no.1
• /
• pp.13-17
• /
• 2010

The antioxidant activity of commercial sweet persimmon wine concentrate (SPWC) was evaluated by determining the total phenol content (TPC), 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity, reducing power (RP), and 2,2-azino-bis-(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) radical scavenging activities. TPC in the SPWC was $9.29{\pm}0.11\;mg$ gallic acid equivalents (GAE)/g, which corresponds to 31.59 mg GAE/100 mL of the wine. The IC50 for the DPPH radical scavenging activity, RP, and ABTS radical scavenging activity of SPWC were 2.96, 1.44, and 0.48 mg/mL, respectively. The neuroprotective effect of SPWC against glutamate-induced neurotoxicity in N18-RE-105 cells was investigated. Treatment of N18-RE-105 cells with various SPWC concentrations under glutamate resulted in the induction of a protective effect in a dose-dependent manner, as determined by the MTT reduction assay. These results suggest that SPWC exhibits considerable antioxidant and neuroprotective activity.

• Korean Journal of Remote Sensing
• /
• v.34 no.5
• /
• pp.763-775
• /
• 2018

In this study, the effects of wind fences on the dispersion of the particles emitted from a constructing site located in the building-congested area in Busan, Korea, using geographic information system (GIS) and a computational fluid dynamics (CFD) model. We averaged the wind speeds observed for 10 years at the Busan automated synoptic observing system (ASOS) and we used the averaged wind speed as the wind speed at the reference height (10 m above the ground level). The numerical simulations were performed for 16 inflow directions, before and after the construction of wind fences with the heights of 5 m and 10 m (total 48 simulations). The detailed flows were analyzed for the northeasterly and south-southwesterly cases which predominantly observed at the Busan ASOS. In the northeasterly case, high concentration appeared at the elementary school next to the construction site due to transport by the airflow coming from the northeast. In the 5-m wind fence case, the wind speeds were slightly weaker and the spread of the fugitive dust was slightly less than those in the no wind fence case. In the 10-m wind fence case, the dust concentration at the elementary school has the maximum reduction of 37%. In the south-southwesterly case, the flow pattern became complicated in the construction site due to the terrain and buildings. Fugitive dust was stagnant at the south side of the construction site but rather spread to the north, increasing the concentration at the elementary school. After the wind fence was built, the concentrations inside the construction site became high as the wind speeds decreased inside, but, the concentrations in the elementary school rather decreased.

• The Journal of the Korean bone and joint tumor society
• /
• v.1 no.1
• /
• pp.84-90
• /
• 1995

To evaluate the role of radiation and chemotherapy after limb-saving operation in the management of soft tissue sarcoma, the authors analysed retrospectively 33 patients treated in department of Orthoaepdic Surgery and Radiation Therapy, Catholic University Medical College, in terms of survival rate, local recurrence rate and prognostic factors. There were 16 males and 17 females. The age distribution ranged from 16 to 81 years with mean age of 48. The follow-up period ranged from 2 to 10 years with average of 5.5 years. The histologic diagnoses were 9 liposarcoma(27.2%), 8 malignant fibrohistiocytoma(24.2%), 7 unclassifiable(21.2%), 3 rhabdomyosarcoma(9.1%), 2 malignant schwannoma, 2 synovral sarcoma, and 2 fibrosarcoma(6.1%) in orders. While marginal and intralesional margins were gained in 24 patients(72.7%), wide and radical margins were obtained only in 9 patients(27.3%). On postoperative 3 weeks, local irradiation of 5000-7000 cGy was delivered to all patients by shrinking field technique for 5-8 weeks. Of 33 patients, 16(45.5%) patients were received adjuvant chemotherapy in combination of adriamycin, cyclophosphamide & vicristine, or VP16 & ifosfamide based on histologic type and obtained surgical margin. The survival rates by direct method at 2 years and 5 years were 58% and 37% respectively. Local recurrences occured in 15 patients(45.5%) at average 16 months after operation. Survival rates at 2 years and 5 years were 37% and 22% in case of intralesional and manginal excision, 75% and 47% in case of wide and radical excision respectively with statistical significance(p<0.05). They were 25% and 17% in the presence of local recurrence, 67% and 42% in the absence of local recurrence respectively with statistical significance(p<0.05). Even though there was no statistical correlation between survival rate and tumor size(p>0.05), the authors considered tumor size as a significant prognostic factors as well as surgical margin and the presence of local recurrence.

• Journal of Food Hygiene and Safety
• /
• v.26 no.1
• /
• pp.43-48
• /
• 2011

For the application of nano-sized material in various fields, the evaluation of nano-sized material toxicity is important. In the present study, various concentrations of 200 nm-sized silicon dioxide nanoparticle suspension were intraperitonially injected into mice to identify the toxicity of silicon dioxide nanoparticle in vivo. In the hematological analysis of group II treated with silicon dioxide nanoparticle 100 mg/kg body weight, lymphocytes and monocytes were significantly different compared to the control group. In group III treated with silicon dioxide nanoparticle 200 mg/kg body weight, lymphocytes, monocytes and hemoglobin were significantly different compared to the control group. In blood biochemical analysis of group III, the concentration of AST, ALT, BUN, and creatinine were significantly different compared to the control group. Histopathologic examination of the kidney indicated a mild injury only in mice received 200 mg/kg silicon dioxide nanoparticle. According to the results of the present study, the significant differences in the hematological and blood biochemical analyses and abnormal histopathological findings in the mouse kidney may have been related to exposure to silicon dioxide nanoparticle.

• Korean Journal of Ichthyology
• /
• v.5 no.2
• /
• pp.151-159
• /
• 1993

Greeling, Hexagrammos otakii Jordan et Starks is commonly found at the coastal waters of Korea and Japan. The authors carried out the artificial insemination in the laboratory on Dec, 17, 1987, and reared the hatched larvae in an aquarium. The eggs were demersal and adhesive, and their diameters were 2.00~2.15mm. Color of yolk was light yellow in the early stage, and then turned to orange before hatching. The yolk had numerous tiny oil globules. Hatching began about 477hours after insemination under water temperature of $10.0{\sim}14.5^{\circ}C$. The newly hatched larvae were elongate in shape and 7.48~8.25mm in total length(TL) with 49~50 myomeres. The larvae absorbed the yolk material and oil globules completely in 5days after hatching and became postlarvae. In 17days after hatching, mean total length of the larvae was 9.85mm, and the caudal notochord flex at $45^{\circ}$. In 23days, total length reached 10.54mm. The part of the fin-fold of the future dorsal and anal fins became high. Spawning season of the Greenling is known to be from November to January in the southern coast of Korea.

• Magazine of the Korean Society of Agricultural Engineers
• /
• v.18 no.1
• /
• pp.4011-4020
• /
• 1976

본논문은 북해도대학심사학위논문으로 총면수 143면인 영문으로 되어 있고 도 48, 표 7, 문묵 66부도, 부표 20면이있음. Plow는 옛부터 발달한 농구이기 때문에 많은 연구가 행하여졌지만 복잡한 물리성을 가준 토양을 대상으로 하는 기계이기 때문에 미해결의 문제도 적지않다. 이견인저항에 대하여 토양의 종류 및 조건을 변경하면서 실제의 포장에서 조직적으로 행한 실험은 극히 적고, 하물며 우리나라의 쟁기에 관한 연구는 거의없다. 본논문은 쟁기의 특징을 구명하고, 그의 개량, 발달에 기여하기 위한 기기자료를 획득코저 실시한 것이다. 1. 쟁기와 플라우의 구조 및 그의 차이 특징을 명백히하고 이체에 걸리는 각종의 저항의 내용 또는 그 비율등에 대하여 과거의 연구성과를 소개하였다. 2. 발달사 ; 플라우는 B.C. 2000년경에 녹각, 목지의 인력용의 경운용구에서 발달하고, 동양이도 기원은 대체로 같고 발달과정이 다를 뿐이다. 쟁기는 양자강연안에 기원을 가진 지나이가 신라와 백제에 도입되여 차차 발달하고, 지역적인 특징을 가지게 되었다. 3. 본장은 쟁기의 견인력에 관한 이론적해석을하고, 쟁기의 진행에 의해 층상으로 전단되는 전단저항을 구하고 쟁기의 표면 및 지측판과 토양과의 마찰력, 그리고 토양의 이동의 관성력을 쟁기의 견인저항에 관련되는 주요한 "힘"으로 생각하고 진행방면, 수직방면의 힘의 성분의 평형을 고려하여 식 10. 12를 유도 하였다. 4. 본장에서는 실험계획, 방법 공시기, 공시포장등을 기록하고, 축력용의 쟁기와 플라우를 사용하여 전지 4종 답 2종의 포장에서 실험하는데 견인력계와 자동경심측정기를 사용하였다. 5. 실험결과 및 고찰; 경심과 견인저항 Dp와의 관계는 식 10. 12와 갈이 표시되고, 실제의 제치를 대입하여 이론식을 유도하였으니 직선에 가까운 관계가 있고, 실험결과는 조금 곡선에 가까워졌다. 그리고, 토양의 물리성이 견인력Dp에의 영향을 세밀히 검토하였다. 쟁기의 견인비저항에 있어서도 식 12에서 {{{{K=AT+ { B} over {T } +C}}}}로 표시할수 있기 때문에 최소치를 표시하는 경심이 존재하고 이값은 쟁기나 플라우폭의{{{{ { 1} over {2 } }}}} 즉 10m정도이고 쟁기는 비저항이 0.llkg/$\textrm{cm}^2$에서 0.39kg/$\textrm{cm}^2$이였다. 그러나 이 비저항도 토양의 물리성이 많은 영향을 미치고 있다. 6. 요약 및 결론 ; 이상의 장에서 검토 고찰한 결과만을 기재하고 플라우는 쟁기에 비해 견인저항 및 비저항이 논에서나 밭에서 대로 나타난 것이 특이하다. 이상의 내용을 지면관계로 3회에 거쳐 요약 발표합니다.

• The Korean Journal of Emergency Medical Services
• /
• v.14 no.3
• /
• pp.57-69
• /
• 2010

Purpose: This study aims to examine perceived safety management in teachers working for young children with disabilities, to grasp the state and problems of safety management and first-aid education at daycare center for young children with disabilities, and to provide basic materials to develop programs for safety management and first-aid education. Results: 1. For the perception items of accident possibility in daycare centers, career with more than 10 years had higher response in 'very high' and 'moderately high' than 'moderately or very low' and statistically significant difference was found(p < .05). 2. For the perception items of accident prevention in daycare centers, no teaches with at least college education thought that 'it was not possible to prevent' and most of them thought that 'it was totally possible to prevent' and statistically significant difference was found(p < .05). 3. For the performance level of safety management and first-aid items, forty and over(4.73) showed higher than age of 20-29(4.32) and 30-39 of age(4.26) and statistically significant difference was found(p < .05). 4. For the knowledge level of safety management and first aid items, the highest religion was found as Christian(16.96), followed by Catholic(15.33), Buddhism(14.91), and no religion(15.81) and statistically significant difference was found(p < .05). 5. For the items of confidence in safety management and first aid, performance level, and knowledge level, teachers who competed safety management and first-aid education( 4,48) had higher performance score than those who did not (4.17) and statistically significant difference was found(p < .05). 6. For the items of confidence in safety management and first aid, performance level, and knowledge level, teachers who competed first-aid education(2.77) had higher confidence than those who did not(2.35) and statistically significant difference was found(p < .05). Conclusion: The results suggest that safety management and first-aid education in teachers working for daycare center for young children with disabilities was closely correlated with knowledge and performance levels. Thus, it is necessary to provide continuous safety management and first-aid education for teachers working for day care center for young children with disabilities through regular in-service training. Also further research should be conducted with all subjects and various regions who contact with young children with disabilities.