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http://dx.doi.org/10.9799/ksfan.2012.25.4.1027

Absorption Evaluation of Enteric Coated Capsules Containing Omega 3 Fatty Acids  

Park, Eu Deum (Dept. of Food and Nutrition, Korea University)
Park, Yooheon (Dept. of Food and Nutrition, Korea University)
Park, Sung-Sun (Chong Kun Dang Healthcare Corp.)
Suh, Hyung-Joo (Dept. of Food and Nutrition, Korea University)
Publication Information
The Korean Journal of Food And Nutrition / v.25, no.4, 2012 , pp. 1027-1032 More about this Journal
Abstract
We investigate the changes of fatty acids in blood for an evaluation of the effects of soft and enteric coated capsules containing omega 3 fatty acids. Fish oil, which contained 62.87 g/100 g of sum of EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid), was used as nutracueticals for omega 3 fatty acids. Lipid releasing amount in soft capsule was 70% in stomach condition. However, there was 10% of releasing amount of lipid observed in enteric coated capsule in stomach condition. In intestinal condition, 50% of lipid releasing amount in enteric coated capsule showed until 6 hr, but soft capsule until 90 min. EPA and DHA contents in soft capsule administration showed higher level than those in enteric coated capsule until 8 hr. However, the administration of enteric coated capsule showed higher level of EPA and DHA in blood after 8 hr. After 24 hr, mono-, poly-unsaturated and saturated fatty acids contents with enteric coated capsule showed higher level than those with soft capsule. The enteric coated capsule containing omega 3 fatty acids was expected to sustain omega 3 fatty acids.
Keywords
enteric coated capsule; omega 3 fatty acid; EPA; DHA;
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Times Cited By KSCI : 3  (Citation Analysis)
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