• Journal of Chest Surgery
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• v.23 no.5
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• pp.844-853
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• 1990

We have performed 27 cases of orthotopic homologous cardiac transplantation using Korean mongrel dogs and one case of sham operation for the evaluation of harmful effect of cardiopulmonary bypass itself on the dog from April, 1989 to June, 1990. Our previous reports have already demonstrated basal hemodynamic and hematologic data on the canine homologous heart transplantation and the fundamental principles of transplantation of the heart. The mean body weight of recipients was 13.2$\pm$1.2kg with a rage of 11 ~ 15kg, and the hemodynamic and hematologic pictures were almost same as the result of previous reports from our hospital, except marked decrease in postoperative platelet count[from 3.18 $\pm$0.80x106/mm3 to 1.41$\pm$0 37x 106/mm3]. Mean survival time was 24.82$\pm$49.40 hours with the longest survival of 264 hours. Donor cardiectomy included coronary vasodilatation with diltiazem, potassium arrest, and the rapid cooling of the heart suspending in the specially designed ice-bath. Median sternotomy provided excellent exposure of the surgical field. 6 \ulcorner0 prolene suture was used for the anastomosis of both atrial cuffs and the great arteries, and we found the fact that stenosis, bleeding, thrombus formation around the anastomotic site could be decreased with the use of everted horizontal mattress suture techniques. Immunosuppression was done with a combination of lower dose Cyclosporin-A, Azathioprine, methyl-prednisolone, but our cases still showed too short survival to worry about graft rejection. Still poor was our quality control of experimental animal, we had much difficulties in postmortem evaluation of the dogs. Low cardiac output due to biventricular failure, intractable supraventricular or ventricular tachyarrhythmia, postoperative massive bleeding, sepsis were most frequent findings that could be thought as a cause of death. A few cases showed subendocardial patch hemorrhage in both ventricular cavity or atrial septum at autopsy, suggesting acute subendocardial infarction. Although our team overcome most of the technical problems of orthotopic heart transplantation, we should pile up further knowledges about donor heart preservation, quality control of animal, infection, rejection, the effect of the cardiopulmonary bypass to improve the results.

• The Journal of Korean Association of Computer Education
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• v.18 no.4
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• pp.31-40
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• 2015

The objective of this study is to develop and implement a smart device based instructional analysis application to enhance the efficiency of teaching in class. The main design features for this application are as follows: first, User Interface(UI) has been simplified to provide teachers a clear and easy-to-understand way to utilize the application. Second, the characteristics of Korean language were considered, such as sentence structure. Third, multi-aspect analysis is possible through adopting three analysis types - Flanders' interaction analysis, Tuckman's analysis, Mcgraw's concentration of instruction analysis. The practical instructional analysis application has been developed through this study, and this user-oriented application will be able to help teachers improve the quality of teaching in class. Also, this study can be a starting point for further researches on design principles of instructional analysis, especially with the recent technology and theories, such as a voice-recognition system, an edutainment applied instruction and an experiential learning.

• Information Systems Review
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• v.7 no.1
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• pp.21-40
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• 2005

IT investment is continuously increasing. Its outcome, however, is not accomplished as easily as originally expected. There have a variety of efforts to overcome this dilemma. In public sector, information resource management (IRM) was suggested as one of the most effective approach for information & IT management. Accordingly, United States has been incorporating the IRM principles into information-related laws since 1980s. However, such efforts were insufficient in Korea. In this study we attempt to compare our information-related laws with United States laws with respect to major components of IRM. Based on this finding, we go one-step further to suggest ways to arrange a new legislation where the IRM would be a foundation for information & IT management.

• The Journal of the Korea Contents Association
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• v.16 no.4
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• pp.211-223
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• 2016

Pro bono, a type of voluntary activity, has been considered important in enhancing desirable voluntary activities in our society. This study conducts research on the concept and sustainability of pro bono activities. In doing that, the study conducts focus group interviews with the pro bono activists who have been doing voluntary works for at least six months. Particularly, the study focuses on how to stimulate the participation of people with expertise in probono voluntary activities. The findings suggest that hub-centers be established in managing and connecting probono activities among probono volunteers and keep them motivated. Even though probono activism assume the principles of voluntarism and no-salary, it is necessary to provide potential probono volunteers with several incentives such as tax break and income tax deduction.

• The Journal of Korean Medicine
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• v.25 no.3
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• pp.169-179
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• 2004

Objectives : The purpose of this study is to research trends in the study of diabetes mellitus and to establish the future direction for its study. Methods : We reviewed oriental medicine papers published in the last twenty-three years(1980-2002). Results : 1. We researched 94 papers in 14 journals and the patterns of study were as follows: experimental studies were 53 (56.3%), reviewed studies were 20 (21.2%), clinical studies were 12 (12.7%) and case reports were 9 (9.8%). 2. The experimental studies (53) were divided into papers on efficiency testing of herbal medications (40) and acupuncture & moxibustion (13). 3. The reviewed studies showed that research has been carried out in the fields of cause, pathogenesis, principles for treating disease, acupuncture and moxibustion, herbal medication, exercise, and relation of sasang (사상) to diabetes mellitus. 4. The clinical studies showed that the research was carried out in the fields of follow up surveys for herbal medication efficiency testing, the relativity of diabetes mellitus to other diseases and sasang (사상). 5. In consequence of researching the case reports, there was no common prescription used meaningfully. Conclusions : We need more studies of diabetes mellitus by reaching for specific therapy.

• Journal of Biosystems Engineering
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• v.31 no.3 s.116
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• pp.203-208
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• 2006

This study was conducted to improve the control performance of a current variable-rate controller for granular fertilizers. Simulation model was developed. Optimized proportional, integral and derivative gains were determined by simulation model using 2nd order PID gain learning algorithm, and these control gains were evaluated through the field tests. Important results of this study are as follows; 1. Principles of pre-existing variable-rate application of granular fertilizers were investigated. 2. Simulation model of a PID controller that could simulate the control system was developed by using Matlab/Simulink program. The program was to determine PID control coefficients through the simulation model and 2nd order PID gain learning algorithm. 3. PID control coefficients obtained from the simulation were applied to the developed model. When the step input was given, Maximum overshoot were 1.96%, rise time were 0.05 sec, settling time were 0.06 sec and steady state error were 0.21 % respectively. 4. The simulation model was verified through field tests. The errors of maximum overshoot were 10%, rise time were 0.11 sec, settling time were 0.40 sec and steady state error were 8% because of loads and noises. Rise time was decreased to one third of that of the pre-existing system. 5. If the speed of a fertilizing machine is $0.3{\sim}0.6\;m/s$ and the maximum rotation speed of a discharging roller is 64 rpm, rise time would be 0.26 sec and fertilizing machine would cover the distance of $0.07{\sim}0.15\;m$ with settling time of 0.4 sec, fertilizing machine would cover the distance of $0.12{\sim}0.24\;m$.

• Korean Journal of Health Education and Promotion
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• v.26 no.4
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• pp.49-62
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• 2009

Objectives: Few studies have focused on health behaviors and health status among teachers even though these are one of principles and values of WHO's Health Promoting Schools. In this study, we described health behaviors and health status among teachers and explored the differences of these by personal and school characteristics. Methods: A stratified and random cluster sampling design was used to obtain a cross-sectional sample. A total of 59 elementary, middle and high schools in Seoul and Gyeonggi areas were included in which 333 teachers (males 40.6%, females 59.4%) participated in this survey. Chi-square tests were conducted with SPSS 17.1. Results: Overall, health behaviors and health status among teachers were better than the general public according to Korea National Health and Nutrition Examination Survey. Male and middle/high school teachers had higher prevalence of alcohol dependence and of driving under the influence of alcohol. Also, their rate of wearing seat belts were lower compare to female. In other hand, female, health and nutrition teachers, rural school teachers had lower prevalence of meeting recommended levels of physical activity. Underweight were more prevalent to them in contrast to male with higher prevalence of obesity. In addition, teachers of health promoting schools were not likely to ride on a car with a drunk driver. They also have a lower prevalence of skipping breakfast and have higher positive perception of health for themselves. Conclusion: Teachers' health should be given higher concerns as a key component of school based health promotion. Gender and age specific programs should be considered to develop health promoting programs for them.

• The Journal of Korean Academic Society of Nursing Education
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• v.10 no.1
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• pp.84-93
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• 2004

Purpose: This study was conducted to investigate the subjective degree of fatigue, the degree of fatigue depending on constitution, and the factors related to fatigue in middle-aged women. Method: Data were collected from 51 patients, registered at Oriental Medicine Hospital in J-city and K-city respectively. The instrument used in this study were the Multidimensional Assessment of Fatigue and the Questionnaire of Sasang Constitution Classification Ⅱ. Data analysis was done SPSS Result: The characteristics of constitution in middle-aged women could be divided into three: twenty six people of Soeumin, thirteen people of Taeumin, and twelve people of Soyangin. The degree of fatigue in middle-aged women: the average score 30.61 out of the total score 40. Subdivision of fatigue scores: common fatigue degree 7.71, distress due to fatigue 7.67, degree of daily activity fatigue 7.43, and fatigue frequency in the previous week 7.84. There were significant differences in the degree of fatigue depending on constitution in middle-aged women(p=.033). This study revealed weight, exercise, and drinking are important factors that can exert influence on the degree of fatigue. Also, there was a big difference in the degree of fatigue depending on constitution. Conclusion: In conclusion, fatigue is one of the difficult problems with middle-aged women. And this study revealed that change in the weight(especially loss of weight), physical exercise, and drinking are important factors that can exert influence on the degree of fatigue. Also, there was a big difference in the degree of fatigue depending on constitution. Therefore it is necessary to develop Korean nursing intervention to providing an appropriate environment where there is the harmony of the dual principles of the negative and positive, and patients can be taken care of properly.

• The Korean Journal of Physiology
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• v.29 no.1
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• pp.61-67
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• 1995

The extract of Ginkgo bibloba (EGb) is a complex mixture of natural products from the Ginkgo leaves and clinically used for the treatment of cerebral and peripheral circulatory disturbances due to its combined activity of several vasoactive principles. In this study we investigated the action of EGb and its mechanism in isolated rabbit corporal smooth muscle to evaluate the possibility of using this material as a pharmacoerecting agent. Strips of rabbit corpus cavernosum were mounted in organ chambers to measure isometric tension. EGb began to exert an relaxing effect at 1 mg/ml in the submaximally precontracted muscle strips with phenylephrine $(PHE,\;5{\times}10^{-6}\;M)$; causing concentration-dependent relaxation with maximal effect at $3{\sim}5\;mg/ml$. That relaxation was partially inhibited by removal of the smooth muscle endothelium or by pretreatment with a NO scavenger, pyrogallol $(10^{-4}\;M)$ or the guanylate cyclase inhibitor, methylene blue $(10^{-4}\;M)$. Pretreatment with EGb (3 mg/ml) inhibited PHE- $(5{\times}10^{-6}\;M)$ or KCI- (20 and 40 mM) induced contraction of muscle strip. In calcium-free high potassium solution EGb depressed the basal tone of the depolarized muscle strip and inhibited calcium-induced contraction when $CaCl_2$ $(10^{-4}\;M)$ was added. These results suggest that EGb relaxes rabbit corpus cavernosal smooth muscle through multiple action mechanisms that include increasing the release of nitric oxide from the corporal sinusoidal endothelium, sequestration of intracytosolic calcium, and maybe a hyperpolarizing action.

• Journal of Gastric Cancer
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• v.16 no.2
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• pp.120-124
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• 2016

Primary squamous cell carcinoma (SCC) of the stomach is a very rare disease. However, the pathogenesis, clinical characteristics, and prognosis of gastric SCC are controversial and remain to be elucidated. Herein, we report a case of primary gastric SCC of the remnant stomach after subtotal gastrectomy. A 65-year-old man was admitted to our hospital due to epigastric discomfort and dizziness. He had undergone subtotal gastrectomy 40 years previously for gastric ulcer perforation. Endoscopy revealed a normal esophagus and a large mass in the remnant stomach. Abdominal computed tomography revealed enhanced wall thickening of the anastomotic site and suspected metachronous gastric cancer. Endoscopic biopsy revealed SCC. Total gastrectomy was performed with Roux-en-Y esophagojejunostomy. A 10-cm tumor was located at the remnant stomach just proximal to the previous area of anastomosis. Pathologic examination showed well-differentiated SCC extended into the subserosa without lymph node involvement (T3N0M0). The patient received adjuvant systemic chemotherapy with 6 cycles of 5-FU and cisplatin regimen, and he is still alive at the 54-month follow-up. According to the treatment principles of gastric cancer, early detection and radical surgical resection can improve the prognosis.