• 한국정보디스플레이학회:학술대회논문집
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• 2006.08a
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• pp.651-654
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• 2006

The inline manufacturing equipment using a combination of the belt source and LPS source which is innovatively designed is introduced for the largesize AMOLED. The features of the inline system include 60sec TACT time, 19 numbers of chambers, non-substrate bending and easy application to very thin TFT substrates for the $4^{th}$ - $8^{th}$ Generation AMOLEDs.

• Genomics & Informatics
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• v.21 no.2
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• pp.16.1-16.14
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• 2023

Coronavirus disease 2019 (COVID-19) is a viral infection produced by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus epidemic, which was declared a global pandemic in March 2020. The World Health Organization has recorded around 43.3 billion cases and 59.4 million casualties to date, posing a severe threat to global health. Severe COVID-19 indicates viral pneumonia caused by the SARS-CoV-2 infections, which can induce fatal consequences, including acute respiratory distress syndrome (ARDS). The purpose of this research is to better understand the COVID-19 and ARDS pathways, as well as to find targeted single nucleotide polymorphism. To accomplish this, we retrieved over 100 patients' samples from the Sequence Read Archive, National Center for Biotechnology Information. These sequences were processed through the Galaxy server next generation sequencing pipeline for variant analysis and then visualized in the Integrative Genomics Viewer, and performed statistical analysis using t-tests and Bonferroni correction, where six major genes were identified as DNAH7, CLUAP1, PPA2, PAPSS1, TLR4, and IFITM3. Furthermore, a complete understanding of the genomes of COVID-19-related ARDS will aid in the early identification and treatment of target proteins. Finally, the discovery of novel therapeutics based on discovered proteins can assist to slow the progression of ARDS and lower fatality rates.

• Korean Journal of Clinical Laboratory Science
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• v.55 no.3
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• pp.203-212
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• 2023

Since the coronavirus disease-2019 (COVID-19) outbreak, it has been generally believed that a medical technologists (MTs) are supposed to perform polymerase chain reaction tests and next-generation sequencing (NGS) in the hospitals. However, many do not recognize that the duty of MT for clinical genetic testing has not been stated in the Medical Laws (72.5% for MT, N=200; 62.8% for students, N=123). In this regard, to evaluate the feasibility of MT's role for NGS genetic testing, we requested our subjects to fill out an online survey and analyzed the data. Among them, it shows that the scope of MT's role, including NGS performance should include clinical genetic testing (99.5% for MT, N=200; 86.8% for students, N=123). Also, questions on clinical genetics, which is associated with both cellular genetics and molecular genetic questions should be included in the National MT License Problem Bank (97.5% for MT; 71.4% for students). Based on these results, the Korean Association of Medical Technologists needs to cooperate synergically with the Academic Association of Biomedical Laboratory Science with respect to genetic education and legislation for the future benefit of both MTs and students.

• Journal of Digital Contents Society
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• v.19 no.3
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• pp.561-567
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• 2018

In this paper, we apply this method to the entire process of smart disaster safety management based on the $4^{th}$ industrial revolution to minimize human, social, economic and environment damage from accidents and disasters, prevention evaluation and disaster information collection analysis and real-time detection of field situation. Prevention of $5^{th}$ generation communication system by analysis, contrast by education and training using virtual reality and augmented reality disaster safety management decision support system intelligent robot for recovery, disaster, discovery, reconnaissance relief, and scale analysis of damages were proposed.

• Journal of Practical Engineering Education
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• v.13 no.3
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• pp.533-544
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• 2021

The purpose of this study is to investigate the structural relationship among psychological contract violation, job burnout, and turnover intention of MZ generation workers in small and medium enterprises. The sample collected through online and offline was 144 units of millennial generation and 140 units of Z generation. The results of analysis using structural equations showed that psychological contract violation had a positive (+) effects on turnover intention and job burnout, and job burnout also had a positive (+) effect on turnover intention. In the relationship between psychological contract violation and turnover intention, job burnout had a partial mediating effect.

• The KIPS Transactions:PartB
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• v.19B no.1
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• pp.1-8
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• 2012

Mosaic is to make a big image by gathering lots of small materials having various colors. With advance of digital imaging techniques, photomosaic techniques using photos are widely used. In this paper, we presents an automatic photomosaic algorithm based on adaptive tiling and block matching. The proposed algorithm is composed of two processes: photo database generation and photomosaic generation. Photo database is a set of photos (or tiles) used for mosaic, where a tile is divided into $4{\times}4$ regions and the average RGB value of each region is the feature of the tile. Photomosaic generation is composed of 4 steps: feature extraction, adaptive tiling, block matching, and intensity adjustment. In feature extraction, the feature of each block is calculated after the image is splitted into the preset size of blocks. In adaptive tiling, the blocks having similar similarities are merged. Then, the blocks are compared with tiles in photo database by comparing euclidean distance as a similarity measure in block matching. Finally, in intensity adjustment, the intensity of the matched tile is replaced as that of the block to increase the similarity between the tile and the block. Also, a tile redundancy minimization scheme of adjacent blocks is applied to enhance the quality of mosaic photos. In comparison with Andrea mosaic software, the proposed algorithm outperforms in quantitative and qualitative analysis.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.16 no.9
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• pp.6397-6402
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• 2015

This research was performed to review operating parameters, optimum condition and check characteristic of microbubble generation for using bubble size distribution according to venturi specification. Optimum operating condition have airflow rate 0.3 LPM, 3 bar(pressure tank) and connecting nozzle directly(without valve), it is advantageous to generate microbubble. In case of characteristic of microbubble generation according to venturi specification, effect that nozzle specification affects bubble size distribution is low impact. But considering performance aspects, when using nozzle that throat diameter 3-4 mm, $D_{50}$ are $54.98-61.19{\mu}m$(D3L15, D4L15), fraction of bubble less than $50{\mu}m$ are 0.326, 0.345. And it is superior to others. Besides, $D_{50}$ and fraction of bubble less than $50{\mu}m$ of throat length 20 mm are $49.40-54.98{\mu}m$, 0.447, respectively And nozzle that throat length 20 mm is relatively tendency to generate microbubble stably.

• Asian-Australasian Journal of Animal Sciences
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• v.13 no.6
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• pp.733-738
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• 2000

The objective of this study was to describe the nature of the inheritance of jumping as a behavioral trait and to analyze quantitatively the jumping height as a measure of vigor in two subspecies of mice. Two subspecies of mice, Yonakuni wild mouse (Y) and $CF_{{\sharp}1}$ laboratory mouse (C), were used as the parental types. Reciprocal mating between these two subspecies was made to produce subsequently the first and second generations. The first generation was $F_1$ (YC) resulting from $Y\;male{\times}C\;female$, and $F_1{^\prime}$ (CY) from $C\;male{\times}Y\;female$. The second generation $F_2$ (YCYC) was from mating $F_1{\times}F_1$ and $F_2{^\prime}$ (CYCY) from $F_1{^\prime}{\times}F_1{^\prime}$. Individuals were treated with a set of direct current shock apparatus at six weeks of age to evoke jumping. The results showed that the ratio between jumping and non jumping mice (J: NJ) for C was 0%:100% (0:1), which means that all C did not jump throughout the experiment, whereas Y was 68%:32% (2:1); and the $F_1$ and $F_2$ showed 65%:35% (2:1) and 51%:49% (1:1), respectively. All $F_1{^\prime}$ and $F_2{^\prime}$ individuals jumped as indicated by the ratio 100%:0% (1:0) for both these two genetic groups. Of the jumped mice, average height of the first three jumping observed for pooled sexes in Y, $F_1$, $F_2$, $F_1{^\prime}$ and $F_2{^\prime}$ were 19.3 cm, 19.3 cm, 18.0 cm, 19.9 cm and 16.4 cm, respectively. The distribution of jumping height showed a tendency to be a normal distribution. The jumping activity and jumping height may be affected by some major genes and polygenes, respectively.

• Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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• v.19 no.5
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• pp.17-22
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• 2005

In this study, a disk-type piezoelectric transformer was fabricated. Its diameter was 50[mm] and thickness was 4.5[mm]. The driving and generating electrode with their gap of 1[mm] were fabricated on the top surface. But the common electrode was fabricated on the whole bottom surface. The electrode surface ratio of driving and generating part on the top surface was the range of 1.4:1 to 3:1. We investigated the electrical characteristics with the variation of its thickness and the electrode surface ratio of driving and generating part in the range of load resistance of 100${[\Omega]}\~70{[k\Omega]}$.. Form the experimental results, their influence on the set-up voltage ratio were investigated quantitively and qualitatively.

• Laboraroty Animal Research
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• v.34 no.4
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• pp.264-269
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• 2018

Cell cycle dysfunction can cause severe diseases, including neurodegenerative disease and cancer. Mutations in cyclin-dependent kinase inhibitors controlling the G1 phase of the cell cycle are prevalent in various cancers. Mice lacking the tumor suppressors $p16^{Ink4a}$ (Cdkn2a, cyclin-dependent kinase inhibitor 2a), $p19^{Arf}$ (an alternative reading frame product of Cdkn2a,), and $p27^{Kip1}$ (Cdkn1b, cyclin-dependent kinase inhibitor 1b) result in malignant progression of epithelial cancers, sarcomas, and melanomas, respectively. Here, we generated knockout mouse models for each of these three cyclin-dependent kinase inhibitors using engineered nucleases. The $p16^{Ink4a}$ and $p19^{Arf}$ knockout mice were generated via transcription activator-like effector nucleases (TALENs), and $p27^{Kip1}$ knockout mice via clustered regularly interspaced short palindromic repeats/CRISPR-associated nuclease 9 (CRISPR/Cas9). These gene editing technologies were targeted to the first exon of each gene, to induce frameshifts producing premature termination codons. Unlike preexisting embryonic stem cell-based knockout mice, our mouse models are free from selectable markers or other external gene insertions, permitting more precise study of cell cycle-related diseases without confounding influences of foreign DNA.