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Association Between Gestational Diabetes Mellitus and Subsequent Risk of Cancer: a Systematic Review of Epidemiological Studies

  • Tong, Gui-Xian;Cheng, Jing;Chai, Jing;Geng, Qing-Qing;Chen, Peng-Lai;Shen, Xin-Rong;Liang, Han;Wang, De-Bin
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.10
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    • pp.4265-4269
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    • 2014
  • Purpose: This study aimed at summarizing epidemiological evidence of the association between gestational diabetes mellitus (GDM) and subsequent risk of cancer. Materials and Methods: We searched Medline, Embase, Cancer Lit and CINAHL for epidemiological studies published by February 1, 2014 examining the risk of cancer in patients with history of GDM using highly inclusive algorithms. Information about first author, year of publication, country of study, study design, cancer sites, sample sizes, attained age of subjects and methods used for determining GDM status were extracted by two researchers and Stata version 11.0 was used to perform the meta-analysis and estimate the pooled effects. Results: A total of 9 articles documented 5 cohort and 4 case-control studies containing 10,630 cancer cases and 14,608 women with a history of GDM were included in this review. Taken together, the pooled odds ratio (OR) between GDM and breast cancer risk was 1.01 (0.87-1.17); yet the same pooled ORs of case-control and cohort studies were 0.87 (0.71-1.06) and 1.25 (1.00-1.56) respectively. There are indications that GDM is strongly associated with higher risk of pancreatic cancer (HR=8.68) and hematologic malignancies (HR=4.53), but no relationships were detected between GDM and other types of cancer. Conclusions: Although GDM increases the risk of certain types of cancer, these results should be interpreted with caution becuase of some methodological flaws. The issue merits added investigation and coordinated efforts between researchers, antenatal clinics and cancer treatment and registration agencies to help attain better understanding.

Effects of Nursing Interventions on Anxiety and / or Stress : A Meta-Analysis (불안 및 스트레스에 대한 간호중재 효과의 메타 분석)

  • 이은옥;송혜향;김주현;이병숙;이은희;이은주;박재순;전경자;정면숙
    • Journal of Korean Academy of Nursing
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    • v.22 no.4
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    • pp.526-551
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    • 1992
  • The purpose of this study was to identify the commonalities of various nursing interventions and effective intervention methods in each intervention through analysis and synthesis of many accumulated research papers. The study analyzed the effects of various nursing interventions on anxiety and /or stress. For this purpose, 64 experimental studies with randomized or nonequivalent control group pre-test-posttest design were selected from journals of medical and nursing schools, the Korean Nurse, the Korean Nurses' Academic Society Journal, the Cetnral Journal of Medicine, the New Medical Journal, the Nurse Monthly, and from theses and dissertations conducted from 1970 to 1991. The selected studies nor classified according to three characteristics : 1) the research samuel, 2) types and methods of nursing interventions, and 3) statistical tests. The following analysis was done : 1) Confirmation of the accuracy of data drawn from each study by paired review, 2) Estimation of the homogenity of pre-test scores of the dependent variable between control and experimental groups warranted the effect size of post-scores, 3) If the homogenity of pre-test scores did not warrant, the change scores from pre-test to post-test were used to estimate the effect size, 4) Use of the effect size of each study among homogenious studies was tested for each intervention method, such as relaxation, information, and touch and /or support. Finally, for the studies not showing homogenity, an ANOVA test was used to identify patterns for each intervention. Some findings are summarized as follow : The effect sizes for relaxation and information were greater than those for touch and /or supportive technique. Studies using random assignment had greater effect sizes than nonrandomized sample studies using the same intervention. For healthy people, group education was more effective than individual teaching. However, for patients, relaxation and touch and /or supportive techniques given on individual basis were more effective than when given in a group situation. Measuring anxiety and stress by biological indicators was less effective than by self-report. Budzynski's relaxation method was the most effective. The more frequently the techniques applied, the larger the effect size. On the bases of these findings, the following recommendations were made : 1. A combination of information, relaxtion, and touch-supportive techniques should be used for greater effect in reducing the level of anxiety and /or stress. 2. Information is the first choice of intervention to reduce the level of anxiety and /or stress of healthy People : other interventions may be added depending on the conditions of the subjects.

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Building Korean Science Textbook Corpus (K-STeC) for research of Scientific Language in Education (교육용 과학언어 연구를 위한 범용 자료로서 과학교과서 말뭉치 K-STeC(Korean Science Textbook Corpus) 구축)

  • Yun, Eunjeong;Kim, Jinho;Nam, Kilim;Song, Hyunju;Ok, Cheolyoung;Choi, Jun;Park, Yunebae
    • Journal of The Korean Association For Science Education
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    • v.38 no.4
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    • pp.575-585
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    • 2018
  • In this study, the texts of science textbooks of the past 20 years were collected in order to systematically carry out researches on scientific languages and scientific terms that have not been noticed in science education. We have collected all the science textbooks from elementary school to high school in the 6th curriculum, the 7th curriculum, and the 2009 revised curriculum, and constructed a corpus comprising of 132 textbooks in total. Sequentially, a raw corpus, a morphological annotated corpus, and a semantic annotated corpus of science terms, were constructed. The final constructed science textbook corpus was named K-STeC (Korean Science Textbook Corpus). K-STeC is a semantic annotated corpus with semantic classification and classification of scientific terms, together with meta information of bibliographic information such as curriculum, subject, grade, and publisher, location information such as chapter, section, lesson, page, and sentence, and structure information such as main, inquiry activities, reference materials, and titles. Throughout the three-year study period, a new research method was created by integrating the know-how of the three fields of linguistic informatics, computer science and science education, and a large number of experts were put in to produce labor-intensive results. This paper introduces new research methodologies and outcomes by looking at the whole research process and methods, and discusses the possibility of future development of scientific language research and how to use the results.

Effectiveness of Cognitive Behavioral Therapy Techniques for Control of Pain in Lung Cancer Patients: An Integrated Review

  • Phianmongkhol, Yupin;Thongubon, Kannika;Woottiluk, Pakapan
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.14
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    • pp.6033-6038
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    • 2015
  • Background: Experience of lung cancer includes negative impacts on both physical and psychological health. Pain is one of the negative experiences of lung cancer. Cognitive behavioral therapy techniques are often recommended as treatments for lung cancer pain. The objective of this review was to synthesize the evidence on the effectiveness of cognitive behavioral therapy techniques in treating lung cancer pain. This review considered studies that included lung cancer patients who were required to 1) be at least 18 years old; 2) speak and read English or Thai; 3) have a life expectancy of at least two months; 4) experience daily cancer pain requiring an opioid medication; 5) have a positive response to opioid medication; 6) have "average or usual" pain between 4 and 7 on a scale of 0-10 for the day before the clinic visit or for a typical day; and 7) able to participate in a pain evaluation and treatment program. This review considered studies to examine interventions for use in treatment of pain in lung cancer patients, including: biofeedback, cognitive/attentional distraction, imagery, hypnosis, and meditation. Any randomized controlled trials (RCTs) that examined cognitive behavioral therapy techniques for pain specifically in lung cancer patients were included. In the absence of RCTs, quasi-experimental designs were reviewed for possible conclusion in a narrative summary. Outcome measures were pain intensity before and after cognitive behavioural therapy techniques. The search strategy aimed to find both published and unpublished literature. A three-step search was utilised by using identified keywords and text term. An initial limited search of MEDLINE and CINAHL was undertaken followed by analysis of the text words contained in the title and abstract, and of the index terms used to describe the article. A second search using all the identified keywords and index terms was then undertaken across all included databases. Thirdly, the reference list of all identified reports and articles were searched for additional studies. Searches were conducted during January 1991- March 2014 limited to English and Thai languages with no date restriction. Materials and Methods: All studies that met the inclusion criteria were assessed for methodological quality by three reviewers using a standardized critical appraisal tool from the Joanna Briggs Institute (JBI). Three reviewers extracted data independently, using a standardized data extraction tool from the Joanna Briggs Institute (JBI). Ideally for quantitative data meta-analysis was to be conducted where all results were subject to double data entry. Odds ratios (for categorical data) and weighted mean differences (for continuous data) and their 95% confidence intervals were to be calculated for analysis and heterogeneity was to be assessed using the standard Chi-square. Where statistical pooling was not possible the finding were be presented in narrative form. Results: There were no studies located that met the inclusion requirements of this review. There were also no text and opinion pieces that were specific to cognitive behavioral therapy techniques pain and lung cancer patients.Conclusions: There is currently no evidence available to determine the effectiveness of cognitive behavioural therapy techniques for pain in lung cancer patients.

A Study on the Removal of Deposited Calcium on the Cotton Fabric. (직물에 침착된 Calcium의 제거에 관한 연구)

  • Han Hae Won;Kahng He Won;Kim Sung Reon
    • Journal of the Korean Society of Clothing and Textiles
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    • v.7 no.2
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    • pp.19-25
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    • 1983
  • The purpose of this study was to investigate the effects of laundry variables and additives on the removal of deposited calcium on the cotton fabric. Samples of calcium deposited fabric was made by treating fabric with $CaC1_2$ and $Na_2CO_3$ solution subsequently. The experimental variables were: 1) NaOH concentration ($0.0001\%$, $0.0005\%$, $0.001\%$, $0.005\%$, $0.01\%$) 2) Alkaline builders(sodium carbonate, sodium meta silicate) 3) Sequestering agents(STPP and EDTA concentration: $0.02\%$, $0.04\%$, $0.06\%$, $0.08\%$, $0.1\%$, $0.15\%$, $0.2\%$) 4) Temperatures($25\pm1^{\circ}C$, $40\pm1^{\circ}C$, $60\pm1^{\circ}C$) 5) Edge-abrasion to the removal of deposited calcium on the cotton fabric. The fabric was washed for 15 minutes in a washing machine(Model: Gold Star WP-3007) or Launder-0-meter(40$\~$45 r.p.m., Toyo Rika Instrument Inc.) and rinsed 3 times per every rinsing time. The amount of calcium deposits on the fabrics was determined by EDTA-back titration methods and edge-abrasion was evaluated by ASTM D 3886 method. The results of this study were as follows: 1) pH of surfactant solution(NaOH concentration) did not influence on the removal of deposited calcium on the cotton fabric. 2) Added alkaline builders did not influence on the removal of deposited calcium on the cotton fabric. 3) It was shown that STPP and EDTA were effective to remove deposited calcium. The removal of deposited calcium on the cotton fabric was proportionally increased with increasing concentration of STPP and EDTA. At high concentration, however, the rate was rather decreased with increasing concentration. 4) The temperature of washing solution did not influence on the removal of dedosited calcium on the cotton fabric. 5) As the removal of deposited calcium on the cotton fabric was increased, the rate of edge-abrasion of the fabric was gradually increased.

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Presence of Leucocratic Granites of the Taebaegsan Region and Its Vicinities (태백산지역과 인근에 분포하는 우백질 화강암체의 존재)

  • Yoo, Jang Han;Koh, Sang Mo;Moon, Dong Hyeok
    • Journal of the Mineralogical Society of Korea
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    • v.26 no.4
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    • pp.263-272
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    • 2013
  • The Taebaegsan region and its vicinities mainly consist of Precambrian granitic gneisses and Cambrian meta-sedimentary rocks. And lots of leucocratic(alkali) granites smaller than the stocks are found here and there. Therefore the presence of leuco-granites is not properly described yet in the former studies. For the effective distinction of several granitic rocks, outcrop characteristics, mineral identification, and petro-chemical properties were studied. Some part of granitc gneisses could be classified into typical metamorphic rocks such as migmatites and banded gneisses. And some shows rather dark appearance with gray quartz and feldspars, and others two mica granites, leucocratic ones etc. But all of leucocratic granites of the region usually show bright milky white to beige color. Since they mainly consist of quartz, feldspars, muscovite, and small amounts of sericites, amphiboles, tourmaline and lepidolite. And all of alkali granites belong to the calc-alkalic, peraluminous and S-type in character. During magmatic differentiation of leucocratic granites, CaO and total Fe contents are clearly decreased than those of the older granitic rocks. On the other hand, magmatic evolution also had induced the greisenization and albitization which enriched the relative amounts of alkali elements such as $K_2O$ and $Na_2O$.

Uranium Concentrations in Groundwater of the Goesan Area, Korea (괴산지역 지하수의 우라늄 함량)

  • Cho, Byong-Wook
    • Economic and Environmental Geology
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    • v.50 no.5
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    • pp.353-361
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    • 2017
  • Uranium concentration in groundwater of the Goesan area was anticipated high because the area contains Ogcheon metamorphic rock zone which partly includes coal bed bearing high uranium content and nearly half of the area is covered by granitic rocks. Groundwater samples collected from 250 wells in five 5 lithology (Ogcheon meta-sandy rock zone (Og1), Ogcheon lower phyllite zone (Og2), Ogcheon pebble bearing phyllite zone (Og3), Jurassic granite (Jgr), Cretaceous granite (Kgr)), of the area were analyzed and equivalent uranium concentrations (e(U)) from 200 rocks near sampled wells were measured using portable gamma spectrometry. Higher median value of e(U) (8.2 mg/kg) was found on Kgr outcrops. The median e(U) value of Og2 was not as high as that of Kgr and similar to those of Jgr, Og1, and Og3 (3.05~3.90 mg/kg). The uranium level in groundwater of the area ranged from 0.01 to $293.0{\mu}g/L$ with a median value of $0.87{\mu}g/L$ which is similar to the national median uranium level of $0.74{\mu}g/L$. The uranium concentration was high in the samples from the Kgr (median $4.74{\mu}g/L$) and low samples from the Og1, Og2, and Og3 (median $0.35{\sim}0.74{\mu}g/L$). The percentage of total samples having uranium level above $30{\mu}g/L$ was 2.8%, on the other hand, that of Kgr is 20.7%, reflecting additional survey on the Kgr area is needed.

Characteristics of the Small Scale Leucocratic Granites in the Eastern Parts of the Taebaegsan Region, Korea (태백산 지역 동부에 분포하는 소규모 우백질 화강암체의 특징)

  • Yoo, Jang-Han;Ryoo, Chung-Ryul
    • The Journal of the Petrological Society of Korea
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    • v.23 no.4
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    • pp.375-383
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    • 2014
  • Precambrian granitic gneisses and Cambrian meta-sedimentary rocks are prevalently distributed in the eastern part of the Taebaegsan region, and biotite granitic batholith of the Jurassic period (?) is found in the southern part of Uljin-si. But small scale leucocratic granitic stocks which commonly found here and there have been rather neglected in the previous studies. The presence of leucocratic granites could be differentiated from the older granitic rocks and biotite granite through the outcrop characteristics, mineral species and geochemical compositions. For the effective comparison between the older granitic rocks and leucocratic ones, pale gray to gray coloured Hongjesa granitic gneiss with granular texture was selectively chosen. The Hongjesa granitic gneiss and biotite granite usually have rather plenty of coloured minerals such as biotite and chlorites. But the leucocratic granites often show sericitic alteration due to the albitization and greisenisation during the post-magmatic alteration, and shows rather bright appearance because of poor amount of coloured minerals. Since all of granitic rocks passed rather high degrees of magmatic differentiation, they belong to calc-alkalic and peraluminous in their characters. Among the alkali elements of the leucocratic rocks $K_2O$ shows higher increase than those of the other granitic rocks, and $Na_2O$ only represents slight decrease than those of the Hongjesa granitic gneiss and Uljin granite. On the other hand, CaO and total Fe content are clearly decreased than those of the Hongjesa granitic gneiss and Uljin granite.

Geochemical Studies on Petrogenesis of the Cretaceous Myeongseongsan Granite in the Northwestern Gyeonggi Massif (경기육괴 북서부에 분포하는 백악기 명성산 화강암의 성인에 대한 지화학적 연구)

  • Yi, Eun Ji;Park, Ha Eun;Park, Young-Rok
    • The Journal of the Petrological Society of Korea
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    • v.26 no.4
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    • pp.327-339
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    • 2017
  • The Cretaceous Myeongseongsan Granite in the northwestern Gyeonggi Massif consists of a major pale pink-colored biotite monzogranite and a minor white-colored biotite alkaligranite. Low Sr and high Ba concentrations, negative Eu-anomalies in REE plot, negative Sr anomalies in spider diagram, a negative correlation between Sr and Rb, and positive correlations between Sr and Ba and $Eu/Eu^*$ indicate that a fractional crystallization of both plagioclase and K-feldspar played a significant role during magma evolution. The Myeongseongsan Granite is plotted in I-& S-type granites on I, S, A-type granite classification scheme. While the biotite monzogranite is plotted in unfractionated I-& S-type granite, the biotite alkaligranite is plotted in fractionated I-& S-type granite, which indicates that the biotite alkaligranite is a more differentiated product. In order to elucidate the nature of the protoliths of the peraluminous Myeongseongsan magma, we plotted in $Al_2O_3/TiO_2$ vs. $CaO/Na_2O$ and Rb/Sr vs. Rb/Ba diagrams, and they suggest that the Myeongseongsan Granite was derived from clay-poor metagreywackes and meta-psammites or their igneous counterparts. Whole-rock zircon saturation temperature indicates that the Myeongseongsan magma was melted at $740-799^{\circ}C$.

A Case Study on Applying Reflective Journal to The Engineering Classes in College (전문대학 공학계열 수업에서의 성찰저널 적용 사례연구)

  • Hong, Yu-Na;Maeng, Min-Jae;Chung, Ae-Kyung;Yi, Sang-Hoi;Kim, Neung-Yeun
    • 전자공학회논문지 IE
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    • v.47 no.1
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    • pp.22-33
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    • 2010
  • The main purpose of this study was to develope a reflective journal and examine its effects on student's academic achievement and self-regulated learning strategies. For this study, 'a structured reflective journal' was designed through the steps of systems approach with the purpose of enhancing student's academic achievement and self-regulated learning strategies, especially meta-cognition and critical thinking. The reflective journal used in this study contained the constructive elements of (1) self-evaluation with 5 likert scale, (2) learning essay, (3) dialogue with peers, and (4) dialogue with professor. A total of 94 freshmen enrolled in one of two sections of the engineering courses(theory-based class and experiment and practice-based class) participated in the study for 8 weeks. A pre-test-post-test design was used to examine the effects of the application of reflective journal on student's achievement and self-regulated learning strategies. For the result, analysis of covariance was conducted to determine whether there were any academic achievement differences and self-regulated learning strategy differences. The results suggested that students were taking advantages of the reflective journal, and there were statistically significant differences in academic achievement in the experiment and practice-based class and self-regulated learning strategies in both classes.