• Title/Summary/Keyword: 4-DAMP

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A literature of study on Xerophthalmia (眼乾燥症에 關한 文獻的 考察)

  • Jeong, Dong-Hwan;Kim, Jong-Han;Choi, Jung-Hwa
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.15 no.1
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    • pp.177-197
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    • 2002
  • The result were achived from 29 kinds of the medical literature of many generation is like this. 1. Oriental medical expressions of Xerophthalmia are "Baksab(白澁)", "Kunsabhonhwa(乾澁昏花)", "Sinsoojanggo(神水將枯)", "Donginkunkyul(瞳人乾缺)", "Taljung(奪精)", etc. "Baksab(白澁)" is very close to Xerophthalmia. 2. The cause of Xerophthalmia is Wind, Wind-heat Pathogen, Damp-heat of spleen and lung, DefIciency of body fluid, Yin-deficiency of liver and kidney, Liver deficiency syndrome, Deficiency of blood, Fire, Fire of deficiency type, Liver heat, etc. 3. In the frequency of prescription used Xerophthalmia are "Sangbakpi-Tang(桑白皮湯)", "Eunkyosan(銀翹散)", etc as Excess type, "Kikookjihwang-Tang(杞菊地黃湯)", "Samooloja hwan(四物五子丸)", etc as Deficiency type. 4. In the frequency of medical herbs of Xerophthalmia use much Rehmannia root nourishing Yin and clearing away heat and Divaricate Saposhnikovia root(expelling pathogenic wind.

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The Comparative study on the IgA Nephropathy and hematuria (요혈(尿血)과 IgA 현증(賢症)에 관(關)한 비교(比較) 고찰(考察))

  • Lee, Jung Won;Kim, Chul Jung
    • Journal of Haehwa Medicine
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    • v.9 no.1
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    • pp.409-421
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    • 2000
  • According to The Comparative study on the IgA Nephropathy and hematuria, the results were as follows. 1. IgA nephropathy is included in category of the hematuria the part in deficiency of liver-kidney and damp-heat in oriental medicine. 2. The symptoms of hematuia is changes in color of urine-bloody, dark brown, or rusty colored-without pain in oriental medicine. 3. It is occured IgA nephropathy due to vacuity exhaustion, fidgetiness, internal damage, imfection. 4. For the medical prescriptions due to IgA nephropathy are used Sogyeeumja, $Dayebunch\check{o}ngeum$(大分淸飮), Dangguieum(當歸飮), $Ch\check{o}ngjangtang$(淸腸湯), Silyungtang(柴岺湯), Kamisagunjatang(加味四君子湯) as hematuria of symtom of IgA nephropathy.

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Design of Robust QFT Controller to Damp Low Frequency Oscillations of Power System (전력계통의 저주파 진동 억제를 위한 강인하 QFT 제어기 설계)

  • 정형환;이정필;김상효;정문규;안병철
    • Journal of Advanced Marine Engineering and Technology
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    • v.25 no.4
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    • pp.833-845
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    • 2001
  • Quantitative Feedback Theory(QFT) has been used to design a robust power system stabilizer(PSS) to improve transient and dynamic stabilities of a power system. This design technique is basically accomplished in frequency domain. The most important feature of QFT is that it is able to deal with the design problem of complicated uncertain plants. A basic idea in QFT design is the translation of closed-loop frequency-domain specifications into Nichols chart domains specifying the allowable range of the nominal open-loop response and then to design a controller by using the gain-phase loop shaping technique. This paper introduces a new algorithm to compute QFT bounds more efficiently. The propose QFT design method ensures a satisfactory performance of the PSS under a wide range of power system operating conditions.

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Evaluation of the Wear Comfort of Outdoorwear by Skin Wettedness Analyses (Skin Wettedness 분석을 통한 아웃도어웨어의 착용 쾌적성 평가)

  • Jeong, Jeong-Rim;Kim, Hee-Eun
    • Fashion & Textile Research Journal
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    • v.11 no.6
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    • pp.947-952
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    • 2009
  • The purpose of this study is to analyze skin wettedness($w$) used as the rate index of thermal comfort, and to evaluate the wear comfort of outdoorwear. Skin wettedness is widely used to express the degree of thermal comfort. If skin wettedness exceeds a certain threshold, the body feels damp and discomfort. An experiment which consisted of rest(30 min), exercise(30 min) and recovery(20 min) periods was administered in a climate chamber with 10 healthy male participants. Two kinds of outdoorwears made of 100% cotton fabrics (Control) and specially engineered fabrics having feature of quick sweat absorbency and high speed drying fabric (Functional) were evaluated in the experiment. The condition of climate chamber was controlled according to the thermal insulation of 4 kinds of experimental ensembles(E1~E4). Total sweat loss, sweat loss absorbed into clothing and skin temperature were measured. Skin wettedness was calculated from the ratio of evaporative rate to the maximal evaporative capacity. Skin wettedness of 'Functional' was lower than 'Control' in the 3 kinds of ensembles(E1, E2, E4) because the materials of 'Functional' were composed of quick sweat absorbency and high speed drying fabrics, water vapour permeability and waterproof fabrics.

A Study on 'Specially Selecting Yangming' in 『Suwen·Weilun』 (『소문(素問)·위론(痿論)』의 독취양명(獨取陽明)에 대한 고찰)

  • Ahn, Jin-hee;Suh, Jun-ho
    • Journal of Korean Medical classics
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    • v.32 no.4
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    • pp.91-107
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    • 2019
  • Objectives : The purpose of this paper is to study how medical experts understood 'Specially Selecting Yangming' for clinical application. Methods : After collecting medical texts related to 'Specially Selecting Yangming', its meaning and clinical application were examined thoroughly. Results : 1. The meaning of 'Specially Selecting Yangming' was identified in different ways according to the meaning of 'Yangming.' It was perceived as Stomach, Yangming meridian, Stomach meridian of Foot Yangming, Spleen and Stomach, Intestine and Stomach by medical experts. 2. Chen Wu-ze and Liu Wan-su understood Wei disease as a form of consumption, and regarded 'Specially Selecting Yangming' as tonifying Yangming while Zhang Zi-he put emphasis on Communicating Stomach Qi(胃氣) through vomiting or purgation. Sun Yi-kui insisted on applying it as a precaution. 3. Li Dong-yuan emphasized the cause of Wei disease to be Damp-Heat in the Summer and suggested Qingshuyiqitang and Qingzaotang as remedy. 4. Zhu Zhen-heng's Purging the South and Reinforcing the North is a more fundamental way of treating Wei disease by stimulating the Water-Fire Axis. Conclusions : Through a diachronic study of 'Specially Selecting Yangming' and its remedy, most medical experts regarded 'Specially Selecting Yangming' as tonifying Yangming, but tonifying Liver and Kidney was thought to be a more fundamental treatment.

Study on the Association of PSQI, IQ, BDI and DSOM in the Insomnia Patients(l) (불면환자의 수면의 질 척도, 우울척도, 한방진단시스템과의 연관성 연구(1))

  • Oh, Kyong-Min;Kim, Bo-Kyong
    • Journal of Oriental Neuropsychiatry
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    • v.20 no.3
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    • pp.89-119
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    • 2009
  • Objectives : This study was to investigate the association of Pittsburgh Sleep Quality Index(PSQI), Insomnia Questionaire(IQ), Beck Depression Inventory(BDI) and Diagnos system of oriental medicine(DSOM) in the Insomnia Patients. Methods : For this study, we carried out PSQI, IQ, BDI and DSOM of 37 patients with insomnia who have come to Donguei oriental hospital of Donguei university from November 2008 to May 2009. And Using cross tabulation analysis, verified the association of PSQI, IQ, BDI and DSOM. Results : 1. The most Frequent Pathogenic Factor is blood-deficiency(血虛) in total patients. 2. The score of BDI has positive correlation with sc10 of deficiency of qi(氣虛), damp(濕), kdney(腎) in total patients. 3. The score of PSQI has positive correlation with zp of liver(肝) in total patients. 4. The score of PSQI has positive correlation with sc10 and zp of insufficiency of Yin(陰虛), and the score of BDI has positive correlation with sc10 of blood stasis(血瘀) and zp of liver(肝) in female patients. 5. The score of PSQI has positive correlation with sc10 of deficiency of qi(氣虛) and zp of heart(心), and the score of IQ has positive correlation with sc10 of liver(肝) in male patients. 6. The duration from onset in the group of 22-59years are longer than the group of 60-80 years and the duration of using hypnotics have positive correlation with total sleep time in 22-59years group. 7. The score of PSQI has positive correlation with zp of liver(肝) in 22-59years group. 8. The score of PSQI has positive correlation with the score of BDI in 60-80years group. 9. The score of BDI has positive correlation with sc10 of deficiency of qi(氣虛) and zp of blood-deficiency(血虛), and the score of IQ has positive correlation with zp of coldness(寒) in 60-80years group. 10. The score of IQ has positive correlation with sc10 and zp of dryness(燥) in below 6 Months Group. 11. The score of PSQI has positive correlation with the score of BDI in over 6 Months Group. 12. The score of PSQI has positive correlation with zp of liver(肝) in over 6 Months Group. 13. The score of IQ has positive correlation with sc10 of dryness(燥) in BDI 2nd Grade Group. 14. The score of BDI has positive correlation with sc10 of kidney(腎) and the age has positive correlation with zp of heart(心) in BDI 3rd Grade Group. 15. The age has positive correlation with sc10 of damp(濕) in BDI 4th Grade Group. Conclusions : This study provides insights into the complicated associations of the pattern of insomnia with depression and Diagnos system of oriental medicine. And especially this study showed apparent correlation between insomnia and depression in 60-80years group and over 6 months group.

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Reliability Study of Diagnosis System of Oriental Medicine DSOM(r) D.1.1 (한방진단(韓方診斷)시스템 DSOM(r)D.1.1의 신뢰도연구(信賴度硏究))

  • Lee Ji-Hang;Cho Hye-Sook;Kim Mi-Jin;Yeum Yun-Kyung;Yu Ju-Hee;Lee Yong-Tse;Ji Gyue-Yong;Kim Jong-Won;Kim Kyu-Kon;Lee In-Seon
    • The Journal of Korean Medicine
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    • v.27 no.2 s.66
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    • pp.23-35
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    • 2006
  • Objectives : This study examined the reliability of disease mechanism diagnosis, to evaluate items of questionnaires and inquire about the relationships between disease mechanisms and 'diagnosis program' questionnaires used for the objective diagnosis of Oriental medicine in the department of Oriental OB&GYN, Oriental Medical Hospital of Dongeui University. Method : We analyzed the results of questionnaires from 3504 outpatients of OB&GYN disease at the Oriental Medical Hospital of Dongeui University from April 2000 to April 2005. Results & Conclusions : 1. The research questionnaire had 188 questions, the summary questionnaire 137, and the diagnosis questionnaire 80. 2. The reliability of all questionnaires shows above 90% in deficiency of qi, deficiency of Yin, insufficiency of Yang coldness heat syndrome liver and spleen kidney in all, 8 case disease mechanisms. These are higher in the diagnosis questionnaires than in the research questionnaires and the summary questionnaires, except for kidney disease mechanism. 3. Cronbach a of the questionnaires decreased, especially blood deficiency, phlegm, heat syndrome, and insufficiency of Yang; these 4 case disease mechanisms were lower than 0.6. 4. For degree of correspondence of meeting points, both. the diagnosis and the summary questionnaires were above 80% with the exception of the 2 case disease mechanisms heart and blood deficiency. The meeting points of both the diagnosis and research questionnaires were above 80% in the to case disease mechanisms deficiency of qi blood stasis deficiency of Yim insufficiency of Yang damp dryness liver spleen kidney phlegm. 5. The change in the result values of questionnaires was a decreased level of deficiency of qi heat syndrome phlegm damp kidney and raised level of coldness heart disorder of qi dryness 6. The computation degree of disease mechanism in DSOM(r) D.1.1 was much lower on phlegm deficiency of qi heat syndrome disorder of blood, somewhat lower on insufficiency of Yang and higher on coldness than in the two different questionnaires.

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A Study on the Major Symptoms by Each Pattern of Acne Vulgaris (여드름의 변증 유형별 주요 증후에 관한 연구)

  • Jeong, Woo-Yeol;Hong, Eu-Gene;Shin, Jun-Hyuk;Kim, Yoon-Bum;Nam, Hae-Jung;Kim, Kyu-Seok;Lee, Jun-Hee
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.27 no.4
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    • pp.76-86
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    • 2014
  • Objective : This study was performed to find out the differential points of the pattern identification for Acne vulgaris and suggest them to the clinic setting Methods : We searched the papers that suggest patterns identification for Acne vulgaris through China National Knowledge Infrastructure(CNKI), Oriental Medicine Advanced Searching Integrated System(OASIS), Korean Traditional Knowledge Portal(KTKP), Korean Studies Information Service System(KISS). We looked through all the papers, excluded unintended papers, and finally chose some papers that are suitable for inclusion. Then, We extracted all the patterns of Acne vulgaris and chose frequently suggested patterns. Finally we extracted symptoms from selected patterns and arranged them in order of frequency. Results and Conclusions : 1. We found 215 papers and chose 17 papers (Korean : 6, Chinese : 11). 2. We extracted total 67 demonstrations and chose Patterns of Wind-Heat, Damp-Heat, Phlegm and Static blood, Disharmony of the Thoroughfare and Controlling vessels. 3. In Acne vulgaris, the pattern of Wind-Heat tends to have a red papule, sometimes pustule, pain with itching, burning sensation, tidal reddening of the cheeks, white head or black head. The pattern of Damp-Heat tends to have a pustule, node, redness and swelling, pain and greasy skin. The pattern of Phlegm and Static blood has a tendency to be a nodule or cystoma that is hard, dark, painful, long lasting and hard to recover and easy to recur with a scar, pimple, pigmentation. The pattern of Disharmony of the Thoroughfare and Controlling vessels tends to be exacerbated before menstruation, have a small papule that is not easily treated under the chin or around the mouth.

A Comparison Analysis on the Efficiency of Solar Cells of Shingled Structure with Various ECA Materials (다양한 ECA 소재를 활용한 shingled 구조의 태양전지 효율 비교 분석)

  • Jang, Jae Joon;Park, Jeong Eun;Kim, Dong Sik;Choi, Won Seok;Lim, Donggun
    • Journal of the Korean Solar Energy Society
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    • v.39 no.4
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    • pp.1-9
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    • 2019
  • Modules using 6 inch cells have problems with loss due to empty space between cells. To solve this problem made by shingled structure which can generate more power by utilizing empty space by increasing the voltage level than modules made in 6inch cell. Thus, in this paper, the c-Si cutting cells were produced using nanosecond green laser, and then the ECA was sprayed and cured to perform cutting cell bonding. Three types of ECA materials (B1, B2, B3) with Ag as the main component were used, and experimental conditions varied from 5 to 120 seconds of curing time, 130 to $210^{\circ}C$ of curing temperature, and 1 to 3 of curing numbers. As a results of experiments varying curing time, B1 showed efficiency 19.88% in condition of 60 seconds, B2 showed efficiency 20.15% in 90 seconds, and B3 showed efficiency 20.27% in 60 seconds. In addition, experiments with varying curing temperature, It was confirmed highest efficiency that 20.04% in condition of $170^{\circ}C$ with B1, 20.15% in condition of $150^{\circ}C$ with B2, 20.27% in condition of $150^{\circ}C$ with B3. These are because the Ag particles are densely formed on the surface to make the conduction path. After optimizing the conditions of temperature and curing time, the secondary-tertiary curing experiments were carried out. as the structural analysis, conditions of secondary-tertiary curing showed cracks that due to damp heat aging. As a result, it was found that the ECA B3 had the highest efficiency of 20.27% in condition of 60 seconds of curing time, $150^{\circ}C$ of curing temperature, and single number of curing, and that it was suitable for the manufacture of Solar cell of shingled structure rather than ECA B1 and B2 materials.

Effects of Stress-Induced Sterile Inflammation on the Development of Depression (스트레스로 유발된 무균 염증이 우울증 발생에 미치는 영향)

  • Mi Kyoung Seo;Jung Goo Lee;Dae-Hyun Seog;Se Young Pyo;Won Hee Lee;Sung Woo Park
    • Journal of Life Science
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    • v.33 no.12
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    • pp.1062-1073
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    • 2023
  • Although depression is a common psychiatric disorder that negatively affects individuals and societies, its exact pathogenesis is not well understood. Stress is a major risk factor for depression and is known to increase susceptibility by triggering inflammation. Indeed, many preclinical and clinical studies have suggested a strong link between depression and inflammation. Depression is associated with increased levels of pro-inflammatory cytokines, such as interleukin (IL-)1β, IL-6, IL-12, tumor necrosis factor-α, and interferon-γ, and decreased levels of the anti-inflammatory IL-4, IL-10, and transforming growth factor-β. Administering pro-inflammatory cytokines causes depression-like behaviors in rodents. Conversely, administering anti-inflammatory drugs appears to ameliorate depressive symptoms. Although the importance of inflammation as a mediator of depression has been demonstrated, the mechanisms by which inflammation is activated in depression remain unclear. To address this issue, recent studies have focused on the importance of stress-induced sterile inflammation. Sterile inflammation refers to the activation of inflammatory processes due to physical and/or psychological stress in the absence of pathogens. Stress promotes the release of endogenous factors known as damage-associated molecular patterns (DAMPs), thereby triggering sterile inflammation. In turn, DAMPs are recognized by pattern recognition receptors, leading to the production of pro-inflammatory cytokines. Here, we review the role of DAMPs in depression based on preclinical and clinical evidence on the dysregulation of sterile inflammation.