• Title/Summary/Keyword: 4-BAR

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Effects of Ojeoksangamibang on the Lipid Metabolism, Anti-oxidation and Concentration of Proinflammatory Cytokines in Rat Fed High Fat Diet (오적산가미방(五積散加味方)이 고지방식이 유도 비만쥐의 지질대사, 항산화계 및 전염증성 cytokine 생산에 미치는 영향)

  • Kong, In-Pyo;Park, Won-Hyung;Cha, Yun-Yeop
    • Journal of Korean Medicine Rehabilitation
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    • v.21 no.4
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    • pp.23-40
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    • 2011
  • Objectives: This study was designed to examine the effects of extracts of Ojeoksangamibang($W{\check{u}}j\bar{i}s\check{a}nji\bar{a}w\grave{e}if\bar{a}ng$) on the lipid lowering, anti-oxidation and concentration of proinflammatory cytokines and was investigated on hyperlipidemic rats. Methods: Male rats weighing $182.39{\pm}4.71g$ were fed high fat diet for 8 weeks and 36 rats(above 400 g) were divided into 4 groups. Each of 9 rats was divided a control group and experimental groups. We fed a control group of rats a basal diet and administered normal saline(100 mg/kg, 1 time/1 day) for 4 weeks. And we fed each experimental group of rats basal diet and administered an extract of Ojeoksangamibang($W{\check{u}}j\bar{i}s\check{a}nji\bar{a}w\grave{e}if\bar{a}ng$) extracts(100 mg/kg, 200mg/kg, 300 mg/kg, 300 mg/kg, 1 time/1 day) for 4 weeks. At the end of the experiment, the rats were sacrificed to determine their chemical composition. We measured lipid of plasma and liver, concentration of proinflmmatory cytokines, anti-oxidative activity and $TNF-{\alpha}$, Apo-B, Apo-E and leptin gene expression. Results: 1. Concentration of plasma free fatty(FFA) showed no significant difference in all the treatment groups. Concentration of plasma triglyceride(TG) showed a significant decrement in the 300 mg/kg in Ojeoksangamibang($W{\check{u}}j\bar{i}s\check{a}nji\bar{a}w\grave{e}if\bar{a}ng$) groups than that of control group. 2. Concentration of plasma total cholesterol showed a significant decrement in the 200 and 300 mg/kg in Ojeoksangamibang($W{\check{u}}j\bar{i}s\check{a}nji\bar{a}w\grave{e}if\bar{a}ng$) groups than that of control group. Concentration of plasma low density lipoprotein(LDL)-cholesterol showed a Significant decrement in the 300 mg/kg in Ojeoksangamibang($W{\check{u}}j\bar{i}s\check{a}nji\bar{a}w\grave{e}if\bar{a}ng$) groups than that of control group. Concentration of plasma high density lipoprotein(HDL)-cholesterol showed a significant increment in the 300 mg/kg in Ojeoksangamibang($W{\check{u}}j\bar{i}s\check{a}nji\bar{a}w\grave{e}if\bar{a}ng$) group. 3. Concentration of liver total cholesterol showed a tendence to decrease in Ojeoksangamibang($W{\check{u}}j\bar{i}s\check{a}nji\bar{a}w\grave{e}if\bar{a}ng$) groups. Concentration of liver TG showed a significant decrement in all Ojeoksangamibang groups than that of control group. 4. Concentration of plasma and liver thiobarbituric acid reactive substance(TBARS) showed a tendence to decrease in Ojeoksangamibang($W{\check{u}}j\bar{i}s\check{a}nji\bar{a}w\grave{e}if\bar{a}ng$) groups. 5. The values of glutathione peroxidase(GSH-Px), superoxide dismutase(SOD) and catalase(CAT) activity showed a significant increment in all Ojeoksangamibang($W{\check{u}}j\bar{i}s\check{a}nji\bar{a}w\grave{e}if\bar{a}ng$) groups than that of control group. 6. The values of plasma aspartate aminotransferase(AST) and alanine aminotransferase(ALT) activity showed no significant different in all treatment group. 7. Concentration of plasma $interleukin(IL)-1{beta}$ showed no significant difference in all the treatment groups. Concentration of plasma IL-6 showed a significant decrement in the 300 mg/kg in Ojeoksangamibang($W{\check{u}}j\bar{i}s\check{a}nji\bar{a}w\grave{e}if\bar{a}ng$) group than that of control group. Concentration of plasma tumor necrosis $factor-{\alpha}(TNF-{\alpha})$ a siginifant decrement in the 200 and 300 mg/kg in Ojeoksangamibang($W{\check{u}}j\bar{i}s\check{a}nji\bar{a}w\grave{e}if\bar{a}ng$) group than that of control group. However the concentration of plasma IL-10 in the 300 mg/kg Ojeoksangamibang($W{\check{u}}j\bar{i}s\check{a}nji\bar{a}w\grave{e}if\bar{a}ng$) groups showed a significant increment than that of control group. 9. In the analysis of reverse transcription-polymerase chain reaction(RT-PCR), gene expression of $TNF-{\alpha}$, Apo-B and Apo-E in the Ojeoksangamibang($W{\check{u}}j\bar{i}s\check{a}nji\bar{a}w\grave{e}if\bar{a}ng$) groups showed a lower expression than that of control group. However the gene expression of leptin showed no difference in the treatment groups. 10. The ratio of $TNF-{\alpha}$, Apo-B, and Apo-E per ${\beta}-actin$ expression in the Ojeoksangamibang($W{\check{u}}j\bar{i}s\check{a}nji\bar{a}w\grave{e}if\bar{a}ng$) groups showed a significant decrement than that of control group. However The ratio of leptin expression per ${\beta}-actin$ expression showed no significant difference among all the treatment groups. Conclusions: According to above results, in lowering lipid effect, anti-oxidation and control of pro-inflammatory cytokines production, Ojeoksangamibang($W{\check{u}}j\bar{i}s\check{a}nji\bar{a}w\grave{e}if\bar{a}ng$) gives effect.

Irradiation Test of Bar Code Label (바코드 라벨의 방사선 조사시험)

  • 배상민;이강무;손종식;홍권표;고병령
    • Proceedings of the Korean Radioactive Waste Society Conference
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    • 2003.11a
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    • pp.544-548
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    • 2003
  • The Irradiation test of bar code label tagged on radioactive waste container was done to determine the effect of radiation. Low and medium radioactive waste is that below total activity of 4,000 Bq/g according to the Korean nuclear law. The irradiation amount to radiate bar code label tagged on radioactive waste container was calculated by MCNP-4b computer code. The nuclide such as Co-60 and Cs-137 was assumed to contribute 50% of total activity. Real irradiation amount for bar code label was finally calculated by the dimensions of the container and the bar code label. The Identification of post and the physical deflection of irradiated bar code label was tested by the bar code reader. The coated bar code label was suitable to use on low and medium radioactive waste container.

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A study on the adhesion of HTPB liner and PCP propellant (HTPB 라이너와 PCP 추진제와의 접착에 관한 연구)

  • 홍명표;서태석;임유진
    • Journal of the Korean Society of Propulsion Engineers
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    • v.5 no.3
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    • pp.60-70
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    • 2001
  • The study of compatible liner with ADP-505 propellant based PCP was performed. HTPB/DDl was chosen as a binder of liner in order to prohibit migration of nitroester plasticizer from propellant. The possible formulations for liner were screened by peel test of EPDM insulation/liner, propellant/liner and insulation/liner/propellant. Also, the adhesion tests including tension and shear were conducted. The adhesion of liner and propellant fumed out to be very good. The peel value was shown 1.5∼1.8 daN/cm, tensile force was 5.5∼6.0bar and shear force was 4.2∼5.0bar. In the samples of insulation/liner/propellant, they also have shown good adhesion properties. The peel, tensile and shear strength were 1.8 daN/cm, 5.0∼6.0bar and 4.5∼5.0bar, respectively.

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A STUDY ON THE CHANGES IN RETENTION OF CLIPS USED TO RETAIN IMPLANT-SUPPORTED OVERDENTURE (임플랜트지지 overdenture용 clip의 유지력 변화에 관한 연구)

  • Yeo, Dong-Heon;Lim, Ju-Hwan;Cho, In-Ho
    • The Journal of Korean Academy of Prosthodontics
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    • v.36 no.4
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    • pp.566-580
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    • 1998
  • Implant-supported overdenture is known as a useful appliance, instead of using the conventional complete denture, for better retention and stability. In this study 4 types of materials such as, gold bar/plastic clip(group AuP), gold bar/metal clip(group AuM), palladium bar/plastic clip(group PdP), and palladium bar/metal clip (group PdM) were used to evaluate the retention forces according the type of clips and alloys used for bar fabrication, in the Hader bar system. Repeated insertions and removals of overdenture were conducted in each group. and the retention forces were measured and compared the data of each group according to the number of insertion and removal. The obtained results were as follows, 1. In the comparison of retention forces according to type of bar-clip, retention was increased in the order of group AuM, PdM, PdP AuP. and the retention force of group AuM was significantly increased compared with those of others (p<0.05). 2. In the comparison of retention forces according to the number of insertion, only group PdP showed significant decrease in retention(p<0.05). 3. In the comparison of retention forces according to the type of bar and clip. there was no significant difference in the type of bar, but the retention of plastic clip was significantly higher than that of metal clip when Au bar was used(p<0.05). 4. In the observation of the bar surface, group AuM using Au bar and metal clip showed the most scratches among bar groups.

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A Comparison Analysis of EMG on Arm and Trunk Muscle Between Elastic and Inelastic Bar During The Overhead Press Exercise (오버헤드 운동 중 탄성 바와 비탄성 바의 팔과 몸통 근육에 대한 근전도 비교 분석)

  • Il Bong, Park
    • Korean Journal of Applied Biomechanics
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    • v.32 no.4
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    • pp.128-133
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    • 2022
  • Objective: This study was executed to compare and analyze shoulder muscle activation while using an inelastic bar and elastic bar during overhead press exercise. The stability and coordination of shoulder joints will be investigated by measuring and analyzing the EMG of the upper and lower arm muscles. Method: A total of 20 university male students were recruited by dividing into 2 groups; 10 elastic bar participants (age: 20.17 ± 0.41 yrs, height: 174.31 ± 3.34 cm, weight: 74.68 ± 5.65 kg) and 10 inelastic bar participants (age: 20.09 ± 0.23 yrs, height: 173.53 ± 4.11 cm, weight: 75.32 ± 3.31 kg) participated in this study. Results: The EMG analysis results of the four muscles measured in this study showed that there was no difference between the left and right muscles between the groups in Upper Trapezius muscle. In Deltoid, Infraspinatus, and Rectus Abdominis muscles, the elastic bar group was significantly higher than the inelastic bar group between groups, and there was no difference between left and right. Conclusion: Among the four muscles measured in this study, there was no difference between left and right in Deltoid, Infraspinatus, and Rectus Abdominis, but the elastic bar showed significantly higher muscle activity than the inelastic bar. Therefore, it was found that the elastic bar increases muscle activation during exercise than the inelastic bar, and in particular, it further increases muscle activation of the arms and torso, and exercise using the elastic bar can increase neuromuscular stabilization.

Stiffness Analysis in a Redundantly Actuated Four-Bar Mechanism (잉여구동을 지닌 4절 기구에서의 강성효과에 대한 해석)

  • 이병주
    • Transactions of the Korean Society of Mechanical Engineers
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    • v.18 no.4
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    • pp.846-855
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    • 1994
  • An effective stiffness, analogous to that of a wound spring, can be created by antagonistic redundant actuation of general closed-chain mechanisms. The qualitative and quantitative characteristics of the effective stiffness are investigated through a Four-bar mechanism, and a load distribution method is introduced which simultaneously guarantees the required system motion and the effective stiffness of the Four-bar mechanism. Furthermore, a simulation is performed to understand the inter-relationship among the effective stiffness, the Four-bar geometry, and the actuation effort. Based on this analysis, the Four-bar synthesis problem for effective stiffness generation is discussed.

Estimation of Paddy Rice Growth Increment by Using Spectral Reflectance Signature (분광반사특성을 이용한 벼의 생장량 추정)

  • 홍석영;이정택;임상규;정원교;조인상
    • Korean Journal of Remote Sensing
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    • v.14 no.1
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    • pp.83-94
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    • 1998
  • To have a basic idea on the spectral reflectance signature in paddy rice canopy, we measured spectral reflectance from paddy rice canopy(Ilpumbyeo) using spectroradiometer (GER Inc. SFOV : 0.35~2.50 ${\mu}{\textrm}{m}$) in situ weekly or biweekly from transplanting to ripening stage. Spectral reflectance of the visible range (0.4~0.7 ${\mu}{\textrm}{m}$) was decreased to below 5% and then slightly increased again after heading stage in rice canopy. Meanwhile spectral reflectance of the near-infrared range (0.7~1.1 ${\mu}{\textrm}{m}$) was increased to 40~50% and then decreased a great deal after panicle initiation stage in rice canopy. Landsat TM equivalent band set ($\bar{p}$$_{TMi}$) was created by averaging spectral reflectance values to the real TM bands. Correlation analysis between the rice crop variables (LAI, total dry matter) and TM equivalent band set ($\bar{p}$$_{TMi}$) showed that LAI and total dry matter of rice were highly correlated with visible bands such as $\bar{p}$$_{TM1}$, $\bar{p}$$_{TM2}$, and $\bar{p}$$_{TM3}$. Ratio values ($\bar{p}$$_{TMi}$/$\bar{p}$$_{TMi}$) such as $\bar{p}$$_{TM4}$/$\bar{p}$$_{TM2}$ were also highly correlated with rice crop variables such as LAI and total dry matter.

Minimization Method of Reading Error in Postal 4 State Bar Code Reader (우편용 4 State 바코드시스템의 판독오차 최소화 방법)

  • 황재각;신미영;박문성
    • Proceedings of the IEEK Conference
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    • 1999.11a
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    • pp.1027-1030
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    • 1999
  • Recently many efforts on the development of automatic processing system for delivery sequence sorting have been performed in ETRI, which requires the use of postal 4 state bar code system to encode delivery points. This paper addresses the issue on the reduction of reading error in postal 4 state raster beam based bar code reader by adjusting measured values of bar code width to its average value over each interval. The test results show that the above method reduces the average reading error rate approximately by 90-100%.

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New emerging surface treatment of GFRP Hybrid bar for stronger durability of concrete structures

  • Park, Cheolwoo;Park, Younghwan;Kim, Seungwon;Ju, Minkwan
    • Smart Structures and Systems
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    • v.17 no.4
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    • pp.593-610
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    • 2016
  • In this study, an innovative and smart glass fiber-reinforced polymer (GFRP) hybrid bar was developed for stronger durability of concrete structures. As comparing with the conventional GFRP bar, the smart GFRP Hybrid bar can promise to enhance the modulus of elasticity so that it makes the cracking reduced than the case when the conventional GFRP bar is used. Besides, the GFRP Hybrid bar can effectively resist the corrosion of conventional steel bar by the GFRP outer surface on the steel bar. In order to verify the bond performance of the GFRP hybrid bar for structural reinforcement, uniaxial pull-out test was conducted. The variables were the bar diameter and the number of strands and pitch of the fiber ribs. Tensile tests showed a excellent increase in the modulus of elasticity, 152.1 GPa, as compared to that of the pure GFRP bar (50 GPa). The stress-strain curve was bi-linear, so that the ductile performance could be obtained. For the bond test, the entire GFRP hybrid bar test specimens failed in concrete splitting due to higher shear strength resulting in concrete crushing as a function of bar deformation. Investigation revealed that an increase in the number of strands of fiber ribs enhanced the bond strength, and the pitch guaranteed the bond strength of 19.1 mm diameter hybrid bar with 15.9 mm diameter of core section of deformed steel the ACI 440 1R-15 equation is regarded as more suitable for predicting the bond strength of GFRP hybrid bars, whereas the CSA S806-12 prediction is considered too conservative and is largely influenced by the bar diameter. For further study, various geometrical and material properties such as concrete cover, cross-sectional ratio, and surface treatment should be considered.