• Korean Journal of Food Science and Technology
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• v.49 no.4
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• pp.369-376
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• 2017

Maturation of distilled spirit can generate diverse flavors and tastes. Rice Soju was matured in oak casks (MSO) and stainless steel containers (MSS) for one year at ambient temperature. Ipguk (Aspergillus luchuensis) and Saccharomyces cerevisiae Y88-4 were used, and reduced pressure ($110{\pm}20Torr$) distillation was applied to brew Soju. Acidity and conductivity were increased in both MSO and MSS. MSO reduced alcohol content (from 43 to 40%) and volume (from 18,000 to 12,730 mL), and significantly altered yellowness (from 0.2 to 30.2). Furthermore, MSO increased the isoamyl alcohol (from 276.7 to $339.2{\mu}g/mL$) and isobutyl alcohol (from 122.3 to $144.2{\mu}g/mL$) content. Gas chromatography-mass spectrometry was used to detect volatile compounds in Soju, which included 20 esters, 7 alcohols, 2 acids, and 5 miscellaneous compounds. Oak lactone was detected only in MSO and was considered as a specific flavor component associated with oak maturation. Thus, maturation materials contribute to the physicochemical property of distilled spirits.

• Korean Journal of Food Science and Technology
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• v.34 no.4
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• pp.604-609
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• 2002

The sensory properties and flavor components of the white bread added with arrowroot juice. The lightness of bread crumb decreased significantly as arrowroot juice was added. While the yellowness increased slightly, redness increased remarkably. The hardness, chewiness and adhesiveness of the white bread added with arrowroot juice increased more than those of the control bread, but they had no statistical significance. While the gumminess increased significantly and springiness decreased significantly, the cohesiveness did not indicate significant differences among the comparison groups. In sensory evaluation, the texture, flavor and sweetness did not indicate significant difference among the comparison groups, while the color and overall acceptability indicated significant difference. The optimum concentration of arrowroot juice in the white bread was 25% based on the sensory evaluation scores. The main flavors components of the white bread added with 25% arrowroot juice were compounds translated by arrowroot juice and the compounds formed by amino-carbonyl reaction. The translated flavors were methoxy phenol, ${\beta}-damascenone$, benzylcyanide, and menthofuran. The compounds formed by amino-carbonyl reaction were alkyl pyrazines, pyrroles and furans.

• Journal of Advanced Navigation Technology
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• v.10 no.3
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• pp.275-281
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• 2006

Simple-relay aided resource allocation (SRARA) schemes are incorporated with throughput guarantee scheduling (TGS) in IEEE 802.16 type time division duplex - orthogonal frequency division multiple access (TDD-OFDMA) downlink in order to enhance service coverage, where the amount of resources for relaying at each relay is limited due to either its available power which is much smaller than base station (BS) power or the overhead required for exchanging feedback information. The performance of SRARA schemes is evaluated with schedulers such as proportional fair (PF) and TGS at 64kbps and 128kbps user throughput requirements when total MS power is set to 500mW or 1 W. For 64kbps throughput requirement level, more improvement comes from relay than scheduler design. For 128kbps case, it comse from scheduler design than relay due to the fact that simple relay can't help using strictly limited amount of resources for relaying function.

• Restorative Dentistry and Endodontics
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• v.30 no.6
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• pp.470-476
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• 2005

The purpose of this Study was to invest)gate the function or calcitonin gene-related peptide (CGRP) in regulatory mechanism of pulpal microcirculation with the aim of elucidating neurogenic inflammation. Experiments were performed on twelve cats under general anesthesia. CGRP was administered through the femoral vein to see the systemic Influence and through the external carotid artery to see the local effect. Sympathetic nerve to the dental pulp was stimulated electrically and pulpal blood flow (PBF) was measured with a laser Doppler flowmeter on the canine teeth to the drug administration. The paired variables of control and experimental data were compared by paired t-test and differences with p < 0.05 were considered statistically significant. Systemic administration of CGRP $(0.3{\mu}g/ka)$ exerted decreases in systemic blood pressure and caused changes in PBF with an initial increase i311owed by decrease and a move marked second increase and decrease. Close intra-arterial (i.a.) injection of CCRP $(0.03{\mu}g/kg)$ resulted in slight PBF increase. The effect of CGRP resulted in no significant increase in PBF in the presence of $CGRP_{8-37}$. The electrical stimulation of the sympathetic nerve alone resulted in PBF decreases. The j.a. administration of CGRP following the electrical stimulation of the sympathetic nerve compensated the decreased PBF. Therefore, CGRP effectively blocked the sympathetic nerve stimulation-induced PBF decrease. Results of the present study have provided evidences that even though the local vasodilatory function of CGRP are weak, CCRP is effectively involved in blocking the vasoconstriction caused by sympathetic nerve stimulation in the feline dental pulp.

• Journal of Radiation Industry
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• v.3 no.1
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• pp.13-18
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• 2009

In earlier investigations, seeds of Perilla frutescens(L.) Britt. cv. Chookyoupjaso were irradiated with 200 Gy gamma ray to generate mutagenesis. The aim of this study is to investigate the effects of a hexane extract from Perilla frutescens (L.) Britt. cv. Chookyoupjaso mutant 45 on the actions of anti-inflammatory activity on inducible nitric oxide synthase, and an identification of the major active compound. The hexane extract from P. frutescens exhibited activity of inhibition of a NO production ($IC_{50}$, $295.1{\mu}g\;ml^{-1}$). The hexane extract was further divided into subfractions by silica-gel chromatogarphy. Inhibition of the NO production by various fractions was assayed in LPS-stimulated RAW 264.7 cells. Among the seven fractions, the 5th fraction was the most effective ($IC_{50}$, $19.5{\mu}g\;ml^{-1}$). The 5th fraction suppressed the expression of protein of iNOS in LPS-induced RAW 264.7 cells, and GC/MS analyses showed that isoegomaketone is a major bio-active compound in the 5th fraction. The result indicated that isoegomaketone has a good potential to be developed as an anti-inflammation agent.

• Proceedings of the Korea Water Resources Association Conference
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• 2017.05a
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• pp.7-7
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• 2017

범람파동 개념에 따르면 하도와 홍수터의 횡적 연결성은 하천 생태계의 생물다양성과 생산성 증대에 중요한 역할을 한다. 제방에 의하여 제내지 홍수터가 하도와 차단된 우리나라 하천에서 생태적 서비스를 증대하기 위해서 횡적 연결성을 복원하는 기술 개발이 필요하다. 횡적 연결성의 복원 기술을 개발하기 위해서는 우선 하도와 홍수터 사이에 생태적 연결성의 현황을 파악하고 연결성을 저해하는 요인을 진단하는 평가 기술 개발이 시급히 요청되고 있다. 따라서 본 연구에서는 제방에 의하여 차단된 제내지 하천환경에서 수리적, 생태적 횡적 연결성을 평가하고 진단하는 기술을 개발하고 연결성 회복 방안을 제안하고자 한다. 차단된 제내지 하천환경 평가는 1) 지리정보시스템을 이용하여 차단된 하천공간을 탐색하고, 2) 탐색된 전체 재내지에서 원격평가에 의하여 간편하게 횡적 연결성 평가를 실시하고, 3) 선정된 특정 제내지 대상지에서 현장평가에 의하여 상세하게 연결성을 평가하는 순서로 수행된다. 차단된 하천공간의 획정은 홍수가 범람할 수 있는 제내지 공간을 잠재적 하천공간으로 정의하고 수치표고모델 (DEM)과 하천기본계획의 30년 빈도 홍수위 자료를 이용하여 제내지 홍수터를 탐색하였다. 제내지 홍수터의 원격 연결성평가는 지리정보시스템에서 수치지도와 토지피복도 등 공간자료를 이용하여 수리 및 서식처 환경성, 제방 차단성과 하도 및 육상 연결성을 평가하고 원격평가 결과를 토대로 현장평가 대상지를 선정하였다. 횡적 연결성의 현장평가를 위하여 크게 하도-홍수터 연결성과 제내지 서식처 보존성으로 평가 항목을 선정하였다. 또한 연결성 평가는 수리연결성과 생물연결성으로, 서식처 보존성 평가는 습지유지율, 습지보존성, 육역지보존성을 세부항목으로 구성하였다. 평가 항목별로 5 등급의 평가 기준에 따라서 평가 점수를 부여하고 평가 총점을 산출하여 최종 연결성 평가 등급을 5 단계로 구분하였다. 현장평가를 위한 MS Access 기반 소프트웨어를 개발하여, 데이터 입력과 관리 및 평가 결과 산출과 비교를 편리하게 하였다. 개발된 제내지 하천환경 평가법을 청미천과 만경강에 적용하여 검증하였다. 개발된 평가법을 바탕으로 차단된 제내지 하천환경에서 연결성 회복에 따른 어류와 식생의 분포를 예측하는 수리생태 결합모델을 개발하였다. 먼저 차단된 제내지에서 연결 수로를 복원하여 유속, 수심 분포를 준이차 수리수문 모델로 예측하였다. 예측된 수리 환경에 따라서 지표어종의 서식처 적합도 지수 (HSI)를 이용하여 서식 분포 확률을 모의하였다. 또한 일반화가법모델 (GAM)을 이용하여 환경구배에 의한 우점식생의 분포를 예측하였다. 차단된 제내지 하천환경의 생태적 연계성 평가 기술을 기반으로 제방제거, 제방후퇴, 제방고 하강, 수문 및 연결수로 개선, 생물이동 저해 장벽 제거 등의 다양한 복원기술이 개발되어야 할 것으로 생각된다.

• The Journal of Traditional Korean Medicine
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• v.15 no.1
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• pp.113-127
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• 2006

Objectives: This study was produced to examine the effects of moxibustion that had been played important role to traditional oriental medical treatment on disease. Recently, it was reported that moxi-tar which is generated in the process of moxibustion as burning combustibles decreased nitric oxide(NO) and inducible NO synthase (iNOS) generation in cellular experiments. Methods: Carrageenan-induced arthritis rat model was used to test the effect of moxi-tar as a chronic pain model. Diluted moxi-tar was single injected in several acupoints or combined with electroacupuncture (l ms, 2 Hz, and 2 mA) into contralateral ST36 acupoint for 30 min to assess the synergic effects. After the treatment, behavioral tests measuring stepping force were periodically conducted during the next 12 hours. Endogenous NO and iNOS, cyclooxygenase-2 (COX-2), and c-Fos protein expression in the spinal cord were examined on a rat model of carrageenan-induced arthritis. Results : After the induction of arthritis, rats subsequently showed a reduced stepping force of the affected limb for at least the next 4 days. The reduced stepping force of the limb was presumably due to a painful knee, since oral injection of indomethacin produced temporary improvement of weight bearing. Maxi-tar produced significant improvement of stepping force of the hindlimb affected by the arthritis lasting at least 9 hours. The magnitude of this improvement was equivalent to that obtained after an oral injection of 3 mg/kg of indomethacin and this improvement of stepping force was interpreted as an analgesic effect. Maxi-tar produced the improvement of stepping force of the affected hindlimb in a dose-dependent manner. Both NO production and iNOS, COX-2 protein expression increased by arthritis were suppressed by maxi-tar. Moxi-tar on combination with electroacupuncture (EA) produced more powerful and longer lasting improvement of stepping force of the hindlimb affected by the arthritis than either moxi-tar or EA did. Conclusion : The present study suggest that maxi-tar produces a potent analgesic effect on the chronic knee arthritis pain model in the rat and that moxi-tar-induced analgesia modulate endogenous NO through the suppression of iNOS/COX-2 protein expression.

• Korean Journal of Soil Science and Fertilizer
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• v.48 no.5
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• pp.421-427
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• 2015

Angelica gigas Nakai is one of the most widely used herbal medicines and is known to have many pharmaceutical effects including an anti-oxidant, anti-cancer etc. This study was carried out to investigate an effect of fertilization on leaf yield, production of dry-matter and accumulation of pyranocurmarine compounds such as decursin (DE) and decursinol angelate (DA) in Angelica gigas Nakai. Effect of fertilization was determined from response surface regression equation composing of 2 by 3 factorial arrangement of urea, sodium dihydrogen phosphate and potassium chloride. Yield of leaf in Angelica gigas Nakai significantly increased until 100 days after transplanting. Production of leaf also tended to increase with increasing nitrogen fertilization. Model of regression equation showed that leaf production depended upon nitrogen ($Pr>{\mid}t{\mid}$ : 0.087, 0.256 and 0.079). Also, statistical results between nitrogen application level and production of dry-matter showed significant relationship (p<0.05) and contents of dry-matter was highest in 10 kg 10a-1 treatment on 24 Sep. Active compound isolated and purified from leaf and root of Angelica gigas Nakai was identified as DE and DA by gas chromatograph-mass spectrophotometry (GC-MS). Concentration of DA as prevalent compound in leaf was highest on 20 Aug. but decreased on 24 Sep. Amount of DE and DA accumulated in Angelica gigas Nakai significantly increased with growth stages and nitrogen level. The result of our investigation imply that nitrogen fertilization is important factor for production of leaf and accumulation of pyranocurmarine in Angelica gigas Nakai as a medicinal/food materials.

• The Korean Journal of Food And Nutrition
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• v.34 no.5
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• pp.477-486
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• 2021

To utilize Malus pruniforia Borkh. as a functional material, cold-water (CW), hot-water (HW), and 70% ethanol (EtOH) extracts were prepared, and their antioxidant and anti-inflammatory activities were compared. The antioxidant activity of the HW extract evaluated by ABTS and DPPH radical scavenging and FRAP activity was significantly effective. The total polyphenol content of the HW extract was also higher by 15.5±0.7 mg GAE/g extract compared to other extracts. The EtOH extract showed significantly decreased TNF-α (39.8%), IL-6 (65.5%), and NO (34.9%) levels in RAW 264.7 cells compared to the LPS-induced control group. The levels of IL-6 (21.1%) and IL-8 (19.3%) were significantly decreased by treatment of EtOH extract in HaCaT keratinocytes induced with TNF-α and IFN-γ. The UHPLC-MS results indicated that the EtOH extract might have chlorogenic acid and phlorizin as the major compounds. This was validated using HPLC-DAD, which showed that the EtOH extract had higher levels of chlorogenic acid and phlorizin (1,185±58 and 470±10 ㎍/g extract, respectively). In conclusion, the present study suggested that the anti-inflammatory activity of the EtOH extract was more effective than the CW and HW extracts, and chlorogenic acid and phlorizin could be used as indicator compounds and functional substances.

• Korean Journal of Breeding Science
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• v.42 no.6
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• pp.707-710
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• 2010

A new perilla cultivar, 'Bomnaeyeop 1 ho' was developed by, Kangwon National University in 2008. Its characteristics were investigated three times from 2006 to 2008 under optimal condition of cultivation. 'Bomnaeyeop 1 ho' can be characterized by dark green leaf color and tall plant height. This cultivar has more number of flower cluster and ear per cluster compare to 'Saeyeupsil' control. From result of GC/MS analysis, main compounds consist of perilla ketone, beta-caryophyllene and myristicin in 'Bomnaeyeop 1 ho' cultivar.