• Title/Summary/Keyword: 3DD

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Strains Difference of Ovulatory Response in Mice to Superovulation-treatment (과배란처리(過排卵處理)에 대(對)한 Mouse의 배란반응(排卵反應)의 계통차(系統差))

  • Jeon, Chang Ge;Ishijima, Yoshiro
    • Korean Journal of Agricultural Science
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    • v.5 no.2
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    • pp.77-79
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    • 1978
  • The Present study was examined the response of mice of 5 strains to superovulation treatment. Female mice of CF#1, C57BL/6, ICR, dd and CHN strains, aged 60 days were used. Superovulation was induced by the subcutaneous injection of 5 IU PMS and followed 48 hours later by the subcutaneous injection of 5 IU HeG. All females were killed 24 hours after RCG and then ova in the oviduct were counted under a microscope. The average number of ova ovulated in CF#1, C57BL/6, ICR, dd and CHN were 21.3, 17.9, 20.7, 21.0 and 20.5, respectively.

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Analysis of Carcass Characteristics in the 3rd Intron of Pig POU1F1 Gene (돼지의 POU1F1 Intron 3영역 유전자에 따른 도체특성 분석)

  • Kim, Gye-Woong;Yoo, Jae-Young
    • Journal of Animal Science and Technology
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    • v.51 no.4
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    • pp.283-288
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    • 2009
  • This study was carried out to compare Msp I polymorphisms in the 3rd intron of porcine gene encoding the pituitary-1 transcription factor (POU1F1) from 286 pigs (Landrace $\times$ Yorkshire $\times$ Duroc, LYD) and to determine the associations between its genotypes and carcass traits by using the PCR-RFLP technique. The frequency of the single nucleotide polymorphism (SNP) genotype DD (84.33%) was very higher than that of CC genotype (0.75%). Allelic frequencies for C and D were 0.082 and 0.918, respectively. Each population followed the Hardy-Weinberg equilibrium. Meat colours of Hunter $L^*$ values and visual colour according to two genotypes were all significantly different. However, no significant difference in crossbred (LYD) was found between CD and DD genotypes for other traits. Therefore, this suggests that POU1F1 may be a major gene or marker for carcass traits.

Evaluation of Pheromone Lure of Grapholita molesta (Lpidoptera: Torticidae) and Forecasting Its Phenological Events in Suwon (복숭아순나방 성페로몬 미끼 평가 및 수원지역에서 주요 발생시기 예찰)

  • Kim Dong Soon;Boo Kyung Saeng;Jeon Heung Yong
    • Korean journal of applied entomology
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    • v.43 no.4 s.137
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    • pp.281-289
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    • 2004
  • The sex pheromone blend (28-12AC : E8-12AC : Z8-12OH = 95 : 5 : 1) of oriental fruit moth, Grapholita molesta (Busck), was evaluated with reference to its male attractivity at different dosage and lure longevity of 1.0 mg in a field condition. Also, degree-days (DD) were calculated up to major phenological events of G. molesta using seasonal adult flights monitored by pheromone traps and egg population densities in early season in Suwon peach orchards. In the range of 0.1-4.0 mg dosage examined, G. molesta males caught in pheromone trap decreased with increasing total pheromone doses. The highest number of G. molesta males were attracted in traps baited with 0.1 mg-lure, and there were no significantly differences among 0.5 to 4.0 mg-lure. In longevity test with a 1.0 mg-lure, there was no difference in mean numbers of G. molesta males caught between traps with fresh-baited lures every 20d and field-lasted lures up to ${\approx}50d$ after trap installation, but thereafter more G. molesta males were attracted in the field-lasted lures than in the fresh-baited lures. Accumulated degree-days (DD) from January 1 to the first adult emergence (biofix) were 39DD at a lower threshold temperature $8.1^{\circ}C$. Degree-days from the biofix up to the 1st adult peak through 4th peak were 98DD, 620DD, 1233DD, and 1916DD, respectively. Required degree-days from the 1st adult peak to the 1st egg peak were 130DD, while the 2nd egg peak timing was simultaneous with the 2nd adult peak. Further, management strategies of G. molesta were discussed in peach orchards.

Two-step a priori SNR Estimation in the Log-mel Domain Considering Phase Information (위상 정보를 고려한 로그멜 영역에서의 2단계 선험 SNR 추정)

  • Lee, Yun-Kyung;Kwon, Oh-Wook
    • Phonetics and Speech Sciences
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    • v.3 no.1
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    • pp.87-94
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    • 2011
  • The decision directed (DD) approach is widely used to determine a priori SNR from noisy speech signals. In conventional speech enhancement systems with a DD approach, a priori SNR is estimated by using only the magnitude components and consequently follows a posteriori SNR with one frame delay. We propose a phase-dependent two-step a priori SNR estimator based on the minimum mean square error (MMSE) in the log-mel spectral domain so that we can consider both magnitude and phase information, and it can overcome the performance degradation caused by one frame delay. From the experimental results, the proposed estimator is shown to improve the output SNR of enhanced speech signals by 2.3 dB compared to the conventional DD approach-based system.

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Three-dimensional dose reconstruction-based pretreatment dosimetric verification in volumetric modulated arc therapy for prostate cancer

  • Jeong, Yuri;Oh, Jeong Geun;Kang, Jeong Ku;Moon, Sun Rock;Lee, Kang Kyoo
    • Radiation Oncology Journal
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    • v.38 no.1
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    • pp.60-67
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    • 2020
  • Purpose: We performed three-dimensional (3D) dose reconstruction-based pretreatment verification to evaluate gamma analysis acceptance criteria in volumetric modulated arc therapy (VMAT) for prostate cancer. Materials and Methods: Pretreatment verification for 28 VMAT plans for prostate cancer was performed using the COMPASS system with a dolphin detector. The 3D reconstructed dose distribution of the treatment planning system calculation (TC) was compared with that of COMPASS independent calculation (CC) and COMPASS reconstruction from the dolphin detector measurement (CR). Gamma results (gamma failure rate and average gamma value [GFR and γAvg]) and dose-volume histogram (DVH) deviations, 98%, 2% and mean dose-volume difference (DD98%, DD2% and DDmean), were evaluated. Gamma analyses were performed with two acceptance criteria, 2%/2 mm and 3%/3 mm. Results: The GFR in 2%/2 mm criteria were less than 8%, and those in 3%/3 mm criteria were less than 1% for all structures in comparisons between TC, CC, and CR. In the comparison between TC and CR, GFR and γAvg in 2%/2 mm criteria were significantly higher than those in 3%/3 mm criteria. The DVH deviations were within 2%, except for DDmean (%) for rectum and bladder. Conclusions: The 3%/3 mm criteria were not strict enough to identify any discrepancies between planned and measured doses, and DVH deviations were less than 2% in most parameters. Therefore, gamma criteria of 2%/2 mm and DVH related parameters could be a useful tool for pretreatment verification for VMAT in prostate cancer.

Outcome of Conservative Treatment for Patients with Disc Displacement of Temporomandibular Joint (측두하악관절 원판변위 환자의 보존적 치료결과)

  • Kim, Kyung-Hee;Kim, Ik-Hwan;Ko, Myung-Yun;Ahn, Yong-Woo
    • Journal of Oral Medicine and Pain
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    • v.32 no.3
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    • pp.305-318
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    • 2007
  • To evaluate the treatment outcome after conservative treatment in patients with TMJ disc displacement which is the most common temporomandibular joint arthropathy, the subjects were chosen among the patients who presented to the Department of Oral Medicine of Pusan National University Hospital, diagnosed as TMDs and treated with conservative methods from 1994 to 2006 for 13 years. 88 patients with diagnosis of DD/cR and 60 patients with diagnosis of DD/sR were selected as the experimental group and 74 patients with diagnosis of masticatory muscle disorder (MMD) were selected as the control group. Subjective symptoms and clinical findings were investigated to evaluate and compare the subjects' status at the first visit and the last visit. The results were as follows; 1. Pain, noise, LOM and MCO measurements of DD/cR, DD/sR and MMD groups were markedly improved after conservative treatments including behavior therapy, physical therapy, medication and splint therapy. 2. At the first visit, high score of pain in MMD group, high score of noise and large MCO measurement in DD/cR group and high LOM score in DD/sR group were observed. At the last visit, high score of noise and increased MCO measurement in DD/cR group and high score of pain and LOM in DD/sR group were observed. 3. Among the patients who complained joint sound at their first visit, about 60% showed complete loss of joint sound after conservative treatment 4. DD/cR and DD/sR groups showed satisfactory outcomes after conservative treatments such as behavior therapy, physical therapy, medication and splint therapy while MMD group showed similar treatment outcome irrespective of the treatment modality used. 5. There was no difference in treatment outcomes after conservative treatments when the subjects were classified and compared according to gender, age group and chronicity. 6. MMD showed satisfactory prognosis in 10 treatments in less than 6 months while DD showed favorable prognosis in 10-20 treatments for 6 months to 2 years.

Interaction Characteristics of Nucleoside Analogues with Human Organic Anion Transporter 1 and 3

  • Choi, Jun-Shik;Cheon, Eun-Pa;Han, Hyo-Kyung
    • Journal of Pharmaceutical Investigation
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    • v.36 no.4
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    • pp.283-286
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    • 2006
  • The present study aimed to investigate the interaction of nucleoside analogs with human organic anion transporter 1 and 3(hOAT1 and hOAT3) that play a primary role in the tubular uptake of endogenous and exogenous organic anions in the kidney. The interactions of ddC, ara-C, ara-A and ara-U with hOAT1 and hOAT3 were examined using MDCK cells stably overexpressing hOAT1 or hOAT3. Among the tested drugs, ddC showed the highest affinity to hOAT1 with $IC_{50}$ values of 5.2 mM, while ara-A, ara-C and ara-U weakly inhibited the cellular uptake of $[^3H]-PAH$ in MDCK-hOAT1 cells at 1 mM. In contrast, all the tested drugs did not have any inhibition effect on the cellular uptake of $[^3H]-estrone$ sulfate in MDCK-hOAT3 cells over the drug concentration of 0.01-2 mM, implying that they might not interact with hOAT3. Taken all together, the present study suggests that hOAT1 could weakly interact with nucleoside analogues such as ddC, ara-C, ara-A and ara-U but the interaction with hOAT3 during the urinary excretion of these nucleoside analogues may be negligible in the kidney.

Microwave Radiation-Assisted Chitin Deacetylation: Optimization by Response Surface Methodology (RSM)

  • Iqmal Tahir;Karna Wijaya;Mudasir;Dita Krismayanti;Aldino Javier Saviola;Roswanira Abdul Wahab;Amalia Kurnia Amin;Wahyu Dita Saputri;Remi Ayu Pratika
    • Korean Journal of Materials Research
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    • v.34 no.2
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    • pp.85-94
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    • 2024
  • The optimization of deacetylation process parameters for producing chitosan from isolated chitin shrimp shell waste was investigated using response surface methodology with central composite design (RSM-CCD). Three independent variables viz, NaOH concentration (X1), radiation power (X2), and reaction time (X3) were examined to determine their respective effects on the degree of deacetylation (DD). The DD of chitosan was also calculated using the baseline approach of the Fourier Transform Infrared (FTIR) spectra of the yields. RSM-CCD analysis showed that the optimal chitosan DD value of 96.45 % was obtained at an optimized condition of 63.41 % (w/v) NaOH concentration, 227.28 W radiation power, and 3.34 min deacetylation reaction. The DD was strongly controlled by NaOH concentration, irradiation power, and reaction duration. The coefficients of correlation were 0.257, 0.680, and 0.390, respectively. Because the procedure used microwave radiation absorption, radiation power had a substantial correlation of 0.600~0.800 compared to the two low variables, which were 0.200~0.400. This independently predicted robust quadratic model interaction has been validated for predicting the DD of chitin.

Evaluation of the marginal and internal fit of a single crown fabricated based on a three-dimensional printed model

  • Jang, Yeon;Sim, Ji-Young;Park, Jong-Kyoung;Kim, Woong-Chul;Kim, Hae-Young;Kim, Ji-Hwan
    • The Journal of Advanced Prosthodontics
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    • v.10 no.5
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    • pp.367-373
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    • 2018
  • PURPOSE. To evaluate the fit of a crown produced based on a 3D printed model and to investigate its clinical applicability. MATERIALS AND METHODS. A master die was fabricated with epoxy. Stone dies were fabricated from conventional impressions (Conventional stone die group: CS, n=10). Digital virtual dies were fabricated by making digital impressions (Digital Virtual die group: VD, n=10). 3D data obtained from the digital impression was used to fabricate 3D printed models (DLP die group: DD, n=10, PolyJet die group: PD, n=10). A total of 40 crowns were fabricated with a milling machine, based on CS, VD, DD and PD. The inner surface of all crowns was superimposed with the master die files by the "Best-fit alignment" method using the analysis software. One-way and 2-way ANOVA were performed to identify significant differences among the groups and areas and their interactive effects (${\alpha}=.05$). Tukey's HSD was used for post-hoc analysis. RESULTS. One-way ANOVA results revealed a significantly higher RMS value in the 3D printed models (DD and PD) than in the CS and DV. The RMS values of PD were the largest among the four groups. Statistically significant differences among groups (P<.001) and between areas (P<.001) were further revealed by 2-way ANOVA. CONCLUSION. Although the fit of crowns fabricated based on the 3D printed models (DD and PD) was inferior to that of crowns prepared with CS and DV, the values of all four groups were within the clinically acceptable range (<$120{\mu}m$).

Design of Carrier Recovery Circuit for High-Order QAM - Part I : Design and Analysis of Phase Detector with Large Frequency Acquisition Range (High-Order QAM에 적합한 반송파 동기회로 설계 - I부. 넓은 주파수 포착범위를 가지는 위상검출기 설계 및 분석)

  • Kim, Ki-Yun;Cho, Byung-Hak;Choi, Hyung-Jin
    • Journal of the Institute of Electronics Engineers of Korea TC
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    • v.38 no.4
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    • pp.11-17
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    • 2001
  • In this paper, we propose a polarity decision carrier recovery algorithm for high order QAM(Quadrature Amplitude Modulation), which has robust and large frequency acquisition performance in the high order QAM modem. The proposed polarity decision PD(Phase Detector) output and its variance characteristic are mathematically derived and the simulation results are compared with conventional DD(Decision-Directed) method. While the conventional DD algorithm has linear range of $3.5^{\circ}{\sim}3.5^{\circ}$, the proposed polarity decision PD algorithm has linear range as large as $-36^{\circ}{\sim}36^{\circ}$ at ${\gamma}-17.9$. The conventional DD algorithm can only acquire offsets less than ${\pm}10\;KHz$ in the case of the 256 QAM while an analog front-end circuit generally can reduce the carrier-frequency offset down to only ${\pm}100\;KHz$. Thus, in this case additional AFC or phase detection circuit for carrier recovery is required. But by adopting the proposed polarity decision algorithm, we can find the system can acquire up to ${\pm}300\;KHz$at SNR = 30dB without aided circuit.

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