• Economic and Environmental Geology
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• v.17 no.1
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• pp.49-55
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• 1984

This paper describes three-dimensional (3-D) standard curves for conductive dipping buried bodies in induced polarization (IP) method. Dipole-dipole IP responses for the dipping bodies are calculated by the numerical modeling technique using an integral equation solution. Dip angles of the bodies are 0, 20, 45, 70 and 90 degrees, respectively. The horizontal (0-degree dip) and vertical (90-degree dip) bodies produce symmetrical patterns of IP responses. The dipping bodies of 20, 45 and 70 degrees, however, produce asymmertical patterns, with the highest IP contours dipping in the direction opposite to the bodies in pseudo-sections. The most remarkable asymmetrical pattern appears in the model of 20-degree dip. It is difficult to distinguish the body of 70-degree dip from that of 90-degree dip on the basis of dipole-dipole IP data. The IP pattern in pseudo-sections varies when the line moves away from the center of the body along strike, with the anomaly deeper and smaller in amplitude. IP maps seem to be more useful than IP pseudo-sections in predicting the location of target.

• The KIPS Transactions:PartB
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• v.13B no.2 s.105
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• pp.187-196
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• 2006

In 3D animation most people adjust the moving motion of their characters on various terrains by using motion data acquired with the motion capture equipment. The motion data can be used to present real human motions naturally, but the data must be captured again to apply to the different terrains from those given at acquiring mode. In addition, there would be a difficulty when applying the data to other characters, in that case the motion data must be captured newly or the existing motion data must be heavily edited manually. In this paper we propose a unified method to generate human motions of walking and running for various terrains such as flat plane, inclined plane, stairway and irregular face. With these methods we are able to generate human motions controlled by the parameters : body height, moving speed, stride, etc. In the proposed methods, the positions and angles of joint can be calculated by using inverse kinematics, and we calculate the trajectory of the swing leg and pelvis according to the cubic spline. With these methods we were presented moving motions using a model of a human body.

• Korean Journal of Applied Biomechanics
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• v.32 no.1
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• pp.17-23
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• 2022

Objective: The aim of this study was to investigate the effect Tiger-step walking on the movement of the lower extremities during walking. Method: Twenty healthy male adults who had no experience of musculoskeletal injuries on lower extremities in the last six months (age: 26.85 ± 3.28 yrs, height: 174.6 ± 3.72 cm, weight: 73.65 ± 7.48 kg) participated in this study. In this study, 7-segments whole-body model (pelvis, both side of thigh, shank and foot) was used and 29 reflective markers and cluster were attached to the body to identify the segments during the gait. A 3-dimensional motion analysis with 8 infrared cameras and 7 channeled EMG was performed to find the effect of tigerstep on uphill walking. To verify the tigerstep effect, a one-way ANOVA with a repeated measure was used and the statistical significance level was set at α=.05. Results: Firstly, Both Tiger-steps showed a significant increase in stance time and stride length compared with normal walking (p<.05), while both Tiger-steps shown significantly reduced cadence compared to normal walking (p<.05). Secondly, both Tiger-steps revealed significantly increased in hip and ankle joint range of motion compared with normal walking at all planes (p<.05). On the other hand, both Tiger-steps showed significantly increased knee joint range of motion compared with normal walking at the frontal and transverse planes (p<.05). Lastly, Gluteus maximus, biceps femoris, medial gastrocnemius, tibialis anterior of both tiger-step revealed significantly increased muscle activation compared with normal walking in gait cycle and stance phase (p<.05). On the other hand, in swing phase, the muscle activity of the vastus medialis, biceps femoris, tibialis anterior of both tiger-step significantly increased compared with those of normal walking (p <.05). Conclusion: As a result of this study, Tiger step revealed increased in 3d range of motion of lower extremity joints as well as the muscle activities associated with range of motion. These findings were evaluated as an increase in stride length, which is essential for efficient walking. Therefore, the finding of this study prove the effectiveness of the tiger step when walking uphill, and it is thought that it will help develop a more efficient tiger step in the future, which has not been scientifically proven.

• Journal of the Korean Society of Clothing and Textiles
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• v.32 no.12
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• pp.1825-1836
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• 2008

Many applications in computer graphics require complex and highly detailed models. However it is often desirable to use approximations in place of excessively detailed models in order to control the processing time. Thus, we aim to develop a notion of optimal matrix to simplify surface which can rapidly obtain the high quality 2D patterns flattening 3D surface as follows. Firstly, two 3D bodies are modeled based on existing Size Korea data. Secondly, each model is divided by shell and block for its pattern draft. Thirdly, each block is flattened by grid and bridge method. Finally, we selected the optimal matrix and demonstrated the efficiency and quality of the proposed method. This proposed approach accommodates surfaces with darts, which are commonly used in the clothing industry to reduce the deformation of surface forming and flattening. The resulting optimal matrix could be an initiation of standardization for pattern flattening. It is expected that this method could facilitate much better approximation in both efficiency and precision.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.11
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• pp.5753-5757
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• 2012

Apoptosis, also known as cell suicide or programmed cell death, removes unwanted and genetically damaged cells from the body. Evasion of apoptosis is one of the major characteristic features of rapidly proliferating tumor cells. Chemopreventive agents inhibit or suppress tumor formation through apoptotic induction in target tissues. The aim of the present study was to investigate the pro-apoptotic potential of lupeol during 7,12-dimethylbenz(a) anthracene (DMBA) induced hamster buccal pouch carcinogenesis. Topical application of 0.5% DMBA three times a week for 14 weeks in the buccal pouches of golden Syrian hamsters resulted in oral squamous cell carcinoma. The expression pattern of apoptotic markers was analyzed using immunohistochemistry (p53, Bcl-2, Bax) and ELISA reader (caspase 3 and 9). In the present study, 100% tumor formation with defects in apoptotic markerexpression pattern was noticed in hamsters treated with DMBA alone. Oral administration of lupeol at a dose of 50mg/kg bw completely prevented the formation oral tumors as well as decreased the expression p53 and Bcl-2, while increasing the expression of Bax and the activities of caspase 3 and 9. The present study thus indicated that lupeol might inhibit DMBA-induced oral tumor formation through its pro-apoptotic potential in golden Syrian hamsters.

• The Journal of Korean Society of Virology
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• v.29 no.3
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• pp.165-174
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• 1999

To investigate viral pathogenesis and in vivo efficacy of acyclovir (ACV) in mouse HSV-1 encephalitis models, female BALB/c mice aged 5 weeks were inoculated with strain F either intranasally (IN) or intracerebrally (IC). ACV-treatment by intraperitomeal injection with 0, 5, 10 and 25 mg/kg b.i.d. for 6 days was commenced 1 h after infection. Body weight and signs of clinical disease were noted daily up to 2 weeks. $ED_{50}$ of ACV in IN infection was <5 mg/kg and 14.1 mg/kg in IC infection. Tissues of central nervous system were collected from 2 mice per group everyday up to 5 day p.i. and the virus titers were measured. In IN infection model, high titers in eyes and trigeminal nerves were observed. ACV-treatment showed significant reduction of the titers in all the isolated. In IC infection model, cerebrum, cerebellum and brain stem showed high virus titers. ACV-treatment showed less significant reduction of virus titers than that in IN infection model. Reactivation of explanted trigeminal nerves from mice 30 day p.i. was monitored. In all of ACV treated mice reactivation was observed, i.e. even the highest dose of ACV did not inhibit the establishment of viral latency.

• Proceedings of the KSME Conference
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• 2000.11b
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• pp.371-376
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• 2000

In this study, the computational method is presented to simulate the hemodynamics of the patients after the Fontan procedure. The short-term feedback control models are implemented to assess the hemodynamic responses of the patients exposed to the stresses such as gravitational effect or hemorrhage. To construct the base line of the Fontan model, we assume an increase in venous tone, in heart rates, and in systemic resistance that are based on the clinical observations. For the verification of the present method we simulate the LBNP (lower body negative pressure) test for the normal and the Fontan model and we compare these with experimental data. Computational results show that the diastolic ABP(arterial blood pressure) increases but the systolic ABP decreases during LBNP. The increase in heart rate is due to the control system activated by the decreased mean ABP and CVP(central venous pressure). In case of the Fontan model, the increased venous tone is the reason of the diminished CVP change during LBNP. We also simulate 20% hemorrhage stress to the patient after the Fontan procedure and these results are compared with the experimental and the existing computational one. Computational results on the hemodynamics of patients after the Fontan procedure show that the mean ABP and cardiac output decrease. Heart rate and systemic resistance increase to compensate for the decrease in ABP. The sensitivity analysis according to the conduit resistance is also presented to delineate the effects of the local blood flow resistance. The cardiac output decreases according to the increase of the conduit resistance. The 50% increase in the conduit resistance causes about 3% decrease of cardiac output.

• Journal of the Korean housing association
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• v.20 no.1
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• pp.59-70
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• 2009

The purpose of the study is to suggest the amount of space for each behavior according to the classification of behavior in the housing to plan the optimal floor space of the elderly housing. The method for calculating space for behavior begins with classifying behaviors, identifying them and then taking pictures of the model of elderly people who reproduce each behavior. Based on the pictures, body parts which are necessary for each behavior are assembled and the formula for behavioral space is created. The space for behavior is produced considering the body dimensions of Korean elderly in their sixty's as well as the furniture size and the psychological distance between people. 3D modeling is used to verify the result. Human behaviors can be classified into individual-related, housework-related, family-related, reception-related and other behaviors. These five behaviors are subdivided into more specific behaviors. The area for each specific behavior is calculated with the anthropometric data of the elderly, preferred furniture dimension and psychological area. As a result the required area for specific behaviors is as follows: the behavior of sleeping in a bed needs $4.3m^2$; the behavior of changing clothes on a chair, $1.7m^2$; the behavior of watching TV on the floor $1.3m^2$, the behavior of working and reading using a desk, $2.1m^2$, the behavior of exercise, $2.5m^2$; the behavior of showering on a chair, $1.3m^2$ and showering using a wheelchair, $1.9m^2$; the behavior of toileting using a wheelchair, $2.3m^2$; the behavior of washing up using a wheelchair, $1.9m^2$; the behavior of eating using a table for four persons, $4.4m^2$; the behavior of cooking and washing dishes, $0.9m^2$ per counter-top; the behavior of washing clothes using a washing machine, $0.9m^2$; the behavior of ironing on the floor $1.4m^2$; the behavior of reception(three persons) on the floor considering personal space, $4.0m^2$; the behavior of taking on and off shoes on a chair, $1.3m^2$. The result of the study is utilized as quantitative data to calculate optimal floor space for elderly housing. In addition, qualitative data such as characteristics of housing preference, spacial usage and storage capacity are necessary to produce the floor space which can provide convenient and safe living environment.

• The Korean Journal of Mycology
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• v.41 no.3
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• pp.192-196
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• 2013

Fungal development is largely affected by many environmental factors. In a model filamentous fungus Aspergillus nidulans, asexual development is promoted by exposure of light, presence of salt and non-fermentable sugars. In other hand, sexual development is largely induced by absence of light, fermentable sugars and hypoxic condition. Also, some important genes including veA and nsdD play positive roles in activating sexual development. Here, we reported that the effect of high concentration of $CO_2$ on developmental decision in A. nidulans. When wild-type $veA^+$ strain was cultured in normal condition, sexual and asexual development occurred in balanced manner. However, high concentration of $CO_2$ (~5%) strongly activated sexual development and inhibited asexual development. Furthermore, this $CO_2$ effect was controlled by the veA or nsdD gene. High $CO_2$ culture of $veA^-$ or $nsdD^-$ mutant didn't activate sexual development, suggesting that the activation of sexual development induced by high $CO_2$ cannot overcome the genetic requirement of sexual development such as veA or nsdD. Since 5% $CO_2$ is an important condition for human pathogenic fungi for surviving and adapting in human body, this developmental pattern of A. nidulans affected by $CO_2$ concentration may provide interesting clues for comparative study with human fungal pathogens including Aspergillus fumigatus.

• Journal of Animal Science and Technology
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• v.45 no.4
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• pp.509-516
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• 2003

Growth curves were estimated for 1083 female Korean cattle raised in Daekwanryeong branch, National Livestock Research Institute (NLRI). Comparisons were made among various growth curve models for goodness of fit for the growth of the cows. Estimated growth curve functions were $W_t=370.2e^{-2.208e^{-0.00327t}$ for Gompertz model, for von Bertalanffy model, and $W_t=341.2(1+5.652e^{-0.00524t})^{-1}$ for Logistic model. Ages at inflection estimated from Gompertz model, von Bertalanffy model and Logistic model were 242.2 days, 191.5 days, and 330.5 days respectively, body weight at inflection were 136kg, 115kg, and 170kg, and daily gain at inflection were 0.445kg, 0.451kg, and 0.446kg. The predicted weights by ages from Gompertz model, von Bertalanffy model, and Logistic model were onsistently overestimated at birth weight and underestimated at 36 month weight. The von Bertalanffy model which had a variable point of inflection fit the data best.