• Bulletin of the Korean Chemical Society
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• 제27권2호
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• pp.273-276
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• 2006

Three dimensional quantitative structure-activity relationship studies for a series of isatin derivatives as a nonpeptidyl caspase-3 enzyme inhibitor were investigated using comparative molecular field analysis (CoMFA) and comparative molecular similarity indices analysis (CoMSIA). The first approach of non-peptidyl small molecules by 3D QSAR may be useful in guiding further development of potent caspase-3 inhibitors.

• 한국생산제조학회지
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• 제26권1호
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• pp.6-12
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• 2017

In a large 3D printer when the cooler, which cools the filament, acts in one direction, the area directly exposed to the cooling is cooled to the proper temperature. However, the cooling effect on the opposite area is relatively less. It was found in experiments that filaments with a thickness of over 2 mm exhibit the cooling problem in one directional cooling. Consequently, cooling was performed to prevent the flow-down and to produce firm support leading to an improvement in product quality in extrusion. Further, the lay-up of a 3D printer with five guides combined with a duct was achieved. Analysis showed that the improvement in the cooling effect enables stable extrusion and lay-up and thus, reduces fabrication time.

• 한국디자인학회:학술대회논문집
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• 한국디자인학회 2004년도 추계 학술발표대회 논문집
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• pp.194-195
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• 2004

• 구강회복응용과학지
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• 제32권2호
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• pp.141-148
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• 2016

Computer-aided technology는 최근 치과 치료의 흐름이다. DENTCA$^{TM}$ CAD/CAM denture (DENTCA Inc.)는 상용화된 computer-aided design/computer-aided manufacturing (CAD/CAM) 의치 시스템 중 하나로, 한 번의 내원을 통해 의치 제작에 필요한 환자의 모든 정보를 획득하여, 이 정보를 컴퓨터에 저장하고 3D 프린팅을 통해 두 번째 내원 시에 의치 장착을 목표로 한다. 현재까지 여러 증례들은 총의치 제작에 대한 CAD/CAM system의 임상적 적용을 시험해 보았다. 본 증례는 두 명의 환자에서 DENTCA system을 이용한 의치와 전통적인 방법을 이용한 의치를 동시에 제작하여 DENTCA system의 효용성과 한계점을 고찰하였다.

• 대한치과보철학회지
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• 제55권4호
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• pp.436-443
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• 2017

과거의 computer-aided design/computer-aided manufacturing (CAD/CAM) 기술 형태는 사용자가 한 제조사의 구성요소만 사용해야 하는 폐쇄적인 시스템이었다면, 현재는 여러 제조사의 구성요소 중 사용자가 필요에 맞는 구성요소를 선택해서 사용할 수 있는 유연성을 가진 개방적인 시스템 형태로 변화하였다. 치과재료와 보철물 제작 기술의 발전에도 불구하고 의치 제작은 지난 100년 가까이 전통적인 제작방식을 따랐다. 하지만 최근 들어 기존 의치 제작의 단점을 보완하고자 CAD/CAM 제작 의치에 관한 연구가 활발히 이루어지고 있으며, 밀링이나 3D 프린팅을 이용해 상용화된 형태의 CAD/CAM 제작 의치가 이미 임상에서 쓰이고 있다. 본 증례는 3D face scan을 활용한 CAD/CAM 의치 제작의 가능성을 확인하고, CAD/CAM과 전통적인 방법으로 제작한 의치를 비교한 결과에 대해 보고하고자 한다.

• 한국정밀공학회지
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• 제31권12호
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• pp.1085-1091
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• 2014

Recently, 3D printing has received increasing attention due to its boundless potentials. Because 3D printing starts from 3D geometry information, computer-aided design (CAD) is an essential technology to build 3D geometry data. These days, education of 3D CAD for engineering students has been changed from the theoretical lecture to practical design training using commercial CAD software. As a result, open-ended design projects have replaced the traditional theoretical examinations to evaluate students' outcomes. However, such design projects are not enough to evaluate students' outcomes because their results are expressed in two-dimensional ways. In this paper, applications of 3D printing in engineering design education are discussed by describing the procedure and outcomes of design projects. It was found that the use of 3D printing could improve students' outcomes by fabricating real physical models out of their designs.

• 한국생산제조학회지
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• 제24권2호
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• pp.148-154
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• 2015

Computer aided process planning (CAPP) keeps an important role between the design and manufacturing engineering processes. A CAPP system is a digital link between a computer aided design (CAD) model and manufacturing instructions. CAPP have been researched and applied in manufacturing filed, however, one manufacturing area where CAPP has not been extensively researched is rapid prototyping (RP). RP is a technique for creating directly a three dimensional CAD data into a physical prototype. RP enables to build physical models automatically and to use to reduce the time for the product development cycle as well as to improve the final quality of the designed product. Three-dimensional (3D) printing is one kind of RP that creates three-dimensional objects from CAD models. The paper presents a computer aided process planning system for printing medical products. 3D printing has been used to solve complex medical problems such as surgical instruments, bioengineered products, medical implants, and surgical guides.

• The Journal of Advanced Prosthodontics
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• 제10권3호
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• pp.245-251
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• 2018

PURPOSE. To evaluate the accuracy of a model made using the computer-aided design/computer-aided manufacture (CAD/CAM) milling method and 3D printing method and to confirm its applicability as a work model for dental prosthesis production. MATERIALS AND METHODS. First, a natural tooth model (ANA-4, Frasaco, Germany) was scanned using an oral scanner. The obtained scan data were then used as a CAD reference model (CRM), to produce a total of 10 models each, either using the milling method or the 3D printing method. The 20 models were then scanned using a desktop scanner and the CAD test model was formed. The accuracy of the two groups was compared using dedicated software to calculate the root mean square (RMS) value after superimposing CRM and CAD test model (CTM). RESULTS. The RMS value ($152{\pm}52{\mu}m$) of the model manufactured by the milling method was significantly higher than the RMS value ($52{\pm}9{\mu}m$) of the model produced by the 3D printing method. CONCLUSION. The accuracy of the 3D printing method is superior to that of the milling method, but at present, both methods are limited in their application as a work model for prosthesis manufacture.

• 재활복지공학회논문지
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• 제9권2호
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• pp.145-151
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• 2015

본 연구에서는 3D 스캐닝에서 획득한 이미지 정보를 바탕으로 3차원 그래픽 제품설계와 3D 프린팅 기술을 적용한 보조기 제작방법을 제시하였다. 뇌성마비 환자를 대상으로 4가지 종류의 보조기를 기존의 수작업이 아닌 전산화된 작업 기술을 적용하여 제작해봄으로써 방법과 절차에 대한 기준을 마련하고, 이 기술이 임상적으로 사용 가능한지 여부에 대해 확인했다. 보조기 사용 시 환자만족도와 보조기 제작시간, 인장강도 등의 비교를 통하여 정량적, 정성적으로 제작방법의 적용 가능성을 검증한 결과 기존의 열가소성 수지가 표출했던 문제를 보완하고 대체가능한 방법이 될 가능성이 있음을 확인하였다.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제37권
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• pp.44.1-44.6
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• 2015

Background: The present study introduces the design and fabrication of a simple surgical guide with which to perform genioplasty. Methods: A three-dimensional reconstruction of the patient's cranio-maxilla region was built, with a dentofacial skeletal model, then derived from CT DICOM data. A surgical simulation was performed on the maxilla and mandible, using three-dimensional cephalometry. We then simulated a full genioplasty, in silico, using the three-dimensional (3D) model of the mandible, according to the final surgical treatment plan. The simulation allowed us to design a surgical guide for genioplasty, which was then computer-rendered and 3D-printed. The manufactured surgical device was ultimately used in an actual genioplasty to guide the osteotomy and to move the cut bone segment to the intended location. Results: We successfully performed the osteotomy, as planned during a genioplasty, using the computer-aided design and computer-aided manufacturing (CAD/CAM) surgical guide that we initially designed and tested using simulated surgery. Conclusions: The surgical guide that we developed proved to be a simple and practical tool with which to assist the surgeon in accurately cutting and removing bone segments, during a genioplasty surgery, as preoperatively planned during 3D surgical simulations.