• Bulletin of the Korean Chemical Society
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• v.27 no.2
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• pp.273-276
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• 2006

Three dimensional quantitative structure-activity relationship studies for a series of isatin derivatives as a nonpeptidyl caspase-3 enzyme inhibitor were investigated using comparative molecular field analysis (CoMFA) and comparative molecular similarity indices analysis (CoMSIA). The first approach of non-peptidyl small molecules by 3D QSAR may be useful in guiding further development of potent caspase-3 inhibitors.

• Journal of the Korean Society of Manufacturing Technology Engineers
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• v.26 no.1
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• pp.6-12
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• 2017

In a large 3D printer when the cooler, which cools the filament, acts in one direction, the area directly exposed to the cooling is cooled to the proper temperature. However, the cooling effect on the opposite area is relatively less. It was found in experiments that filaments with a thickness of over 2 mm exhibit the cooling problem in one directional cooling. Consequently, cooling was performed to prevent the flow-down and to produce firm support leading to an improvement in product quality in extrusion. Further, the lay-up of a 3D printer with five guides combined with a duct was achieved. Analysis showed that the improvement in the cooling effect enables stable extrusion and lay-up and thus, reduces fabrication time.

• Proceedings of the Korea Society of Design Studies Conference
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• 2004.10a
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• pp.194-195
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• 2004

• Journal of Dental Rehabilitation and Applied Science
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• v.32 no.2
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• pp.141-148
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• 2016

Recently computer-aided technology has been widely used in dentistry. DENTCA$^{TM}$ CAD/CAM denture system (DENTCA Inc.), one of CAD/CAM systems for fabricating complete denture, tries to collect and store all of a patient's information at the first visit. This system aims to deliver denture at the second visit through utilizing the CAD/CAM software to access the stored data for designing the 3D denture model. The 3 dimensional (3D) denture will then be fabricated with 3D printer. Many case reports have evaluated clinical application of CAD/CAM system for fabricating complete dentures. This case report is about fabricating of complete dentures using DENTCA system and conventional method in same patient. With two cases, usefulness and limitation of DENTCA system could be evaluated.

• The Journal of Korean Academy of Prosthodontics
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• v.55 no.4
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• pp.436-443
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• 2017

In the past, computer-aided design / computer-aided manufacturing (CAD/CAM) technology was the closed system that users had to use the components of only one manufacturer. At present, it has changed to the open system with the flexibility to select and use the components of various manufacturers' components according to their needs. Despite the development of dental materials and prostheses manufacturing methods, denture manufacturing has followed conventional manufacturing methods for nearly 100 years. However, studies on CAD/CAM fabricated denture have been recently carried out to overcome the disadvantages of conventional denture manufacturing. Some commercialized products using milling or 3D printing have already been applied clinically. This case report confirms the possibility of CAD/CAM dentures using 3D face scan and compared them to conventionally fabricated dentures.

• Journal of the Korean Society for Precision Engineering
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• v.31 no.12
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• pp.1085-1091
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• 2014

Recently, 3D printing has received increasing attention due to its boundless potentials. Because 3D printing starts from 3D geometry information, computer-aided design (CAD) is an essential technology to build 3D geometry data. These days, education of 3D CAD for engineering students has been changed from the theoretical lecture to practical design training using commercial CAD software. As a result, open-ended design projects have replaced the traditional theoretical examinations to evaluate students' outcomes. However, such design projects are not enough to evaluate students' outcomes because their results are expressed in two-dimensional ways. In this paper, applications of 3D printing in engineering design education are discussed by describing the procedure and outcomes of design projects. It was found that the use of 3D printing could improve students' outcomes by fabricating real physical models out of their designs.

• Journal of the Korean Society of Manufacturing Technology Engineers
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• v.24 no.2
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• pp.148-154
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• 2015

Computer aided process planning (CAPP) keeps an important role between the design and manufacturing engineering processes. A CAPP system is a digital link between a computer aided design (CAD) model and manufacturing instructions. CAPP have been researched and applied in manufacturing filed, however, one manufacturing area where CAPP has not been extensively researched is rapid prototyping (RP). RP is a technique for creating directly a three dimensional CAD data into a physical prototype. RP enables to build physical models automatically and to use to reduce the time for the product development cycle as well as to improve the final quality of the designed product. Three-dimensional (3D) printing is one kind of RP that creates three-dimensional objects from CAD models. The paper presents a computer aided process planning system for printing medical products. 3D printing has been used to solve complex medical problems such as surgical instruments, bioengineered products, medical implants, and surgical guides.

• The Journal of Advanced Prosthodontics
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• v.10 no.3
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• pp.245-251
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• 2018

PURPOSE. To evaluate the accuracy of a model made using the computer-aided design/computer-aided manufacture (CAD/CAM) milling method and 3D printing method and to confirm its applicability as a work model for dental prosthesis production. MATERIALS AND METHODS. First, a natural tooth model (ANA-4, Frasaco, Germany) was scanned using an oral scanner. The obtained scan data were then used as a CAD reference model (CRM), to produce a total of 10 models each, either using the milling method or the 3D printing method. The 20 models were then scanned using a desktop scanner and the CAD test model was formed. The accuracy of the two groups was compared using dedicated software to calculate the root mean square (RMS) value after superimposing CRM and CAD test model (CTM). RESULTS. The RMS value ($152{\pm}52{\mu}m$) of the model manufactured by the milling method was significantly higher than the RMS value ($52{\pm}9{\mu}m$) of the model produced by the 3D printing method. CONCLUSION. The accuracy of the 3D printing method is superior to that of the milling method, but at present, both methods are limited in their application as a work model for prosthesis manufacture.

• Journal of rehabilitation welfare engineering & assistive technology
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• v.9 no.2
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• pp.145-151
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• 2015

In this paper, we proposed the fabrication methodology of orthotic device using 3D Computer-Aided Design programme and 3D printing technology based on images acquired from 3D scanner. We set the process and methodology of its fabrication method and confirmed whether it is available for clinical by fabricating four kinds of orthotic device for a patient with cerebral palsy. 3D printing technology method was indicated quantitatively and qualitatively about duration, tensile strength stronger comparing with conventional method, and we could propose that the 3D printing technology for the orthosis could be the proper method to mediate and compensate with reported problems related to orthosis.

• Maxillofacial Plastic and Reconstructive Surgery
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• v.37
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• pp.44.1-44.6
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• 2015

Background: The present study introduces the design and fabrication of a simple surgical guide with which to perform genioplasty. Methods: A three-dimensional reconstruction of the patient's cranio-maxilla region was built, with a dentofacial skeletal model, then derived from CT DICOM data. A surgical simulation was performed on the maxilla and mandible, using three-dimensional cephalometry. We then simulated a full genioplasty, in silico, using the three-dimensional (3D) model of the mandible, according to the final surgical treatment plan. The simulation allowed us to design a surgical guide for genioplasty, which was then computer-rendered and 3D-printed. The manufactured surgical device was ultimately used in an actual genioplasty to guide the osteotomy and to move the cut bone segment to the intended location. Results: We successfully performed the osteotomy, as planned during a genioplasty, using the computer-aided design and computer-aided manufacturing (CAD/CAM) surgical guide that we initially designed and tested using simulated surgery. Conclusions: The surgical guide that we developed proved to be a simple and practical tool with which to assist the surgeon in accurately cutting and removing bone segments, during a genioplasty surgery, as preoperatively planned during 3D surgical simulations.