• BMB Reports
• /
• v.51 no.6
• /
• pp.261-262
• /
• 2018

Aurora B is an important kinase involved in dynamic cellular events in mitosis. Aurora B activity is controlled by several post-translational modifications (PTMs). Among them, E3 ubiquitin ligase-mediated ubiquitination plays crucial roles in controlling the relocation and degradation of Aurora B. Aurora B, ubiquitinated by different E3 ligases, moves to the exact site for its mitotic function during metaphase-anaphase transition and is then degraded for cell cycle progression at the end of mitosis. However, how the stability of Aurora B is maintained until its degradation has been poorly understood. Recently, we have found that USP35 acts as a deubiquitinating enzyme (DUB) for Aurora B and affects its stability during cell division, thus being involved in the regulation of mitosis. In this review, we discuss the USP35-mediated deubiquitination of Aurora B and the regulation of mitotic progression by USP35.

• Transactions of the Korean Society of Mechanical Engineers
• /
• v.7 no.3
• /
• pp.270-277
• /
• 1983

Plastic plane stress solutions are given for a center cracked strip, characterized by the Ramberg-Osgood plastic index, under bi-axial tension. Using a power law hardening stress-strain relation, an incremental plasticity finite element formulation is developed, and simple formulation is given for computing J-integral with nodal displacements. The near tip angular distribution of von Mises effective stress doesn't differ significantly in magnitude according to the change of loading stress and bi-axial load combination factor. But, for smaller plastic index, the location of its maximum value moves vertically at a head of crack. J-integral value, in the plastic zone near crack tip, decreases with load combination factor for large and small plastic index.

• Journal of Photoscience
• /
• v.3 no.3
• /
• pp.127-132
• /
• 1996

Calcium has a variety of functions in neuron and muscle cells and blood clotting, especially in the visual system where dark adapted rods cotransport with Na$^+$ into the cell. An influx of Ca$^{2+}$ flows out of the cell through the Na$^+$ - Ca$^{2+}$ exchanger. By using a modified Ussing chamber in order to bring in vivo environment close, we have concluded that Ca$^{2+}$ blocks the activity of guanylate cyclase; in consequence, having an effect on the amplitude of electroretinogram (ERG). We suggest that Ca$^{2+}$ moves between the photoreceptor and the vitreous humor by way of certain Ca$^{2+}$ transport mechanisms. Also, the effect of Zn$^{2+}$ in Ca$^{2+}$ - free ringer solution caused an elevation of amplitude in ERG and a reduction of threshold.

• Journal of the Korean Society of Industry Convergence
• /
• v.19 no.3
• /
• pp.125-132
• /
• 2016

The swash-type piston pump is a device that discharges as much volume of hydraulic oil generated as it moves the ramp by controlling the angle of the swash. This pump is suitable for high-speed high pressurization, and due to its useful characteristic being the variable capacity-type, it is used as a main pump for heavy equipment in various fields such as defense, shipbuilding, construction, etc. This study intends to obtain optimal design values by conducting a structural analysis in order to verify its reliability during the design process of the newly developed swash-type piston pump.

• Journal of Electrical Engineering and Technology
• /
• v.8 no.3
• /
• pp.613-620
• /
• 2013

A new remote control algorithm for a mobile robot is proposed, where a remote controller consists of a camera and inertial sensors. Initially the relative position and orientation of a robot is estimated by capturing four circle landmarks on the plate of the robot. When the remote controller moves to point to the destination, the camera pointing trajectory is estimated using an inertial navigation algorithm. The destination is transmitted wirelessly to the robot and then the robot is controlled to move to the destination. A quick movement of the remote controller is possible since the destination is estimated using inertial sensors. Also unlike the vision only control, the robot can be out of camera's range of view.

• Journal of Information Science Theory and Practice
• /
• v.6 no.3
• /
• pp.37-44
• /
• 2018

An academic article is normally cited within a few years of publication, after which interest falls off as the research field moves on. However, an article is sometimes ignored for many years only to attract interest after a long period of dormancy. Such articles are called "Sleeping Beauties." A general characterization of this pattern has recently been defined and is used in this study to identify five Sleeping Beauties that were published by researchers at the University of Waterloo in the 1970s and 1980s. While a handful of studies have examined the occurrence of such Sleeping Beauties in specific fields of research or in a particular journal, none has yet identified these unusual articles in the context of the lasting impact of a university's research. This study is therefore a novel application of the latest technique for identifying Sleeping Beauties. The possibilities for using this unusual citation pattern in raising the profile of a university's research are discussed.

• Journal for History of Mathematics
• /
• v.31 no.3
• /
• pp.151-166
• /
• 2018

The rule of the game of Chomp is simple and the existence of a winning strategy can easily be proved. However, the existence tells us nothing about what strategies are winning in reality. Like in Chess or Baduk, many researchers studied the winning moves using computer programs, but no general patterns for the winning actions have not been found. In the paper, we aim to construct practical winning strategies based on backward induction. To do this we develop how to analyze Chomp and prove and find the winning strategies of the simple games of Chomp.

• Transactions of the Korean Society of Automotive Engineers
• /
• v.7 no.8
• /
• pp.208-215
• /
• 1999

Using the orthogonal arrays and the occupant analysis software based on the multi-body dynamics , two interactive design algorithms are proposed to improve the initial design of the occupant protection systems. Algorithm 1 sequentially moves the narrow design space within the upper and the lower design limit. Algorithm 2 sequentially reduces the relatively wide design space. Each design algorithm is composed of two levels . The first level is to improve the characteristics of the crash performance considering the noise factors. In order to obtain the robust design, the second level reduces the variations the noise factors. In order to obtain the robust design, the second level reduces the variations due to the tolerance of the design variable. To utilize the algorithm 1, HIC(Head Injury Criterion) , 3 msec criterion value of the chest acceleration and the femur load decreased by 27.4%, 10.4% and 55.8%, respectively. To utilizer the algorithm 2 , the results decreased by 38.0%, 10.5% and 3.0% , respectively.

• The Journal of Korea Robotics Society
• /
• v.1 no.2
• /
• pp.125-134
• /
• 2006

The problem of establishing the servo system to reach the desired location keeping all features in the field of view and following a straight line is considered. In addition, robustness of camera calibration parameters is considered in this paper. The proposed approach is based on switching from position-based visual servoing (PBVS) to image-based visual servoing (IBVS) and allows the camera path to follow a straight line. To achieve the objective, a pose estimation method is required; the camera's target pose is estimated from the obtained images without the knowledge of the object. A switched control law moves the camera equipped to a robot end-effector near the desired location following a straight line in Cartesian space and then positions it to the desired pose with robustness to camera calibration error. Finally simulation results show the feasibility of the proposed visual servoing technique.

• Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
• /
• v.22 no.3
• /
• pp.74-78
• /
• 2008

Conventionally, when we need to know about the dynamic characteristics of motors, the moving band method has been the first considerable technique. In this paper, we have investigated the moving material method that moves the property of the material in moving area elements of BLDC motors, instead of moving mesh elements of the rotor. From this method, we can reduce the demanded HDD memory for FEM analysis and the calculation time with same results.