• Title/Summary/Keyword: 3-level

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조기발병형 치주염의 표현형적 소집단의 IgG Subclass에 대한 연구 (The IgG subclass responses in the phenotypic subsets of the early-onset periodontitis)

  • 최점일
    • Journal of Periodontal and Implant Science
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    • 제29권1호
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    • pp.251-264
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    • 1999
  • 본 연구는 조기발병형 치주염의 서로 다른 4가지 표현형에 있어서 Porphyromonas gingivalis(Pg) 381과 Actinobacillus actinomycetemcomitans(Aa) Y4에 대한 상승된 IgG subclass의 양상을 평가하기 위해 시행하였다. Subform I(distinctive localized juvenile periodontitis pattern)에서 3명 subform II(post juvenile periodontitis pattern)에서 19명, subform III (localized but rapidly progressing pattern)에서 15명, subform IV(distinctive rapidly progressing periodontitis pattern)에서 15명의 환자를 조사하여 Pg에 대한 그들의 total IgG level과 각각의 IgG subclass level 및 Aa에 대한 IgG level을 검사했다. Pg에 대한 total IgG level은 subform II와 IV보다 subform I과 III에서 훨씬 높게 나타났다. IgG3 level이 subform I과 IV사이에서 현저한 차이가 있다는 점을 제외하고는, 다른 IgG subclass level에서 subform 사이에 아무런 차이가 없었다. Pg에 대한 IgG subclass는 single class 혹은 다양한 group에서 상승되어 나타났으며, IgG1+2+4가 가장 흔하게 발견되었고, 다음으로 IgG4 단독, IgG2 단독, IgG2+4, IgG2+3+4의 순으로 발견되었다. IgG2와 IgG4가 빈번히 상승되어 발견되었는데, 특히 severe form(subform III & IV)에서 그러했다. 뿐만 아니라, IgG level은 subform II, III, IV와 일치하여 점차적으로 증가하였고, 반면에 IgG1/IgG4 ratio는 그와 일치하여 감소되었다. 이러한 ratio의 감소는 단백질성의 오래된 항원의 과부하로 인해 immunoglobulin gene의 전환을 가능하게 한다는 것을 나타내고 있다. Aa에 대한 IgG2 level은 다른 유형보다 subform I에서 상당히 높았다. Pg에 대한 IgG2 levels이 subform I의 국소 부위에서 발생하는 disease activity와 밀접한 관련이 있으며, Aa의 경우에는 이러한 관련성이 나타나지 않았다. Pg에 대한 IgG2 level은 18-25세에서 훨씬 높은 동시에 26-35세에서는 감소했으며 결국 30대 후반에서는 더 높은 수치로 되돌아갔다. 이러한 결과는 Pg에 대한 IgG2 및 IgG responsiveness (single 혹은 combined)가 EOP의 severe form의 발달에 중요하게 작용하며 IgG2 levels은 IgG1/IgG4 ratio와 더불어 EOP의 localized type이 generalized type으로 계속 진행하는 것을 조절하는 역할을 하는 것으로 보인다는 것을 강하게 시사하였다.

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경남지방의 월강수량의 변동율과 Anomaly Level의 출현특성 (The Characteristics of the Anomaly Level and Variability of the Monthly Precipitation in Kyeongnam, Korea)

  • 박종길;이부용
    • 한국환경과학회지
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    • 제2권3호
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    • pp.179-191
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    • 1993
  • This paper aims to know the characteristics of occurrence of the anomaly level and variability of the monthly precipitation in Kyeongnam, Korea. For this study, it was investigated 주e distribution of the annual and cont비y mean precipitation, the precipitation variability and its annual change, and the characteristics of occurrence of the anomaly level in Kyeongnam area the results were summarized as follows : 1) she mean of annual total precipitation averaged over Kyeongnam area is 1433.3mm. I'he spatial distribution of the annual total precipitation shows that in Kyeongnam area, the high rainfall area locates in the southwest area and south coast and the low rainfall area in an inland area. 2) Monthly mean precipitation in llyeongnam area was the highest in July(266.4mm) 각lowed by August(238.0mm), June(210.2mm) in descending order. In summer season, rainfall was concentrated and accounted for 49.9 percent of the annual total precipitation. Because convergence of the warm and humid southwest current which was influenced by Changma and typhoon took place well in this area. 3) The patterns of annual change of precipitaion variability can be divided into two types; One is a coast type and the other an inland type. The variability of precipitation generally appears low in spring and summer season and high in autumn and winter season. This is in accord with the large and small of precipitation. 4) The high frequency of anomaly level was N( Normal)-level and the next was LN( Low Informal) -level and 25(Extremely Subnormal)-level was not appeared in all stations. The occurrence frequency of N level was high in high rainfall area and distinguish성 in spring and summer season but the low rainfall area was not. hey Words : anomaly level, variability, precipitation, coast type, inland type.

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폐경기 여성의 혈청 과산화지질 농도에 따른 항산화비타민의 영양상태 (The Nutritional Status of Antioxidant Vitamins in Relation to Serum MDA Level in Postmenopausal Women)

  • 정경아;김상연;최윤정;우정익;장유경
    • Journal of Nutrition and Health
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    • 제34권3호
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    • pp.330-337
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    • 2001
  • The purpose of this study was to investigate the nutritional status of antioxidant vitamins in relation to serum malondialdehye(MDA) level in postmenopausal women with common occurance of cardiovascular disease(CVD). Data about general characteristics including smoking, drinking and exercise status, dietary intake and serum level of antioxidant vitamins, and serum MDA level were collected from eighty-five postmenopausal women. Mean serum MDA level was 1.62$\pm$0.03nmol/ml, and general characteristics and serum lipid profiles were not significantly different among the three group: low MDA(<1.45nmol/ml), midium MDA(1.45-1.74nmol/ml) and high MDA($\geq$1.74nmol/ml). Total mean vitamin A intake was 472.8$\pm$37.7RE, 68% of RDA, vitamin C intake was 134.3$\pm$8.7mg, 192% of RDA and vitamin E intake was 8.6$\pm$0.5mg, 86% of RDA for Korean. In takes of antioxidant vitamins from the diet were not significantly different among the three groups. However significant negative correlation(r=-0.242, p<0.05) was observed between vitamin E intake and serum MDA level in total subjects. Total mean serum vitamin A, $\beta$-carotene and vitamin C level were 0.59$\pm$0.01$\mu\textrm{g}$/ml, 0.25$\pm$0.01$\mu\textrm{g}$/ml and 9.02$\pm$0.28$\mu\textrm{g}$/ml, respectively. Total mean serum vitamin E and vitamin E/total cholesterol level were 9.15$\pm$0.42$\mu\textrm{g}$/ml and 4.09$\pm$0.17$\mu\textrm{g}$/mg, respectively. Serum antioxidant vitamins levels were not significantly different among the three groups. However serum vitamin C and E level were negatively correlated to serum MDA level. We can conclude that it will be helpful for postmenopausal women with common occurance of CVD to improve nutritional status of antioxidant vitamins by increasing intakes of antioxidant vitamins, especially vitamin C and E. (Korean J Nutrition 34(3) : 330~337, 2001)

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보건교사의 학교건강증진사업의 중요성 인지도, 실천정도 및 지각된 수행능력정도에 관한 연구 (A Study on the Awareness of Importance, Performance Level, and Perceived Competence Level of School Health Promotion Programs)

  • 양순옥;권명순;정금희;이승희
    • 지역사회간호학회지
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    • 제20권1호
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    • pp.96-104
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    • 2009
  • Purpose: The purpose of this study was to provide fundamental materials for improving school health promotion programs by investigating school nurses' awareness of the importance, performance level, and perceived competence level of school health promotion programs in Gangwon-do. Methods: The subjects of this study were 173 school nurses who were working in Gangwon-do. The instrument for this study was a scale for awareness of importance, performance level, and perceived competence level. Data were collected on December 15, 2007 and analyzed using SPSS 13.0 for Windows. Results: The mean score of awareness of importance was 3.51(range: $1{\sim}4$). The mean score of performance level and the mean score of perceived competence level were 3.35 (range: $1{\sim}4$) and 3.29 (range: $1{\sim}4$), respectively. The younger school nurses were (F=4. 380, p=. 014 ), the higher their awareness of importance was. The performance level was lowest in high school nurses (F=5.013, p=.008). There were significant correlations between awareness of importance, performance level, and perceived competence level in school nurses. Conclusion: In order to improve the effectiveness of school health promotion programs, training and education programs for school nurses' competencies and technical support systems for school nurses should be provided.

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재난 취약성 분석에 관한 사례연구(N공단의 화재·폭발을 중심으로) (Case Study on the Analysis of Disaster Vulnerabilities (Focused on the Fire & Explosion in the N-Industrial Complex))

  • 하각천
    • 한국안전학회지
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    • 제36권2호
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    • pp.94-100
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    • 2021
  • In general, the industrial complex is a place where factories of various industries are concentrated. It is only as efficient as it is designed. However, the risks vary as there are various industries. These features are also associated with various types of disasters. The dangers of natural disasters such as a typhoon, flood, and earthquake, as well as fire and explosions, are also latent. Many of these risks can make stable production and business activities difficult, resulting in massive direct and indirect damage. In particular, decades after its establishment, the vulnerabilities increase even more as aging and small businesses are considered. In this sense, it is significant to assess the vulnerability of the industrial complex. Thus analysing fire and explosion hazards as stage 1 of the vulnerability evaluation for the major potential disasters for the industrial complex. First, fire vulnerabilities were analyzed quantitatively. It is displayed in blocks for each company. The assessment block status and the fire vulnerability rating status were conducted by applying the five-step criteria. Level A is the highest potential risk step and E is the lowest step. Level A was 11.8% in 20 blocks, level B was 22.5% in 38 blocks, level C was 25.4% in 43 blocks, level D was 26.0% in 44 blocks, and level E was 14.2% in 24 blocks. Levels A and B with high fire vulnerabilities were analyzed at 34.3%. Secondly, the vulnerability for an explosion was quantitatively analyzed. Explosive vulnerabilities were analyzed at 4.7% for level A with 8 blocks, 3.0% for level B with 5, 1.8% for level C with 3, 4.7% for level D with 8, and 85.8% for level E with 145. Levels A and B, which are highly vulnerable to explosions, were 7.7 %. Thirdly, the overall vulnerability can be assessed by adding disaster vulnerabilities to make future assessments. Moreover, it can also assist in efficient safety and disaster management by visually mapping quantified data. This will also be used for the integrated control center of the N-Industrial Complex, which is currently being installed.

A Visualization Tool for Computational Analysis of DNA Methylation Level Using Bisulfite Sequencing Data

  • Tae, Hong-Seok
    • Genomics & Informatics
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    • 제9권3호
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    • pp.136-137
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    • 2011
  • Methylation of cytosine is a post-synthesis modification that does not affect the primary DNA sequence but greatly influences gene expression level and phenotypes of an organism. As high-throughput sequencing of bisulfite-treated DNA is the most efficient method to identify methylated sites, several tools to map sequencing reads on a reference are available. But tools to visualize and to interpret the methylation level of methylation sites are currently insufficient. Herein, we present a novel tool to visualize the methylation level of CpG sites.

3D PLM(Product Life cycle Management) & CPC(Collaborative Product Commerce)

  • Choi, Woo-Suk
    • 한국전자거래학회:학술대회논문집
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    • 한국전자거래학회 2001년도 International Conference CALS/EC KOREA
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    • pp.597-614
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    • 2001
  • Level 0: The Marekting Buzzword : □Confusion between DMU and Visualization □Having a Mobile Data Viewer/Analyser is Anyway a Prerequisite Level 1: Digital Pre-Assembly (DPA): □Building Digital Prototype before Physical Build □Usually a job for Packaging or Prototype Teams □Usually no time Left to take Feed-back into account before Actual Build Level 2: Design in Context: □All Designers within Car Maker do Local DMU before DPA Level 3: Design in Extended Context □Design in Context Expanded to Suppliers(omitted)

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수중용 레벨메터의 제작 및 펄스-에코 특성 (Fabrication and Pulse-echo Response of Level-Meter for Underwater)

  • 양윤석;김철한;사공건
    • 대한전기학회:학술대회논문집
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    • 대한전기학회 1999년도 추계학술대회 논문집 학회본부 C
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    • pp.935-937
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    • 1999
  • In this study, 1-3 type composite specimens were fabricated with PZT powders prepared by the molten-salt synthesis method and Eccogel polymer matrix. A virtual level-meter was fabricated with a 1-3 type composite probe and electronic unit for underwater application. There was no difference in values between a virtual and measured level on its level meter.

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