Romo, L.;Benavent-Climent, A.;Morillas, L.;Escolano, D.;Gallego, A.
Earthquakes and Structures
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v.8
no.3
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pp.485-509
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2015
This paper presents the experimental results obtained by applying frequency-domain structural health monitoring techniques to assess the damage suffered on a special type of damper called Web Plastifying Damper (WPD). The WPD is a hysteretic type energy dissipator recently developed for the passive control of structures subjected to earthquakes. It consists of several I-section steel segments connected in parallel. The energy is dissipated through plastic deformations of the web of the I-sections, which constitute the dissipative parts of the damper. WPDs were subjected to successive histories of dynamically-imposed cyclic deformations of increasing magnitude with the shaking table of the University of Granada. To assess the damage to the web of the I-section steel segments after each history of loading, a new damage index called Area Index of Damage (AID) was obtained from simple vibration tests. The vibration signals were acquired by means of piezoelectric sensors attached on the I-sections, and non-parametric statistical methods were applied to calculate AID in terms of changes in frequency response functions. The damage index AID was correlated with another energy-based damage index -ID- which past research has proven to accurately characterize the level of mechanical damage. The ID is rooted in the decomposition of the load-displacement curve experienced by the damper into the so-called skeleton and Bauschinger parts. ID predicts the level of damage and the proximity to failure of the damper accurately, but it requires costly instrumentation. The experiments reported in this paper demonstrate a good correlation between AID and ID in a realistic seismic loading scenario consisting of dynamically applied arbitrary cyclic loads. Based on this correlation, it is possible to estimate ID indirectly from the AID, which calls for much simpler and less expensive instrumentation.
A rapid, sensitive, and specific enzyme-linked immuno-sorbent assay (ELISA) for bovine casein was developed. Biotinylated casein and peroxidase-conjugated avidin were used in the assay with antibody separated from yolks of immunized hens. Caseins were biotinylated with sulfo-N-hydroxy succinimido biotin and peroxi-dase-conjugated avidin bound the biotinylated casein which became bound to immobilized anti-body on a microplate. The antibodies were specific for bovine $\alpha$- and $\beta$-caseins, and their cross-reactivities with whey proteins, IgG, and serum albumin from bovine were not detectable by ELISA and Western blot. Various sensitivities ranging from 2ng/ml to 20${\mu}\textrm{g}$/ml of casein were achieved, and were controlled by adding vanous concentrations of the biotinylated casein. Parallelism was observed between standard and sample curves. The coefficients of variation of intra-assays and inter-assays from the most sensitive assay were 5.5 and 5.7%, respectively, at the 50% displacement. Casein contents of peripaturient milk samples showed that casein secretion rapidly increased 3d prepartum.
Kim, Seong-Il;Kim, Hee-Jin;Kwak, Jin-Hwan;Kim, In-Chull;Lee, Chang-Ho
Biomolecules & Therapeutics
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v.3
no.4
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pp.322-326
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1995
General pharmacology of LB20304, a quinolone antibiotic, were examined in terms of general behaviour, cardiovascular, and central nervous system. LB20304 at oral dose of 2,000 mg/kg did not induce significant behavioural changes in mice. In contrast with ciprofloxacin, LB20304 at dose of 20 mg/kg, iv. did not show any observable effects on the blood pressure in rats. Displacement of [$^3$H]muscimol binding to the rat brain synaptic membranes was measured. LB20304 was shown to be about five times less potent than ciprofloxacin in specific GABA receptor binding. Drug interaction between LB20304 and 4-biphenyl acetic acid, an active metabolite of fenbufen, was assessed in mice by measuring convulsion and/or subsequent death. A single oral pretreatment with 4-BPA at 400 mg/kg increased the incidence of convulsion and death after oral administration of ciprofloxacin at the doses of 25, 50, and 100 from zero of five to three of five, two of five, and four of five, respectively, whereas LB20304 alone or combination with 4-BPA caused neither convulsions nor death at the doses of 12.5, 25, 50, and 100 mg/kg, respectively. Quinolones-induced epileptogenic activities were assessed by a direct intracerebral injection of test articles. The CD$_{50}$ values (nmole) are as follows; 169.47, 35.36, 105.29, and 88.67 for LB20304, ciprofloxacin, of loxacin, and lomefloxacin, respectively. From these data, LB 20304 at therapeutic doses seems to be much more safe than any other quinolones tested.d.
Journal of the Society of Naval Architects of Korea
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v.58
no.3
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pp.198-205
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2021
In this paper, the effect of trim variation on the required power of 11,000TEU container ship was investigated under conditions considering the actual operation speed and draft. For each draft condition, the effective power (PE) and delivered power (PD) trends were investigated with changes in trim and ship speed. At this time, the displacement volume was fixed same as the value of the even trim condition and the both sinkage at the fore and after perpendicular are confirmed. The test ship speeds were determined by considering the operating speed. Both numerical and experimental methods were used to analyze the effects of trim variation. Numerical analysis results were used for evaluating the resistance performance, and the self-propulsion performance was estimated using experimental data obtained from model test.
This paper presents the investigation of two types of rotordynamic modeling issues for 2.2 kW-class, rated speed of 1,800 rpm, squirrel-cage type induction motors. These issues include the lamination structure of rotor cores, and the radial clearance of ball bearings that support the shaft of the motor. Firstly, we focus on identifying the effects of rotor core lamination on the rotordynamic analysis via a 2D prediction model. The influence of lamination is considered as the change in the elastic modulus of the rotor core, which is determined by a modification factor ranging from 0 to 1.0. The analysis results show that the unbalanced response of the rotor-bearing system significantly varies depending on the value of the modification factor. Through modal testing of the system, the modification factor of 0.079 is proven to be appropriate to consider the effects of lamination. Next, we investigate the influence of ball bearing clearance on the rotordynamic analysis by establishing a bearing analysis model based on Hertz's contact theory. The analysis results indicate that negative clearance greatly changes the bearing static behavior. Rotordynamic analysis using predicted bearing stiffness with various clearances from -0.005 mm to 0.010 mm reveals that variations in clearance result in a slight difference in the displacement of the system up to 18.18. Thus, considering lamination in rotordynamic analysis is necessary as it can cause serious analysis errors in unbalanced response. However, considering the effect of the bearing clearance is optional because of its relatively weak impact.
This paper introduces a new efficient analytical method, based on shear deformations obtained with 2D elasticity theory approach, to perform an explicit closed-form solution for calculation the interfacial shear and normal stresses in plated RC beam. The materials of plate, necessary for the reinforcement of the beam, are in general made with fiber reinforced polymers (Carbon or Glass) or steel. The experimental tests showed that at the ends of the plate, high shear and normal stresses are developed, consequently a debonding phenomenon at this position produce a sudden failure of the soffit plate. The interfacial stresses play a significant role in understanding this premature debonding failure of such repaired structures. In order to efficiently model the calculation of the interfacial stresses we have integrated the effect of shear deformations using the equilibrium equations of the elasticity. The approach of this method includes stress-strain and strain-displacement relationships for the adhesive and adherends. The use of the stresses continuity conditions at interfaces between the adhesive and adherents, results pair of second-order and fourth-order coupled ordinary differential equations. The analytical solution for this coupled differential equations give new explicit closed-form solution including shear deformations effects. This new solution is indented for applications of all plated beam. Finally, numerical results obtained with this method are in agreement of the existing solutions and the experimental results.
Nowadays, more and more subway tunnels were planed and constructed underneath the ground of urban cities to relieve the congested traffic. Potential damage may occur in existing tunnel if the new tunnel is constructed too close. So far, previous studies mainly focused on the tunnel-tunnel interactions with circular shape. The difference between circular and horseshoe shaped tunnel in terms of deformation mechanism is not fully investigated. In this study, three-dimensional numerical parametric studies were carried out to explore the effect of different tunnel shapes on the complicated tunnel-tunnel interaction problem. Parameters considered include volume loss, tunnel stiffness and relative density. It is found that the value of volume loss play the most important role in the multi-tunnel interactions. For a typical condition in this study, the maximum invert settlement and gradient along longitudinal direction of horseshoe shaped tunnel was 50% and 96% larger than those in circular case, respectively. This is because of the larger vertical soil displacement underneath existing tunnel. Due to the discontinuous hoop axial stress in horseshoe shaped tunnel, significant shear stress was mobilized around the axillary angles. This resulted in substantial bending moment at the bottom plate and side walls of horseshoe shaped tunnel. Consequently, vertical elongation and horizontal compression in circular existing tunnel were 45% and 33% smaller than those in horseshoe case (at monitored section X/D = 0), which in latter case was mainly attributed to the bending induced deflection. The radial deformation stiffness of circular tunnel is more sensitive to the Young's modulus compared with horseshoe shaped tunnel. This is because of that circular tunnel resisted the radial deformation mainly by its hoop axial stress while horseshoe shaped tunnel do so mainly by its flexural rigidity. In addition, the reduction of soil stiffness beneath the circular tunnel was larger than that in horseshoe shaped tunnel at each level of relative density, indicating that large portion of tunneling effect were undertaken by the ground itself in circular tunnel case.
$\underline{Purpose}$: Using cone beam CT, we can compare the position of the patients at the simulation and the treatment. In on-line image guided radiation therapy, one can utilize this compared data and correct the patient position before treatments. Using cone beam CT, we investigated the errors induced by setting up the patients when use only the markings on the patients' skin. $\underline{Materials\;and\;Methods}$: We obtained the data of three patients that received radiation therapy at the Department of Radiation Oncology in Chung-Ang University during August 2006 and October 2006. Just as normal radiation therapy, patients were aligned on the treatment couch after the simulation and treatment planning. Patients were aligned with lasers according to the marking on the skin that were marked at the simulation time and then cone beam CTs were obtained. Cone beam CTs were fused and compared with simulation CTs and the displacement vectors were calculated. Treatment couches were adjusted according to the displacement vector before treatments. After the treatment, positions were verified with kV X-ray (OBI system). $\underline{Results}$: In the case of head and neck patients, the average sizes of the setup error vectors, given by the cone beam CT, were 0.19 cm for the patient A and 0.18 cm for the patient B. The standard deviations were 0.15 cm and 0.21 cm, each. On the other hand, in the case of the pelvis patient, the average and the standard deviation were 0.37 cm and 0.1 cm. $\underline{Conclusion}$: Through the on-line IGRT using cone beam CT, we could correct the setup errors that could occur in the conventional radiotherapy. The importance of the on-line IGRT should be emphasized in the case of 3D conformal therapy and intensity-modulated radiotherapy, which have complex target shapes and steep dose gradients.
Journal of Korean Tunnelling and Underground Space Association
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v.25
no.6
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pp.423-446
/
2023
Shield TBM tunnel linings are segmented into segments and rings. This study investigates the response characteristics of the stress and displacement of the segment lining under seismic waves through modeling that considers the interface behavior between segments by applying a shell interface element to the contact surface between segments and rings. And there is no management criteria for ovaling deformation of segment linings in Korea. So, this study the ovality criteria and meaning of segment lining. The results of study showed that the distribution patterns of stress and displacement under seismic waves were similar between continuous linings and segment linings. However, the maximum values of stress and displacement showed differences from segment linings. The stress distribution of the continuous lining modeled as a shell type has a stress distribution that has continuity in the 3D cylindrical shape, but the segment lining is concentrated outside the segment, and the largest stress occurs at the location where the contact surface between the segment and the ring is concentrated. This intermittent and localized stress distribution shows an increasing as the ovality of the lining increases at seismic waves. The ovality at which the increase in stress distribution begins to show irregularity and localization is about 150‰. Ovality of 150‰ is an unrealistic value that cannot represent actual lining deformation. Therefore, the ovality of the segment lining increase with depth, but it does not have a significant impact on the stability caused by seismic load.
So, Jae Moo;Kang, Sung-Sun;Hong, AhReum;Jung, Jong Min;Kim, Jai Jeong
Korean Journal of Applied Biomechanics
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v.26
no.4
/
pp.343-351
/
2016
Objective: The purpose of this study was to help improve game performance and provide preliminary data to enhance the efficiency of the kick and stability of the support foot by comparing the kinematic characteristics of the repeated side kick (geodeupyeopchagi) in poomsaeKoryo between expert and non-expert groups. Method: The subjects were divided into 2 groups according to proficiency in Taekwondo, an expert group and a non-expert group (n = 7 in each group), to observe the repeated side-kick technique. Four video cameras were set at a speed of 60 frames/sec and exposure time of 1/500 sec to measure the kinematic factors of the 2 groups. The Kwon3D XPprogramas used to collect and analyze three-dimensional spatial coordinates. Ground reaction force data were obtained through a force plate with a 1.200-Hz frequency. An independent samplesttest was performed, and statistical significance was defined as .05. The SPSS 18.0 software was used to calculate the mean and standard deviation of the kinematic factors and to identify the difference between the experts and non-experts. Results: The angular displacement of the hip joint in both the expert and non-expert groups showed statistical significance on E1 and E4 of the left support foot and E5 of the right foot (p<.05). The angle displacement of the knee joint in both groups showed statistical significance on E4 of the left support foot, and E1 and E2 of the right foot (p<.05). The angular velocity of the lower leg in both groups showed no statistical significance on the left support foot but showed statistical significance on E2 and E6 of the right foot (p<.05). The angular velocity of the foot in both groups showed no statistical significance on the left support foot but showed statistical significance on E2 of the right foot (p<.05). The vertical ground reaction force in both groups showed statistical significance on E2 (p<.05). The center of pressure in all directions in both groups showed statistical significance (p<.5). Conclusion: While performing the repeated side kick (geodeupyeopchagi), the experts maintainedconsistency and stability of the angle of the support leg while the kick foot moved high and fast. On the other hand, the angle of the support foot of non-experts appeared inconsistent, and the kick foot was raised, relying on the support leg, resulting in unstable and inaccurate movement.
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