• 한국시스템다이내믹스연구
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• 제7권2호
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• pp.57-80
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• 2006

Nuclear technology made a great contribution to the national economy and society by localization of nuclear power plant design, and by stabilization of electricity price, etc. It is very important to conduct the retrospective analysis for the nuclear technology contribution to the national economy and society, but it is more important to conduct prospective analysis for the nuclear technology contribution. The term "technology value" is often used in the prospective analysis to value the result of technology development. There are various definitions of technology value, but generally it means the increment of future revenue or the reduction of future cost by technology development. These technology valuation methods are widely used in various fields (information technology or energy technology, etc). The main objective of this research is to develop valuation methodology that represents unique characteristics of nuclear power technology. The valuation methodology that incorporates market share changes of generation technologies was developed. The technology valuation model which consists of five modules (electricity demand forecast module, technology development module, market share module, electricity generation module, total cost module) to incorporate market share changes of generation technologies was developed. The nuclear power technology value assessed by this technology valuation model was 3 times more than the value assessed by the conventional method. So it was confirmed that it is very important to incorporates market share changes of generation technologies. The valuation results of nuclear power technology in this study can be used as policy data for ensuring the benefits of nuclear power R&D (Research and Development) investment.

• ETRI Journal
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• 제27권2호
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• pp.153-165
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• 2005

The main purpose of a spatial audio system is to give a listener the same impression as if he/she were present in a recorded environment. A dummy head microphone is generally used for such purposes. Because of its human-like shape, we can obtain good spatial sound images. However, its shape is a restriction on its public use and it is difficult to convert a 2-channel recording into multi-channel signals for an efficient rendering over a multi-speaker arrangement. In order to solve the problems mentioned above, a spatial audio system is proposed that uses multiple microphones on a rigid sphere. The system has five microphones placed on special points of the rigid sphere, and it generates audio signals for headphone, stereo, stereo dipole, 4-channel, and 5-channel reproduction environments. Subjective localization experiments show that front/back confusion, which is a common limitation of spatial audio systems using the dummy head microphone, can be reduced dramatically in 4-channel and 5-channel reproduction environments and can be reduced slightly in a headphone reproduction.

• 한국정보처리학회논문지
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• 제7권5호
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• pp.1361-1369
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• 2000

For the implementation of 3D Sound Localization system, the binaural filtering by HRTFs is generally employed. But the HRTF filter is of high order and its coefficients for all directions have to be stored, which imposes a rather large memory requirement. To cope with this, research works have centered on obtaining low dimensional HRTF representations without significant loss of information and synthesizing the original HRTF efficiently, by means of feature extraction methods for multivariate dat including PCA. In these researches, conventional linear PCA was applied to the frequency domain HRTF data and using relatively small number of principal components the original HRTFs could be synthesized in approximation. In this paper we applied neural network based nonlinear PCA model (NLPCA) and the nonlinear PLS repression model (NLPLS) for this low dimensional HRTF modeling and analyze the results in comparison with the PCA. The NLPCA that performs projection of data onto the nonlinear surfaces showed the capability of more efficient HRTF feature extraction than linear PCA and the NLPLS regression model that incorporates the direction information in feature extraction yielded more stable results in synthesizing general HRTFs not included in the model training.

• Archives of Pharmacal Research
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• 제21권5호
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• pp.496-502
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• 1998

The present study was carried out to determine the possible use of cTn-I in the cardiac myofibrillar architecture, as a potential target for in vivo radioimmunodetection of cardiac damage in a brain death pig model. Radioiodiantion of the anti-cTn-I 5F4 McAb was carried out by lactoperoxidase method. the percentage iodine incorporation achieved was 70-75%. The radioiodinated McAbs were purified on Sephadex G-25 column and characterised by Paper chromatography, Phast Gel electrophoresis and electroimmunoblotting. Radioiodinated anticTn-I 5F4 McAbs were employed alongside Pyrophosphate($Tc_{99m}$-PPi$) and $Thallium^{201}$ chloride($TI^{201}$) in 24 landrace pigs (brain-dead=18 & sham-operated=6). The percentage cardiac uptake of the radiolabelled antibody injected dose was significantly higher in the brain dead animals(0.196%) as compared to that of sham-operated animals (0.11%). Specific in vivo localization of radiolabelled McAbs in the infarcted cardiac tissue was confirmed by computer-aided reconstruction of 3-D images of the isolated heart. The preliminary results of the study revealed preferential uptake of radiolabelled antibody at the site of myocyte damage resulting from artificially induced brain death.

• Journal of Radiation Protection and Research
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• 제36권4호
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• pp.195-199
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• 2011

The use of intravenous catheters are occasionally complicated by intravascular fragments and swelling of the catheter fragments. We present a patient in whom an intravenous catheter fragments was retrieved from the dorsal metacarpal vein following its incidental CT examination detection. The case of demonstrates the utility of microscopy and multi-detector CT in localizing small of subtle intravenous catheter fragments as a human error. A case of IV catheter fragments in the metacarpal vein, in which reproducible and microscopy data allowed complete localization of a missing fragments and guided surgery with respect to the optimal incision site for fragments removal. These reproducible studies may help to determine the best course of action and treatment for the patient who presents with such a case.

• 한국군사과학기술학회지
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• 제5권2호
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• pp.169-184
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• 2002

In order to extract bearing information from the directional sensors of DIFAR(directional frequency analysis and recording) that is a kind of passive sonobuoy, the cardioid beamforming algorithm applicable to DIFAR system was studied in the frequency domain. the algorithm uses narrow-band signals propagated though the media from the acoustic sources such as ship machineries. The proposed algorithm is expected to give signal to noise ratio of 6dB when it uses the maximum response axis(MRA) among the Cardioid beams. The estimated bearings agree very well with those from GPS data. Assuming the bearings from GPS data to be real values, the estimation errors are analyzed statistically. The histogram of estimation errors in each frequency have Gaussian shape, the mean and standard deviation dropping in the ranges -1.1~$6.7^{\circ}$ and 13.3~$43.6^{\circ}$, respectively. Estimation errors are caused by SMR degradation due to propagation loss between the source and receiver, daily fluctuating geo-magnetic fields, and non-stationary background noises. If multiple DIFAR systems are employed, in addition to bearing, range information could be estimated and finally localization or tracking of a target is possible.

• International Journal of Aerospace System Engineering
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• 제5권2호
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• pp.1-7
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• 2018

This study examines the history of Korean aviation industry and presents the investment strategy based on the evidence and the 4th industrial revolution. Looking at the evolution of the Korean aviation industry and its technological development will be a great help to support industrial and technological innovation in the future. The modern aviation industry is divided into stages of development, focusing on maintenance of equipment introduced in advanced countries, localization through license assembly, production of products based on technology, and international joint development. The development of aeronautics technology has been progressing towards a general improvement of economic efficiency, aircraft safety efficiency through environmental-friendliness, unmanned operation, and downsizing. The Korea Aerospace Research Institute has secured key technologies through development of several aircrafts such as Experimental Aircraft Kachi, EXPO Unmanned Airship, Twin-engine Composite Aircraft, Canard Aircraft, Multi-Purpose Stratosphere unmanned-airship, Medium Aerostats, Smart UAV, Surion, EAV-2H, KC-100, and OPV. The development strategy is discussed at the level of the evidence-based investment strategy that is currently being discussed, and so the investment priorities in aircraft is high. Current drone usage and development direction are not only producing parts using 3D printer, but also autonomous flight, communication (IoT, 5G), information processing (big data, machine learning). Therefore, the aviation industry is expected to lead the fourth industrial revolution.

• Structural Engineering and Mechanics
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• 제72권2호
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• pp.191-201
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• 2019

Finite element analysis is one of the most used tools for studying femoral neck fracture. Nerveless, consensus concerning either the choice of material characteristics, damage law and /or geometric models (linear on nonlinear) remains unreached. In this work, we propose a numerical quasi-brittle damage model to describe the behavior of the proximal femur associated with two methods to evaluate the Young modulus. Eight proximal femur finite elements models were constructed from CT scan data (4 donors: 3 women; 1 man). The numerical computations showed a good agreement between the numerical curves (load - displacement) and the experimental ones. A very encouraging result is obtained when a comparison is made between the computed fracture loads and the experimental ones ($R^2=0.825$, Relative error =6.49%). All specific numerical computation provided very fair qualitative matches with the fracture patterns for the sideway fall simulation. Finally, the comparative study based on 32 simulations adopting linear and nonlinear meshing led to the conclusion that the quantitatively results are improved when a nonlinear mesh is used.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제15권5호
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• pp.1778-1797
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• 2021

Document image binarization is an important pre-processing step in document analysis and archiving. The state-of-the-art models for document image binarization are variants of encoder-decoder architectures, such as FCN (fully convolutional network) and U-Net. Despite their success, they still suffer from three limitations: (1) reduced feature map resolution due to consecutive strided pooling or convolutions, (2) multiple scales of target objects, and (3) reduced localization accuracy due to the built-in invariance of deep convolutional neural networks (DCNNs). To overcome these three challenges, we propose an improved semantic segmentation model, referred to as DP-LinkNet, which adopts the D-LinkNet architecture as its backbone, with the proposed hybrid dilated convolution (HDC) and spatial pyramid pooling (SPP) modules between the encoder and the decoder. Extensive experiments are conducted on recent document image binarization competition (DIBCO) and handwritten document image binarization competition (H-DIBCO) benchmark datasets. Results show that our proposed DP-LinkNet outperforms other state-of-the-art techniques by a large margin. Our implementation and the pre-trained models are available at https://github.com/beargolden/DP-LinkNet.

• Molecules and Cells
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• 제46권4호
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• pp.200-205
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• 2023

DNA-dependent protein kinase catalytic subunit (DNA-PKcs), a member of the phosphatidylinositol 3-kinase-related kinase family is a well-known player in repairing DNA double-strand break through non-homologous end joining pathway. This mechanism has allowed us to understand its critical role in T and B cell development through V(D)J recombination and class switch recombination, respectively. We have also learned that the defects in these mechanisms lead to the severely combined immunodeficiency (SCID). Here we highlight some of the latest evidence where DNA-PKcs has been shown to localize not only in the nucleus but also in the cytoplasm, phosphorylating various proteins involved in cellular metabolism and cytokine production. While it is an exciting time to unveil novel functions of DNA-PKcs, one should carefully choose experimental models to study DNA-PKcs as the experimental evidence has been shown to differ between cells of defective DNA-PKcs and those of DNA-PKcs knockout. Moreover, while there are several DNA-PK inhibitors currently being evaluated in the clinical trials in an attempt to increase the efficacy of radiotherapy or chemotherapy, multiple functions and subcellular localization of DNA-PKcs in various types of cells may further complicate the effects at the cellular and organismal level.