• Title/Summary/Keyword: 3-D Hydrodynamic Focusing

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Effects of Geometric and Flow Conditions on 3-dimensional Hydrodynamic Focusing (3 차원 유체역학 집속에 대한 채널 형상 및 유동 조건의 매개변수 연구)

  • Han, Kyung-Sup;Kim, Dong-Sung
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.34 no.1
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    • pp.61-66
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    • 2010
  • In our previous work, 3-dimensional hydrodynamic focusing microfluidic device (3D-HFMD) has been developed with the help of locally increased aspect ratio of thickness to width without any horizontal separation wall. In this study, we have investigated 3-dimensional hydrodynamic focusing behaviors inside the 3D-HFMD according to the various geometric and flow conditions. The parametric study has been extensively carried out for the effects of geometric and flow conditions on 3-dimensional hydrodynamic focusing with both 3D-HFMD and previous microfluidic device design based on three-dimensional computational fluid dynamics (CFD) simulations. The CFD simulations suggested the proper design window of channel geometry and flow conditions.

Analysis of 3-Dimensional Hydrodynamic Focusing in Circular Capillary Tube and Rectangular Microchannel (원형 모세관과 사각형 단면의 미세채널에서 3차원 수력학적 집속유동 분석)

  • Yoon, Seong-Hee;Kim, Kyung-Hoon;Kim, Jung-Kyung
    • Journal of the Korean Society of Visualization
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    • v.9 no.2
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    • pp.21-26
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    • 2011
  • Hydrodynamic focusing technique to generate focused flow has been used for flow cytometry in microfluidic devices. However, devices with circular capillary tubes made of glass are not suitable for flow visualization or optical signal detection because the rays of light are distorted at the curved interface. We devised a new acrylic chamber assembled with a pulled micropipette and a rectangular microchannel made of glass. This new channel geometry enabled us to visualize the three-dimensional (3D) flow characteristics with confocal imaging technique. We analyzed the 3D hydrodynamic focusing in a circular capillary tube and a rectangular microchannel over a practical range of flow rates, viscosities and pressure drops.

On-Chip Fabrication of PDA Sensor Fiber Using Laser Polymerization and 3-D Hydrodynamic Focusing (3-D 유체집속효과와 레이저 중합반응을 이용한 PDA 센서 미세섬유 제작)

  • Yoo, Im-Sung;Song, Si-Mon
    • Proceedings of the KSME Conference
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    • 2008.11b
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    • pp.2692-2695
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    • 2008
  • Polydiacetylene (PDA) is chemosensor materials that exhibit non-fluorescent-to-fluorescent transition as well as blue-to-red visible color change upon chemical or thermal stress. They have been studied in forms of film or microarray chip, so far. In this paper, we provide a novel technique to fabricate continuous micro-fiber PDA sensor using in-situ laser-polymerization technique and 3-D hydrodynamic focusing on a microfluidic chip. The flow of a monomer solution with diacetylene (DA) monomer is focused by a sheath flow on a 3-D microfluidic chip. The focused flow is exposed to 365 nm UV laser beam for in-situ polymerization which generates a continuous fiber containing DA monomers. Then, the fiber is exposed to 254 nm UV light to polymerize DA monomers to PDA. Preliminary results indicate that the fiber size can be controlled by the flow rates of the monomer solution and sheath flows and that a PDA sensor fiber successively responds to chemical and thermal stress.

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Microfluidic Fabrication of Conjugated Polymer Sensor Fibers (미세유동을 이용한 공액 고분자 센서 섬유 제작)

  • Yoo, Imsung;Song, Simon
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.38 no.10
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    • pp.853-858
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    • 2014
  • We propose a fabrication method for polydiacetylene (PDA)-embedded hydrogel microfibers on a microfluidic chip. These fibers can be applied to the detection of cyclodextrines (CDs), which are a family of sugar and aluminum ions. PDA, a family of conjugated polymers, has unique characteristics when used for a sensor, because it undergoes a blue-to-red color transition and nonfluorescence-to-fluorescence transition in response to environmental stimulation. PDAs have different sensing characteristics depending on the head group of PCDA. By taking advantage of ionic crosslinking-induced hydrogel formation and the 3D hydrodynamic focusing effect on a microfluidic chip, PCDA-EDEA-derived diacetylene (DA) monomer-embedded microfibers were successfully fabricated. UV irradiation of the fibers afforded blue-colored PDA, and the resulting blue PDA fibers underwent a phase transition to red and emitted red fluorescence upon exposure to CDs and aluminum ions. Their fluorescence intensity varied depending on the CDs and aluminum ion concentrations. This phase transition was also observed when the fibers were dried.

3D Numerical Modelling of Water Flow and Salinity Intrusion in the Vietnamese Mekong Delta

  • Lee, Taeyoon;Nguyen, Van Thinh
    • Proceedings of the Korea Water Resources Association Conference
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    • 2021.06a
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    • pp.207-207
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    • 2021
  • The Vietnamese Mekong Delta(VMD) covers an area of 62,250 km2 in the lowest basin of the Mekong Delta where more than half of the country's total rice production takes place. In 2016, an estimated 1.29 million tonnes of Vietnam's rice were lost to the country's biggest drought in 90 year and particularly in VMD, at least 221,000 hectares of rice paddies were hit by the drought and related saltwater intrusion from the South China Sea. In this study, 3D numerical simulations using Delft3D hydrodynamic models with calibration and validation process were performed to examine flow characteristics, climate change scenarios, water level changes, and salinity concentrations in the nine major estuaries and coastal zones of VMD during the 21st century. The river flows and their interactions with ocean currents were modeled by Delft3D and since the water levels and saltwater intrusion in the area are sensitive to the climate conditions and upstream dam operations, the hydrodynamic models considered discharges from the dams and climate data provided by the Coupled Model Intercomparison Project Phase 6(CMIP6). The models were calibrated and verified using observational water levels, salinity distribution, and climate change data and scenarios. The results agreed well with the observed data during calibration and validation periods. The calibrated models will be used to make predictions about the future salinity intrusion events, focusing on the impacts of sea level rise due to global warming and weather elements.

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Large scale flood inundation of Cambodia, using Caesar lisflood

  • Sou, Senrong;Kim, Joo-Cheol;Lee, Hyunsoek;Ly, Sarann;Lee, Giha;Jung, Kwansue
    • Proceedings of the Korea Water Resources Association Conference
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    • 2015.05a
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    • pp.211-211
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    • 2015
  • Mekong River is the world's $10^{th}$ longest river and runs through China's Yunnan province, Burma, Thailand, Laos, Cambodia and Vietnam. And Tonle Sap Lake, the largest fresh water body in Southeast Asia and the heart of Mekong River system, covers an area $2,500-3,000Km^2$ in dry season and $10,000-16,000Km^2$ in wet season. As previously noted, the water within Sap river flows from the Mekong River to Tonle Sap Lake in flood season (between June and October) and backward to Mekong River in dry season. Recently the flow regime of Sap River might be significantly affected by the development of large dams in upstream region of Mekong River. This paper aims at basic study about the large scale flood inundation of Cambodia using by CAESAR-Lisflood. CAESAR-Lisflood is a geomorphologic / Landscape evolution model that combines the Lisflood-FP 2d hydrodynamic flow model (Bates et al, 2010) with the CAESAR geomorphic model to simulate flow hydrograph and erosion/deposition in river catchments and reaches over time scales from hours to 1000's of years. This model is based on the simplified full Saint-Venant Equation so that it can simulate the interacted flow of between Mekong River and Tonle Sap Lake especially focusing on the flow direction change of Sap River by season.

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