Transactions of the Korean Society of Mechanical Engineers B (대한기계학회논문집B)

The Korean Society of Mechanical Engineers (대한기계학회)
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Effects of Geometric and Flow Conditions on 3-dimensional Hydrodynamic Focusing

3 차원 유체역학 집속에 대한 채널 형상 및 유동 조건의 매개변수 연구

  • Han, Kyung-Sup (School of Mechanical Engineering, Chung-Ang University) ;
  • Kim, Dong-Sung (School of Mechanical Engineering, Chung-Ang University)
  • 한경섭 (중앙대학교 기계공학부) ;
  • 김동성 (중앙대학교 기계공학부)
  • Published : 2010.01.01
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Abstract

In our previous work, 3-dimensional hydrodynamic focusing microfluidic device (3D-HFMD) has been developed with the help of locally increased aspect ratio of thickness to width without any horizontal separation wall. In this study, we have investigated 3-dimensional hydrodynamic focusing behaviors inside the 3D-HFMD according to the various geometric and flow conditions. The parametric study has been extensively carried out for the effects of geometric and flow conditions on 3-dimensional hydrodynamic focusing with both 3D-HFMD and previous microfluidic device design based on three-dimensional computational fluid dynamics (CFD) simulations. The CFD simulations suggested the proper design window of channel geometry and flow conditions.

최근 본 연구그룹은 국소적인 종횡비 증가를 기반으로 수평 분리벽 없이 검체의 3 차원 집속을 구현하는 3 차원 유체역학 집속 미세유체 장치(3D-HFMD)를 제안한 바 있다. 본 논문에서는, 다양한 형상 및 유동 조건에 따른 3D-HFMD 의 3 차원 유체역학 집속 거동 영향에 대한 연구를 수행하였다. 이에 3 차원 전산유체역학(CFD) 시뮬레이션을 통해, 형상 및 유동 조건 변화에 대한 기존의 미세유체 장치와 본 연구 그룹이 제안한 3D-HFMD의 3 차원 유체역학 집속의 매개변수 연구를 수행하였다. 수행된 CFD 시뮬레이션 결과를 바탕으로 3 차원 집속을 위한 채널 형상 디자인 및 유동 조건을 제안하였다.

Keywords

References

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