• Title/Summary/Keyword: 3 stage

검색결과 17,689건 처리시간 0.05초

자궁내막증 환자에서 혈청 CA 125치 동태에 관한 연구 (Serum CA 125 Levels in Patients with Endometriosis)

  • 이진용;윤병구;최영민;신창재;장윤석
    • Clinical and Experimental Reproductive Medicine
    • /
    • 제17권2호
    • /
    • pp.101-106
    • /
    • 1990
  • Serum CA 125 was measured with immunoradiometric assay in fourty-one patients of endometriosis Serum CA 125 levels (Mean ${\pm}$ SEM, U/ml)in patients with endometriosis were 13.8${\pm}$3.3 in stage I , 17.3${\pm}$3.0 in stage II, 23.4${\pm}$4.9 in stage III, and 64.5${\pm}$13.2 in stage IV, which showed increment according to the stage of endometriosis. Serum levels in stage IV only were significantly elvated than those in control (15.3${\pm}$2.2), and those in advanced stage(III and IV ; 47.1${\pm}$9.5)were significantly higher than those in earlier stages (15.9${\pm}$2.2)and control. The assay revealed a sensitivity of 31.7% and the frequency of elevated levels (> 30.3 U/ml)in stage I, II, III and IV was 9. 1%, 18.8%,33.3%, and 87.5% respectively. Sensitivity in advanced stage was higher than that in earlier stage (64.3% vs. 14.8%). There data suggest that serum CA 125 assay might be a useful diagnostic tool in the advanced stage of endometriosis.

  • PDF

폐암의 임상적 고찰과 장기 성적 (Long Term Results and Clinical Evaluation of Lung Cancer)

  • 장재현
    • Journal of Chest Surgery
    • /
    • 제26권6호
    • /
    • pp.463-469
    • /
    • 1993
  • From May 1986 to May 1992, 72 patients were diagnosed and operated for primary lung cancer, among them 65 patients were clinically evaluated at the department of Thoracic & Cardiovascular Surgery, Masan Koryo General Hospital. 1. There were 52 males 13 females[M:F=4:1], and 5th, 6th decade of life[72%] was peak incidence. 2. The preoperative diagnosis and its positive rate were sputum cytology 35%, bronchoscopy 47%, pleural effusion cytology 80%, and pleural biopsy 50%. 3. The classification histologic types were squamous cell cancer 71%, adenocarcinoma 17%, undifferentiated cell carcinoma 4.6%, and staging classification were Stage I 31%, Stage II 22%, Stage IIIa 26%, and Stage IIIb 20%. 4. The operative methods were lobectomy 52%, pneumonectomy 36%, and open biopsy 12%, and operability was 89%, resectability was 88%. 5. The postoperative complications developed 13 patients[22%], and operative mortality was 5%. 6. The overall actuarial survival rate was 1year 70%, 2year 42%, 3year 32%, 4year 26%, and 5year 22%, according to Stage 5year survival rate was Stage I 37%, Stage II 22%, Stage IIIa 3year 12%, Stage IIIb 2year 23%. And according to operative method lobectomy 23%, pneumonectomy 19%.

  • PDF

지식경영 프로세스 능력 모델 개발 연구 (A Study on the Process Capability Model of Knowledge Management)

  • 김현수
    • Asia pacific journal of information systems
    • /
    • 제11권3호
    • /
    • pp.23-42
    • /
    • 2001
  • Recently, knowledge management becomes a core management tool for efficient and effective organizations. However, there are little known researches on measuring knowledge management level. The objective of this paper is to develop a process capability model for knowledge management of an organization. We developed 5 stage process capability model for knowledge management. The 1st stage is the initial stage where no significant knowledge management activity is performed. The 2nd stage is the performed stage where planning and tracking activities are performed on organization level. The 3rd stage is the established, and the 4th stage is the predictable stage where processes and results of knowledge management can be predictable. Final stage is the optimizing stage where knowledge management process is continuously improved at an organizational level. We surveyed 37 korean companies to test the validity of the proposed stage model. Statistical tests show that the developed stage model of knowledge management is valid and sound in general conditions. The result of this study on process capability model can be a solid stepping stone for future works in this area.

  • PDF

원발성 폐암의 임상적 고찰 (Clinical Evaluation of Lung Cancer)

  • 박해문
    • Journal of Chest Surgery
    • /
    • 제24권1호
    • /
    • pp.72-82
    • /
    • 1991
  • From May 1978 to Sep. 1990, 106 patients who had been diagnosed as primary lung cancer and operated on at the Department of Thoracic & Cardiovascular Surgery, Han Yang University, were clinically evaluated. 1. The peak incidence of age was 5th decade of life[37.7%] and 6th decade[29.2%]. Male to female ratio was 3.8: l. 2. Most of symptoms were respiratory, which were cough, chest pain, hemoptysis, and asymptomatic cases were 2.9%. 3. Histopathologic classifications were squamous cell carcinoma[53.7%], adenocarcinoma [23.8%], bronchioloalveolar cell carcinoma[6.6%], undifferentiated large cell carcinoma[6.6%], small cell carcinoma[3.8%], adenosquamous carcinoma[3.8%] and others[1.8%]. 4. Methods of operation were pneumonectomy 49.1%[52cases], lobectomy 21%[22cases] bilobectomy[6cases], lobectomy with wedge resection[3cases], exploration 21.9%[23cases], and resectability was 78.3%. 5. Staging classifications were Stage I [22.6%], Stage II [11.3%], Stage IIIa[42.6%], Stage IIIb[21.7%] and Stage lV[1.6%]. Resectability by Stage; Stage I was 100%, II 100%, IIIa 84.4% and IIIb 30.4%. 6. Causes of most of inoperable cases were invasion of mediastinal structures and diffuse chest wall, and others were contralateral lymph node invasion and malignant pleural effusion. 7. Operative mortality was 6.7% which caused by arrhythmia, sepsis, pulmonary edema, and radiation pneumonitis. 8. On the long term follow up of the resectable cases, overall 1 year survival rate was 58.5 %, 2 year 39%, and 5 year 19.5%. Five year survival rate was 40% in Stage I, 25% in Stage II and 11.7% in Stage Illa. As for the method of operation, the higher 5 year survival rate was observed in lobectomies[33.3%] than in pneumonectomies[10.3%].

  • PDF

3차원 기로틴 3단계 자재절단 방법에 관한 연구 (A study on the 3-stage 3-dimensional guillotine cutting-stock problem)

  • 김상열;박순달
    • 한국경영과학회:학술대회논문집
    • /
    • 대한산업공학회/한국경영과학회 1996년도 춘계공동학술대회논문집; 공군사관학교, 청주; 26-27 Apr. 1996
    • /
    • pp.276-279
    • /
    • 1996
  • This paper deals with the method providing an exact solution to the 3-dimensional guillotine cutting stock problem. We suggest a 3-stage sutting method using the property that cubic material has to be cut into 2-dimensional planes firstly. This method requires more stocks that the general guillotine cutting methods but can save work force. By using the 1-dimensional dynamic programming, we reduce the computational time and the memory requirement in the 3-stage guillotine cutting method.

  • PDF

관절경적 감압술에 의한 견봉하 충돌증후군의 치료 (Arthroscopic Decompression of Subacromial Impingement Syndrome)

  • 김성재;김범수;최남홍
    • 대한견주관절학회:학술대회논문집
    • /
    • 대한견주관절학회 1995년도 학술대회
    • /
    • pp.13-13
    • /
    • 1995
  • The authors performed the arthroscopic decompression and cuff debridement on 47 cases in 45 consecutive patients with either stage II or stage III impingement syndrome from July 1990 to January 1994. The summarized results are as follows. 1. 47 cases in 45 consecutive patients had arthroscopic decompression for the subacromial impingement syndrome. 2. There were 31 males and 14 females and the mean age was 40 years for men and 46years for women. 3. The follow up duration was from 3 years 9 months to 1 year (average 2 years 1month). 4. Among 47 cases, 19 cases were found to have no cuff tear (stageII) 13 cases partial thickness cuff tear (stage IIIa) 10 cases complete tear on cuff less than 3 cm long (stage IIIb) and 5 cases complete tear on cuff more than 3 em in length (stage IIIc). 5. The arthroscopic subacromial decompression and rotator cuff debridement was a good treatment method in stage II and stage IIIa and stage IIIb. in the case of stage IIIc rotator cuff tear, it was useful for pain relief and improvement of shoulder function.

  • PDF

무극광산(無極鑛山) 삼형제맥(三兄弟脈)의 금은광화작용(金銀鑛化作用) (Gold and Silver Mineralization of Samhyungje Vein, the Mugeug Mine)

  • 박희인;강성준
    • 자원환경지질
    • /
    • 제21권3호
    • /
    • pp.257-268
    • /
    • 1988
  • The Mugeug gold deposits is consisted of more than fourteen gold and silver-bearing quartz veins emplaced in Mesozoic granodiorite mass. In the Samhyungje vein, one of the representative vein in the mine, six stages of mineralizatidns are recognized: Stage I, deposition of base-metal sulfides and gray quartz; stage II, deposition of base-metal sulfides, electrum and white quartz with pinkish tint; stage m, deposition of base-metal sulfides and dark gray quartz; stage N, deposition of native silver, argentite, Ag-tetrahedrite, polybasite, arsenpolybasite and quartz; stage V, deposition of nearly barren quartz; stage VI, deposition of transparent quartz veinlets with minor pyrite. Ag contents of electrum increase steadily from stage II to stage N; 57.25-61.44 atom. % for stage II, 62.85-69.66 atom. % for stage m, 69.79-74.12 atom. % for stage N. Homogenization temperatures of fluid inclusions are as follows; stage II, from $194^{\circ}$ to $287^{\circ}C$; stage V, from $137^{\circ}$ to $171^{\circ}C$, stage VI, from $192^{\circ}$ to $232^{\circ}C$. Salinities of fluid inclusions range from 3.7 to 7.9 wt.% equivalent NaCl in stage II and from 0.8 to 4.3 wt.% equivalent Nael in stage V. Ore mineralogy suggest that temperature and sulfur fugacity declined steadily from $290^{\circ}$ to $150^{\circ}C$ and from $10^{-10.5}$ to $10^{-19.0}$atm. through stage II into stage N. Fluid pressure during stage II inferred from data of mineral assemblages and fluid inclusions is 370bar.

  • PDF

드로잉 가공에서 다이패드의 독립형과 일체형 구조가 제품 두께에 미치는 영향에 관한 연구 (A Study on the Influence of the Integrated Structure and Independent of the Die Pad on the Products thickness in the Drawing Process)

  • 이춘규;남승돈
    • 대한안전경영과학회지
    • /
    • 제17권2호
    • /
    • pp.235-240
    • /
    • 2015
  • Using a progressive die of the multi-stage drawing product, It was experiments for the Influence of the Products Roundness on the die pad process Safety die model, obstacle countermeasure research safety die design When the die pad is independent structure, Sidewall thickness of the inside 2stage, 3stage, 4stage of the product is thicker, the thickness of the inside 1stage and the bottom is thinner. it was become unstable beacuse the inside 1stage related to the Products Roundness is thinner. When the die pad is Integrated structure, Sidewall thickness of the inside 1stage, 2stage of the product is thicker, and Sidewall 3stage and 4stage was a thin. it was become unstable beacuse the inside 3stage related to the Products Roundness is thinner. Therefore, The appropriate combination of and integrated independent is required for each process.

Production of 3-Ketosteroid-delta-1-Dehydrogenase by a Two-stage Continuous Culture

  • Ryu, D.Y.;Lee, B.K.;Thoma, R.W.
    • 한국미생물·생명공학회지
    • /
    • 제2권1호
    • /
    • pp.29-35
    • /
    • 1974
  • We have studied the applicability of the principles and inherent advantages of the two-stage dontinuous uclture technique to an enzyme process for the purpose of improving and optimizing the productivity of 3-ketosteroid-delta-1-dehydrogenase. By using a two-stage continuous culture system, the growth st ageand enzyme produdtion stage are separated. In each stage an optimal set of toperaing conditions was determined, and this was tested for feasibility for the period of 10 days. During this period, at least 70% of the maximum enzyme productivity could be maintained. The important design parameters studied are: (1) optimal specific growth rate in the first stage which corresponds to the maximal cell productivity, (2) the optimal dilution rate in the second stage which in turn determines the size of second stage fermentor and the mean residence time of cells in the second stage, (3) cell concentration in both stages, add (4) the specific enzyme productivity and enzyme productivity of the second stage. In addition, by using two-stage continuous culture system we have been able to reduce or eliminate the effect of catabolite repression due to high medium concentration and the adverse effect of the solvent used to dissolve the inducer. We have found the balance between the opposing effects of induction and repression in the second stage judging from the observation that the enzyme productivity goes through a maximum.

  • PDF

한국 여아의 성 성숙 단계별 체구성과 영양소섭취 실태 (Comparison of Dietary Intakes and Body Composition by Tanner Stages in Korean Girls)

  • 이선희;백희영;홍경의;정효지
    • Journal of Nutrition and Health
    • /
    • 제37권7호
    • /
    • pp.566-575
    • /
    • 2004
  • To compare the dietary intakes and body composition in the stage of puberty, this study was conducted with 360 girls aged 9 to 12 years in Seoul Korea. Girls's general information and 3-day diet records were collected, fat mass was measured by Inbody 3.0, bone mass at right calcaneus was measured by PIXI and pubertal development was self-assessed by picture of Tanner stages. The results are as follows: Girls who had breast development were 79.7% and 15.8% had pubic hair development. Mean of BMI, BMC and BMD were significantly higher at breast stage3+(19.6 kg/$m^2$, 1.62 kg, 0.47 g/$\textrm{cm}^2$) than at the breast stage2 (18.2 kg/$m^2$, 1.47 kg, 0.44 g/$\textrm{cm}^2$) or breast stage1(16.3 kg/$m^2$, 1.32 kg, 0.39 g/$\textrm{cm}^2$) (p < 0.001). Percent body fat of breast stage1, 2, and 3+ were 19.7%, 23.1%, 25.3% respectively and significantly increased during the puberty (p < 0.001). The mean of energy intake was 1629 kcal in stage1, 1664 kcal in stage2 and 1577 kcal in stage3+ showed significant difference in the breast stages (p < 0.05). Energy adjusted sodium intakes and crude fiber intakes were significantly higher in breast stage3 + than other breast stages. For zinc and iron, proportions of subjects with intake levels less than 75% of Korean RDA was over 40% and significantly higher in breast stage3+ than other stages (p < 0.05) ; for protein and vitamin E, the proportions of subjects with intake levels more than 125% RDA was significantly higher in the stage 1. The nutrient adequacy ratio (NAR) for protein and phosphorous was significantly lower in breast stage3+ than other stages. The food groups of seed and nut were 4.7 g/day, 2.3 g/day, 1.8 g/day, respectively, and was significantly higher in breast stage 1. In summary, mean of BMI, BMD, BMC and percent of body fat were increased with pubertal development, and those who had higher breast developmental stage showed a lower amount of consumption level in energy, seeds and nuts, and also showed a higher amount of consumption level in energy adjusted sodium and fiber among Korean girls.