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An Empirical Comparison and Verification Study on the Containerports Clustering Measurement Using K-Means and Hierarchical Clustering(Average Linkage Method Using Cross-Efficiency Metrics, and Ward Method) and Mixed Models (K-Means 군집모형과 계층적 군집(교차효율성 메트릭스에 의한 평균연결법, Ward법)모형 및 혼합모형을 이용한 컨테이너항만의 클러스터링 측정에 대한 실증적 비교 및 검증에 관한 연구)

  • Park, Ro-Kyung
    • Journal of Korea Port Economic Association
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    • v.34 no.3
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    • pp.17-52
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    • 2018
  • The purpose of this paper is to measure the clustering change and analyze empirical results. Additionally, by using k-means, hierarchical, and mixed models on Asian container ports over the period 2006-2015, the study aims to form a cluster comprising Busan, Incheon, and Gwangyang ports. The models consider the number of cranes, depth, birth length, and total area as inputs and container twenty-foot equivalent units(TEU) as output. Following are the main empirical results. First, ranking order according to the increasing ratio during the 10 years analysis shows that the value for average linkage(AL), mixed ward, rule of thumb(RT)& elbow, ward, and mixed AL are 42.04% up, 35.01% up, 30.47%up, and 23.65% up, respectively. Second, according to the RT and elbow models, the three Korean ports can be clustered with Asian ports in the following manner: Busan Port(Hong Kong, Guangzhou, Qingdao, and Singapore), Incheon Port(Tokyo, Nagoya, Osaka, Manila, and Bangkok), and Gwangyang Port(Gungzhou, Ningbo, Qingdao, and Kasiung). Third, optimal clustering numbers are as follows: AL(6), Mixed Ward(5), RT&elbow(4), Ward(5), and Mixed AL(6). Fourth, empirical clustering results match with those of questionnaire-Busan Port(80%), Incheon Port(17%), and Gwangyang Port(50%). The policy implication is that related parties of Korean seaports should introduce port improvement plans like the benchmarking of clustered seaports.

Expression of Immortalization-upregulated Proteins-2 (IMUP-2) in Placenta (태반 내 Immortalization-upregulated Proteins-2 (IMUP-2) 발현)

  • Jeon, Su-Yeon;Lee, Hyun-Jung;Jung, Hyun-Min;Kim, Jin-Kyeoung;Kim, Gi-Jin
    • Clinical and Experimental Reproductive Medicine
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    • v.36 no.3
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    • pp.163-174
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    • 2009
  • Objectives: Members of the immortalization-upregulated protein (IMUP) family are nuclear proteins implicated in SV40-mediated immortalization and cellular proliferation, but the mechanisms by which their expression is regulated are still unknown in placenta. To investigate to expression and functions of IMUPs in placenta, we conducted to compare IMUPs expression in normal and preeclamptic placenta tissues and analyzed the function of IMUP-2 in HTR-8/SVneo trophoblast cells after IMUP-2 gene transfection. Methods: The expression of IMUPs was analyzed in placental tissues from the following groups of patients (none underwent labor): 1) term normal placenta (n=15); 2) term with preeclamptic placeneta (n=15); and 3) pre-term with preeclamptic placenta (n=11) using semi-quantitative RT-PCR, RNA in situ hybiridization, immunohistochemistry, and Western blot. In order to evaluate the function of IMUP-2 in HTR-8/SVneo trophoblast cells, IMUP-2 plasmids were transfected into HTR-8/SVneo trophoblast cells for 24 hours. Results: We observed that IMUPs are mainly expressed in the syncytiotrophoblasts and syncytial knot of placental villi. The expression of IMUP-1 was not differences between normal and preeclamptic placenta tissues. However, IMUP-2 expression was significantly higher in preterm preeclamptic placenta tissues than in normal placenta tissues without labor (p<0.001). Furthermore, we confirmed overexpression of IMUP-2 induced apoptosis in HTR-8/SVneo trophoblast cells through up-regulation of pro-apoptotic proteins. Conclusions: These results suggest that the expression of IMUP-2 is involved in placental development as well as increased IMUP-2 expression is associated with preeclampsia through the inducing of trophoblast apoptosis.

Comparison of Growth Characteristics of Creeping Bentgrass(Agrostis palustris Huds.) Cultivars in Summer (하절기 크리핑 벤트그래스의 품종별 특성비교)

  • Tae, Hyun-Sook;Lee, Hyung-Seok;An, Kil-Man;Kim, Jong-Bo
    • Asian Journal of Turfgrass Science
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    • v.20 no.2
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    • pp.147-156
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    • 2006
  • This study was initiated to evaluate the growth characteristics of seven creeping bentgrass cultivars in summer, 'Penncross' showed the worst visual quality, whereas 'Penn A-4' and 'Crenshaw' the best quality. 'Putter', which was maintained a fair quality during the test period, was regarded as a good cultivar because of no significant variation in summer as compared to the other caltivars. 'Crenshaw',' L-93' and 'Penn A-4' were greater in chlorophyll content and 'Penncross' lowest during the summer. Also, 'SR1020' had a low content of chlorophyll. 'Putter' greatly increased in chlorophyll content after fertilization. The highest shoot density($19.3/cm^2$) was found with 'L-93' in early August, followed by 'Crenshaw', 'Penn A-4', 'Putter', 'Dominant', and 'SR1020' in that order. However, 'Penncross' was lowest($15.7/cm^2$). As for a root length, 'L-93' was longest, being over an average 5.5cm. 'Penn A-4' and 'Putter' also showed good result in root growth. However, the root length considerably decreased with 'SR1020', 'Penncross' and 'Dominant' in summer. Brown patch was a serious disease for the most cultivars, except 'Penncross'. 'Dominant' had the most serious damage. 'Putter', 'L-93', 'Crenshaw', 'SR1020', and 'Penn A-4' were also greater in damage over the others. In regards of algae occurrence in summer, 'Penn A-4' had the least damage, while 'Dominant' the greatest. In conclusion, 'Crenshaw', 'Penn A-4' and 'L-93' were the best cultivars in terms of summer growth. Conversely, 'Penncross' was the poorest one. However, this study was conducted under the conditions of one-year old green. Accordingly, in-depth experiment should be done over several years to elucidate the characteristics of growth for the wide range of creeping bentgrass cultivars during the summer.

Comparison of internal and marginal fit of crown according to milling order in a single machinable wax disc (단일 절삭가공용 왁스 디스크 내에서 순차적 절삭가공 순서에 따른 크라운의 내면 및 변연 적합도 비교)

  • Song, Jun-Beom;Lee, Jonghyuk;Ha, Seung-Ryong;Choi, Yu-Sung
    • The Journal of Korean Academy of Prosthodontics
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    • v.59 no.4
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    • pp.395-404
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    • 2021
  • Purpose. The purpose of present study was to evaluate the effect of changing structural stability of wax disc on the fit of prosthesis when the milling proceeded in order. Materials and methods. Prepared maxillary left first molar was used to fabricate a Ni-Cr alloy reference model. This was scanned to design crown and then wax pattern was milled, invested and cast to fabricate prosthesis. The wax patterns located in a row centrally within a single wax disc were set into a total of five groups ranging from WM1 group that was first milled to WM5 group that was last milled and the number of each group was set as 10. Silicone replica technique was used to measure the marginal gap, axial internal gap, line angle internal gap, occlusal internal gap. Data was evaluated with one-way ANOVA with significance level set at α = .05 and then Tukey HSD test was conducted for post analysis. Results. Marginal gap measured in each group, it was 40.41 ± 2.15 ㎛ in WM1 group, 40.44 ± 2.23 ㎛ in WM2 group, 39.96 ± 2.25 ㎛ in WM3 group, 39.96 ± 2.48 ㎛ in WM4 group, and 40.57 ± 2.53 ㎛ in WM5 group. No significant difference was found between groups. The significant difference between the groups was also not found in the axial internal gap, line angle internal gap, and occlusal internal gap. Conclusion. Internal and marginal fit of single crown to the sequential order of milling processing in the single machinable wax disc did not seem to be affected by the sequence.

Analysis of Genetic Diversity and Population Structure for Core Set of Waxy and Normal Maize Inbred Lines using SSR Markers (SSR 분자마커를 이용한 찰옥수수 및 종실용 옥수수 자식계통들의 핵심집단에 대한 유전적 다양성 및 집단구조 분석)

  • Sa, Kyu Jin;Kim, Jin-Ah;Park, Ki Jin;Park, Jong Yeol;Goh, Byeong Dae;Lee, Ju Kyong
    • Korean Journal of Breeding Science
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    • v.43 no.5
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    • pp.430-441
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    • 2011
  • Maize is divided into two types based on the starch composition of the endosperm in the seed, normal maize(or non-waxy maize) and waxy maize. In this study, genetic diversity and population structure were investigated among 80 waxy maize and normal inbred lines(40 waxy maize inbred lines and 40 normal maize inbred lines) using 50 SSR markers. A total of 242 alleles were identified at all the loci with an average of 4.84 and a range between 2 and 9 alleles per locus. The gene diversity values varied from 0.420 to 0.854 with an average of 0.654. The PIC values varied from 0.332 to 0.838 with an average of 0.602. To evaluate the population structure, STRUCTURE 2.2 program was employed to confirm genetic structure. The 80 waxy and normal maize inbred lines were separated with based on the membership probability threshold 0.8, and divided into groups I, II and admixed group. The 13 waxy maize inbred lines were assigned to group I. The 45 maize inbred lines including 7 waxy maize inbred lines and 38 normal maize inbred lines were assigned to group II. The 22 maize inbred lines with 20 waxy maize inbred lines and 2 normal maize inbred lines were contained in the admixed group. The cluster tree generated using the described SSR markers recognized three major groups at 31.7% genetic similarity. Group I included 40 waxy maize inbred lines and 11 normal maize inbred lines, and Group II included 27 normal maize inbred lines. Group III consist of only 2 normal maize inbred lines. The present study has demonstrated the utility of SSR analysis for the study of genetic diversity and the population structure among waxy and normal maize inbred lines. The information obtained from the present studies would be very useful for designing efficient maize breeding programs in Maize Experiment Station, Kangwon Agricultural Research and Extension Services.

The Distributional Patterns of Silla Burial Grounds and the Character of Outer Coffin Tombs in Jjoksaem Site, Gyeongju (쪽샘유적 신라고분 분포양상과 목곽묘의 성격)

  • Yun, Hyoung-Jun
    • Korean Journal of Heritage: History & Science
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    • v.50 no.4
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    • pp.198-221
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    • 2017
  • The Jjoksaem site is the eastern sector of Daereungwon Ancient Tomb Complex, Gyeongju(the 512th Historic site) called Wolseong North Burial Ground in academic community. The excavation and research of this site was conducted from 2007 to 2015, with the purpose of basic data offering for the restoration of Silla tumuli and development of ancient tomb park. As a result of the investigation, more than 700 new tombs were discovered except the 155 tumuli founded in the Japanese colonial era. Moreover, more than 70 percent of the smaller tombs, such as outer coffin tombs, were discovered here. There are four characteristics of outer coffin tombs in Jjoksaem site. First, it is recognized the Gyeongju-styled outer coffin tombs have a long rectangular shape, distinct from Gimhae-styled outer coffin tombs in a rectangular shape. Second, they are divided into three groups by the size of the grave area. This is indirectly related to the rank and the status of the buried person. Third, these tombs began to be constructed at the end of the 3rd century before the time of wooden chamber tombs covered by stone and earthen mound. They were ruined because of the new tombs constructed at the period of Maripgan. This reflects that the identity of the former tombs was not respected by the communities in the later generations. Outer coffin tombs were consistently made to the end of the era of wooden chamber tombs covered by stone and earthen mound. Lastly, the area of burial ground of outer coffin tombs is limited by wooden chamber tombs covered by stone and wooden mounds. Otherwise, the location of the burial ground for the deceased is limited by the status of the deceased. The idea that wooden chamber tombs covered by stone and earthen mound are located on the above ground turns out to be incorrect. In Jjoksaem site, there is little difference between the height of the circular burial protection stone and the height of the digging lines of the other tombs. In the case of No.44 tumulus, the lowest step of the circular burial protection stones is lower than those of the other tombs and tumuli. Research of outer coffin tombs at Jjoksaem site will be to suggest important academic data about the changing period from Saroguk, as the head of chiefdom union, to Silla, as state.

Validation of initial nutrition screening tool for hospitalized patients (입원 환자용 초기 영양검색도구의 타당도 검증)

  • Kim, Hye-Suk;Lee, Seonheui;Kim, Hyesook;Kwon, Oran
    • Journal of Nutrition and Health
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    • v.52 no.4
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    • pp.332-341
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    • 2019
  • Purpose: Poor nutrition in hospitalized patients is closely linked to an increased risk of infection, which can result in complications affecting mortality, as well as increased length of hospital stay and hospital costs. Therefore, adequate nutritional support is essential to manage the nutritional risk status of patients. Nutritional support needs to be preceded by nutrition screening, in which accuracy is crucial, particularly for the initial screening. To perform initial nutrition screening of hospitalized patients, we used the Catholic Kwandong University (CKU) Nutritional Risk Screening (CKUNRS) tool, originally developed at CKU Hospital. To validate CKUNRS against the Patient-Generated Subjective Global Assessment (PG-SGA) tool, which is considered the gold standard for nutritional risk screening, results from both tools were compared. Methods: Nutritional status was evaluated in 686 adult patients admitted to CKU Hospital from May 1 to July 31, 2018 using both CKUNRS and PG-SGA. Collected data were analyzed, and the results compared, to validate CKUNRS as a nutrition screening tool. Results: The comparison of CKUNRS and PG-SGA revealed that the prevalence of nutritional risk on admission was 15.6% (n = 107) with CKUNRS and 44.6% (n = 306) with PG-SGA. The sensitivity and specificity of CKUNRS to evaluate nutritional risk status were 98.7% (96.8 ~ 99.5) and 33.3% (28.1 ~ 39.0), respectively. Thus, the sensitivity was higher, but the specificity lower compared with PG-SGA. Cohen's kappa coefficient was 0.34, indicating valid agreement between the two tools. Conclusion: This study found concordance between CKUNRS and PG-SGA. However, the prevalence of nutritional risk in hospitalized patients was higher when determined by CKUNRS, compared with that by PG-SGA. Accordingly, CKUNRS needs further modification and improvement in terms of screening criteria to promote more effective nutritional support for patients who have been admitted for inpatient care.

Skin Coloration and Endogenous Hormonal Changes of 'Kyoho' Grape by High Temperature at Veraison (변색기 고온에 의한 포도 '거봉'의 과피 착색 및 내생 호르몬 변화)

  • Ryu, Suhyun;Cho, Jung-Gun;Jeong, Jae Hoon;Lee, Seul-Ki;Han, Jeom Hwa;Kim, Myung-Su
    • Journal of Bio-Environment Control
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    • v.28 no.3
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    • pp.234-242
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    • 2019
  • We analyzed the anthocyanin accumulation, abscisic acid (ABA), gibberellic acid (GA) contents and metabolic genes expression in berry skins under high temperature (High T) at veraison, in order to investigate the cause of bad coloration of 'Kyoho' grape due to High T in summer season. The coloration of 'Kyoho' grapes was stopped by High T for 10 days from veraison, and the fruit quality was not affected except skin color. Total anthocyanin of skins was decreased by High T treatment and malvidin and peonidin were decreased compared to control. In berry skins, ABA content did not decrease by High T treatment, but it was rather higher than that of control. GA content was increased about two times compared to the control after 10 days of High T treatment, which caused decreased ratio of ABA/GA. Analysis of expression of anthocyanin biosynthetic genes showed that the early biosynthetic genes were not affected by High T and the expression of UFGT was decreased by temperature treatment. ABA biosynthetic gene expressions were not affected by High T and the expression of GA20ox1 and GA2ox1/2, which are known to regulate the biosynthesis and inactivation of GA, were increased and decreased by High T, respectively. Therefore, the bad coloration of 'Kyoho' grapes under the High T at veraison was due to inhibition of anthocyanin biosynthesis of skin, and it was suggested that the anthocyanin biosynthesis was controlled by the ratio of ABA and GA rather than ABA content.

Evaluation of Dental Hygienist Job Validity according to Judgment Standard of Medical Practice in Medical Law (의료행위 기준에 따른 치과위생사 직무 타당도 평가)

  • Bae, Soo-Myoung;Shin, Sun-Jung;Lee, Hyo-Jin;Shin, Bo-Mi
    • Journal of dental hygiene science
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    • v.18 no.6
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    • pp.357-366
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    • 2018
  • The purpose of this study was to evaluate the validity of dental hygienist job according to judgment standard of medical practice in medical law. In this study, we conducted a self-administered questionnaire survey to evaluate the validity of dental hygienist job for 12 professors of dental college in Gangneung-Wonju National University from November 10 to 20, 2017. We investigated whether the dental hygienist job conforms to the three criteria of medical practice such as disease prevention and treatment, patient care, and health hazard. The response rates were scored and classified into four categories according to the final score. As a result of this study, dental hygienist job are classified into four categories according to judgment standard of medical practice. The higher the level of the category, the higher the degree of difficulty, and the higher the level of expertise and skills required. More than 50% of respondents answered that measuring the gingival pocket, bleeding on probing, professional tooth cleaning, oral health education, counseling after dental treatment are all three criteria for medical treatment. And these were classified into Level 4 group which requires the difficulty and expertise in the final score 4.3. It is necessary to develop and utilize standardized guidelines on the level of knowledge, education, and qualification standards required for dental practice in order to effectively allocate work among the dental personnel while ensuring the health rights of patients in the dental clinic field in Korea. In addition, there is a need to evaluate the various aspects of cost effectiveness, dental health service productivity, and health promotion contribution to dental hygienist jobs, And based on this evidence, it is necessary to continue to expand and adjust the dental hygienist job and to reorganize the dental workforce system.