• Korean Journal of Clinical Laboratory Science
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• v.51 no.3
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• pp.329-335
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• 2019

Annually, millions of children die from respiratory virus infections. Human rhinovirus (HRV) is a causative agent of severe respiratory infections in young, elderly, and asthmatic patients with weak immunity. In this study, 9,010 respiratory virus specimens were collected from January 2012 to December 2018 at Dankook University Hospital, Cheonan and examined by real-time reverse transcription polymerase chain reaction. Twelve respiratory viruses were detected. The mean detection rate was 21.3% (N=1,920/9,010), and the mean age of HRV-positive patients was 6.5 years (median age: 1.6 years, range: 0.0~96.0). The detection rate was the highest in July (32.4%) and the lowest in February (8.3%). When the detection rate was analyzed by age group, the detection rate was the second highest in patients aged 10~19 years. The co-infection rate of HRV was 35.3%, and the most common combination was with Adenovirus. Respiratory virus infections are known to occur in children and elderly people with weak immunity. However, in this study, the detection rate was second highest in patients aged 10~19 years. Indeed, the detection rate in this age group was more than 15%, except in January and February. These results suggested that steady-state studies on the infection patterns of HRV are required.

• Journal of Chest Surgery
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• v.29 no.4
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• pp.373-380
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• 1996

Prevention of thromboembolism is the most important task in the development of bioconpatible small caliber artificial vascular graft. In normal vessels, vascular endothelial cells maintain homeosatsis by secreting numerous factors. The aim of this study is to develope a method which Improves biocompatibility of small caliver polyurethane graft using endothelial cell culture technique, and ev luate the efTectiveness of extracelluar matrix for endothelization which was produced by cultured fibroblast. Methods ; Multiporous polyurethane tube of 3 mm diameter, 0.3 mm thickness was manufactured for vascular graft. Three mongrel dogs were intubated and internal jugular veins removed. Extracelluar matrix produced by cultured flbrobast which was obtained from dog's internal jugular vein were coated to the polyurethane graft. Then, endothelial cells extracted from Jugular vein were cultured and fixed on the extracelluar matrix layer of vascular graft. Endothelial cell coated vascular grafts were implanted to the carotid arteries of experimental dogs as interposed autograft. Implanted grafts were removed after 3 and 6 weeks. As a control, PTFE graft was interposed on carotid artery. These experiments demonstrated that extracelluar matrix produced by fibroblast can afford a base for endothelial cell linings of polyurethane graft. Although thrombosis were developed on autografted en othelial cell coated graft, 33% opening was noticed, and showed less adhesion to adjacent tissue layer. These findings suggest that fiboblast produced extracelluar matrix which can be used for edothelial cell lining vascular graft, and by improving the cultured endothelial cell function, there will be a new modality for reducing thrombosis on small vascular graft.

• Pediatric Infection and Vaccine
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• v.4 no.2
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• pp.240-256
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• 1997

Purpose: To evaluate the hepatitis B vaccination program which has been conducted since 1980, Korea. Methods: This study was carry out self reported questionnaire and serologic test covering 2,072 elementary school students who were born between 1980 and 1987, selected by cluster sampling. The HBV serologic markers (HBsAg, Anti-HBs and Anti-HBc) were tested by radioimmunoassay (RIA). The contents of questionnaire include demographic data of students and parents, vaccination status, vaccination frequency, vaccination age, past history of mother's HBV test. Results: 1) The HBsAg positive rates by sex showed 3.7% for male and 2.7% for female, representing an average rate of 3.4%. The HBsAg positive rates by age group showed 5.6% for 13 years and l.5% for 6 years, representing a tendency of lowering rate as ages being younger. 2) The pre-natal HBV test rate was 10.2%, while post-natal HBV test rate was 42.5%. The test showed that the parents' educational level being higher than others, the pre- and post-natal HBV test showed higher rates. In case the fathers occupation being office worker, the post-natal HBV test showed a higher rate compared with other occupation. 3) Overall vaccination rate was 82.6%, complete vaccination rate 69.8%, booster injection rate 42.8%. The vaccination rate, complete vaccination rate and booster injection rate increased as the age being younger. If the educational level of parents were higher, the vaccination rate, complete vaccination rate and booster injection rate showed higher rates. Younger students showed younger vaccination age, and higher educational background of family showed younger vaccination ages. 4. With regard to positive rate of HBV markers by vaccination age, HBsAg and Anti-HBc positive rate showed higher degrees in the following order; preschool age (1-6 years), school age (6-13 years) and infancy (0-1 year). Anti-HBs positive rate was increased as the frequency of vaccination increased. Five years after initial complete vaccination, minimum protective rate was lowest, 69.6%.

• Analytical Science and Technology
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• v.32 no.6
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• pp.262-270
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• 2019

The stable isotopic composition of bone collagen plays an important role in reconstructing palaeodiet, nutrition, palaeoenvironment and their lifestyle. This is the first case in extracting palaeodietary information and breastfeeding pattern of Goryeo people using stable isotope analysis due to the lack of human remains in this period. We analyzed human bone collagen excavated from Gyeongju Donggung palace and Wolji pond No.3. The average values of δ¹³C and δ¹⁵N are as follows: (δ¹³C(‰) = -19.5 ± 0.9‰, δ¹⁵N(‰) = 11.1 ± 1.1 ‰, (n = 4). Stable carbon isotope values shows a mainly C₃ based diet such as rice and barley. Stable nitrogen isotope results implies the protein sources attributed to terrestrial animals. There are various age groups in this study, which are adult, child and infant. Two individuals within early childhood age ranges (< 3 years) shows more elevated δ¹⁵N values than that of adult and this result implies the continuation of breastfeeding in this group until the age of 3. The results provide new insight into the breastfeeding pattern of Goryeo people, where breastfeeding and weaning practices have important implication for fertility, population dynamics, migration pattern and disease.

• Journal of Life Science
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• v.10 no.3
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• pp.262-272
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• 2000

As a part of investigation for basic epidemiology of diarrheogenic disease, we attempted isolation of Escherichia coli from patients with diarrhea. Seven hundred and twenty-one strains of E. coli were isolated from 1,239 patients with diarrhea. Seasonal distribution of patient with diarrhea was shown the most high at August (18.2%). Age group distribution of patient was shown the most high at children (54.6%, 2 to 10 years old). The serotypes of 721 E. coli isolates were in order of serotype O44 (16.8%), O153 (8.6%), O1 (7.5%), O166(5.7%), O8 and O86a (4.7%), and O125 (4.6%). The supernates cultured 36 strains among 721 E. coli isolates were indicated cytotoxicity against monolayered Vero cells. All of the isolates were susceptible to amikacin. The isolates were resistant in order of novobiocin (99.0%), moxalactam (97.1%), carbenicillin (96.1%), tetracycline (90.4%), ampicillin (85.9%), gentamicin (84.0%), streptomycin (78.4%), cephalothin (46.6%) and polymyxin B (4.2%). In the antibiotic resistant patterns, 125 kinds of multiple resistance patterns of E. coli isolates were detected. The highest resistant pattern was ampicillin-carbenicillin-chloramphenicol-cephalothin-erythro-mycin- gentamicin-moxalactam-novobiocin-penicillin G-streptomycin-tobramycin-tetracycline-tri methoprim type (24.3%).

• Journal of Digital Convergence
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• v.17 no.5
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• pp.369-377
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• 2019

The purpose of this study was to investigate the effects of father's value of children and cultural orientation on the father's parenting involvement. Data were collected from 286 fathers on FPI, VOC, and COR, which then were analyzed using correlation and multiple regression. The major findings of this study were as follows: First, emotional value of children was positively related to the father's parenting involvement, but instrumental value of children was negatively related to the father's parenting involvement. Second, collectivism had a stronger relationships with the father's parenting involvement than individualism. Third, father's education level was positively related to the father's parenting involvement. The above findings imply that father's value of children is an important variables of parenting involvement and cultural orientation is also a good predictor of parenting involvement.

• Journal of Food Hygiene and Safety
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• v.25 no.2
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• pp.148-152
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• 2010

Domestic studies for identification of causality between children exposure to toxic chemicals, such as arsenic (As) and resulted hazardous effects were not implemented. This study was conducted to probabilistically estimate dietary As intake and health risk assessment for young children and all age-specific populations from the consumption of As-contaminated rice of Korea. Arsenic intakes for young children (1 to 6 years old) from As-contaminated rice were higher than other age-specific groups, based on a dose-per-body weight basis. Based on the current EPA cancer slope factor for As, estimated cancer risks (to the skin cancer) associated with dietary intake of As-contaminated rice for 1 to 2 years old group and 3 to years old group are 1.76 per 10,000 and 3.16 per 10,000, respectively, at the 50th percentile. Based on possible reference levels (0.005 mg/kg/day) for children, mean and $95^{th}$ percentile value of HQ from rice for young children are very below 1.0, which is a regulatory limit of non-carcinogenic risks for human.

• Proceedings of The KACE
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• 2017.08a
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• pp.3-5
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• 2017

본 연구의 목적은 컴퓨팅 사고력과 관련된 연구들을 연구주제, 연구대상, 적용교과를 기준으로 하여 분석함으로써 앞으로 컴퓨팅 사고력과 관련된 연구의 방향을 제시하는데 있다. 이를 위해 컴퓨팅 사고력 관련 연구 중에서 KCI 등재지 총 38편을 선정하였다. 연구주제별로 분석한 결과, CT 교육의 실천방안을 모색하는 연구들이 주를 이루었으며 이에 반해 CT 평가를 위한 도구 개발과 관련된 연구는 미미하였다. 연구대상별로 분석한 결과, 초등학생을 대상으로 한 연구가 가장 높은 비율을 차지했으며, 그 중에서도 초등학교 5학년 이상을 대상으로 한 연구가 많았다. 적용교과별로 분석한 결과, 정보교과가 가장 높게 나타났는데, 이는 초등학교의 정보교육이 정규교육과정보다 교과 외의 방법으로 진행되고 있기 때문이었다. 세 가지 결과를 바탕으로 CT 평가와 관련된 연구, 초등학교 저학년과 유아를 대상으로 한 연구가 더욱 활발하게 이루어져야하며 초등학교 전 학년을 위한 필수교과로서의 정보교육에 관한 논의가 필요하다고 결론지었다. 이를 위해 초등학생을 위한 정규교육과정 외의 정보교육의 현황을 조사 및 검토할 필요가 있음을 제언하였다.

• Child Health Nursing Research
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• v.13 no.3
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• pp.329-337
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• 2007

Purpose: This study was done to describe the essential structure of the lived experience of working women raising children. Method: Data were collected from 10 employed women with children who were under 2 years of age. The analysis of the data was done using the phenomenological analytic method suggested by Colaizzi (1978). Results: In this study, 6 essential themes were extracted: 'knowing by intuition child-rearing is difficult', 'having guilt-conscious of not being able to perform duties as a mother', 'hard work of maintaining two jobs', 'Lost self', 'realizing that one has become amother', 'thirsting for a social support system'. Conclusion: With a rapidly increasing number of working women, the significance of this study in the field of nursing is in understanding the child-rearing experience of working women. The findings indicate the need for a systemic and emotional support system for working women raising children.

• The Korean Journal of Community Living Science
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• v.19 no.3
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• pp.399-410
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• 2008

The main purpose of this study was to examine the effects of drama activities using children's literature on the improvement of young children's creativity. To answer this research question, 2 groups, an experimental group composed of 18 five-year-old children who attend "J public Kindergarten," and a control group composed of 18 five-year-old children who attend "H public Kindergarten," were organized. Both kindergartens were located in Hwaseong, Gyeonggi-do. The experimental group participated in drama activities twice a week; 16 times for 8 weeks. In this study, the change in children's creativity was measured by conducting a pre-test and a post-test developed by Chun(2000). The results after 8 weeks of experimentation indicate that the drama activities using children's literature had a positive effect on promoting children's creativity. Comparing the scores of the pre-test and the post-test, it was obvious that the experimental group's creativity had been improved. The experimental group's creativity including the sub-elements of the test such as fluency, flexibility, uniqueness, and imagination, was improved more than that of the controlled group.