• 제목/요약/키워드: 2SRI

검색결과 346건 처리시간 0.025초

Influence of Foreign Culture and Hybrid Culture: The Case of Kandyan Kingdom of Sri Lanka

  • Ranathunga, Gayathri Madubhani
    • International Journal of Costume and Fashion
    • /
    • 제13권2호
    • /
    • pp.53-64
    • /
    • 2013
  • Culture has played a pivotal role in fashion from time immemorial. The objective of this research is to explore the power of cultural affiliation in fashion. The selected study setting is the Kandyan Kingdom of Sri Lanka. The Kandyan Kingdom of Sri Lanka lasted almost 3 1/2 centuries from 1474-1815. The whole period faced different foreign cultural forces. As a result of such diverse cultural influences the Kandyan dress showed a hybrid formation of Western and South Indian and Sinhalese traditional sartorial features. Sewing techniques and unsewn dress arrangement methods were mixed together. The dress became an amazing blend of Eastern and Western dress items. They combined different aspects of foreign dress together to yield a unique result. The analysis comprises observational study of actual descriptions made by observer- participants, historical records, murals of the period review of ancient literature and research papers relevant to the subject. Reliability of the data was ensured. The pictorial data were cross checked from different literary sources. Many original sources were used. Results: Culture and fashion have strong interconnection. When features of culture change, trends of fashion are gradually correspondingly changed.

FTIR spectroscopy of the two-photon product of sensory rhodopsin I

  • Sasaki, Jun;Kannaka, Masato;Kandori, Hideki;Tokunaga, Fumio
    • Journal of Photoscience
    • /
    • 제9권2호
    • /
    • pp.534-536
    • /
    • 2002
  • A halophilic archaeon, Halobacterium salinarum, exhibits phototactic behaviors, by which the organism is guided to red-orange light and evades shorter wavelengths of light. The phototaxis is mediated by two retinal proteins, sensory rhodopsin I and II (SRI and SRII), whose structures are analogous to the cognate protein bacteriorhodopsin, a light-driven proton pump. SRI mediates both attractant and repellent swimming behaviors to orange light and near- UV light, respectively. The two different signaling through the single photoreceptor have been ascribed to the presence of two active structures of SRI (S$\_$373/ and P$\_$520), which are produced upon orange light illumination of SRI and upon subsequent near-UV illumination of S$\_$373/, respectively. In the present study, we have measured the difference FTIR spectra of S$\_$373/ and P$\_$520/ states. In P$\_$520/, the isomeric structure of the chromophore is assignable to all-trans, and the Schiff base of the chromophore is protonated with concomitant deprotonation of Asp76, a combination which allows for the formation of a salt bridge between them. It was suggested that the way of interaction between the Schiff base and the counterion, which is different among SRI$\_$587/, S$\_$373/ and P$\_$520/ and which has been shown to drive the conformational changes in the cognate protein, bacteriorhodopsin, is the key to controlling conformational changes for the attractant and the repellent signaling by SRI.

  • PDF

Endoscopic Retrograde Cholangiopancreatography in Children: Feasibility, Success, and Safety with Standard Adult Endoscopes and Accessories

  • Perera, Kasadoruge Dinesh Rangika;Nawarathne, Nawarathne Mudiyanselage Metthananda;Samarawickrama, Vajira Tharanga;Deraniyagala, Malinda Peiris;Luxman, Wickramadurayala Gedara Eranda;Fernandopulle, Anthony Nilesh Ranjeev
    • Pediatric Gastroenterology, Hepatology & Nutrition
    • /
    • 제25권5호
    • /
    • pp.406-412
    • /
    • 2022
  • Purpose: The role of endoscopic retrograde cholangiopancreatography (ERCP) in the management of hepatobiliary and pancreatic diseases in the pediatric population was not well defined until recently. Our aim was to determine the feasibility, outcomes, and safety of ERCP in a local pediatric population, particularly using standard adult endoscopes and accessories. Methods: This retrospective study was conducted at the National Hospital of Sri Lanka. Pediatric patients (aged <16 years) who underwent ERCP from January 2015 to December 2020 were included in the study. Data, including patient demographics, indications for the procedure, technical details, and associated complications, were collected from the internal database and patient records maintained at the hospital. Results: The study included 62 patients who underwent a total of 98 ERCP procedures. All the procedures were performed by adult gastroenterologists using standard adult endoscopes and accessories. The mean age was 11.01±3.47 years. Pancreatic diseases were the major indications for most of the procedures (n=81, 82.7%), with chronic pancreatitis being the most common. Seventeen procedures (17.3%) were carried out for biliary diseases. Overall cannulation and technical success rates were 87.8% and 85.7%, respectively. Stent placement was the most common therapeutic intervention (n=66; 67.4%). Post-ERCP pancreatitis was the most common complication, occurring in eight patients (8.2%). Conclusion: ERCP can be successfully and safely performed in pediatric populations using standard adult endoscopes and accessories with complications similar to those of adults. Adult ERCP services can be offered to most pediatric patients without additional costs of pediatric endoscopes and accessories.

ESP 기법을 이용한 수문학적 가뭄전망의 활용성 평가 (Applicability Assessment of Hydrological Drought Outlook Using ESP Method)

  • 손경환;배덕효
    • 한국수자원학회논문집
    • /
    • 제48권7호
    • /
    • pp.581-593
    • /
    • 2015
  • 본 연구에서는 ESP (Ensemble Streamflow Prediction)기법을 활용한 가뭄전망 체계를 구축하고 가뭄예보에 있어 활용성을 평가하였다. 과거 관측 수문기상 및 지형정보를 이용하여 우리나라 전역에 지면모델(Land Surface Model, LSM)을 구축하고 유출량(Historical Runoff, HR)을 생산하였다. 또한, 모의기간 동안 과거 30개 기상자료와 초기 토양수분량을 이용하여 선행시간별(1, 2, 3개월) 전망된 유출량(Predicted Runoff, PR)을 생산하였다. 평가결과 여름 및 가을철 보다 봄철 및 겨울철에 정확도가 높았으며, 1개월 전망 이후로는 정확도가 낮게 나타났다. 가뭄지수는 국내 가뭄해석에 있어 검증된 표준유출지수(Standardized Runoff Index, SRI)를 활용하였으며, PR_SRI을 산정 및 평가하였다. 1, 2개월 전망에서는 과거 HR이 고려되어 ESP HR에 비해 정확도가 크게 개선됨을 알 수 있었다. 선행시간별 상관계수는 평균 0.71, 0.48, 0.00, 평균제곱근오차는 0.46, 0.76, 1.01로 나타났으며, 건조기에 정확도가 높게 나타나 1, 2개월 전망까지는 ESP를 활용한 국내 가뭄예보의 활용성이 높다고 판단된다.

TiO2 Nanoparticles from Baker's Yeast: A Potent Antimicrobial

  • Peiris, MMK;Guansekera, TDCP;Jayaweera, PM;Fernando, SSN
    • Journal of Microbiology and Biotechnology
    • /
    • 제28권10호
    • /
    • pp.1664-1670
    • /
    • 2018
  • Titanium dioxide ($TiO_2$) has wide applications in food, cosmetics, pharmaceuticals and manufacturing due to its many properties such as photocatalytic activity and stability. In this study, the biosynthesis of $TiO_2$ nanoparticles (NPs) was achieved by using Baker's yeast. $TiO_2$ NPs were characterized by X-ray Diffraction (XRD), UV-Visible spectroscopy, Scanning Electron Microscopy (SEM), Transmission Electron Microscopy (TEM) and Energy Dispersive X-ray analysis (EDX) studies. The XRD pattern confirmed the formation of pure anatase $TiO_2$ NPs. According to EDX data Ti, O, P and N were the key elements present in the sample. SEM and TEM revealed that the nanoparticles produced were spherical in shape with an average size of $6.7{\pm}2.2nm$. The photocatalytic activity of $TiO_2$ NPs was studied by monitoring the degradation of methylene blue dye when treated with $TiO_2$ NPs. $TiO_2$ NPs were found to be highly photocatalytic comparable to commercially available 21 nm $TiO_2$ NPs. This study is the first report on antimicrobial study of yeast-mediated $TiO_2$ NPs synthesized using $TiCl_3$. Antimicrobial activity of $TiO_2$ NPs was greater against selected Gram-positive bacteria and Candida albicans when compared to Gram-negative bacteria both in the presence or absence of sunlight exposure. $TiO_2$ NPs expressed a significant effect on microbial growth. The results indicate the significant physical properties and the impact of yeast-mediated $TiO_2$ N Ps as a novel antimicrobial.

ORTHOGONAL GENERALIZED SYMMETRIC REVERSE BIDERIVATIONS IN SEMI PRIME RINGS

  • V.S.V. KRISHNA MURTY;C. JAYA SUBBA REDDY
    • Journal of Applied and Pure Mathematics
    • /
    • 제6권3_4호
    • /
    • pp.155-165
    • /
    • 2024
  • Let R be a semi-prime ring. Let [δ1, D1] and [δ2, D2] be two generalized symmetric reverse biderivations of R with associated reverse biderivations D1 and D2. The main aim of the present paper is to establish conditions of orthogonality for symmetric reverse biderivations and symmetric generalized reverse biderivations in R.

Characterization of Alpha Amylase Producing Thielaviopsis ethacetica and Its Raw Starch Hydrolyzing Ability on Different Agricultural Substrates

  • Dissanayaka, Dissanayaka M.S.;De Silva, Sembukuttige N.T.;Attanayaka, D.P.S.T.G.;Kurera, Mihidukulasuriya J.M.S.;Fernando, Charakrawarthige A.N.
    • 한국미생물·생명공학회지
    • /
    • 제47권3호
    • /
    • pp.412-422
    • /
    • 2019
  • The present study reports the morphological and molecular characterization of the fungal strain, CMSS06 and evaluates its raw starch hydrolyzing ability in four different agricultural substrates (rice bran, banana peel, cassava tubers, and coconut water). The potential use of each agricultural substrate to replace the expensive fermentation media was evaluated with six different fermentation media: rice bran (RB), banana peel (BP), cassava starch (CS), cassava in coconut water (CSCW), cassava in modified coconut water (CMCW), and pure Coconut water (CW). The fungal strain CMSS06 was identified as Thielaviopsis ethacetica by the analysis of the ITS sequences. The T. ethacetica alpha amylase enzyme exhibited maximum alpha amylase activity at 72 h, pH 7.0, and $40^{\circ}C$ on soluble starch. This species resulted in the highest enzyme activity (mU/ml) of 26.06, 10.89, 58.82, 14.2, and 54.67 with the RB, BP, CS, CSCW, and CMCW fermentation media, respectively. The results indicate that CS can be used as a carbon substrate and CMCW can be used to accelerate the fermentation by T. ethacetica. The enzyme was partially purified by 40-60% ammonium sulphate fraction, and it showed total enzyme activity, total protein content, specific activity, purification fold, and a recovery of 2400 mU, 30 mg, 80 mU/mg, 2.7, and 71.1%, respectively. The molecular mass of the T. ethacetica alpha amylase was estimated on SDS-PAGE, and two bands around 50 kDa and 70 kDa were identified. The present study implies that T. ethacetica can produce alpha amylase, and it can be used to hydrolyze raw starch during the fermentation processes.

Detection of immunity in sheep following anti-rabies vaccination

  • Hasanthi Rathnadiwakara;Mangala Gunatilake;Florence Cliquet;Marine Wasniewski;Mayuri Thammitiyagodage;Ramani Karunakaran;Jean-Christophe Thibault;Mohamed Ijas
    • Clinical and Experimental Vaccine Research
    • /
    • 제12권2호
    • /
    • pp.97-106
    • /
    • 2023
  • Purpose: Rabies is a fatal but preventable disease with proper pre-exposure anti-rabies vaccination (ARV). Dogs, as household pets and strays, are the reservoir and vector of the disease, and dog bites have been associated with human rabies cases in Sri Lanka over the past few years. However, other susceptible species having frequent contact with humans may be a source of infection. One such species is sheep and immunity following ARV has never been tested in sheep reared in Sri Lanka. Materials and Methods: We have tested serum samples from sheep reared in the Animal Centre, Medical Research Institute of Sri Lanka for the presence of anti-rabies antibodies following ARV. Sheep serum samples were tested with Bio-Pro Rabies enzyme-linked immunosorbent assay (ELISA) antibody kits used for the first time in Sri Lanka and our results were verified by a seroneutralization method on cells (fluorescent antibody virus neutralization, FAVN test) currently recommended by World Organization for Animal Health and World Health Organization. Results: Sheep received annual ARV and maintained high neutralizing antibody titers in their serum. No maternal antibodies were detected in lamb around 6 months of age. Agreement between the ELISA and FAVN test, i.e., coefficient concordance was 83.87%. Conclusion: Annual vaccination in sheep has an effect on maintaining adequate protection against rabies by measurements of anti-rabies antibody response. Lambs need to be vaccinated earlier than 6 months of age to achieve protective levels of neutralizing antibodies in their serum. Introducing this ELISA in Sri Lanka will be a good opportunity to determine the level of anti-rabies antibodies in animal serum samples.

TP53 Polymorphisms in Sporadic North Indian Breast Cancer Patients

  • Sharma, Sarika;Sambyal, Vasudha;Guleria, Kamlesh;Manjari, Mridu;Sudan, Meena;Uppal, Manjit Singh;Singh, Neeti Rajan;Bansal, Darpan;Gupta, Arun
    • Asian Pacific Journal of Cancer Prevention
    • /
    • 제15권16호
    • /
    • pp.6871-6879
    • /
    • 2014
  • Background: The purpose of this study was to evaluate the potential association of five (p.P47S, p.R72P, PIN3 Ins16bp, p.R213R and r.13494g>a) polymorphisms of TP53 with the risk of developing breast cancer in North Indian Punjabi population. Methods: We screened DNA samples of 200 sporadic breast cancer patients (197 females and 3 males) and 200 unrelated healthy, gender and age matched individuals for the polymorphisms. Results: For the p.P47S polymorphism, we observed the PP genotype in 99.5% of the patients and PS genotype in only 1 patient. All the controls had the wild type PP genotype. The frequency of RR, RP and PP genotype of p.R72P was 23.5% vs 33.5%, 51.5% vs 45.5% and 25% vs 21% in patients and controls respectively. Heterozygous (RP) genotype was increased in breast cancer patients as compared to controls (51.5 vs 45.5%) and showed 1.61 fold significantly increased risk for breast cancer (OR=1.61, 95% CI, 1.01-2.58, p=0.04). In breast cancer patients the frequencies of A1A1, A1A2 and A2A2 genotypes of PIN3 Ins16bp polymorphism were 67%, 26% and 7% respectively whereas in controls the genotype frequencies were 68.5%, 27.5% and 4% respectively, with no significant difference. For p.R213R (c.639A>G), all individuals had homozygous wild type genotype. The frequencies of GG, GA and AA genotypes of TP53 r.13494g>a polymorphism were 62 vs 67.5%, 33 vs 28% and 5 vs 4.5% in patients and controls respectively, again without significant difference. We observed that RP-A1A1 genotype combination of p.R72P and PIN3 Ins16bp and RP-GG combination of p.R72P and r.13494g>a polymorphism showed significant risk of breast cancer (OR=1.65, 95%CI: 0.98-2.78, p=0.05; OR=1.72, 95%CI: 1.01-2.92, p=0.04). Conclusion: The results of present study indicated that among the five TP53 polymorphisms investigated, the p.R72P polymorphism, and the RP-A1A1 and RP-GG genotype combination contribute to breast cancer susceptibility in North Indians.

수문학적 가뭄전망을 위한 GloSea5의 활용체계 구축 및 예측성 평가 (Construction & Evaluation of GloSea5-Based Hydrological Drought Outlook System)

  • 손경환;배덕효;정현숙
    • 대기
    • /
    • 제25권2호
    • /
    • pp.271-281
    • /
    • 2015
  • The objectives of this study are to develop a hydrological drought outlook system using GloSea5 (Global Seasonal forecasting system 5) which has recently been used by KMA (Korea Meteorological Association) and to evaluate the forecasting capability. For drought analysis, the bilinear interpolation method was applied to spatially downscale the low-resolution outputs of GloSea5 and PR (Predicted Runoff) was produced for different lead times (i.e., 1-, 2-, 3-month) running LSM (Land Surface Model). The behavior of PR anomaly was similar to that of HR (Historical Runoff) and the estimated values were negative up to lead times of 1- and 2-month. For the evaluation of drought outlook, SRI (Standardized Runoff Index) was selected and PR_SRI estimated using PR. ROC score was 0.83, 0.71, 0.60 for 1-, 2- and 3-month lead times, respectively. It also showed the hit rate is high and false alarm rate is low as shorter lead time. The temporal Correlation Coefficient (CC) was 0.82, 0.60, 0.31 and Root Mean Square Error (RMSE) was 0.52, 0.86, 1.20 for 1-, 2-, 3-month lead time, respectively. The accuracy of PR_SRI was high up to 1- and 2-month lead time on local regions except the Gyeonggi and Gangwon province. It can be concluded that GloSea5 has high applicability for hydrological drought outlook.