• Title/Summary/Keyword: 2D field solution

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3D-QSAR Analysis on Antidepressant Activity of Tricyclic Isoxazole Analogues against Medetomidine-induced Loss of Righting (Medetomidine에 유발된 정좌반사소실에 대한 Tricyclic Isoxazole 유도체들의 항우울성에 관한 3D-QSAR 분석)

  • Choi, Min-Sung;Sung, Nack-Do;Myung, Pyung-Keun
    • YAKHAK HOEJI
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    • v.55 no.2
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    • pp.98-105
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    • 2011
  • To search the minimum structural requirement of tricyclic isoxazole analogues (1~30) as new class potent antidepressant, thee-dimensional quanti- tative-structure relationship (3D-QSAR) models between substituents ($R_1{\sim}R_5$) of tricyclic isoxazoles and their antidepressant activity against medetomidine-induced loss of righting were performed and discussed quantitatively using comparative molecular field analysis (CoMFA) and comparative molecular similarity indies analysis (CoMSIA) methods. The correlativity and predictability ($r^2$=0.484 and $q^2$=0.947) of CoMSIA-2 model were higher than those of the rest models. The inhibitory activity against medetomidine-induced loss of righting was dependent on electrostatic field (43.4%), hydrophobic field (35.3%), and steric field (21.2%) of tricyclic isoxazoles. From the CoMSIA-2 contour maps, it is predicted that the antidepressant activity of potent antidepressants against medetomidine-induced loss of righting will be able to increase by the substituents ($R_1{\sim}R_5$) which were in accord with CoMSIA field.

Seismic Response Analysis Considering the Site Effect in Two Dimensional Cases (부지효과를 고려한 2차원 평면상의 지진응답해석)

  • 김민규;임윤묵;김문겸
    • Proceedings of the Earthquake Engineering Society of Korea Conference
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    • 2001.09a
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    • pp.83-90
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    • 2001
  • The site effects of local geological conditions on seismic ground motion are performed using 2D numerical method. For the analysis, a numerical method far ground response analysis using FE-BE coupling method is developed. The total system is divided into two parts so called far field and near field. The far field is modeled by boundary element formulation using the multi-layered dynamic fundamental solution that satisfied radiational condition of wave. And this is coupled with near field modeled by finite elements. In order to verify the seismic response analysis, the results are compared with those of commercial code. As a result, it is shown that the developed method can be an efficient numerical method to solve the seismic response analysis of the site effect in 2D problem.

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3D-QSAR Analysis of Antidepressant, Tricyclic Isoxazole Analogues against para-Chloroamphetamine-induced Excitation (para-Chloroamphetamine에 유도된 흥분작용에 대한 항우울 약물 Tricyclic Isoxazole 유도체들의 3D-QSAR 분석)

  • Choi, Min-Sung;Sung, Nack-Do;Myung, Pyung-Keun
    • YAKHAK HOEJI
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    • v.55 no.2
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    • pp.91-97
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    • 2011
  • To search a new anti-depressant agents against para-chloroamphetamine-induced excitation, three dimensional quantitative-structure relationships (3D-QSAR) models between structure of 3a,4-dihydro-3H-[1]-benzopyronao[4,3]isoxazoles (1-30) and thieir inhibitory activity against para-chloroamphetamine-induced excitation were performed and discussed quantitatively using comparative molecular field analysis (CoMFA) and comparative molecular similarity indices analysis (CoMSIA) methods. From these basis on the findings, the optimized CoMSIA-2F model ($q^2$=0.793 and $r^2$=0.952) showed the best statistical results. And also, it is found that the para-chloroamphetamine inhibitory activity from the optimized CoMSIA-2F model was dependent on steric field (35.2%) and electrostatic field (64.8%) of tricyclic isoxazoles. Particularly, it is predicted that the inhibitory activity against para-chloroamphetamine-induced excitation will be able to increase by the designed compounds from the CoMSIA-2F model.

How to Impose the Boundary Conditions Operatively in Force-Free Field Solvers

  • Choe, Gwang Son;Yi, Sibaek;Jun, Hongdal
    • The Bulletin of The Korean Astronomical Society
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    • v.44 no.2
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    • pp.69.2-69.2
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    • 2019
  • To construct a coronal force-free magnetic field, we must impose the boundary normal current density (or three components of magnetic field) as well as the boundary normal field at the photosphere as boundary conditions. The only method that is known to implement these boundary conditions exactly is the method devised by Grad and Rubin (1958). However, the Grad-Rubin method and all its variations (including the fluxon method) suffer from convergence problems. The magnetofrictional method and its variations are more robust than the Grad-Rubin method in that they at least produce a certain solution irrespective of whether the global solution is compatible with the imposed boundary conditions. More than often, the influence of the boundary conditions does not reach beyond one or two grid planes next to the boundary. We have found that the 2D solenoidal gauge condition for vector potentials allows us to implement the required boundary conditions easily and effectively. The 2D solenoidal condition is translated into one scalar function. Thus, we need two scalar functions to describe the magnetic field. This description is quite similar to the Chandrasekhar-Kendall representation, but there is a significant difference between them. In the latter, the toroidal field has both Laplacian and divergence terms while in ours, it has only a 2D Laplacian term. The toroidal current density is also expressed by a 2D Laplacian. Thus, the implementation of boundary normal field and current are straightforward and their effect can permeate through the whole computational domain. In this paper, we will give detailed math involved in this formulation and discuss possible lateral and top boundary conditions and their meanings.

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Recovery of 3-D Motion from Time-Varying Image Flows

  • Wohn, Kwang-Yun;Jung, Soon-Ki
    • Journal of Electrical Engineering and information Science
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    • v.1 no.2
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    • pp.77-86
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    • 1996
  • In this paper we deal with the problem of recovering 3-D motion and structure from a time-varying 2-D velocity vector field. A great deal has been done on this topic, most of which has concentrated on finding necessary and sufficient conditions for there to be a unique 3-D solution corresponding to a given 2-D motion. While previous work provides useful theoretical insight, in most situations the known algorithms have turned out to be too sensitive to be of much practical use. It appears that any robust algorithm must improve the 3-D solutions over time. As a step toward such algorithm, we present a method for recovering 3-D motion and structure from a given time-varying 2-D velocity vector field. The surface of the object in the scene is assumed to be locally planar. It is also assumed that 3-D velocity vectors are piecewise constant over three consecutive frames (or two snapshots of flow field). Our formulation relates 3-D motion and object geometry with the optical flow vector as well as its spatial and temporal derivatives. The linearization parameters, or equivalently, the first-order flow approximation (in space and time) is sufficient to recover rigid body motion and local surface structure from the local instantaneous flow field. We also demonstrate, through a sensitivity analysis carried out for synthetic and natural motions in space, that 3-D motion can be recovered reliably.

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Deep UV 마이크로 리소그라피를 위한 새로운 4-반사경 광학계에 관한 수차해석

  • 김종태;이상수
    • Korean Journal of Optics and Photonics
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    • v.4 no.1
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    • pp.1-8
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    • 1993
  • A design of four-mirror optical system with reduction magnification 5X for deep UV ($\lambda$=248 nm of KrF excimer laser) submicron lithography is presented. Initially by using the paraxial quantities, the domain of solution for $t=d_1+d_2+d_3$<0 (d;: distance between the mirror $c_i$ and $c_{i+1}$ is found for the system which is free from the four off-axial Seidel first order aberrations that are coma, astigmatism, field curvature, and distortion. The solution with $d_5$=2.95 (normalized with respect to $c_i$= -1) is choosen and the aspherization is carried out to the spherical mirror surfaces ($c_3$ and $c_4$ in order to reduce the axial and residual off-axial higher order aberrations. The numerical aperture of the final system is as large as 0.4, which gives Rayleigh resolution of 0.38 $\mu\textrm{m}$.

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EFFICINET GENERATION OF MAXIMAL IDEALS IN POLYNOMIAL RINGS

  • Kim, Sunah
    • Bulletin of the Korean Mathematical Society
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    • v.29 no.1
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    • pp.137-143
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    • 1992
  • The purpose of this paper is to provide the affirmative solution of the following conjecture due to Davis and Geramita. Conjecture; Let A=R[T] be a polynomial ring in one variable, where R is a regular local ring of dimension d. Then maximal ideals in A are complete intersection. Geramita has proved that the conjecture is true when R is a regular local ring of dimension 2. Whatwadekar has rpoved that conjecture is true when R is a formal power series ring over a field and also when R is a localization of an affine algebra over an infinite perfect field. Nashier also proved that conjecture is true when R is a local ring of D[ $X_{1}$,.., $X_{d-1}$] at the maximal ideal (.pi., $X_{1}$,.., $X_{d-1}$) where (D,(.pi.)) is a discrete valuation ring with infinite residue field. The methods to establish our results are following from Nashier's method. We divide this paper into three sections. In section 1 we state Theorems without proofs which are used in section 2 and 3. In section 2 we prove some lemmas and propositions which are used in proving our results. In section 3 we prove our main theorem.eorem.rem.

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Development and Effects of Virtual Geological Field Trip Program using 360° 3D Panorama Technique (360° 3D 파노라마 기술을 적용한 VFT 개발 및 효과)

  • Kim, Hee Soo
    • Journal of the Korean Society of Earth Science Education
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    • v.8 no.2
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    • pp.193-205
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    • 2015
  • In this study, a Virtual geological Field Trip(VFT) learning program using 3D panorama virtual reality techniques was developed to learn about the Gongju city 7 area located in Chungcheongnam-do, Korea. The developed $360^{\circ}$ 3D VFT program can show every face of observational points and interact as zoom-in, zoom-out and image rotation. For the educational effects of the materials, it is provided with a compass, a protractor, enlarged images, pop-up windows, etc.. The program was applied to the class of 35 gifted students in middle school to investigate the effectiveness of the program. The results showed that positive responses of the students were 90% or more. When geological field trip problems like cost, safety, distance occur in geological learning procedure of middle school science, this VFT program can become as a supplementary learning material and a solution.

NMR Chemical Shift for 4d$^n$ System (Ⅱ). Calculation of the Pseudo Contact Shift for a 4d$^1$ System in a Strong Crystal Field Environment of Octahedral Symmetry

  • Sang-woon Ahn;Se-Woong Oh;Eui-suh Park
    • Bulletin of the Korean Chemical Society
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    • v.4 no.2
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    • pp.64-67
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    • 1983
  • NMR shift arising from the electron orbital angular momentum and the electron spin dipolar-nuclear spin angular momentum interactions has been investigated for a $4d^{1}$ system in a strong crystal field of octahedral symmetry. To examine the NMR shif for a $4d^{1}$ system in a strong crystal field of octahedral symmetry, we derive a general expression for ${\Delta}$B/B using a nonmultipole expansion technique. From this expression all the multipolar terms are determined. For the $4d^{1}$ system in a strong crystal field of octahedral symmetry the exact solution for NMR shift, ${\Delta}$B, is compared with the multipolar results. ${\Delta}$B/B for the $4d^{1}$ system is also compared with that for the $3d^{1}$ system. It is found that the $1/R^{7}$ term contributes dominantly to the NMR shift. However, there is good agreement between the nonmultipole and multipolar results for R-values larger than 0.2 nm for the $4d^{1}$ system but for R-values larger than 0.4 nm for the $3d^{1}$ system.

CNT Emitter Coated with Titanium Oxide Nanoparticles for FED Application

  • Kim, Jong-Ung;Ryu, Byong-Hwan;Moon, Hee-Sung;Kim, Jae-Myeong;No, Cho-Hang;Uk, Park-Seoung;Choi, Young-Min
    • 한국정보디스플레이학회:학술대회논문집
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    • 2007.08a
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    • pp.937-939
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    • 2007
  • Carbon nanotubes (CNTs) have used as an electron field emitter of the field emission display (FED) due to their characteristics of high-electron emission, rapid response and low power consumption. However, to commercialize the FED with CNT emitter, some fundamental problems regarding life time and emission efficiency have to be solved. In this study, we investigated the $TiO_2$ coated CNT as a field emitter. $TiO_2$ nanoparticles can coated on CNT surface by chemical solution method. $TiO_2$ nanoparticles had uniform size with the average size of about 2.4 nm to 3.1 nm. Field emission performance of CNT coated with $TiO_2$ nanoparticles was evaluated and discussed.

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