• 약학회지
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• 제55권2호
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• pp.98-105
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• 2011

To search the minimum structural requirement of tricyclic isoxazole analogues (1~30) as new class potent antidepressant, thee-dimensional quanti- tative-structure relationship (3D-QSAR) models between substituents ($R_1{\sim}R_5$) of tricyclic isoxazoles and their antidepressant activity against medetomidine-induced loss of righting were performed and discussed quantitatively using comparative molecular field analysis (CoMFA) and comparative molecular similarity indies analysis (CoMSIA) methods. The correlativity and predictability ($r^2$=0.484 and $q^2$=0.947) of CoMSIA-2 model were higher than those of the rest models. The inhibitory activity against medetomidine-induced loss of righting was dependent on electrostatic field (43.4%), hydrophobic field (35.3%), and steric field (21.2%) of tricyclic isoxazoles. From the CoMSIA-2 contour maps, it is predicted that the antidepressant activity of potent antidepressants against medetomidine-induced loss of righting will be able to increase by the substituents ($R_1{\sim}R_5$) which were in accord with CoMSIA field.

• 한국지진공학회:학술대회논문집
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• 한국지진공학회 2001년도 추계 학술발표회 논문집 Proceedings of EESK Conference-Fall 2001
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• pp.83-90
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• 2001

The site effects of local geological conditions on seismic ground motion are performed using 2D numerical method. For the analysis, a numerical method far ground response analysis using FE-BE coupling method is developed. The total system is divided into two parts so called far field and near field. The far field is modeled by boundary element formulation using the multi-layered dynamic fundamental solution that satisfied radiational condition of wave. And this is coupled with near field modeled by finite elements. In order to verify the seismic response analysis, the results are compared with those of commercial code. As a result, it is shown that the developed method can be an efficient numerical method to solve the seismic response analysis of the site effect in 2D problem.

• 약학회지
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• 제55권2호
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• pp.91-97
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• 2011

To search a new anti-depressant agents against para-chloroamphetamine-induced excitation, three dimensional quantitative-structure relationships (3D-QSAR) models between structure of 3a,4-dihydro-3H-[1]-benzopyronao[4,3]isoxazoles (1-30) and thieir inhibitory activity against para-chloroamphetamine-induced excitation were performed and discussed quantitatively using comparative molecular field analysis (CoMFA) and comparative molecular similarity indices analysis (CoMSIA) methods. From these basis on the findings, the optimized CoMSIA-2F model ($q^2$=0.793 and $r^2$=0.952) showed the best statistical results. And also, it is found that the para-chloroamphetamine inhibitory activity from the optimized CoMSIA-2F model was dependent on steric field (35.2%) and electrostatic field (64.8%) of tricyclic isoxazoles. Particularly, it is predicted that the inhibitory activity against para-chloroamphetamine-induced excitation will be able to increase by the designed compounds from the CoMSIA-2F model.

• 천문학회보
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• 제44권2호
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• pp.69.2-69.2
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• 2019

To construct a coronal force-free magnetic field, we must impose the boundary normal current density (or three components of magnetic field) as well as the boundary normal field at the photosphere as boundary conditions. The only method that is known to implement these boundary conditions exactly is the method devised by Grad and Rubin (1958). However, the Grad-Rubin method and all its variations (including the fluxon method) suffer from convergence problems. The magnetofrictional method and its variations are more robust than the Grad-Rubin method in that they at least produce a certain solution irrespective of whether the global solution is compatible with the imposed boundary conditions. More than often, the influence of the boundary conditions does not reach beyond one or two grid planes next to the boundary. We have found that the 2D solenoidal gauge condition for vector potentials allows us to implement the required boundary conditions easily and effectively. The 2D solenoidal condition is translated into one scalar function. Thus, we need two scalar functions to describe the magnetic field. This description is quite similar to the Chandrasekhar-Kendall representation, but there is a significant difference between them. In the latter, the toroidal field has both Laplacian and divergence terms while in ours, it has only a 2D Laplacian term. The toroidal current density is also expressed by a 2D Laplacian. Thus, the implementation of boundary normal field and current are straightforward and their effect can permeate through the whole computational domain. In this paper, we will give detailed math involved in this formulation and discuss possible lateral and top boundary conditions and their meanings.

• Journal of Electrical Engineering and information Science
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• 제1권2호
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• pp.77-86
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• 1996

In this paper we deal with the problem of recovering 3-D motion and structure from a time-varying 2-D velocity vector field. A great deal has been done on this topic, most of which has concentrated on finding necessary and sufficient conditions for there to be a unique 3-D solution corresponding to a given 2-D motion. While previous work provides useful theoretical insight, in most situations the known algorithms have turned out to be too sensitive to be of much practical use. It appears that any robust algorithm must improve the 3-D solutions over time. As a step toward such algorithm, we present a method for recovering 3-D motion and structure from a given time-varying 2-D velocity vector field. The surface of the object in the scene is assumed to be locally planar. It is also assumed that 3-D velocity vectors are piecewise constant over three consecutive frames (or two snapshots of flow field). Our formulation relates 3-D motion and object geometry with the optical flow vector as well as its spatial and temporal derivatives. The linearization parameters, or equivalently, the first-order flow approximation (in space and time) is sufficient to recover rigid body motion and local surface structure from the local instantaneous flow field. We also demonstrate, through a sensitivity analysis carried out for synthetic and natural motions in space, that 3-D motion can be recovered reliably.

• 한국광학회지
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• 제4권1호
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• pp.1-8
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• 1993

축소배율(5$\times$)을 갖고, Seidel 1차 수차중 4개의 비축수차인 코마(coma), 비점수차(astigmatism), 상면만곡(field curvature) 그리고 왜곡수차(distortion)가 제거된 마이크로 리소그라피를 위한 4-구면 반사경 광학계를 해석적으로 구하였다. 이때, $t=d_1+d_2+d_3$<0, (di는 반사거울 $c_i$와 $c_{i+1}$ 사이의 거리)이고, 축상 수차인 구면수차와 잔류고차수차는 반사거울 $c_3$와 $c_4$를 비구면화 하므로서 제거하였다. 이렇게 설계된 4-반사경 광학계의 N.A.는 0.4로서 Rayleigh분해능은 0.38 $\mu\textrm{m}$이다.

• 대한수학회보
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• 제29권1호
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• pp.137-143
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• 1992

The purpose of this paper is to provide the affirmative solution of the following conjecture due to Davis and Geramita. Conjecture; Let A=R[T] be a polynomial ring in one variable, where R is a regular local ring of dimension d. Then maximal ideals in A are complete intersection. Geramita has proved that the conjecture is true when R is a regular local ring of dimension 2. Whatwadekar has rpoved that conjecture is true when R is a formal power series ring over a field and also when R is a localization of an affine algebra over an infinite perfect field. Nashier also proved that conjecture is true when R is a local ring of D[ $X_{1}$,.., $X_{d-1}$] at the maximal ideal (.pi., $X_{1}$,.., $X_{d-1}$) where (D,(.pi.)) is a discrete valuation ring with infinite residue field. The methods to establish our results are following from Nashier's method. We divide this paper into three sections. In section 1 we state Theorems without proofs which are used in section 2 and 3. In section 2 we prove some lemmas and propositions which are used in proving our results. In section 3 we prove our main theorem.eorem.rem.

• 대한지구과학교육학회지
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• 제8권2호
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• pp.193-205
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• 2015

In this study, a Virtual geological Field Trip(VFT) learning program using 3D panorama virtual reality techniques was developed to learn about the Gongju city 7 area located in Chungcheongnam-do, Korea. The developed $360^{\circ}$ 3D VFT program can show every face of observational points and interact as zoom-in, zoom-out and image rotation. For the educational effects of the materials, it is provided with a compass, a protractor, enlarged images, pop-up windows, etc.. The program was applied to the class of 35 gifted students in middle school to investigate the effectiveness of the program. The results showed that positive responses of the students were 90% or more. When geological field trip problems like cost, safety, distance occur in geological learning procedure of middle school science, this VFT program can become as a supplementary learning material and a solution.

• Bulletin of the Korean Chemical Society
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• 제4권2호
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• pp.64-67
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• 1983

NMR shift arising from the electron orbital angular momentum and the electron spin dipolar-nuclear spin angular momentum interactions has been investigated for a $4d^{1}$ system in a strong crystal field of octahedral symmetry. To examine the NMR shif for a $4d^{1}$ system in a strong crystal field of octahedral symmetry, we derive a general expression for ${\Delta}$B/B using a nonmultipole expansion technique. From this expression all the multipolar terms are determined. For the $4d^{1}$ system in a strong crystal field of octahedral symmetry the exact solution for NMR shift, ${\Delta}$B, is compared with the multipolar results. ${\Delta}$B/B for the $4d^{1}$ system is also compared with that for the $3d^{1}$ system. It is found that the $1/R^{7}$ term contributes dominantly to the NMR shift. However, there is good agreement between the nonmultipole and multipolar results for R-values larger than 0.2 nm for the $4d^{1}$ system but for R-values larger than 0.4 nm for the $3d^{1}$ system.

• 한국정보디스플레이학회:학술대회논문집
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• 한국정보디스플레이학회 2007년도 7th International Meeting on Information Display 제7권1호
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• pp.937-939
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• 2007

Carbon nanotubes (CNTs) have used as an electron field emitter of the field emission display (FED) due to their characteristics of high-electron emission, rapid response and low power consumption. However, to commercialize the FED with CNT emitter, some fundamental problems regarding life time and emission efficiency have to be solved. In this study, we investigated the $TiO_2$ coated CNT as a field emitter. $TiO_2$ nanoparticles can coated on CNT surface by chemical solution method. $TiO_2$ nanoparticles had uniform size with the average size of about 2.4 nm to 3.1 nm. Field emission performance of CNT coated with $TiO_2$ nanoparticles was evaluated and discussed.