• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.25 no.3
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• pp.113-120
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• 2014

This is an analysis report of the "Korean Academy of Child and Adolescent Psychiatry (KACAP), Vision 2033 Survey". The survey questionnaires were developed by the planning department of KACAP and sent to KACAP members from 2012 to 2013. This survey consisted of six categories : membership, academic activity, journal publication, administrative system, fellowship training program, and future planning. The response rate was 40.5%. In addition to multiple choice questions, responders also described their own ideas and suggestions regarding KACAP. The results of this study can be used as evidence for planning the vision 2033 of KACAP.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.37A no.10
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• pp.858-864
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• 2012

In South Korea, to effective and systematic response to disasters, the government will build wireless communication network for PPDR(Public Protection and Disaster Relief) on a national level by 2015. To do it, as MOPAS(Ministry of Public Administration and Security) requested the new frequency assignment for PPDR, KCC(Korea Communications Commission) has been examined new frequency allocations about TETRA and WiBro technologies. In this paper, we were defined the technical parameters, were estimated the spectrum of TETRA-TRS requirements for Korean wireless communication of PPDR based on M.2033 methodology recommended by ITU-R.

• The Korean Journal of Physiology and Pharmacology
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• v.25 no.2
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• pp.111-118
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• 2021

27-Hydroxycholesterol (27OHChol) exhibits agonistic activity for liver X receptors (LXRs). To determine roles of the LXR agonistic activity in macrophage gene expression, we investigated the effects of LXR inhibition on the 27OHChol-induced genes. Treatment of human THP-1 cells with GSK 2033, a potent cell-active LXR antagonist, results in complete inhibition in the transcription of LXR target genes (such as LXRα and ABCA1) induced by 27OHChol or a synthetic LXR ligand TO 901317. Whereas expression of CCL2 and CCL4 remains unaffected by GSK 2033, TNF-α expression is further induced and 27OHChol-induced CCL3 and CXCL8 genes are suppressed at both the transcriptional and protein translation levels in the presence of GSK 2033. This LXR antagonist downregulates transcript levels and surface expression of CD163 and CD206 and suppresses the transcription of CD14, CD80, and CD86 genes without downregulating their surface levels. GSK 2033 alone had no effect on the basal expression levels of the aforementioned genes. Collectively, these results indicate that LXR inhibition leads to differential regulation of 27-hydroxycholesterol-induced genes in macrophages. We propose that 27OHChol induces gene expression and modulates macrophage functions via LXR-dependent and -independent mechanisms.

• Bulletin of the Korean Chemical Society
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• v.29 no.10
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• pp.2033-2035
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• 2008

• The Journal of Internal Korean Medicine
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• v.31 no.4
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• pp.752-762
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• 2010

Objective : In the present study, we investigated genetic distribution of eight single nucleotide polymorphisms of PON1 between Dampness and Phlegm and non Dampness and Phlegm pattern identification(PI) among Korean stroke patients. Materials and Methods : One hundred forty stroke subject without Dampness and Phlegm and fifty eight stroke subjects with Dampness and Phlegm were participated in this study. After informed consents, eight single nucleotide polymorphisms(SNPs) in PON1 of each subjects were identified by DNA sequencing and primer extension method and statistical analysis was performed to determine the significant difference between Dampness and Phlegm and non Dampness and Phlegm groups. Results : Among anthropometric characteristics and blood parameters, waist circumference and total cholesterol were significantly higher in Dampness and Phlegm. Among 8 SNPs of PON1, frequency of M allele and subjects with M allele in L55M SNP were significantly higher in Dampness and Phlegm group (p=0.0032 and p=0.0053, respectively) but subjects with T allele in C-2033T SNP were lower in Dampness and Phlegm group(p=0.0302). Effect of L55M and C-2033T on Dampness and Phlegm were 3.07% and 1.75%, respectively. Conclusion : Our results suggest that L55M SNP in exon and C-2033T in promoter region of PON1 maybe affect to Dampness and Phlegm pattern identification. However, further study should be carried out to find out the detailed mechanism how L55M and C-2033T can affect Dampness and Phlegm stroke patients.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.23 no.11 s.170
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• pp.2033-2039
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• 1999

One of the main causes of severe wear or crack initiation in wheel and rail is the contact stress due to wheel-rail contact. In this paper, the shape design based on more reasonable contact stress analysis rather than a general Hertzian contact theory is investigated in order to reduce the contact stress. The optimal design is performed using the simple 2-D finite element model and its results are verified by 3-D finite element analysis.

• Journal of Electrical Engineering and Technology
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• v.13 no.5
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• pp.2033-2044
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• 2018

This study presents states-of-the art overview of the system level electrostatic discharge (ESD) analysis and testing. After brief description of ESD compliance standards and ESD coupling mechanisms, the study provides an in-depth review and comparison of the various techniques for the system level ESD coupling analysis using time and frequency domain techniques, full wave electromagnetic modeling and hybrid modeling. The methods used for improving system level ESD testing using troubleshooting and determining the root causes of soft failures, the optimization of ESD testing and the countermeasures to mitigate ESD problems are also discussed.

• Bulletin of the Korean Chemical Society
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• v.26 no.12
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• pp.2033-2037
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• 2005

In vitro selection was used to isolate $Mg^{2+}$-dependent self-cleaving ribozymes with cis-cleavage activity from a pre-tRNA library having 40-mer random sequences attached to 5'-end of E. coli $tRNA^{Phe}$. After 8 rounds of SELEX (Systematic Evolution of Ligands by Exponential Enrichment), RNA molecules which can self-cleave at the high concentration of $Mg^{2+}$ were isolated. The selected ribozymes can carry out the self-cleavage reaction in the presence of 100 mM $Mg^{2+}$ but not in 10 mM $Mg^{2+}$. The cleavage sites of the ribozymes are located at +3 and +4 of $tRNA^{Phe}$, compared with +1 position of 5'-end cleavage site of pre-tRNA by RNase P. New RNA constructs deprived of its D stem-loop, anticodon stem-loop, variable loop and T stem-loop, respectively showed the cleavage specificity identical to a ribozyme having the intact tRNA structure. Also, the new ribozyme fused with both a ribozyme and $tRNA^{Leu}$ showed the cleavage activities at the various sites within its sequences, different from two sites of position +3 and +4 observed in the ribozyme with $tRNA^{Phe}$. Our results suggest that the selected ribozyme is not structural-specific for tRNA.

• The Journal of the Korean Society for Microbiology
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• v.11 no.1
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• pp.19-22
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• 1976

The authors identified 436 Salmonella cultures, which were 426 Salmonella typhi and ten cultures of other serotypes among 2033 suspectable enteric pathogens collected from all over the country in 1975.

• Transactions of the Korean Society of Mechanical Engineers
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• v.17 no.8
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• pp.2033-2042
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• 1993

In conventional SCC susceptibility test, there are constant strain test, constant load test, slow strain rate test(SSRT) and K$_{ISCC}$ test. Among them, the SSRT method is much more aggressive in producing SCC than the other tests, so that the test time of it is considerably reduced. But this SSRT method has mostly been worked using the uniaxial tensile specimen untill now. Therefore, the SSRT method using the tensile specimen(Ten-SSRT) has much difficulty in SCC susceptibility evaluation of a localized region like weldment and the advantage material of high order. Recentely, the small punch(SP) test method using miniaturized small specimen is the very effective test method for fracture strength evaluation of a localized region like weldment and fusion reactor wall irradiated in the nuclear power plant. This paper investigated the possibility of SCC susceptibility evaluation by the SP-SSRT method using the miniaturized small specimen. Therefore, we obtained the result that the SP-SSRT had the possibility for the evaluations of SCC susceptibility for shorter time to corrosive environment compare to Ten-SSRT which was conventional method.