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Studies on Tolerance of Mice to X-rays (X-선에 대한 마우스의 내력)

  • 김정진
    • The Korean Journal of Zoology
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    • v.6 no.2
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    • pp.11-15
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    • 1963
  • A total of 220 adult male mice (18-20g) of the S.M. strain were divided into ten experimental and control groups. The total-body X-ray irradiation doses used were 50 r, 100r, 200r, 400r, 600r, 800r, 1,000r, 1,200r, 1,400r, and1,600r. The respiratory arrest (mortality) caused by each irradiation doses were observed for 30 days. Relationships between irradiation doses and survival time and percentage of response were examined. From this experiment, a formula was obtained to express the relationship among three factors, which may be presented as follows : {{{{{{{{P= { 10} over { SQRT { 2 pi } } INT _{ - INF }^{ p'} e-{(p'-50)^2 } over {200 }dp···(a) p'=100 LEFT { t^0.3- LEFT ( { { 16.9965} over {D-60 } } RIGHT ) ^{ { 1} over {2.5 } } } / LEFT { LEFT ( { 26372.43} over {D-81.86 } RIGHT ) ^{ { 1} over {2.5 } } -( { { 16.9965} over {D-60 } } RIGHT ) ^{ { 1} over {2.5 } } ···(b) p= { (D-60) t^0.75-16.9965} over {0.2186 t^0.75 +263.55434 }····(c) }} {{{{P= { 10} over { SQRT { 2 pi } } INT _{ - INF }^{ p'} e-{(p'-50)^2 } over {200 }dp···(a) p'=100 LEFT { t^0.3- LEFT ( { { 16.9965} over {D-60 } } RIGHT ) ^{ { 1} over {2.5 } } } / LEFT { LEFT ( { 26372.43} over {D-81.86 } RIGHT ) ^{ { 1} over {2.5 } } -( { { 16.9965} over {D-60 } } RIGHT ) ^{ { 1} over {2.5 } } ···(b) p= { (D-60) t^0.75-16.9965} over {0.2186 t^0.75 +263.55434 }····(c)

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A Study on the Analysis and Design of 16-BIT ALU by Using SPICE (SPICE를 이용한 16-BIT ALU의 회로 해석 및 설계에 관한 연구)

  • 강희조
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.15 no.3
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    • pp.197-212
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    • 1990
  • This paper present a new design concept of a single chip 16-bit data path using the concept of modular design, the whole system is divided into several blocks which can be operated as an independent system itself. Making the internal blocks can act as a subsystem, it is possible to shorten design turn-around time, to be redesigned effectively, and to optimize the system performance. The designed system is data path. The data path is to manipulate 16-bit integer data. It is composed of aritmetic logic unit, register file, barrel shifter and bus circuit. The widths and lengths of gate in the circuit were determined using SPICE2. The results of circuit simulation were in good agreement with expected circuit characteristics.

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Walkability on Ramps by Gait Analysis (보행자세해석에 의한 경사로의 보행성)

  • 유남형
    • Journal of the Korean Institute of Landscape Architecture
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    • v.23 no.2
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    • pp.157-166
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    • 1995
  • To investigate walkability of ramps, walking patterns of 18 healthy adults,12 aged 20 to 26 and 6 aged 68 to 76,were studied at free,rhythm constrained walking up or down ramp using goniometer and footswitch Ramp inclinations were set 4,8,12,16,20 degrees. The results were as follows. 1)The step length of subjects were decreased significantly in12$^{\circ}C$′or 16′free downramp walking. With regard to step length, some subject groups walked abnormally in 16" or 20" ramp walking 2) The step width of subjects were increased significantly in 12" or 16" ramp walking. 3) The cadence duration of some subject groups were increased in 12" upramp walking. 4) The double stance duration and double stance ratio of some subject groups were increased significantly in 8",12", or 16"upramp walking. 5) The maximum knee flexion angle of stance phase were increased in 12" ramp walking. 6)Most temporal parameters and spatial parameters of gait were increased or decreassd greatly between 4" ramp and 8" ramp or between 8′ramp and 12′ramp. But statistics significancy were not recognized 7) The results suggest that ramp inclination less than 8′(14%) -12′(21%) is desirable for the normal gait the ramp inclination must not exceed 16" -20" in unavoidable circumstances.

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A Study on Flicker Free LED Driver for Dimming MR16 Electronic Transformer (조광기용 MR16 안정기 호환 Flicker Free LED 구동회로 연구)

  • Kim, Taek-Woo;Hong, Sung-Soo;Yeom, Bong-Ho
    • The Transactions of the Korean Institute of Power Electronics
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    • v.19 no.4
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    • pp.327-331
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    • 2014
  • LED(Light Emitting Diode) is a semiconductor device utilizing electroluminescent effect is a phenomenon in which a type of P-N junction diode, the light of short wavelength which a voltage is applied in the forward direction is released. LED is advantageous in reducing the energy as environmentally materials that can greatly reduce the carbon emissions, recent it has attracted attention IT(Information Technology) and GT(Green Technology) industry. In addition, there are advantages long life, high efficiency, and excellent response speed, LED have come into the spotlight as the illumination means to replace the existing fluorescent light and incandescent light bulb. When connecting to MR16 electronic transformer for existing LED driver circuit, due to malfunction of the dimmer and the electronic transformer, flicker occurs and linear dimming is not possible. Therefore, in this paper, we suggest an LED drive circuit there is no flicker with the corresponding dimming MR16 electronic transformer. Further, we explain the principles of the LED current control technique and the principle of the drive circuit of the LED, in order to validate the proposed circuit through prototyping and simulation.

Characterization of Lactobacillus plantarum strains isolated from black raspberry and their effect on BALB/c mice gut microbiota

  • Choi, Hye Ran;Chung, Yi Hyung;Yuk, Hyun-Gyun;Lee, Hyunki;Jang, Han Su;Kim, Yosum;Shin, Daekeun
    • Food Science and Biotechnology
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    • v.27 no.6
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    • pp.1747-1754
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    • 2018
  • The objective of this study was to evaluate probiotic effects of two Lactobacillus plantarum strains (GBL16 and 17) isolated from black raspberry. Results revealed that the number of GBL16 was gradually decreased as bile salt concentration was increased from 0.3 to 1%. However, GBL17 did not show any difference when GBL17 was applied to 1% bile salt, and it indicates that GBL17 is more tolerant to bile salt than GBL16. GBL17 exhibited higher heat resistance and adhesion ability to Caco-2 cells than GBL16. Regarding gut microbiome, no significant change in the number of total bacteria in intestines of mice after treatment with GBLs was determined. However, the combination of GBL16 and GBL17 significantly increased the number of total bacteria in intestines of mice after they were orally administered. Therefore, the results suggest that both GBL16 and 17 strains could be one of major probiotics that can improve human gut health.

Stability Studies of Divalent and Trivalent Metal Complexes with 1,7,13-Trioxa-4,10,16-triazacyclooctadecane-N,$N^{\prime},N^{\prime}^{\prime}$-tri(methylacetic acid)

  • 홍춘표;김동원;최기영
    • Bulletin of the Korean Chemical Society
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    • v.18 no.11
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    • pp.1158-1161
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    • 1997
  • The potentiometric methods have been used to determined the protonation constants (logKiH) for the synthesized 1,7,13-trioxa-4,10,16-triazacyclooctadecane-N,N',N''-tri(methylacetic acid) [N3O3-tri(methylacetic acid)] and the stability constants (logKML) of the complexes of divalent and trivalent metal ions with the ligand N3O3-tri(methylacetic acid). The protonation constants of N3O3-tri(methylacetic acid) were 9.70 for logK1H, 9.18 for logK2H, 7.27 for logK3H, 3.38 for logK4H, and 2.94 for logK5H. The stability constants for the complexes of divalent metal ions with N3O3-tri(methylacetic acid) were 10.39 for Co2+, 10.68 for Ni2+, 13.45 for Cu2+, and 13.00 for Zn2+. The order of the stability constants for the complexes of the divalent metal ions with N3O3-tri(methylacetic acid) was Co2+ < Ni2+ < Zn2+ < Cu2+. The stability constants for the complexes of trivalent metal ions with N3O3-tri(methylacetic acid) were 16.20 for Ce3+, 16.40 for Eu3+, 16.27 for Gd3+, and 15.80 for Yb3+. The results obtained in this study were compared to those obtained for similar ligands, 1,7-dioxa-4,10,13-triazacyclopentadecane-N,N',N"-tri(methylacetic acid) and 1,7,13-trioxa-4,10,16-triazacyclooctadecane-N,N',N"-triacetic acid, which have been previously reported.

Inhibitory Effect of Kaurane Type Diterpenoids from Acanthopanax koreanum on TNF-$\alpha$ Secretion from Trypsin-Stimulated HMC-1 Cells

  • Cai, Xing-Fu;Shen, Guanghai;Dat, Nguyen-Tien;Kang, Ok-Hwa;Lee, Young-Mi;Lee, Jung-Joon;Kim, Young-Ho
    • Archives of Pharmacal Research
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    • v.26 no.9
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    • pp.731-734
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    • 2003
  • Five known kaurane type diterpenoids, 16$\alpha$H, 17-isovaleryloxy-ent-kauran-19-oic acid (1), 16$\alpha$-hydroxy-17-isovaleryloxy-ent-kauran-19-oic acid (2), paniculoside-IV (3), 16$\alpha$-hydroxy-ent-kauran-19-oic acid (4), and ent-kaur-16-en-19-oic acid (5) were isolated from the root of Acanthopanax koreanum by repeated column chromatography and reversed phase preparative HPLC. The structures of these compounds were established from physicochemical and spectral data. Among the isolated compounds 16$\alpha$H, 17-isovaleryloxy-ent-kauran-19-oic acid (1) showed potent inhibitory activity ($IC_50$ value, 16.2 $\mu$ M) on TNF-$\alpha$ secretion from HMC-1, a trypsin-stimulated human leukemic mast cell line.

A Study of Relation Between Yamanaka Hardness and Penetrometer Cone Index (토양 경도 측정방법간 비교연구)

  • Han, Kyung-Hwa;Cho, Hee-Rae;Jeon, Sang-Ho;Zhang, Yong-Seon
    • Korean Journal of Soil Science and Fertilizer
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    • v.44 no.3
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    • pp.344-346
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    • 2011
  • This study was conducted in order to compare between Yamanaka hardness (YA), hand-push type, and penetrometer cone index (PE), on 16 upland sites. Yamanaka hardness had significant correlation with penetrometer cone index. The regression equation was $PE=1.80^*YA+0.16$ ($R^2=0.91^{***}$, N=16) with the applicative YA range of 0.1-1.3 MPa.

Changes in the Contents of Phenolic Components in the Stem of Acanthopanax koreanum Depending on Extracting Batches (섬오가피의 추출 조건에 따른 페놀성 성분 함량 변화)

  • Kim, Sung Gi;Lee, Jae Bum;Cho, Soon Hyun;Ko, Sung Kwon
    • Korean Journal of Pharmacognosy
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    • v.50 no.2
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    • pp.124-132
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    • 2019
  • This study compared the contents of phenolic components depending on the extracting conditions of Acanthopanax koreanum stem to provide basic information for developing Acanthopanax koreanum-based functional foods. Our findings show that the content of total phenolic component peaked at 16 hours of extraction (WAK-16, 7.22%) and when water extracted at $100^{\circ}C$. However, 11-hours water extraction (WAK-11) showed highest eleutheroside B concentration of 1.32%, a main component of A. koreanum, and the level of chlorogenic acid concentration was the highest when 1-hour water extraction (WAK-1) was conducted, being 2.12%. Moreover, highest concentration of eleutheroside E was observed in 16-hours water extraction (WAK-16) as 1.49%. With 60-hours water extraction (WAK-60), the content of syringaresinol, an active phenolic aglycon substance, concentration was the highest with the value of 0.10%. Isofraxidin showed the highest concentration of water extract(0.09%) for 20 hours (WAK-20) and 0.42% for sinapyl alcohol[16 hours (WAK-16)].

DNA Barcoding of Benthic Ragworms of the Genus Nectoneanthes (Polychaeta: Nereididae) Collected in Korean Waters

  • Park, Taeseo
    • Animal Systematics, Evolution and Diversity
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    • v.37 no.3
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    • pp.235-241
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    • 2021
  • To provide better taxonomic information of the genus Nectoneanthes, the two DNA barcode regions of mitochondrial cytochrome c oxidase subunit I (COI) and 16S ribosomal DNA (rDNA) sequences of Nectoneanthes oxypoda and N. uchiwa were determined. In addition, the respective sequences of four nereidid species closely related to Nectoneanthes were retrieved from GenBank for comparison and to estimate intra- and inter-specific genetic distances. The aligned sequence lengths of COI and 16S rDNA were 570 bp and 419 bp long, respectively. The mean intraspecific variation in both markers was less than 1% in all species except for that in COI of H. diadroma (1.87%). The mean interspecific variation between N. oxypoda and N. uchiwa was 12.02% regarding COI and 1.85% regarding 16S rDNA. In contrast, the mean interspecific variation between species of other genera was comparably higher(i.e., genus Perinereis: 20.5% in COI and 8.3% in 16S rDNA; genus Hediste: 13.18% in COI and 2.64% in 16S rDNA), compared with that between the two Nectoneanthes species. This result indicated that these Nectoneanthes species are genetically more closely related than other congeneric species of different genera. The DNA barcoding information on Nectoneanthes species generated in this study provides valuable insights for further biodiversity studies on nereidid species.