• Journal of Pharmaceutical Investigation
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• v.39 no.5
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• pp.345-351
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• 2009

Organic cation transporters (OCTs) are important for absorption, elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. This gene is located in a cluster on chromosome 6 and OCTs are in major organs such as intestine, liver, kidney, brain and placenta. Therefore, expression levels and function of OCTs directly affect plasma levels and intracellular concentrations of drugs and thereby determine therapeutic response. The aim of this study was to investigate the frequency of the SNPs on OCT1 (C181T and C1022T) and OCT2 (G808T) to analyze haplotype frequency in healthy Korean population. Human subjects have been genotyped for OCT1 (C181T for 195 subjects and C1022T for 825 subjects), using polymerase chain reaction-based diagnostic tests (RFLP). And for OCT2 (G808T), a total of 861 subjects have been genotyped, using pyrosequencing method. Haplotype was statistically inferred using an algorithm based on the expectation-maximization (EM). OCT1 C181T genotyping showed 100% homozygous wild-type (C/C). OCT1 C1022T genotyping showed wild-type (C/C), heterozygous (C/T) and homozygous mutant-type (T/T) and each accounted for 72.1, 24.5 and 3.4%, respectively. OCT2 G808T genotyping results also showed homozygous wild-type (G/G), heterozygous (G/T) and homozygous mutant-type (T/T) and each took 81.8, 17.9 and 0.3%, respectively. Based on these genotype data, haplotype analysis between OCT1 C181T and OCT1 C1022T has proceeded. The result has revealed that linkage disequilibrium between alleles is not obvious (P=0.0122).

• International Journal of Highway Engineering
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• v.15 no.6
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• pp.93-101
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• 2013

PURPOSES : The rumble strip installed at the highway near the tollgate has the purpose to reduce the vehicle velocity or prevent sleepiness by awakening people to the danger. These rumble strip has different vibration decibel from the rumble strip shapes, resulting in some fatigue damage to human because a driver suffers from a lot of stress and displeasure. In this connection, the objective of this paper is to analyze the vibration decibel perceived by a driver in the vehicle under some conditions. METHODS : The vibration decibel conveyed from the tire can be analyzed. The frequency analysis methods were used according to DFT (Discrete Fourier Transform) analysis, FFT (Fast Fourier Transform) analysis, CPB (Constant Percentage Bandwidth) analysis. But the frequency analysis method in this paper is the 1/24 OCT(Octave) band analysis because of the convenience of the analysis and the overall vibration amplitude along the frequency. RESULTS : By using the results of the vibration decibel after analyzing the 1/24 OCT band analysis, these results can be compared from some conditions (e.g., rumble strip shape, uniform velocity of a vehicle, road condition, mass of a vehicle). As a result, the numerical values of decibel are not directly proportional to the vehicle velocity. CONCLUSIONS : At the condition that a vehicle is passing by the rumble strip, the value of a vibration decibel at the rumble strip of the cylinder shape is smaller than the rumble strip of rectangular shape regardless of the rumble strip depth and width. At the mass condition, the more a vehicle is massive, the more the vibration decibel increases. At the road condition, the vibration decibel at the wet road is smaller than the value at dry road condition.

• Restorative Dentistry and Endodontics
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• v.47 no.1
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• pp.10.1-10.11
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• 2022

Objectives: This study aimed to investigate the color stability, solubility, and surface characteristics of 3 calcium silicate-based cements (CSCs) after immersion in different solutions. Materials and Methods: ProRoot white mineral trioxide aggregate (MTA), Biodentine, and Endosequence Root Repair Material (ERRM) were placed in cylindrical molds and stored at 37℃ for 24 hours. Each specimen was immersed in distilled water, 5% sodium hypochlorite (NaOCl), 2% chlorhexidine, or 0.1% octenidine hydrochloride (OCT) for 24 hours. Color changes were measured with a spectrophotometer. Solubility was determined using an analytical balance with 10^-5 g accuracy. The surface characteristics were analyzed using scanning electron microscopy and energy-dispersive spectroscopy. Data were analyzed using 2-way analysis of variance, the Tukey test, and the paired t-test. Results: MTA exhibited significant discoloration in contact with NaOCl (p < 0.05). White precipitation occurred on the surfaces of Biodentine and ERRM after contact with the solutions, and none of the materials presented dark brown discoloration. All materials showed significant solubility after immersion in the solutions (p < 0.05), irrespective of the solution type (p > 0.05). The surface topography and elemental composition of the samples showed different patterns of crystal formation and precipitation depending on the solution type. Conclusions: All materials presented some amount of solubility and showed crystal precipitation after contact with the solutions. Biodentine and ERRM are suitable alternatives to ProRoot MTA as they do not exhibit discoloration. The use of OCT can be considered safe for CSCs.

• Journal of Chest Surgery
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• v.28 no.12
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• pp.1167-1173
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• 1995

We evaluated fifty three cases of traumatic diaphragmatic injuries that we have experienced from Jan.1973 to Oct.1994. The age distribution of the pateint was ranged from 1 to 74 years. Sex ratio is 39:14 with male dominence. The traumatic diaphragmatic injuries were due to blunt trauma in 37[Left 22, Right 15 cases and penetrating trauma in 16[Left 9, Right 7 cases. In blunt trauma, Preoperative diagnosis of the diaphragmatic injuries was possible in 27 patients[72% , and in penetrating trauma, 14 patients[88% . Among 37 in blunt traumas, 22[58% cases, and among 16 in penetrating traumas, 13[88% cases were operated within 24 hours. The most common herniated abdominal organ in the thorax was stomach[14/53 . The traumatic diaphragmatic repair of 50 cases were performed by thoracic approach in 23 cases, thoracoabdominal approach in 8 cases and abdominal approach in 19 cases, and in 3 cases, not operated. Hospital mortality [including not operated patients[3 was 17%[9/53 and the causes of death were intracranial hematoma[1 , hypertensive encephalopathy[1 and asphyxia[1 , and among operated patients[6 , combined head injury[2 , multiorgan failure[2 , hypovolemic shock[1 , and pulmonary edema & renal failure[1 . All deaths had related to the severity of associated injuries.

• The Journal of Korean Society for School & Community Health Education
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• v.23 no.2
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• pp.39-50
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• 2022

Objectives: This study aimed to confirm the association between self-determination and self-directed learning among Korean nursing students, as well as the mediating effect of academic self-efficacy. Methods: Data from 139 nurse students were surveyed in this descriptive cross-sectional study. They were collected from Oct 1 to 30, 2020, using self-report questionnaires. The collected data were analyzed using descriptive statistics, independent t-test, one-way analysis of variance, Scheffé test, Pearson's correlation coefficient analysis, and mediated model for PROCESS macro using the SPSS/WIN 24.0. Results: Self-directed learning was positively associated with self-determination (r=.56, p<.001) and academic self-efficacy (r=.63, p<.001). Furthermore, academic self-efficacy had a mediating effect on the relationship between self-determination and self-directed learning (B=0.21, 95% CI=0.12~0.32). Conclusion: The impact of self-determination on the self-directed learning among nursing students was mediated by academic self-efficacy. Therefore, these results provide important data for future self-directed learning in nursing education.

• Journal of the Korean Dietetic Association
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• v.24 no.3
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• pp.212-230
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• 2018

The purpose of this study was to investigate the effects of job stress on job satisfaction according to interpersonal relationship type among school dieticians and nutrition teachers. The online survey was conducted from Oct. 26th to Nov. 7th, 2017 in 2,000 randomly selected dieticians and nutrition teachers in the capital area. A total of 453 collected questionnaires were used for analysis. SPSS v.21.0 Statistical Package Program was used for the statistical process. For the results regarding interpersonal relationship type of dieticians, open-type (73.3%) was the highest, followed by self-assertive-type (23.0%), isolated-type (2.6%), and careful-type (1.1%). Regarding overall job satisfaction, 'human relation' was the highest, followed by 'job itself', 'working environment', and 'personal rating & welfare system', in that order. According to interpersonal relationship type, in the case of 'open-type' or 'careful-type', job satisfaction was relatively high. Regarding overall job stress, 'job demand' was the highest, followed by 'lack of reward', 'organizational system', 'interpersonal conflict', 'occupational climate', 'job insecurity', and 'insufficient job control', in that order. In accordance with interpersonal relationship type, overall job stress index was high in terms of 'self-assertive-type' or 'careful-type'. For the results of analyzing the correlation between job satisfaction and job stress index, all areas showed statistically significant negative correlations. Multiple regression analysis was performed to study the effects of job stress on job satisfaction mediating interpersonal relationship type. Job stress had different effects on job satisfaction in terms of 'open-type' and 'self-assertive type'. In conclusion, different strategies are needed for dieticians with different interpersonal relationship types to improve job satisfaction and to reduce job stress.

• Journal of The Korean Society of Grassland and Forage Science
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• v.24 no.1
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• pp.53-60
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• 2004

Recently, there has been a growing tendency to use whole crop rice for feeds as there is an increased rice supply and a decrease in the demand for rice in Korea. Little information, however, is available about the management and utilization of whole crop rice for feeds. This study was conducted to decide the optimum harvest date through examining the plant height, dry matter(DM) yield and feed composition of whole crop rice harvested at different maturity. Field study was established early in May until October 7th on a rice field at Yupori, Sinbuk-yeup, Chunchon, Kangwon-Do. "Ilpum" mutant rice was sown at 52 kg/ha, and N, P and K were applied at 209, 113 and 81 kg/ha, respectively. The rice was harvested at six different mature stages for analysis; booting stage; 17 Aug., milk-ripe stage; 27 Aug., dough stage; 7 Sep., yellow ripe stage; 17 Sep., dead ripe stage; 27 Sep. and full ripe stage; 7 Oct. Plant height was 77 cm in booting stage (P<0.05) which was lower when compared to the other stages among which the heights did not differ with average range of 93∼97 cm. The highest dry matter yield was observed in yellow ripe stage (22.8 T/ha), which was followed by dead ripe stage (19.3 T/ha), full ripe stage (19.3 T/ha), and dough stage (15.1 T/ha). Crude protein (CP) and Neutral detergent fiber (NDF) concentrations consistently decreased with maturity. The highest concentrations of CP and NDF were obtained in booting stage with 9 and 73.6%, respectively (P<0.05), and lowest in full ripe stage with 5.8 and 64.6%, respectively (P<0.05). The concentration of total digestible nutrient (TDN) was highest in booting stage (59.7%); however no significant difference was found among other stages. The concentrations of Ca and P were not different among mature stages. According to these results, the yellow ripe period is appropriate to harvest the whole crop rice for forage considering dry matter yields, feed compositions and TDN concentrations.

• Journal of the Korean Home Economics Association
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• v.47 no.1
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• pp.13-24
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• 2009

The purpose of this study was to examine the effects of banking service quality on consumer satisfaction and positive word-of-mouth. A total of 330 bank consumers were investigated between Sept. 11 and Oct. 11, 2006. After sorting through the data, the responses of 299 consumer ( > 24 yrs old) were used for analysis. SERVPERF, the performance component of the Service Quality scale (SERVQUAL), was used to measure the four dimensions of reliability, responsiveness/empathy, assurance, and tangibles. Responses were partitioned by age and gender. The major findings were as follows; The effect of service quality by SERVPERF on consumer satisfaction and positive word-of-mouth did not differ according to gender. However, positive recommendation in males was directy related to the technical quality evaluate. In females, higher the functional quality evaluate was directly related to higher positive word-of-mouth recommendation. The effect of service quality by SERVPERF on consumer satisfaction was not revealed differently according to age. However, with respect to respondents under the age of 45, tangibles and assurance had a positive relationship with word-of-mouth recommendation. Furthermore, the higher the functional quality evaluate, the higher the level of positive word-of-mouth. Responsiveness/empathy was the most significant factor on positive word-of-mouth recommendation in respondents over the age of 45. In this age group, the higher the technical quality evaluate, the higher the level of positive word-of-mouth recommendation. These results have implications for banking service managers, particularly in improving service quality to increase consumer satisfaction and positive word-of-mouth. Future research is needed to replicate this study using more broad and representative samples in order to test the generalization of these findings.

• Environmental Analysis Health and Toxicology
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• v.24 no.2
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• pp.149-157
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• 2009

In this study, recognized building-related health symptoms of various workers in dental college hospitals are surveyed and analyzed in order to improve indoor environment at dental college hospitals. We conducted a questionnaire survey for 682 workers in three dental college hospitals located in Seoul from Sep. 20 to Oct. 8, 2004. Most workers at dental hospitals complained about noise, poor ventilation, dusty environment, and air dryness. SBS symptoms score for subjects was 1.43${\pm}$0.74 (often feel) and major symptoms was throat, CNS, eye, and nose symptoms. Recognized Building-related health symptoms are significantly related to tasks, working experience, job-satisfaction, indoor environment recognition index, medical history, used to special material, and number of dental unit chair. Also working places and ventilation are significantly related to the symptom. Based on the results, it can be said that special dental treatment causes undesirable environment such as noise, dust, and bad odor. It is also related to recognized building related health symptoms reported by workers at dental hospitals. So managemental efforts are needed to improve indoor environment which is related by dental treatment.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.28 no.4D
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• pp.561-567
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• 2008

In this study, shoreline change was analyzed by RTK-GPS and advanced airborne LiDAR survey. For extraction of coastline, first of all, tide correction was conducted at all RTK-GPS points through the comparing with the corresponding tidal height, and cross section providing coastline was produced using Autocad Civil3D program. Comparing with two results of RTK-GPS (first, 29 Aug 2007; second, 6 Oct 2007) surveys, coastline of the first result had been decreased about 21m compare with that of the second. And it was also demonstrated that the length of coastline by the first RTK-GPS was 15m shorter than that by the airborne LiDAR survey (Dec. 2006). In addition, we recoquized that the erosion appeared in the top right-hand (dock area); the sediment in the bottom left-hand (Chosun beach area) of the Haeundae beach. As a result, therefore, it was learned that artificial sand filling for beach open and natural effects such as a typhoon, current drift, wind direction gave cause for area changes and coastline.