• Annals of Coloproctology
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• v.34 no.6
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• pp.286-291
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• 2018

Purpose: Stage-IIIC colon cancer is an advanced disease; however, its oncologic outcomes and prognostic factors remain unclear. In this study, we aimed to determine the predictors of disease-free survival (DFS) in patients with stage-IIIC colon cancer. Methods: From a multicenter database, we retrospectively enrolled 611 patients (355 men and 256 women) who had undergone a potentially curative resection for a stage-IIIC colon adenocarcinoma between 2003 and 2011. The primary endpoint was the 5-year DFS. Results: The median age was 62 years; 213 and 398 patients had right-sided colon cancer (RCC) and left-sided colon cancer (LCC), respectively. The 5-year DFS in all patients was 52.0%; median follow-up time was 35 months (range, 1-134 months). A multivariate Cox regression revealed that female sex (hazard ratio [HR], 1.50; 95% confidence interval [CI], 1.19-1.90; P < 0.01), right-sided tumor location (HR, 1.65; 95% CI, 1.29-2.11; P < 0.01), lymphatic invasion (HR, 1.52; 95% CI, 1.08-2.15; P < 0.01) and a high (${\geq}0.4$) metastatic lymph node ratio (HR, 3.72; 95% CI, 2.63-5.24; P < 0.01) were independent predictors of worse 5-year DFS. Female patients with RCC were 1.79 fold more likely to experience recurrence than male patients with LCC. Conclusion: Female sex and right-sided tumor location are associated with higher tumor recurrence rates in patients with stage-IIIC colon cancers. Aggressive treatment and close surveillance should be planned for patients in these groups.

• Clinical and Experimental Pediatrics
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• v.50 no.1
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• pp.65-73
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• 2007

Purpose : Short stature is an important complication that impairs the quality of life in survivors of childhood brain tumors. We studied their final adult height (FAH) to evaluate risk factors for short stature. Methods : We reviewed the medical data of 95 survivors of childhood brain tumors (64 males and 31 females) who had been followed up from 1982 to 2006, reached FAH, and had a more than five year-disease-free survival. Results : Final adult height standard deviation score (FAHTSDS: $mean{\pm}SD$) of the patients was lower than those of general population ($-1.15{\pm}1.72$), HTSDS at diagnosis ($-0.13{\pm}1.57$), and target HTSDS ($-0.49{\pm}0.69$). FAHTSDS of craniopharyngioma patients did not decrease ($0.57{\pm}1.17$), but those of germ cell tumor and medulloblastoma patients were significantly reduced ($-1.20{\pm}1.45$, $-2.70{\pm}1.46$; P<0.05). The patients treated with craniospinal radiation or chemotherapy had lower FAHTSDS ($-1.93{\pm}1.58$, $-2.27{\pm}1.44$; P<0.01). In the spinal irradiation group, the younger the age at diagnosis was, the more the loss of FAH (r=0.442, P<0.01). Growth hormone replacement (GHR) didn't improve FAHTSDS, but starting GHR under 12 years was an independent factor for improving FAH once treatment methods were taken into account (P=0.01). Conclusion : The younger age at diagnosis, spinal radiation and chemotherapy were all important risk factors of height loss, and height gain was expected in patients who received GHR under the age of 12 years. Therefore, regular check-ups of growth and early intervention with growth hormones are needed for high risk groups to improve FAH.

• Journal of Environmental Impact Assessment
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• v.26 no.6
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• pp.538-552
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• 2017

In this study, total mercury (THg) of Black-tailed Gull (Larus crassirostris) eggs laid on Baengnyeongdo, West Sea of Korea was analyzed in order to compare the THg concentrations of eggs depending on egg-laying order. The first-laid eggs ($mean{\pm}standard$ error, $234.4{\pm}11.2ng/g\;wet$, n=18, t=8.4, p<0.01) significantly had higher THg concentrations than the second-laid eggs ($182.8{\pm}9.1ng/g\;wet$, n=18). Also, the first-laid eggs had higher values in biometrics (length $63.10{\pm}0.49mm$, t=2.4, p<0.05; width $44.51{\pm}0.19mm$, t=4.3, p<0.01; weight $65.53{\pm}0.87g$, t=4.2, p<0.01) than the second-laid eggs (length $62.37{\pm}0.40mm$, width $43.55{\pm}0.17mm$, and weight $62.48{\pm}0.72g$). These differences might be attributed to the amount of food eaten by females relating to males' courtship feeding pattern (males increase courtship feeding rate before the first eggs are laid, and decrease the rate following the laying of the first eggs). Moreover, the lower food intake of females could diminish the quantities of egg albumen that contains a protein binds to most of methylmercury during the period of egg production. Therefore, it is necessary to consistently apply one of egg selection methods (targeted selection (the first-laid egg or the second-laid egg), random selection, and etc.) in one nest for ensuring comparability of mercury concentrations among monitoring sites and monitoring years.

• Korean Journal of Applied Biomechanics
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• v.25 no.4
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• pp.489-498
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• 2015

Objective : The purpose of this study was to analyze the effects of the windlass mechanism in trail-walking shoe prototypes that can effectively support arches. A study of these effects should help with the development of a first-rate trail-walking shoe development guide for the distribution of quality information to consumers. Methods : The subjects were ten adult males who volunteered to participate in the study. Shoes from three companies, which will be referred to as Company S (Type A), Company M (Type B), and Company P (Type C), were selected for the experiment. The subjects wore these shoes and walked at a speed of 4.2 km/h, and as they tested each shoe, the contact area, maximum pressure average, and surface force were all measured. Results : Shoe Type A showed a contact area of $148.78{\pm}4.31cm^2$, Type B showed an area of $145.74{\pm}4.1cm^2$, and Type C showed an area of $143.37{\pm}4.57cm^2$ (p<.01). Shoe Type A demonstrated a maximum average pressure of $80.80{\pm}9.92kPa$, Type B an average of $85.72{\pm}11.01kPa$, and Type C an average of $89.12{\pm}10.88bkPa$ (p<.05). Shoe Type A showed a ground reaction force of $1.13{\pm}0.06%BW$, Type B a force of $1.16{\pm}0.04%BW$, and Type C a force of $1.16{\pm}0.03%BW$ (p<.05). Conclusion : The Type A trail-walking shoe, which was designed with a wide arch from the center of the forefoot to the front of the rearfoot showed excellent performance, however, more development and analysis of the windlass mechanism for a variety of arch structures is still necessary.

• Journal of Animal Science and Technology
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• v.45 no.3
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• pp.443-454
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• 2003

This study was conducted to investigate the effects of dietary full-fat soybeans and linseed as fat sources on in vitro ruminal disappearances of dry matter and unsaturated fatty acids and fatty acids profile. The full-fat soybeans and linseed were high in linoleic acid (C18:2n-6) and $\alpha$-linolenic acid (C18:3n-3), respectively. The incubation times were 0, 3, 6, 12, 24, 48 and 72 h. After each time of incubation, medium digesta was lyophilized for analyzing its DM and fatty acids contents. DM disappearance was significantly higher in linseed treatment compared to full-fat soybeans treatment on 6 h (p<0.01), 12 h (p<0.05) and 24 h (p<0.01), but cumulative gas production was not significantly different between both treatments. Stearic acid (C18:0) content in medium digesta was increased in both soybeans and linseed as a result of complete biohydrogenation with increased incubation time and C18:0 and C18:1 contents of full-fat soybeans were significantly higher than those of linseed (p<0.05). The content of C18:2 and C18:3 in digesta of each treatment were decreased by biohydrogenation as incubation time was increased. The content of C18:2 in full-fat soybeans was significantly higher than that of linseed (p<0.05) while the content of C18:3 in linseed was significantly higher than that of full-fat soybeans (p<0.001). Net C18:0 production was significantly higher in full-fat soybeans (332.24%) than linseed (133.16%) on 72 h. Disappearance of C18:1 was significantly lower in full-fat soybeans than linseed (p<0.05), especially full-fat soybeans showed negative (-) values on 3, 6, 12 and 24 h. The disappearance of C18:3 was significantly higher in linseed than full-fat soybeans (p<0.05). The disappearance of C18-unsaturated fatty acid was significantly higher in linseed than full-fat soybeans. In conclusion, polyunsaturated fatty acid (PUFA) in both full-fat soybeans and linseed were extensively biohydrogenated. In addition, biohydrogenation of PUFA was more completed to C18:0 in full-fat soybeans than linseed, reflecting dietary PUFA composition.

• Journal of the Microelectronics and Packaging Society
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• v.30 no.4
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• pp.91-97
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• 2023

Electrochemical (EC) CO₂ reduction is a promising method to convert CO₂ into valuable hydrocarbon fuels and chemicals ecofriendly. Here, we report on a facile method to synthesize surface-controlled SnO₂/Cu(OH)₂ nanowires (NWs) and its EC reduction of CO₂ to HCOOH and CO. The SnO₂/Cu(OH)₂ NWs (-16 mA/cm²) showed superior electrochemical performance compared to Cu(OH)2 NWs (-6 mA/cm²) at -1.0 V (vs. RHE). SnO₂/Cu(OH)₂ NWs showed the maximum Faradaic efficiency for conversion to HCOOH (58.01 %) and CO (29.72 %). The optimized catalyst exhibits a high C1 Faradaic efficiency stable electrolysis for 2 h in a KHCO₃ electrolyte. This study facilitates the potential for the EC reduction of CO₂ to chemical fuels.

• Journal of the Korean Society of Food Science and Nutrition
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• v.43 no.1
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• pp.74-79
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• 2014

The purpose of this study was to determine the efficacy of Aster koraiensis Nakai as a natural health food source. To accomplish this, the general and antioxidative contents of A. koraiensis were measured. Total contents of carbohydrates, crude protein, crude lipid, and ash were 72.15%, 13.49%, 5.09%, and 9.27%, respectively. Caloric content of A. koraiensis was 349.70 kcal, while total dietary fiber was 49.79%. Total proteins consisted of 18 different kinds of amino acids. Contents of essential and non-essential amino acids were 4.6 and 5.5 g/100 g, respectively. Regarding mineral contents, P was the most abundant mineral, followed by K, Ca, and Na. Therefore, A. koraiensis is an alkali material. Total phenol contents of the hot water and 80% ethanolic extracts of A. koraiensis were $87.7{\pm}5.01$ and $112.4{\pm}3.41$ mg GAE/g, respectively. Total flavonoid contents of the hot water and 80% ethanolic extracts were $86.6{\pm}3.71$ and $95.1{\pm}8.00$ mg RE/g, respectively. The DPPH radical-scavenging activity and reducing power of the 80% ethanolic extract of A. koraiensis were higher than those of the water extract. Therefore, the general nutrients and antioxidant bioactive materials in A. koraiensis are potential materials for health foods.

• Women's Health Nursing
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• v.3 no.1
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• pp.39-50
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• 1997

To examine the effects of an educational program with a purpose of reducing symptoms and ailments of women's premenstrual syndrome on the basis of the Self-care theory of Orem, a stimulation was carried out by using pre-and post-design of non-equity control group after choosing both an experimental group of 62 persons and a control group of 62 persons among 497 industrial women. This study was conducted from June 20, 1996 to September 30, 1996. Meantime, an education was provided for the experimental group of 62 persons for 8 weeks but no education for the control group of 62 persons. Study matters are general and obstetric characteristics, knowledge and self-care behavior and premenstrual syndrome from questionnaires with 497 industrial women, pre and post questionnaires with the control group of 62 persons and the questionnaires collected before and after providing an education for the experimental group of 62 persons, these matters were used as research data for this study and analyzed by means of the SAS program. As a result, it was shown that the scores of 497 industrial women's knowledge by age were the highest 26.36 for 20 to 29 year old women, then 25.58 for 30 to 39 year old women and 25.74 for less 19 year old women. The performance scores of their self-care behavior by age were the highest 39.17 for 30 to 39 year old women, 35.72 for 20 to 29 year old women and 32.85 for less 19 year old women, which means that the older the women are, the higher the performance degree is(p<0.01). And the scores of their premenstrual syndrome by age were 2.80 for less 19 year old women, 2.18 for 20 to 29 year old women and 2.00 for 30 to 39 year old women. Women in their teens and twenties showed more serious symptoms and ailments of premenstrual syndrome than women in their thirties(p<0.01). For the experimental group of 62 persons who received the educational program, both the knowledge of premenstrual syndrome and the degree of self-care behavior were remarkably improved(p<0.01), respectively and the symptoms and ailments of premenstrual syndrome were also remarkably reduced(p<0.01), while the control group showed no change in the knowledge, self-care behavior, and symptoms and ailments of premenstrual syndrome. The above results demonstrated that educational program based on the Self-care theory of Orem is an effective intervention to reduce the symptoms and ailments of premenstrual syndrome. The effects of the study can be generalized by extending the application in which various age groups and professional and social environments are considered together with a research to evaluate the long-term effects of this educational program. Accordingly, it is expected that it can possible not only to provide help for the women by actually applying the program to practical areas for improvement of women's health but also to suggest plans to activate it as one of health education areas.

• Journal of Korean society of Dental Hygiene
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• v.12 no.2
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• pp.335-343
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• 2012

Objectives : The aim of this investigation was to evaluate the remineralization effect of Bamboo salt and NaF+Bamboo salt solutions on bovine enamel formed incipient artificial enamel caries by microcomputed tomography (micro CT). Methods : Experimental solutions were distilled water(negative control), 2% sodium fluoride solution (2% NaF group), 3% bamboo salt solution (3% BS group) and the solution mixed 2% sodium fluoride solution and 3% bamboo salt solution (2% NaF+3% BS group). Specimens were prepared from extracted bovine teeth and divided into 4 groups of 10 specimens each by randomized blocks according to density. Then the specimens surface were divided equally into three parts to observe sound enamel area, incipient enamel carious area and remineralized enamel area. Only one-third of specimen surface was coated with nail varnish and these were exposed to a lactate carbopol buffer system for 72 hours. Then one-half of the demineralized enamel area was coated with nail varnish. The specimens were carried out under pH cycling model for 14 days as follows; samples were immersed in each experimental solution for 2 mins 3 times per day, demineralized for 4 hours and in mixed saliva for the remaining hours. After pH cycling, density was measured using micro CT. Results : All experimental groups showed remineralization effects except for negative control group(p<0.05). The differences of density after experimental solution treatment were statistically significant difference among 4 groups (p<0.01). The density difference values of groups were $0.04{\pm}0.01$ in negative control group, $0.19{\pm}0.01$ in 2% NaF group, $0.14{\pm}0.01$ in 3% BS group, and $0.21{\pm}0.01$ in 2% NaF+3% BS group. Conclusions : The bamboo salt solution showed remineralization effects on incipient artificial enamel caries and the solution mixed sodium fluoride solution and bamboo salt solution showed more remineralization effects than the bamboo salt solution. Thus, it is suggested that bamboo salt can be used as remineralization agent in incipient enamel caries lesion.

• Journal of Periodontal and Implant Science
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• v.24 no.3
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• pp.618-632
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• 1994

The ultimate goal of periodontal therapy is promoting the regeneration of lost periodontal tissue. The purpose of this study is to evaluate the effect of treatment using decalcified freeze dried bone allograft as a bone graft material. 47 intrabony defects from 27 patients with clinical diagnosis of chronic periodontitis were selected among those 24 defects were treated via flap operation only and designated as the control group, the other 23 defects were treated with decalcified freeze dired bone allografting via flap operation and designated as the experimental group. Clinical parameters including probing depth, loss of attachment, probing bone level and gingival recession have been recorded at 6th months, and the significance of the changes has been analyzed. The results are as follows : 1. Probing depths were reduced significantly in both control group($2.75{\pm}0.99mm$) and experimental group($3.69{\pm}0.97mm$) postoperatively(p<0.01). Experimental group showed significantly higher decrease compared to the control group(p]0.01). 2. Loss of attachment showed statistically significant decrease in both control group($1.77{\pm}1.08mm$) and experimental group postoperatively($2.70{\pm}1.55mm$). Experimental group showed significantly higher decrease compared to the control group(p]0.05). 3. Probing bone levels were reduced with statistically significance in both control group($1.08{\pm}0.97mm$) and experimental group($4.00{\pm}1.41mm$) postoperatively(p<0.01). Experimental group showed significantly higher decrease compared to the control group(p<0.01). 4. Gingival recession showed statistically significant increase in the control group($1.21{\pm}0.72mm$) and experimental group($1.00{\pm}1.09mm$) postoperatively(p<0.01). There was no statistical significance between the control group and the experimental group. On the basis of these results, treatment using allogenic decalcified freeze dried bone is effective in reducing probing depth, loss of attachment and probing bone level. Therefore allogenic decalcified freeze dried bone is an effective bone graft material in periodontal regeneration.