• Title/Summary/Keyword: 효용성평가

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Efficacy of a Respiratory Training System on the Regularity of Breathing (호흡연습장치를 적용한 호흡교정법의 영향 평가)

  • Shin, Eun-Hyuk;Park, Hee-Chul;Han, Young-YIh;Ju, Sang-Gyu;Shin, Jung-Suk;Ahn, Yong-Chan
    • Radiation Oncology Journal
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    • v.26 no.3
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    • pp.181-188
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    • 2008
  • Purpose: In order to enhance the efficiency of respiratory gated 4-dimensional radiation therapy for more regular and stable respiratory period and amplitude, a respiration training system was designed, and its efficacy was evaluated. Materials and Methods: The experiment was designed to measure the difference in respiration regularity following the use of a training system. A total of 11 subjects (9 volunteers and 2 patients) were included in the experiments. Three different breathing signals, including free breathing (free-breathing), guided breathing that followed training software (guided-breathing), and free breathing after the guided-breathing (post guided-breathing), were consecutively recorded in each subject. The peak-to-peak (PTP) period of the breathing signal, standard deviation (SD), peak-amplitude and its SD, area of the one cycle of the breathing wave form, and its root mean square (RMS) were measured and computed. Results: The temporal regularity was significantly improved in guided-breathing since the SD of breathing period reduced (free-breathing 0.568 vs guided-breathing 0.344, p=0.0013). The SD of the breathing period representing the post guided-breathing was also reduced, but the difference was not statistically significant (free-breathing 0.568 vs. guided-breathing 0.512, p=ns). Also the SD of measured amplitude was reduced in guided-breathing (free-breathing 1.317 vs. guided-breathing 1.068, p=0.187), although not significant. This indicated that the tidal volume for each breath was kept more even in guided-breathing compared to free-breathing. There was no change in breathing pattern between free-breathing and guided-breathing. The average area of breathing wave form and its RMS in postguided-breathing, however, was reduced by 7% and 5.9%, respectively. Conclusion: The guided-breathing was more stable and regular than the other forms of breathing data. Therefore, the developed respiratory training system was effective in improving the temporal regularity and maintaining a more even tidal volume.

Detection of Cancer with PET and PET/CT in Asymptomatic Volunteers (무증상 성인에서 PET과 PET/CT를 이용한 암 진단)

  • Chung, Ji-In;Cho, Han-Byoul;Shim, Jae-Yong;Choi, Joon-Young;Lee, Kyung-Han;Kim, Byung-Tae;Choi, Yoon-Ho
    • Nuclear Medicine and Molecular Imaging
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    • v.43 no.6
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    • pp.526-534
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    • 2009
  • Purpose: We retrospectively investigated the diagnostic performance of $^{18}F$-fluorodeoxyglucose positron emission tomography (PET) and PET/CT for cancer detection in asymptomatic health-check examinees. Materials and Methods: This study consisted of 5091 PET or PET/CT conducted as part of annual health examination at one hospital from March 1998 to February 2008. To find the incidence of cancers, medical records of the subjects were thoroughly reviewed for a follow-up period of one year. The patterns of formal readings of PET and PET/CT were analyzed to assess the sensitivity and specificity for cancer detection. The histopathology and stage of the cancers were evaluated in relation to the results of PET. Results: Eighty-six cancers (1.7%) were diagnosed within one year after PET or PET/CT. When PET and PET/CT results were combined, the sensitivity was 48.8% and specificity was 81.1% for cancer detection. PET only had a sensitivity of 46.2% and a specificity of 81.4%, and PET/CT only had a sensitivity of 75.0% and a specificity of 78.5% respectively. There were no significant differences in cancer site, stage and histopathology between PET positive and PET negative cancers. In 19.3% of formal readings of PET and PET/CT, further evaluation to exclude malignancy or significant disease was recommended. Head and neck area and upper gastrointestinal tract were commonly recommended sites for further evaluation. Conclusions: PET and PET/CT showed moderate performance for detecting cancers in asymptomatic adults in this study. More experience and further investigation are needed to overcome limitations of PET and PET/CT for cancer screening.

The Change of the Knowledge Field in a Transition Period based on the Transition of the Status of Chinese Novels - Focusing Liang Qichao's Assertion, the Revolution of the Novel World (중국소설의 위상 변천으로 본 과도기 지식 장(場)의 변화 - 양계초(梁啓超)의 소설계혁명(小說界革命)을 중심으로 -)

  • Jung, Sun Kyung
    • (The)Study of the Eastern Classic
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    • no.55
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    • pp.115-145
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    • 2014
  • In this paper, the transition of the status of Chinese novels and the change of the knowledge field in the modern times from the end of 19th century to the early 20th century, the transition period between the tradition and the modern times, have been investigated based on Liang Qichao's assertion of the Revolution of the Novel World. How the traditional novels have been evaluated, how modern novels enlightened a people and changed the political society, and what role novels acted in the change of the knowledge field are investigated. Especially I looked into the accumulations of knowledge and changes inside China which were overlooked in the previous researches which focused on the inflow of the Western culture and its impact on Chinese culture. Firstly the evaluation and classification of the traditional novels are considered. Because the transition of the status of novels and the classification method of the catalog of books are tightly coupled with the change of academic ideologies. Later I tried to understand novels as a way of thinking the modern times with a discussion on the changes of modern knowledge society and the consideration of Liang Qichao's Revolution of the Novel World in the two viewpoints, i.e. the relationship between novels and political society, and novels and the style of writing. Liang Qichao raised novels to the topmost position of literature. He pushed the traditional poetry off the top position and replaced it with popular novels. As the outside impact of Western culture made Chinese novels a tool for enlightening the ignorant people and the medium of propagating the knowledge, the status of novels was elevated to the highest level which novels had never reached in the past. With the limitation that the valuation was not based on the aesthetic appreciation of art but based on the value for politics and society, novel was a discourse of life and death to save the country and a container of knowledge to rebuild the people's mind and convert the crisis of the national ruin.

Assessment Research Comparing the Environmental Value of Taebaeksan·NakSan·Kyeongpo Provincial Parks of Kangwon-do (태백산, 낙산, 경포도립공원의 환경가치비교 평가연구)

  • Kang, Kee-Rae;Kim, Dong-Pil;Cho, Woo;Baek, Jae-Bong
    • Korean Journal of Environment and Ecology
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    • v.30 no.2
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    • pp.253-260
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    • 2016
  • This research aimed to quantitatively measure the environmental values of Taebaeksan, Naksan, and Gyeongpo provincial parks located in Gangwon-do. The research was based on the CVM technique which estimates the economic values for all kinds of ecosystem. Also, the estimated value of environment goods can suggest the magnitude of additional utility other than the cost people pay when they visit the provincial parks. Such result can be used as basic data in addition to information on natural ecology or cultural landscape to decide whether the park should be promoted as a national park. The questionnaires-collected from Taebaeksan(180 copies), Naksan(179 copies), and Gyeongpo(180 copies) provincial parks were used to measure the environmental value of each provincial park. Variables that affect the response of 'yes(Y)' or 'no(N)' to the cost suggestion for the economic valuation of environment are estimated under the catagories of environment conservation status (env.), degree of park management (manage.), environmental conservation effort, education (edu.), and income (inc.) of the respondents (execu.), pertaining to the 3 provincial parks in Gangwon-do. The value of natural environment to 1 visitor to the 3 Gangwon provincial parks was estimated by the Logit method that Hanemann proposed using the average of inserted variables. The results showed that the additional environmental value that 1 visitor can gain is 44,060 won for Taebaeksan Provincial Park, 41,191 won for Naksan, and 41,844 won for the Gyeongpo Provincial Park. Taebaeksan Provincial Park's environmental value is estimated at the highest as the respondents judge that its natural environment is well preserved and the facilities are managed well.

A Study on the Replacement of a Light Burnt Dolomite with a Waste MgO-C Refractory Material for a Steel-Making Flux in Electric Arc Furnace (폐 MgO-C계 내화재의 전기로(EAF) 제강 Flux용 경소돌로마이트 대체 사용 연구)

  • Hyun-Jong Kim;Jong-Deok Lim;Hang-Goo Kim;Jei-Pil Wang
    • Resources Recycling
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    • v.31 no.6
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    • pp.44-51
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    • 2022
  • In the steelmaking process using an electric arc furnace (EAF), light-burnt dolomite, which is a flux containing MgO, is used to protect refractory materials and improve desulfurization ability. Furthermore, a recarburizing agent is added to reduce energy consumption via slag foaming and to induce the deoxidation effect. Herein, a waste MgO-C based refractory material was used to achieve the aforementioned effects economically. The waste MgO-C refractory materials contain a significant amount of MgO and graphite components; however, most of these materials are currently discarded instead of being recycled. The mass recycling of waste MgO-C refractory materials would be achievable if their applicability as a flux for steelmaking is proven. Therefore, experiments were performed using a target composition range similar to the commercial EAF slag composition. A pre-melted base slag was prepared by mixing SiO2, Al2O3, and FeO in an alumina crucible and heating at 1450℃ for 1 h or more. Subsequently, a mixed flux #2 (a mixture of light-burnt dolomite, waste MgO-C based refractory material, and limestone) was added to the prepared pre-melted base slag and a melting reaction test was performed. Injecting the pre-melted base slag with the flux facilitates the formation of the target EAF slag. These results were compared with that of mixed flux #1 (a mixture of light-burnt dolomite and limestone), which is a conventional steelmaking flux, and the possibility of replacement was evaluated. To obtain a reliable evaluation, characterization techniques like X-ray diffraction (XRD) analysis and X-ray fluorescence (XRF) spectrometry were used, and slag foam height, slag basicity, and Fe recovery were calculated.

A Comparison Study of Model Reduction Method with Direct Impact Analysis of Truck-column Collision (모델축소법을 이용한 교각-차량 충돌변위 예측 및 직접충돌해석법과의 비교연구)

  • Lee, Jaeha;Kim, Kyeongjin;Jeong, Yoseok;Kim, Wooseok
    • Journal of the Computational Structural Engineering Institute of Korea
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    • v.28 no.6
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    • pp.675-682
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    • 2015
  • Current design codes such as AASHTO LRFD or Korean Highway Bridge Design Code recommend of using static force for designing bridge column against vehicle collisions. However, there was an accident that the bridge was collapsed shortly after vehicle impact on bridge pier in Nebraska(near Big Spring, 2003). It was found that the second largest cause of bridge collapse is collision after hydraulic causes. It can be thought that the possibility of truck-bridge collision are getting increasing as the size of truck increases and traffic condition are becoming improved. However, dynamic behavior under the impact loading seldom considered in bridge design procedure due to computational cost and time. In this study, in order to reduce the computational cost for dynamic impact analysis, model reduction method was developed. Obtained results of residual displacement were compared with the results of direct impact simulations.

DIAGNOSIS OF MICROMETASTASIS IN LYMPH NODE AND CLINICAL EVALUATION OF PROGNOSTIC FACTOR OF ORAL SCC USING RT-PCR AND IMMUNOHISTOCHEMISTRY FOR CYTOKERATIN (Cytokeratin의 RT-PCR 및 면역조직화학적 분석을 이용한 구강편평세포암종의 임파절 미세전이 진단과 예후인자 효용성 평가)

  • Park, Sung-Jin;Lee, Won-Deok;Lim, Ku-Young;Kang, Jin-Han;Myung, Hoon;Lee, Jong-Ho;Kim, Myung-Jin
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.31 no.2
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    • pp.105-115
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    • 2005
  • Purpose: The lymph node status assessed by conventional histological examination is the most important prognostic factor in patients undergoing surgery for oral squamous cell carcinoma. The presence of lymph node metastasis has a strong adverse impact on patient survival even after extended radical resection. Despite these findings, tumour recurrence is not rare after surgery, even when histological examination shows no lymph node metastasis. Recently, molecular-genetically and immunohistochemically demonstrated micrometastasis to the lymph nodes has been shown to have a significant adverse influence on survival in patients with squamous cell carcinoma and histologically negative nodes. The present study sought to determine the incidence and clarify the clinical significance of molecular-genetically and immunohistochemically demonstrated nodal micrometastases and to correlate these data with the stage of oral cancer. Methods: Lymph nodes systematically removed from 71 patients who underwent curative resection between 1998 and 2003 with head and neck squamous cell carcinoma were examined molecular-genetically to detect cytokeratin 5 mRNA with RT-PCR and immunohistochemically to detect cells that stained positively for cytokeratins with the monoclonal antibody cocktail AE1/AE3. The postoperative course and survival rates were compared among patients with and without micrometastases, after numerical classification of overt metastatic nodes. Results: micrometastases were detected in 43(60%) of 71 patients by RT-PCR and 26(36%) of 71 patients by immunohistochemistry. By RT-PCR analysis, patients exhibiting a positive band for CK 5 mRNA had a significantly worse prognosis than those were RT-PCR negative. By immunohistochemistry, the presence of micrometastasis did not predict patient outcome. Conclusion: Micrometastases detected by RT-PCR may be of clinical value in identifying patients who may be at high risk for recurrence and who are therefore likely to benefit from systemic adjuvant therapy.

Development and Effect of a Metabolic Syndrome Prevention Program for University Students using Mobile Application (대학생을 위한 대사증후군 예방교육프로그램 개발 및 효과-어플리케이션(Application) 매체 적용)

  • Kang, Han-Kyu;Kim, Tae-Bin;Kim, Kyu-Hyung;Kim, Min-Jin;Kim, Jin-Hyun;Kim, Hyun-Yong;Yeom, Kyung-Hoon;Lee, Ka-Hyun;Choi, Eun-Young;Kang, Kyung-Ah
    • Child Health Nursing Research
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    • v.20 no.3
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    • pp.205-214
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    • 2014
  • Purpose: The purpose of the study was to develop and evaluate the effect of a metabolic syndrome prevention program using mobile application for university students. Methods: A pretest-posttest design with content analysis as a triangulation method was used. The participants were 49 university students. Data were analyzed using descriptive statistics, $x^2$-test, t-test and Fisher's exact test with the SPSS WIN 18.0 program. Results: The application consisted of six main menus as follows: 'basic education', 'nutrition education', 'exercise education', 'meal diary', 'exercise checkup', and 'tips'. The experimental group had higher recognition about metabolic syndrome prevention than the control group (F=7.919, p=.007). Understanding of metabolic syndrome among participants was mostly related to chronic diseases such as obesity, hypertension and diabetes in relation to the importance of eating habits and exercising. Conclusion: The results indicate that metabolic syndrome prevention education using mobile application is necessary and would be useful for university students.

Effect of delayed time, surface treatment, and repair material on shear bond strength of repaired bis-acryl composite resin (수리된 비스 아크릴 복합 레진의 전단결합강도에 대한 지연시간, 표면처리, 수리 재료의 영향)

  • Park, Ji-su;Lee, Jae-In
    • Journal of Dental Rehabilitation and Applied Science
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    • v.34 no.2
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    • pp.89-96
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    • 2018
  • Purpose: The aim of this study was to evaluate the effect of delayed time, surface treatment, and repair materials on repair of bis-acryl composite resin through comparison of shear bond strength and to evaluate the utility of bis-acryl composite resin repair using polymethyl methacrylate resin. Materials and Methods: A total of 90 bis-acryl composite resin specimens were fabricated and classified into 9 test groups, each of 10 pieces according to delayed time, surface treatment and repair material. The shear bond strength of each specimen was measured using a universal testing machine immediately after fabrication and analyzed using a statistical analysis program (IBM SPSS statistics 20). After the shear bond strength measurement, the fracture surface of the specimen was observed. Results: The highest shear bond strength ($17.54{\pm}3.14MPa$) was observed in the experimental group bonded immediately with a light-curing flowable composite resin using a bonding agent. Conclusion: When repairing bis-acryl composite resin, it is necessary to consider whether to remake according to the delayed time. For effective repair, it is desirable to consider appropriate materials and surface treatment methods according to the site or purpose of use.

Phytoremediation of Soils Contaminated with Heavy Metal by Hosta longipes in Urban Shade (도시 내 음지 중금속 오염지에 대한 비비추의 식물정화 효과)

  • Ju, Jin-Hee;Yoon, Young-Han
    • Journal of Environmental Policy
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    • v.12 no.4
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    • pp.119-132
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    • 2013
  • Hosta longipes is one of the most popular ornamental perennials in use in Korea today, and is mainly used as a groundcover plant in urban shaded places. In this study, the pytoremediation effect of Hosta longipes was tested using four concentrations (Control, 100, 250 and $500mg{\cdot}kg^{-1}$) of Cd, Pb and Zn in soil. The plants were planted in $300mm{\times}200mm{\times}250mm$ drainless-containers, which were filled with a artificial amended soil for 7 months. The results showed that the contents of heavy metals cadmium and lead in the shoot of Hosta longipes increased with increasing heavy metal concentration levels exception of zinc. The amount of zinc, cadmium, and lead accumulated in roots were increased with heavy metal concentration levels up in soil. The shoot/root ratios(TF; translocation factor) values were found to be more than 80% of total Zn, Cd, and Pb take up by Hosta longipes. These results indicated that root is the major part for accumulation of heavy metal. The removal contents of zinc, cadmium, and lead increased significantly with the increasing heavy metal concentration in the soil, which was planted with Hosta longipes. The heavy metal concentration accumulation in plant/soil ratios (BF; bioaccumulation factor) values for three metals were found to be more than 30% in cadmium and lead, but lower in zinc treatments. The different responses of Hosta longipes suggest that in heavy metal contaminated soils the plant adsorbs available metals depending on the concentration soils in which they are present. Therefore, this species can be an efficient phytoremediator for soils contaminated with cadmium and lead in urban shaded places.

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