• Korean Security Journal
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• no.16
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• pp.229-241
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• 2008

he guarding system of the "Choson" era is completed by the Gyeongguk-daejeon(an administrative canon) at the kings "Sejong" and "Yejong", and it is supplemented at the King "Seongjong". "Geum-gun" is composed of "Naegeum-wi", "Gyeombok-sa", "Wirim-wi" and "Jeongro-wi" in the period before the Japanese Aggression of Korea in 1952, and in the period after the aggression war, the organization of the "Geum-gun" is changed repeatedly according to circumstances in the period after the aggression. They("Geum-gun") devote themselves to the protection of kings and the capital defense in the first period of the "Choson" era. The most important change of the "Geum-gun" is the practice of five military units system, three military units of them, "Hunryeon-dogam", "Eoyeong-cheong" and "Geumwi-yeong", take charge of the guard of kings and the capital defense, and "Chongyung-cheong" and "Sueo-cheong" take charge of the defense of the outer areas of the capital region with key positions located at "Namhan-sanseong" and "Bukhan-sanseong"(mountain fortress Walls). The function of the "Geum-gun" is extended through the aggressions, therefore the number of soldiers is increased greatly. The guarding system for the country and its royal family is frequently changed according to the improvement of the people's position with themselves-awakening and their understanding of realities. The reorganization of the "Geum-gun" including "Howi-cheong", "Geumgun-cheong", "Sukwi-so" and "Jangyong-yeong" is unavoidable to strengthen the royal rights that are weaken by deposing the king "Injo". The standing of the existing organizations is changed many times with financial problems. The enthronement of the king "Jeongjo" is a great epoch in the change of the guarding system.

• Journal of Chest Surgery
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• v.39 no.4 s.261
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• pp.298-303
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• 2006

Background: This study was performed to investigate the outcomes of vascular operations that were done in patients with atheroscerosis obliterans (ASO) of lower limb. Material and Method: Forty patients underwent vascular operations from December 1996 to June 2004. The patient's records were analyzed retrospectively. Mean age was $66{\pm}8$ years (range, $47{\sim}81$ years). Gender ratio was 37:3 (male:female). Result: The operations were done on 50 lower limbs of 40 patients. The names of operations were femoropopliteal bypass in 12 patients (30%), femorofemoral bypass in 12 (30%), femorofemoral bypass and femoropopliteal bypass in five (12.5%), aorta-lower limb artery bypass in five (12.5%), axillofemoral bypass in two (5%), iliopopliteal bypass in two (5%), and endarterectomy in two (5%). All bypass surgeries were done with prosthetic conduits. Mean follow up period was $33.2{\pm}23.2$ months (range, $3.8{\sim}90.2$ months). The cumulative patency rates of 1 and 5 years were 75.5 and 58.7% respectively. In six patients, amputation of the lower limb was done. In eight patients, 12 complications occurred. After the first operation, 10 patients underwent reoperations. Conclusion: Our lower limb arterial bypass surgery revealed acceptable patency rate, but not a few patients required reoperations. An epochal treatment modality that can inhibit the progress of ASO and improve long term patency should be established.

• Journal of Korean Society of Transportation
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• v.27 no.5
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• pp.97-111
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• 2009

Image-based traffic information collection systems have entered widespread adoption and use in many countries since these systems are not only capable of replacing existing loop-based detectors which have limitations in management and administration, but are also capable of providing and managing a wide variety of traffic related information. In addition, these systems are expanding rapidly in terms of purpose and scope of use. Currently, the utilization of image processing technology in the field of traffic accident management is limited to installing surveillance cameras on locations where traffic accidents are expected to occur and digitalizing of recorded data. Accurately recording the sequence of situations around a traffic accident in a signal intersection and then objectively and clearly analyzing how such accident occurred is more urgent and important than anything else in resolving a traffic accident. Therefore, in this research, we intend to present a technology capable of overcoming problems in which advanced existing technologies exhibited limitations in handling real-time due to large data capacity such as object separation of vehicles and tracking, which pose difficulties due to environmental diversities and changes at a signal intersection with complex traffic situations, as pointed out by many past researches while presenting and implementing an active and environmentally adaptive methodology capable of effectively reducing false detection situations which frequently occur even with the Gaussian complex model analytical method which has been considered the best among well-known environmental obstacle reduction methods. To prove that the technology developed by this research has performance advantage over existing automatic traffic accident recording systems, a test was performed by entering image data from an actually operating crossroad online in real-time. The test results were compared with the performance of other existing technologies.

• (The)Study of the Eastern Classic
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• no.48
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• pp.41-63
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• 2012

This research paper is aims to study the Zhu Xi school of Neo-Confucianism culture based on the Sosu seowon. Also This research paper is to discuss study and scholars correlation the Sosu seowon. The Sosu seowon is mainly made up of the Zhu Xi school of Neo-Confucianism development. The Sosu seowon was the cradle of scholars and bureaucrats. Scholars who study of orthodox Neo-Confucianism in the our country was respected academic spirit of An Whyang in the study of orthodox Neo-Confucianism. An Whyang is symbolic existence of the Sosu seowon. He knew well the importance of learning. He was the person to represent the Sosu seowon. Toegye and Sinje are handed down to the fundamental principle brought in on the orthodox Neo-Confucianism caused by An Whyang. This research paper is to based upon on academic spirit of An Whyang in the study of orthodox Neo-Confucianism. Scholars who study of orthodox Neo-Confucianism thought that the nation's happiness made appointment to a competent person learned the orthodox Neo-Confucianism caused by An Whyang related to the Humanism education.

• Cross-Cultural Studies
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• v.40
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• pp.239-264
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• 2015

In the early 20th century, Japan built theaters to take possession of colonial culture while establishing the Imperial University, libraries, and museums to accumulate and spread the knowledge of "imperial" Japan. Many different genres made a hit in theaters including theatrical troupes, theatrical companies, and motion pictures. One of the various features of expositions was "spectacles" or unusual events. They were integrated with a national festival in celebration of "5th anniversary of political commencement." In 1915, the longest hit series in Keijo (Seoul) was the dance performance by professional Japanese beauties and entertainers, whose songs delivered the legitimacy of governance. This study focused on the performance in the space of "cultural" spread called theaters, thus examining the "imperial" cultural waves they were in charge of. The study also focused on the tensional relations of Hierarchie along those cultural borders. The performance at the theater Engeikan(演芸館) in 1915 was especially an epoch-making event in the Japanese theatrical community of Keijo (Seoul): first, it marked the emergence of large-scale performance hall called Engeikan(演芸館); secondly, the performance kept its ongoing, stable streak for about 50 days; and it led to the appearance of leading troupes including Geijutuza(芸術座), which put on a show in Keijo (Seoul) in November, 1915. The study examined the issues of theater Engeikan(演芸館) performance in 1915 involving the art company, performance genre, and audience composition, showed that there was the coexistence of entertainment and governance through cultural ruling while securing amusement and entertainment, and found it was accompanied by the organized operation of "Keijo Sponsorship Council（京城協贊會）" which brought together the cultural capabilities of Japanese people living in Joseon. The performance at theater Engeikan(演芸館) in Keijo (Seoul) in 1915 fully reflected the issues involving the tensional relations between different artistic genres, the competing relations between the subjects of performance, and the cultural power.

• Proceedings of the Korea Water Resources Association Conference
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• 2015.05a
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• pp.648-648
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• 2015

이 연구는 수자원 환경을 전반적으로 객관화, 계량화하는 새로운 방법이 성공적임을 소개한다. 기존의 계량법이 일강수량, 월 강수량, 년 강수량 등등, 단순한 수학적 합계에 치중한 결과 가중 중요한 강수의 시간 분포를 간과하였다. 이 단점을 해결하여, 1) 구체적으로 매 시간, 매일 남아 있다고 추정되는 물의 양 만을 합산하는 방법을 택했다. 시간적 감소함수를 이용하여, 강수 후 유출과 증발 등으로 사라지는 물의 양을 고려한 것이다. 2) 합산기간을 객관화하였다. 기본 합산 기간을 365일로 하고, 물 부족 또는 물 과잉이 지속될 경우는 지속되는 기간만큼, 합산기간을 늘이는 방법을 택했다. 따라서 다른 지수들이 임의로 3개월 또는 12개월 등등으로 기간을 결정하는 단점을 해결했다. 이렇게 계산되는 4차원 강수지수(4-Dimensional Rain Index, 4RI)는 1) 일별유효강수지수 (AWRI), 2) 일별가뭄지수(EDI), 3) 일별 홍수지수(FI), 4) 시간별 장기 물지수(LWI), 5) 시간별 단기 물지수(SWI) 등 5개가 기본지수이다. AWRI는 매일 남아 있는 물의 양이다. 이로 인해, 전 지구의 수자원과 재해위험의 시공간적 분포의 정량화 분석이 정밀해졌다. 지구상에서 물 집중이 가장 강한 곳은 캄보디아 내의 한 지점이며 시기는 7월 말이고, 가장 약한 곳은 사하라 사막의 한 지역임이 확인되었다. 또 한국에서 발생하는 갈수기와 풍수기가 정의되었고, 이들의 각 지역별 특성과 차이가 정량적으로 드러났다. 시간적 분포 또한 명확하게 드러나, 각종 저수지의 물 관리나 농?임산물의 생산관리에 획기적 전환점이 마련되었다. 각 국가별로, 각 지역별로 이런 분석은 향후도 무수히 시도되어야 할 것이다. EDI는 매일의 AWRI를 그 날짜의 평균치와 비교한 값이다. 장기가뭄 및 단기가뭄의 강도를 모두 가장 정밀하게 표현한다. FI는 일별로 홍수, 산사태, 침수, 토사 (이하 홍수 등이라 칭함)의 위험을, LWI는 장기 누적된 강수량에 의한 돌발적 홍수 등의 위험을, SWI는 단기 누적된 강수량에 의한 돌발적 홍수 등의 위험을 잘 반영한다. 이들은 모두 시간적으로 산발적인 호우에 의한 홍수 등의 위험을 한 개의 지수로 표현해 주는 장점이 있다. 강수 후 홍수가 발생하기 까지는 시간차이가 있기 때문에, 특히 호우 경보에는 SWI가, 홍수 경보에는 LWI가 아주 효과적이다. 결론적으로 5개의 4차원 강수지수는 물환경의 시공간적 분포진단과 예측, 그리고 조기경보에 혁명적 진화를 초래함이 확인되었다. 따라서 추후 모든 강수기후와 연관된 연구는 연강수량 등의 단순 합산보다, 4차원 강수지수를 먼저 사용하는 것이 바람직 할 것임이 제안되었다.

• Korean Journal of Clinical Laboratory Science
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• v.53 no.4
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• pp.309-316
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• 2021

Sepsis is a physiological response to a source of infection that triggers mechanisms that compromise organ function, leading to death if not treated early. Biomarkers with high sensitivity, specificity, speed, and accuracy that could differentiate sepsis from non-infectious systemic inflammatory response syndrome (SIRS) could bring about a revolution in sepsis treatment. Given the limitations and time required for microbial verification of pathogens, the accurate diagnosis of infection before employing antibiotic therapy is important and clinically necessary. Procalcitonin (PCT), lactate, C-reactive protein (CRP), cytokines, and proadrenomedullin (ProADM) are the common biomarkers used for diagnosis. The procalcitonin (PCT)-guided antibiotic treatment in patients with acute respiratory infections effectively reduces antibiotic exposure and side effects while improving survival rates. The evidence regarding sepsis screening in hospitalized patients is limited. Clinicians, researchers, and healthcare decision-makers should consider these findings and limitations when implementing screening tools, future research, or policy on sepsis recognition in hospitalized patients. The use of biomarkers in pediatric sepsis is promising, although such use should always be correlated with clinical evaluation. Biomarkers may also improve the prediction of mortality, especially in the early phase of sepsis, when the levels of certain pro-inflammatory cytokines and proteins are elevated.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.19 no.11
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• pp.744-749
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• 2018

Informatization and visualization technology for real space is a key technology for construction of geospatial information. Three-dimensional (3D) modeling is a method of constructing geospatial information from data measured by various methods. The 3D laser scanner has been mainly used as a method for acquiring digital elevation data. On the other hand, the unmanned aerial vehicle (UAV), which has been attracting attention as a promising technology of the fourth industrial revolution, has been evaluated as a technology for obtaining fast geospatial information, and various studies are being carried out. However, there is a lack of evaluation on the quantitative work efficiency and data accuracy of the data construction technology for 3D geospatial modeling. In this study, various analyses were carried out on the characteristics, work processes, and accuracy of point cloud data acquired by a 3D laser scanner and an unmanned aerial vehicle. The 3D laser scanner and UAV were used to generate digital elevation data of the study area, and the characteristics were analyzed. Through evaluation of the accuracy, it was confirmed that digital elevation data from a 3D laser scanner and UAV show accuracy within a 10 cm maximum, and it is suggested that it can be used for spatial information construction. In the future, collecting 3D elevation data from a 3D laser scanner and UAV is expected to be utilized as an efficient geospatial information-construction method.

• Korean Chemical Engineering Research
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• v.57 no.4
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• pp.445-454
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• 2019

Layered double hydroxides (LDHs) nanoparticles have emerged as novel nanomaterials for bio-imaging applications due to its unique layered structure, physicochemical properties, and good biocompatibility. Bio-imaging is one of the most important fields for medical applications in clinical diagnostics and therapeutics of various diseases. Enhanced diagnostic techniques are needed to realize new paradigm for next-generation personalized medicine through nanoscale materials. When nanotechnology is introduced into bio-imaging system, nanoparticle probes can endow imaging techniques with enhanced ability to obtain information about biological system at the molecular level. In this review, we summarize structural features of LDH nanoparticles with current issues of bio-imaging system. LDH nanoparticle probes are also discussed through in vitro as well as in vivo studies in various bio-imaging techniques including fluorescence imaging, magnetic resonance imaging (MRI), positron emission tomography (PET), and computed X-ray tomography (CT), which will have the potential in the development of the advanced nanoparticles with high sensitivity and selectivity.

• Journal of Life Science
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• v.29 no.7
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• pp.824-835
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• 2019

In recent decades, oncolytic viruses (OVs) have extensively been investigated as a potential cancer drug. Oncolytic viruses have primarily the unique advantage in the fact that they can only infect and destroy cancer cells. Secondary, oncolytic viruses induce the activation of specific adaptive immunity which targets tumor-associated antigens that were hidden during the initial cancer progression. In 2015, one genetically modified oncolytic virus, talimogene laherparepvec (T-VEC), was approved by the American Food and Drug Administration (FDA) for the treatment of melanoma. Currently, various oncolytic viruses are being investigated in clinical trials as monotherapy or in combination with preexistent cancer therapies like immunotherapy, radiotherapy or chemotherapy. The efficacy of oncolytic virotherapy relies on the balance between the induced anti-tumor immunity and the anti-viral response. Despite the revolutionary outcome, the development of oncolytic viruses for the treatment of cancer faces a number of obstacles such as delivery method, neutralizing antibodies and induction of antiviral immunity due to the complexity, variability and reactivity of tumors. Intratumoral administration has been successful reducing considerably solid tumors with no notable side effects unfortunately some tumors are not accessible (brain) and require a systemic administration of the oncolytic viruses. In order to overcome these hurdles, various strategies to enhance the efficacy of oncolytic viruses have been developed which include the insertion of transgenes or combination with immune-modulatory substances.