• Title/Summary/Keyword: 회복률

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An estimation method of probability of infection using Reed - Frost model (Reed - Frost 모형을 이용한 전염병 감염 확률 추정)

  • Eom, Eunjin;Hwang, Jinseub;Choi, Boseung
    • Journal of the Korean Data and Information Science Society
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    • v.28 no.1
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    • pp.57-66
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    • 2017
  • SIR model (Kermack and McKendrik, 1927) is one of the most popular method to explain the spread of disease, In order to construct SIR model, we need to estimate transition rate parameter and recovery rate parameter. If we don't have any information of the two rate parameters, we should estimate using observed whole trajectory of pandemic of disease. Thus, with restricted observed data, we can't estimate rate parameters. In this research, we introduced Reed-Frost model (Andersson and Britton, 2000) to calculate the probability of infection in the early stage of pandemic with the restriction of data. When we have an initial number of susceptible and infected, and a final number of infected, we can apply Reed - Frost model and we can get the probability of infection. We applied the Reed - Frost model to the Vibrio cholerae pandemic data from Republic of the Cameroon and calculated the probability of infection at the early stage. We also construct SIR model using the result of Reed - Frost model.

A study of epidemic model using SEIR model (SEIR 모형을 이용한 전염병 모형 예측 연구)

  • Do, Mijin;Kim, Jongtae;Choi, Boseung
    • Journal of the Korean Data and Information Science Society
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    • v.28 no.2
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    • pp.297-307
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    • 2017
  • The epidemic model is used to model the spread of disease and to control the disease. In this research, we utilize SEIR model which is one of applications the SIR model that incorporates Exposed step to the model. The SEIR model assumes that a people in the susceptible contacted infected moves to the exposed period. After staying in the period, the infectee tends to sequentially proceed to the status of infected, recovered, and removed. This type of infection can be used for research in cases where there is a latency period after infectious disease. In this research, we collected respiratory infectious disease data for the Middle East Respiratory Syndrome Coronavirus (MERSCoV). Assuming that the spread of disease follows a stochastic process rather than a deterministic one, we utilized the Poisson process for the variation of infection and applied epidemic model to the stochastic chemical reaction model. Using observed pandemic data, we estimated three parameters in the SIER model; exposed rate, transmission rate, and recovery rate. After estimating the model, we applied the fitted model to the explanation of spread disease. Additionally, we include a process for generating the Exposed trajectory during the model estimation process due to the lack of the information of exact trajectory of Exposed.

Analysis of runoff by change of impervious surface ratio in Anseong-cheon (안성천 유역의 불투수면적률 변화에 따른 유출량 분석)

  • Lee, Hyunji;Kang, Moon Seong;Kim, Kyeung;Kim, Ji Hye;Kim, Seok Hyeon
    • Proceedings of the Korea Water Resources Association Conference
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    • 2019.05a
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    • pp.358-358
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    • 2019
  • 도시화 및 산업화로 인해 불투수면이 지속적으로 증가하고 있으며, 불투수면의 증가로 인해 물순환 구조 왜곡이 발생하고 있으며, 이로 인해 집중 호우시 첨두유량 증가로 인한 도시 침수, 자연적 침투량 감소로 인한 지하수 고갈 및 하천 건천화, 도시 열섬 현상 등 다양한 물 문제가 발생하고 있다. 건강한 물순환 체계 회복을 위해, 환경부에서는 소권역별 불투수면적률에 대한 중장기 물순환 목표를 포함하여 물환경보전법을 개정하였으며, 2020년부터 시행예정이다. 본 연구에서는 안성천 유역을 대상으로 소권역별 불투수면적률을 산정하고 불투수면적률 저감에 따른 유출량 등의 유역 물순환 구조 변화를 분석하고자 한다. 불투수면적률은 연속수치지도, 연속지적도, 용도지역 지구도 3개의 지리정보자료를 중첩하여 최신 불투수면적 정보가 반영되도록 계산하였으며, 물순환 구조는 HSPF 모형을 이용하여 분석하였다. 본 연구의 결과는 향후 불투수면적과 물순환 요소간의 상관관계 분석을 위한 기초자료로 활용될 수 있을 것으로 사료된다.

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Dimensional Stabilization through Heat Treatment of Thermally Compressed Wood of Korean Pine (잣나무 열압밀화재의 열처리를 통한 치수안정화)

  • Lee, Jeong Min;Lee, Won Hee
    • Journal of the Korean Wood Science and Technology
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    • v.46 no.5
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    • pp.471-485
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    • 2018
  • Post-heat treatment experiments were carried out for complete dimensional stabilization of thermally compressed wood (Pinus koraiensis). An absorption test was carried out to evaluate the dimensional stability. The specific gravity increased from 0.43 to 0.79 by thermal compression at a compression ratio of 50% thickness. Through the post-heat treatment of compressed wood, the water absorption and thickness swelling decreased with increasing the heat treatment temperature and time. In the case of the thickness recovery rate, when the heat treatment was performed for 24 hours at $120^{\circ}C$, $140^{\circ}C$ and $160^{\circ}C$, the thickness recovery was less than 1%. Therefore, it can be confirmed that the method of dimensional stabilization method of the thermal compression wood can be carried out very effectively through post heat treatment process.

Decrease of Genotoxicity by Red Ginseng Root Extract (I) - Decrease of UV -induced Genotoxicity by Red Ginseng Root Extract in Cultured NIH3T3 Cells (홍삼 추출물에 의한 유전독성 감소효과 (I) - 배양 NIH3T3 세포에서 자외선에 의한 유전독성의 감소에 미치는 홍삼추출물 처리효과)

  • 김완주;유병수
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.24 no.1
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    • pp.74-86
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    • 1998
  • We have studied the effects of red ginseng root extract on the decrease of UV-induced genotoxicity in cultured NIH3T3 cells. The increase in survival and the recovery from DNA synthesis inhibition in UV-irradiated cells as a function of normal medium incubation time was potentiated by the presence of the ginseng extract. The extract also increased the UV-induced excision repair as determined by unscheduled DNA synthesis. The amount of UV-induced DNA single strand breaks that are accumulated by polymerase inhibitors was significantly increased by the presence of the extract. These results suggest that the red ginseng extract activates the incision/excision step of UV-induced repair and could be used as a reagent for protecting UV-induced genotoxicity and cytotoxicity.

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Applicability evaluation of GIS-based erosion models for post-fire small watershed in the wildland-urban interface (WUI 산불 소유역에 대한 GIS 기반 침식모형의 적용성 평가)

  • Shin, Seung Sook;Ahn, Seunghyo;Song, Jinuk;Chae, Guk Seok;Park, Sang Deog
    • Journal of Korea Water Resources Association
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    • v.57 no.6
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    • pp.421-435
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    • 2024
  • In April 2023, a wildfire broke out in Gangneung located in the east coast region due to the influence of the Yanggang-local wind. In this study, GIS-based RUSLE(Revised Universal Soil Loss Equation) and SEMMA (Soil Erosion Model for Mountain Areas) were used to evaluate the erosion rate due to vegetation recovery in a small watershed of the Gangneung WUI(Wildland-Urban Interface) fire. The small watershed of WUI fire has a low altitude range of 10-30 m and the average slope of 10.0±7.4° which corresponds to a gentle slope. The soil texture was loamy sand with a high organic content and the deep soil depth. As herbaceous layer regenerated profusely in the gully after the wildfire, the NDVI (Normalized Difference Vegetation Index) reached a maximum of 0.55. Simulation results of erosion rates showed that RUSLE ranged from 0.07-94.9 t/ha/storm and SEMMA ranged from 0.24-83.6 t/ha/storm. RUSLE overestimated the average erosion rate by 1.19-1.48 times compared to SEMMA. The erosion rates were estimated to be high in the middle slope where burned pine trees were widely distributed and the slope was steep and to be relatively low in the hollow below the gully where herbaceous layer recovers rapidly. SEMMA showed a rapid increase in erosion sensitivity under at certain vegetation covers with NDVI below 0.25 (Ic = 0.35) on post-fire hillslopes. Gentle slopes with high organic content and rapid recovery of natural vegetation had relatively low erosion rate compared to steep slopes. As subsequent infrastructure and human damages due to sediment disaster by heavy rain is anticipated in WUI fire areas, the research results may be used as basic data for targeted management and decision making on the implementation of emergency treatment after the wildfire.

Recovery from the Two-generation Reproductive Toxicity in Sprague-Dawley Rats by Treatment with Decursin and Decursinol Angelate (Decursin and decursinol angelate가 2세대 출산률 회복에 미치는 영향)

  • Kim, Kang Min;Ok, Seon;Go, Youn Suk;Kang, Jae Seon
    • Journal of Life Science
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    • v.25 no.7
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    • pp.765-772
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    • 2015
  • The aim of this study was to determine the effect of decursin (D) and decursinol angelate (DA) against bisphenol A (BPA) toxicity in a rat two-generation study. Adult rats were divided into the following three groups: (1) control, (2) BPA, and (3) BPA+D/DA. The D and DA treatment of F0 parents increased the terminal body weight and relative adult organ weights (testes, kidneys, spleen, and liver) when compared with the BPA group. A significant decrease in sperm count was found in the BPA+D/DA (7.69%) and BPA (64.70%, p<0.01) groups, when compared with the sperm count in the control group. No offspring were obtained in the F1 generation of the BPA (50 mg/kg/day) group, but the addition of D/DA in the BPA+D/DA group significantly restored fertility (55.78%) and gestation indices (98.87%) in the F1 generation. No significant differences were found in the fertility index between the control (75.02%) and the BPA+D/DA (78.11%) groups in the two-generation study, when compared with the one-generation study. The viability ratio during lactation in the D/DA group was also similar to that of the control group. These data indicate that D/DA (50 mg/kg/day) administered over two generations causes significant positive changes in reproductive or developmental parameters.

Outcomes of the Modified Maze Procedure for Chronic Atrial Fibrillation Combined with Rheumatic Mitral Valve Disease (류마티스성 승모판막질환과 동반된 만성 심방세동 치료에 대한 변형 Maze 술식의 결과)

  • Baek Man-Jong;Kim Jae-Hyun;Seo Hong-Joo;Lee Chang-Ha;Oh Sam-Se;Na Chan-Young
    • Journal of Chest Surgery
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    • v.39 no.9 s.266
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    • pp.681-691
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    • 2006
  • Background: The aim of this study was to investigate the mid-term outcomes of our modifications to the maze procedure using cryoablation for treating atrial fibrillation associated with rheumatic mitral valve disease. Material and Method: Between March 2000 and February 2004, 177 consecutive patients underwent the modified maze procedure with the use of cryoablation concomitant with mitral valve surgery for atrial fibrillation associated with rheumatic mitral valve disease, and were divided into three groups: (1) modified Cox-maze III (CM group, n=88): (2) modified Kosakai-maze (KM group, n=63): and (3) left atrial maze procedure (LA group, n=26). The postoperative and follow-up results were analyzed and compared between the groups. Result: There were three hospital deaths (1.7%) and no significant differences in the incidence of postoperative complications between the three groups. The operative time, such as the cardiopulmonary bypass and aortic crossclamp time, were significantly longer in the CM group than in the KM and LA groups, respectively (p<0.0001). The mean follow-up was $22.4{\pm}15.1$ months ($1\sim52.6$ months) for all patients. One late death developed in the CM group (0.0%). At last follow-up, 139 patients exhibited sinus rhythm (79.9%), which was also regained in 67 patients (77.9%) in the CM group, 50 (80.7%) in the KM group and 22 (84.6%) in the LA group (p=0.743). The actuarial freedom from stroke at 4 years was $84.5{\pm}9.4%$ in the CM group, $95.0{\pm}4.9%$ in the KM group, and $92.9{\pm}6.9%$ in the LA group (p=0.916). Conclusion: The modified maze procedure using cryoablation is safe and effective in treating chronic atrial fibrillation associated with rheumatic mitral valve disease.

해운이슈 - Seri, 2013 국제유가의 향방 발표

  • 한국선주협회
    • 해운
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    • s.95
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    • pp.17-25
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    • 2012
  • 세계경제 둔화에도 국제유가가 상승세로 전환되었다. 국제유가는 2012년 1/4분기에 이란 사태로 인해 급등했다가 2012년 2/4분기에는 유로존 위기 등으로 급락했던 국제유가가 하반기에 들어 상승세로 전환되었다. 그러나 세계경제의 부진이 지속되면서 실물수요 측면의 유가 상승압력은 낮은 수준을 유지한다. IMF 등 주요 기관은 유로존 위기 등으로 세계경제의 회복세가 약화되자 2012년과 2013년 세계경제의 성장률을 하향 조정했다. 특히, 금융위기 발생 이후 세계경제의 버팀목이 되던 신흥국 경제의 성장 둔화가 본격화 되면서 석유 등 실물 수요도 둔화되었다. 2012년 3/4분기 중국의 성장률은 7.4%로 7분기 연속 하락했으며, IMF와 Global Insight는 2012년 중구그이 경제성장률을 각각 7.8%, 7.4%로 전망했다. 다음은 삼성경제연구소가 발표한 "2013 국제유가의 향방"의 주요 내용을 요약 정리한 것이다.

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Chinese Hamster Ovary세포에서 Benzo(a)pyrene과 3-Methylcholanthrene에 의한 DNA 단사절단과 복제억제에 미치는 Saponin의 영향

  • 이정섭;이형호;박기현;박상대
    • Environmental Mutagens and Carcinogens
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    • v.10 no.2
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    • pp.127-134
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    • 1990
  • 본 연구는 Chinese hamster ovary (CHO-KI) 배양세포에서 S-15분획에 의해 활성화된 bezo(a) pyrene (BP)과 3-methylcholanthrene(MC)에 의해 유발된 DNA단사절단과 DNA복제억제 및 그 회복과정에 미치는 한국산 인삼추출물 saponin의 영향을 조사하여 다음과 같은 결과를 얻었다. S-15분획으로 활성화된 10-5 M의 BP 또는 MC를 1.0-10ng/ml의 saponin과 함께 처리할 경우 BP와 MC단독처리군에 비해 DNA 단사절단률이 감소하였다. DNA 합성률은 활성화된 10-5M의 BP와 10-6 M의 MC에 의해 각각 50% 및 75% 억제되었으나, 0.1-10ng/ml의 saponin을 동시에 처리할 경우 DNA 합성억제률이 약 10% 이상 둔화되었다.

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