• Title/Summary/Keyword: 활성소재

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Cosmetic Effects of Dietary Fiber from Mozuku, Cladosiphon novae-caledoniae Kylin (큰실말(Cladosiphon novae-caledoniae Kylin) 부산물의 화장품소재 특성)

  • Kim, In Hae;Lee, Jae Hwa
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.42 no.3
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    • pp.285-295
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    • 2016
  • To investigate the effect of dietary fiber from mozuku, Cladosiphon novae-caledoniae kylin (C. novae-caledoniae kylin) on the skin care, we measured anti-oxidant activity, anti-microbial activities, tyrosinase activity inhibition and elastic activity. B16F10 melanoma cell (MTT assay) were used to measure cell viability. MC and MI exhibited in vitro antibacterial activity against Staphyloccus aureus (S. aureus) and MRSA without antifungal activity. Mozuku extract (MS) showed excellent tyrosinase inhibition effect compared to arbutin as a positive control (to 49% for tyrosine). The wrinkle-improving effect was relatively low. However, wrinkle-improving effect was relatively low. DPPH free radical scavenging activity was 89% in a concentrations at $500{\mu}g/mL$. These results indicate that the mozuku extracts may be an effective cosmetic ingredient for skin whitening.

A Study on the Effectiveness of In Vitro as a Cosmetic Material of Sericin Originated from Silkworm Kochi (누에고치에서 유래된 세리신(Sericin)의 화장품 소재로서 In Vitro 효능 연구)

  • Hyun-Ji Kwon;Jihye Lee;Eun-mi Jung;Eunhong Lee;Jinhan Park;Sung-Eum Oh;Sanghyeok Park;Ji Wook Jung
    • Journal of the Korean Applied Science and Technology
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    • v.40 no.1
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    • pp.88-94
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    • 2023
  • Sericin is a protein extracted from the cocoon and has many health benefits. This study was conducted to evaluate the anti-wrinkle and anti-inflammatory activity of sericin derived from cocoon as a cosmetic material. The antioxidant activity of sericin was measured by DPPH and ABTS assays. In addition, cell viability was confirmed in Raw 264.7 cells, which are macrophages, and the anti-inflammatory effect of sericin was investigated using the inflammatory response induced using lipopolysaccharide (LPS). It shows that sericin has antioxidant activity and can be an excellent material for anti-aging and anti-inflammatory cosmetics.

Verification of Antioxidant Activity from Velvet Bean (Mucuna pruriens) Extracts (벨벳콩(Mucuna pruriens) 추출물의 항산화 효능 검증)

  • Nam-Yoan Park;Dong-Geun Han;GE-GE;Min-Jun Bae;Hyun-Jeong Kim;Se-Gie Kim;Eun-Young Choi;Bong-Jeon An
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.49 no.1
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    • pp.9-16
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    • 2023
  • In this study, we tried to verify the value of the use of Mucuna pruriens (M. pruriens) extract as an antioxidant functional cosmetic material based on natural materials. After extracting, concentrating, and freeze-drying M. pruriens with water, 70% ethanol, and 70% acetone as solvents, samples of powdered hydrothermal extract (MW), 70% ethanol extract (ME), and 70% acetone extract (MA) were prepared. As a result of analyzing antioxidant activity through DPPH radical scavenging activity, ABTS+ radical scavenging activity, SOD-like activity, reduction ability, total phenol and flavonoid content analysis using MW, ME, and MA, all showed excellent antioxidant effects. Therefore, it is believed that M. pruriens extract is highly likely to be used as a natural material for antioxidant-related functional cosmetics.

Comparison of Anti-Oxidant Activities of Chaff Vinegar Liquor (왕겨초액의 산화억제 활성 비교)

  • Nam, Dong-Yoon;Lee, Si-Rim;Park, Chul-Hong;Park, Kyu-Sik;Nam, Sang-Heon;Heo, Jin-Chul;Lee, Sang-Han
    • Food Science and Preservation
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    • v.17 no.3
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    • pp.430-434
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    • 2010
  • This study was carried out to compare anti-oxidant activities of chaff vinegar liquors. We examined the effects of several kinds of chaff vinegar liquor (CA; CA1, chaff vinegar liquor; CA2, wood vinegar liquor; CA3, chaff vinegar liquor with red ginseng; and CA4, chaff vinegar liquor with rosemary) by 1,1-diphenyl-2-picrylhydrazyl (DPPH), ferric reducing activity of plasma (FRAP) assay, and $Cu^{2+}$ reduction. The results showed that CA have potential in reducing DPPH, FRAP and $Cu^{2+}$ activity. CA was increased its anti-oxidant activity by the fermentation of rosemary extract. The present results suggest that the chaff vinegar liquor could be used for anti-oxidant agents and/or be developed for anti-oxidative potentiation of prototypes.

Anti-wrinkle Activities Verification of Buplerum falcatum Extracts on CCD-986sk (CCD-986sk세포내 시호 추출물의 항주름 활성 검증)

  • Kim, Dong-Hee;Park, Tae-Soon;Son, Jun-Ho
    • Journal of Applied Biological Chemistry
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    • v.58 no.2
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    • pp.183-187
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    • 2015
  • The electron donating ability, elastase inhibitory, procollagen synthesis and Matrix metalloprotease-1 (MMP-1) activities were measured in order to verify the anti-wrinkle properties of extracts from Buplerum falcatum as a functional ingredient for cosmetic products. Electron donating ability and elastase inhibition activities were 80 and 52% at a dose of $1,000{\mu}g/mL$ of B. falcatum 70% ethanol extract. Pro-collagen synthesis was increased with the increase concentration of B. falcatum extract on CCD-986sk in addition to decrease the amount of protein of MMP-1. The results suggested that B. falcatum extract can be used to reduced electron donating ability, elastase, pro-collagen synthesis and MMP-1 activity and is a potential candidate for cosmedical materials.

Effect on Wnt/β-catenin Pathway of Methanol Extracts from Native Plants in Korea (국내자생식물 메탄올추출물의 Wnt/β-catenin 신호전달체계에 대한 효과)

  • Kim, Bora;Kim, Hyun-Soo
    • Korean Journal of Plant Resources
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    • v.29 no.5
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    • pp.620-624
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    • 2016
  • The Wnt/β-catenin signaling pathway is mandatory in adipogenesis. In this study, we investigated the applicability of functional materials for the treatment of obesity by examining Wnt/β-catenin pathway reporter activity related to adipocyte differentiation inhibiting with korean native plant extracts. The luciferase activity of HEK 293-TOP cells increased the reporter activity approximately 152% and 130% by treatment with Sanguisorba officinalis and Thuja orientalis, respectively. Ricinus communis were represented about 90% higher activity, two samples(Rosa rugosa and Sophorae Flos) showed 80% higher activity than the control. Three samples of plant extracts (Zanthoxylum piperitum, Pueraria thunbergiana, Solanum nigrum) were about 70% higher activity compared with the non-treated control. Cytotoxicity of plant extracts was not detected in the rat neural stem cells. These results suggest that the selected eight plant extracts are safe compounds. Our findings indicate that Wnt/β-catenin pathway reporter activity could be used for high throughput screening system. In addition, the plant extracts selected as candidates for adipocyte differentiation inhibiting may be potential therapeutic agents for obesity, it will be exploring the possibility of developing an anti-obesity materials through further experiments with selected plant extracts.

Verification of anti-oxidative activity of Aruncus dioicus, a native plant of Ulleungdo (울릉도 자생식물 삼나물(Aruncusdioicus)의 항산화 활성 검증)

  • Kim, Dong-Hee;Moon, Yong-Sun;Son, Jun-Ho
    • Journal of Plant Biotechnology
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    • v.42 no.1
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    • pp.55-59
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    • 2015
  • The extracts of Aruncus dioicus were investigated for anti-oxidant and biological activities in order to verify its potential as functional ingredients of cosmetic products. The ethyl acetate (EtOAc) extract of A. dioicus showed excellent scavenging activity using DPPH and ABTS anti-oxidant analysis at the $1,000{\mu}g/mL$ concentration. While tyrosinase inhibitory effect was measure for whitening assay and showed 59.2%, the suppression levels of elastase and collagenase were 56% and 90% respectively for anti-wrinkle activity. Therefore, it is plausible to conclude that A. dioicus extract, especially EtOAc fraction which has outstanding whitening, anti-oxidant, and anti-wrinkle activities, could be used as a new functional materials for cosmetics.

Anticariogenic Activities of Various Plant Extracts (항충치효과를 가진 식물 소재 탐색)

  • Choi, In-Wook;Jung, Chang-Hwa;Park, Yong-Kon
    • Korean Journal of Food Science and Technology
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    • v.35 no.6
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    • pp.1221-1225
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    • 2003
  • As an effort to select powerful anti-cariogenic materials from natural resources, various plant extracts were examined for their anti-S. mutans and anti-glucosyltransferase (GTase) activities. The ethanol extracts of licorice bark, which was produced after water extraction of licorice, showed the most powerful anti-S. mutans as well as anti-GTase activities. When licorice bark was consecutively fractionated with n-hexane, chloroform, ethylacetate, and butanol, the chloroform fraction exhibited the strongest anti-S. mutans activites. This fraction was further fractionated into 4 fractions through a silica gel column, and according to HPLC analysis, anti-S. mutant activities seemed to come mostly from relatively hydrophobic materials.

Properties and Antimicrobial Activity of Egg Yolk Antibody(IgY) againt Food Poisoning Bacteria (Salmonella typhimurium) (식중독균 항원(Salmonella typhimurium)에 의하여 생성된 계란항체(IgY) 특성과 항균 효과)

  • 백반석;한준표;배만종
    • Journal of the East Asian Society of Dietary Life
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    • v.9 no.2
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    • pp.207-213
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    • 1999
  • This study was carried out to get a industrial information about a possibility of IgY antibody production, antimicrobial activity and properties of IgY antibody in egg yolk. The residual antibody activities of IgY were 91.5% after heating for 30min at 6$0^{\circ}C$. At the same time. these activities, were 73.2% after heating 15min at $65^{\circ}C$ and decreased vapidly at 7$0^{\circ}C$ and little antibody activity was left after heating for 15min at 8$0^{\circ}C$. When the prepared IgY was incubated at various pH ranges from 7 to 2 for 5hr at 37$^{\circ}C$., the antibody activity was stable from pH 7 to 4 and remained to 69.8% at pH 3.

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A Verification of Cosmetic Effect about Anti-oxidant and Anti-wrinkle of 11 Native Plants (자생식물 11종의 항산화 및 항주름에 관한 향장효능 검증)

  • Jang, Young-Ah
    • Journal of Life Science
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    • v.26 no.7
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    • pp.782-788
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    • 2016
  • To check the possibility of using natural extracts for cosmetic substances, we tested the bioactive effects of 11 crude extracts originating from native plants grown in the Republic of Korea on anti-oxidant and anti-wrinkle activities. When DPPH scavenging activities were measured, the crude extracts of Vitex rotundifolia, Scirpus triangulatus, S. wichurae, S. tabernaemontani, and Aeschynomene indica assays had more than 70% of DPPH scavenging activities at 100 μg/ml concentration. The data from the hydrogen peroxide scavenging assay revealed that the crude extracts from the 10 species, except for Eleocharis mamillata var. cyclocarpa, could scavenge more than 90% at 1,000 μg/ml concentration. The crude extract of V. rotundifolia had the highest xanthine oxidase scavenging activity at a 1,000 μg/ml concentration. Based on the four anti-oxidant assays, the crude extracts of V. rotundifolia, S. triangulatus, S. wichurae, S. tabernaemontani, and A. indica were shown to have excellent anti-oxidant capacities overall. In addition to the anti-oxidant capacities, the crude extract from S. wichurae exhibited high collagenase inhibitory activity, therefore, it could be a promising candidate for a cosmetic ingredient with anti-oxidant and anti-wrinkle qualities. The results of this study indicate that many wild plants native to the Korea Peninsula can be used as excellent natural substances for cosmetics based on their bioactive effects.