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Anticariogenic Activities of Various Plant Extracts  

Choi, In-Wook (Korea Food Research Institute)
Jung, Chang-Hwa (Korea Food Research Institute)
Park, Yong-Kon (Korea Food Research Institute)
Publication Information
Korean Journal of Food Science and Technology / v.35, no.6, 2003 , pp. 1221-1225 More about this Journal
Abstract
As an effort to select powerful anti-cariogenic materials from natural resources, various plant extracts were examined for their anti-S. mutans and anti-glucosyltransferase (GTase) activities. The ethanol extracts of licorice bark, which was produced after water extraction of licorice, showed the most powerful anti-S. mutans as well as anti-GTase activities. When licorice bark was consecutively fractionated with n-hexane, chloroform, ethylacetate, and butanol, the chloroform fraction exhibited the strongest anti-S. mutans activites. This fraction was further fractionated into 4 fractions through a silica gel column, and according to HPLC analysis, anti-S. mutant activities seemed to come mostly from relatively hydrophobic materials.
Keywords
anti-cariogenic; anti-S. mutans; anti-GTase; licorice;
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1 Hamada, S., Koga, T and Ooshima, T Virulence factors of Streptococcus mutans and dental caries prevention. J. Dent. Res. 63: 407-411 (1984)   DOI   PUBMED   ScienceOn
2 Degar, M.D. and Walker, G.J. Metabolism of the polysaccharides of human plaque. Caries Res. 9: 21-28 (1975)   DOI   ScienceOn
3 You, Y.S., Park, K.M. and Kim, Y.B. Antimicrobial activity of some medical herbs and spices against Streptococcus mutans. Korean J. Appl. Microbial. Biotechnol. 21: 187-191 (1993)
4 Cho, Y.J. Isolation of 3-galloylprocyanidin B_{3}, a glucosyltransferase inhibition from the Korean green tea leaves. Agri. Chem. Biotechnol. 43: 273-276 (2000)
5 Otake, S., Makimura, M., Kuroki, T., Nishihara, Y. and Hirasawa, M. Anticaries effects of polyphenolic compounds from Japanese green tea. Caries Res. 25: 438-443 (1991)   DOI   ScienceOn
6 Gibbon, R.J. and Van-Houte, J. On the formation of dental plaque. J. Periodontol. 44: 347-360 (1973)   DOI   PUBMED
7 Ueno, R., Matsuda, T., Tago, K., Kunimi, Y. and Kanayama, T. Antimicrobial agents with solubilizers for food preservation. Japanese Patent 60,233,015, 131-137 (1985)
8 Miyoshi, M., Imoto, T. and Kasagi, T. Antieurodontic effect of various fraction extracted from the leaves of gymnema sylvestre. J. Yonago Med. Ass. 38: 127-137 (1987)
9 Hamada, S., Ooshima, T, Torii, M., Imanishi, H., Masuda, N., Mizuno, J., Sobe, S. and Kotani, S. Dental caries induction in experimental animals by clinical strains of Streptococcus mutans isolated from Japanese children. Microbiol. Nmmunol. 22: 301314(1978)
10 Jang, G.H., Ahn, B.Y, Oh, S.H., Choi, D.S. and Kwon, Y.J. Anticariogenic effects of Coptis chinensis franch extract. Korean J. Food Sci. Technol. 32: 1396-1402 (2000)
11 Hamada, S. and Slade, H.D. Biology, immunology, and cariogenicity of Streptococcus mutans. Microbiol. Rev. 44: 331-384 (1980)   PUBMED
12 Anon. GRAS status of licorice (Glycyrrhiza), ammoniated glycyrrhizin and mono ammonium glycyrrhizinate. Federal Register. 48: 54983-54990 (1983)
13 Fenwick, G.R. Liquorice, Glycyrrhiza glabra L.-composition, uses and analysis. Food Chem. 38: 119-143 (1990)   DOI   ScienceOn
14 Saitoh, T., Kinoshita, T. and Shibata, S. New isoflavan and flavanone from liquorice root. Chem. Pharm. Bull. 24. 752-755 (1976)   DOI
15 Lutomski, J. Chemie und therapeutische verwendung von sussholz (Glycyrrhiza glabra L.). Pharm. Zeit 12: 49-54 (1983)
16 Ooshima, T., Izumitani, A., Minami, T., Yoshida, S. and Hamada, S. Noncariogenicity of maltitol in specific pathogen-free rats infected with mutans streptococci. Caries Res. 26: 33-37 (1992)   DOI   ScienceOn
17 Ooshima, T., Izumitani, A., Minami, T., Fujiwara, Y., Nakajima, Y. and Hamada, S. Trehalulose does not induce dental caries in rats infected with mutans streptococci. Caries Res. 25: 277-282 (1991)   DOI   ScienceOn
18 Maruzen Chemical Co. Ltd. Food antioxidants from liquorice extracts and gallic acid. Japanese Patent 60, 44, 580, 625-628 (1985)
19 Koga T., Okahashi, T, Asakawa, H. and Hamada, S. Adherence of Streptococcus mutans to tooth surface, pp. 111-120. In: Molecular Microbiology and Imunobiology of Streptococcus mutans. Hamada, S., Michalek, M., Kiyono, H., Menaker, L. and McGhee, J.R. (eds.). Elsevier Science Publishers, Amsterdam, Netherlands (1986)
20 Saitoh, T., Kinoshita, T. and Shibata, S. Flavonols of liquorice root. Chem. Pharm. Bull. 24. 1242-1245 (1976)   DOI
21 Nakahara, K., Kawabata, H.O., Ogura, K., Tanaka, T, Ooshima, T and Hamada, S. Inhibitory effect of oolong tea polyphenols on glucosyltransferases of mutans Streptococci. Appl. Environmental Microbiol. 4: 968-974 (1993)