• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.16 no.10
• /
• pp.6932-6939
• /
• 2015

The respiration is one of important factor in the radiation therapy. The existing commercial method of cone-beam computed tomography on LINAC does not consider respiratory motion of patient hence the images are both distorted and inaccurate. In this study, the cone-beam computed tomography images have been reconstructed from back projection radiography of specific phase on breathing cycle which concerned about respiratory movement in radiation therapy. This study investigated how different between cone-beam CT images with and without gating respiratory movement, and this paper provides that guide and implementation of gated cone-beam CT on radiation therapeutic equipment.

• Journal of Korean Academy of Nursing
• /
• v.28 no.3
• /
• pp.591-601
• /
• 1998

미숙아에 있어 주로 표면활성제의 부족으로 인한 호흡곤란증은 미숙아 사망의 주원인이 된다. 호흡곤란증의 치료목적은 적절한 환기를 통해 체내 산소화를 유지시키는 것이다. 인공호흡기 치료를 받는 미숙아에게 필수적인 간호중재인 기관지 흡인술은 그 효과를 극대화하기 위해 흉곽진동법과 같이 사용될 수도 있다. 그러나 미숙아를 대상으로 하는 흉곽진동법은 그 중재의 안전성이나 효과에 대한 과학적 검증 없이 시행되고 있는 실정이다. 이에 본 연구는 호흡곤란증 미숙아에 있어 기관지 흡인술 이전에 행하여지는 흉곽진동법이 산소화와 기관지 분비물에 미치는 영향을 연구하기 위해 실시되었다. 이를 위해 20명의 호흡곤란증 미숙아를 대상으로 대상자내 반복실험연구가 설계되었다. 독립변수는 기관지흡인술이전에 흉곽진동이고 종속 변수는 산소 포화도, 심박동수, 그리고 기관지 분비물의 양이었다. 각 대상자는 무작위 순서에 따라 한번은 흉곽진동없이 흡인을, 나머지 한번은 흉곽진동과 흡인의 두 가지 형태의 흡인을 경험 하였다. 연구 결과, 기관지 흡인술이전에 흉곽진동을 실시하든, 안하든 산소포화도와 심박동수의 변화양상에는 차이가 없었다. 그러나, 융곽진동법을 실시한 경우가 실시안한 경우에 비해 더 많은 양의 기관지 분비물을 흡인하였다. 이는 기관지 흡인술 이전에 실시하는 흉곽진동법이 미숙아의 체내에 부가적 산소소모를 초래하지 않는 반면, 기도로부터 더 많은 분비물을 흡인하는데 효과적임을 시사한다.

• Journal of the Institute of Electronics and Information Engineers
• /
• v.51 no.12
• /
• pp.111-122
• /
• 2014

As radiotherapy has become one of the widely used techniques in cancer treatment, accurate tracking of patient's respiratory motion is considered to be more important in treatment planning and dose calculations. Inaccurate motion tracking can cause severe issues such as errors in target/normal tissue delineation and increasing the volume of healthy tissues exposed to high doses. Different methods have been introduced to estimate the respiratory motion, but most of them require some electronic devices or expensive materials. As an inexpensive and easy to use alternative to the previous methods, we propose a new 3D respiratory motion tracking method by using stereo vision techniques of detecting and decoding visual coded markers.

• Proceedings of the KOR-BRONCHOESO Conference
• /
• 1976.06a
• /
• pp.87.3-87
• /
• 1976

The authors experienced a case of a difficult decannulation in a 4 years old boy, in which. case decannulation was possible 2 years later a tracheostomy. Some immunoglogical phenomena could be considered in this case as though cancer can remiss spontaneously. Such complications of tracheostomy as subglottic edema and perichondritis could become relatively less troublesome to breathing during his aging process. And another reason for the easy decannulation is considered as the patient could be accustomed to breathing through natural air pathway by continual cannula corking training.

• Tuberculosis and Respiratory Diseases
• /
• v.64 no.3
• /
• pp.206-209
• /
• 2008

Tracheal tuberculosis is a relatively uncommon form of tuberculosis and can result in acute tracheal obstruction early in the disease course. This is a report of a case of tracheal tuberculosis with unusual clinical presentation.

• Journal of Dental Rehabilitation and Applied Science
• /
• v.29 no.4
• /
• pp.391-398
• /
• 2013

Botulinum toxin has been used for treating strabismus, blepharospasm, cerebral palsy, cervical dystonia, hyperhydrosis, facial wrinkle and chronic migraine under US Food and Drug administration approval. Also it has been tried spasticity-induced pain, post-herpetic neuralgia, myofascial pain and aphthous ulcer as off-label use. In this study, we reviewed recent studies that suggested effects of botulinum toxin on snoring and sleep apnea.

• Proceedings of the IEEK Conference
• /
• 2003.07c
• /
• pp.2883-2886
• /
• 2003

좋은 발성을 위하여 음성이 만들어지려면, 뇌의 언어중추의 명령에 의하여 신경망을 통하여 ‘호흡기관(폐와 흉곽. 호흡관련 근육들)’과 ‘발성기관(주로 후두 즉 성대)’ 그리고 ‘조음, 공명기관(인두, 구강 및 비강)’의 근육들이 유기적으로 작용하여야 한다. 이런 협력 체제에 문제가 생기면, 다양한 종류의 질환이 유발될 수 있다[1,2]. 현재 임상에서 음성 분석을 위해 사용되는 시스템은 대부분 성대의 진동을 측정하기 위해 stroboscopy, 전기성문파형검법 (EGG, electroglottography), 후두근전도 중의 한 방법과 음성 분석을 위한 분석 프로그램으로 구성되어 있다. 그러나, 발성은 호흡과 매우 밀접한 관계가 있어 음성, 성대의 진동, 호흡 관계를 종합적으로 관찰할 필요가 있다. 본 연구에서는 발성 시 성대 점막의 접촉 양상은 ECG 로 측정하며, 발성의 주 에너지원이 되는 호흡의 변화를 2 channel 인덕턴스 호흡감시 장치(RIP: repiratory inductive plethymography)를 이용하여 흉곽의 움직임과 상 복강의 움직임에 대하여 측정하며, 발성되는 음성은 마이크로폰을 통하여 측정하는 ‘EGG, 음성, 호흡 통합검사 장치’를 개발하였다.

• Radiation Oncology Journal
• /
• v.27 no.4
• /
• pp.228-239
• /
• 2009

Purpose: 4DCT scans performed for radiotherapy were retrospectively analyzed to assess the possible benefits of respiratory gating in non-small cell lung cancer (NSCLC) and established the predictive factors for identifying patients who could benefit from this approach. Materials and Methods: Three treatment planning was performed for 15 patients with stage I~III NSCLC using different planning target volumes (PTVs) as follows: 1) PTVroutine, derived from the addition of conventional uniform margins to gross tumor volume (GTV) of a single bin, 2) PTVall phases (patient-specific PTV), derived from the composite GTV of all 6 bins of the 4DCT, and 3) PTVgating, derived from the composite GTV of 3 consecutive bins at end-exhalation. Results: The reductions in PTV were 43.2% and 9.5%, respectively, for the PTVall phases vs. PTVroutine and PTVgating vs. PTVall phases. Compared to PTVroutine, the use of PTVall phases and PTVgating reduced the mean lung dose (MLD) by 18.1% and 21.6%, and $V_{20}$ by 18.2% and 22.0%, respectively. Significant correlations were seen between certain predictive factors selected from the tumor mobility and volume analysis, such as the 3D mobility vector, the reduction in 3D mobility and PTV with gating, and the ratio of GTV overlap between 2 extreme bins and additional reductions in both MLD and $V_{20}$ with gating. Conclusion: The additional benefits with gating compared to the use of patient-specific PTV were modest; however, there were distinct correlations and differences according to the predictive factors. Therefore, these predictive factors might be useful for identifying patients who could benefit from respiratory-gated radiotherapy.

• The Journal of Korean Society for Radiation Therapy
• /
• v.24 no.1
• /
• pp.15-21
• /
• 2012

Purpose: Image Guided Radiation Therapy (IGRT) has been carried out using On-Board Imager system (OBI) in Asan Medical Center. For this reason, This study was to analyze and evaluate the impact on Cone-Beam CT according to variation of material and respiration. Materials and Methods: This study was to acquire and analyze Cone-Beam CT three times for two material: Cylider acryl (lung equvalent material, diameter 3 cm), Fiducial Marker (using clinic) under Motion Phantom able to adjust respiration pattern randomly was varying period, amplitude and baseline vis-a-vis reference respiration pattern. Results: First, According to a kind of material, when being showed 100% in the acryl and 120% in the Fiducial Marker under the condition of same movement of the motion phantom. Second, According to the respiratory alteration, when being showed 1.13 in the baseline shift 1.8 mm and 1.27 in the baseline shift 3.3 mm for acryl. when being showed 1.01 in 1 sec of period and 1.045 in 2.5 sec of period for acryl. When being showed 0.86 in 0.7 times the standard of amplitude and 1.43 in 1.7 times the standard of amplitude for acryl. when being showed 1.18 in the baseline shift 1.8 mm and 1.34 in the baseline shift 3.3 mm for Fiducial Marker. when being showed 1.0 in 1 sec of period and 1.0 in 2.5 sec of period for Fiducial Marker. When being showed 0.99 in 0.7 times the standard of amplitude and 1.66 in 1.7 times the standard of amplitude for Fiducial Marker. Conclusion: The effect of image size of CBCT was 20% in the case of Fiducial marker. The impact of changes in breathing pattern was minimum 13% - maximum 43% for Arcyl, min. 18% - max. 66% for Fiducial marker. This difference makes serious uncertainty. So, Must be stabilized breathing of patient before acquiring CBCT. also must be monitored breathing of patient in the middle of acquire. If you observe considerable change of breathing when acquiring CBCT. After Image Guided, must be need to check treatment site using fluoroscopy. If a change is too big, re-acquiring CBCT.

• Radiation Oncology Journal
• /
• v.19 no.4
• /
• pp.319-326
• /
• 2001

Purpose : Planning target volume (PTV) for tumors in abdomen or thorax includes enough margin for breathing-related movement of tumor volumes during treatment. Depending on the location of the tumor, the magnitude of PTV margin extends from 10 mm to 30 mm, which increases substantial volume of the irradiated normal tissue hence, resulting in increase of normal tissue complication probability (NTCP). We developed a simple and handy method which can reduce PTV margins in patients with liver tumors, respiratory motion reduction device (RRD). Materials and methods : For 10 liver cancer patients, the data of internal organ motion were obtained by examining the diaphragm motion under fluoroscope. It was tested for both supine and prone position. A RRD was made using MeV-Green and Styrofoam panels and then applied to the patients. By analyzing the diaphragm movement from patients with RRD, the magnitude of PTV margin was determined and dose volume histogram (DVH) was computed using AcQ-Plan, a treatment planning software. Dose to normal tissue between patients with RRD and without RRD was analyzed by comparing the fraction of the normal liver receiving to $50\%$ of the isocenter dose. DVH and NTCP for normal liver and adjacent organs were also evaluated. Results : When patients breathed freely, average movement of diaphragm was $12{\pm}1.9\;mm$ in prone position in contrast to $16{\pm}1.9\;mm$ in supine position. In prone position, difference in diaphragm movement with and without RRD was $3{\pm}0.9\;mm$ and 12 mm, respectively, showing that PTV margins could be reduced to as much as 9 mm. With RRD, volume of the irradiated normal liver reduced up to $22.7\%$ in DVH analysis. Conclusion : Internal organ motion due to breathing can be reduced using RRD, which is simple and easy to use in clinical setting. It can reduce the organ motion-related PTV margin, thereby decrease volume of the irradiated normal tissue.