• Tuberculosis and Respiratory Diseases
• /
• v.49 no.1
• /
• pp.18-29
• /
• 2000

호흡기 바이러스 감염은 모든 연령층의 천식에 상당한 영향을 미치는 데 영아에서 RSV는 천명을 야기하고 대부분 일시적이나 재발성 일수도 있다. 어릴 때 바이러스 감염은 면역체계 형성에 영향를 미쳐 알러지와 천식의 위험을 완하할 수있다고 한다. 또한 소아와 성인 천식에서 RV같은 감기 바이러스는 천식의 급성 증상을 유발한다. 호흡기 바이러스 감염에 대한 면역반응이, 기관지로 부터 바이러스 제거 기능외에 기도수축과 호흡기 증상에 관여한다고 한다. 이러한 변화가 일어나는 기전은 호흡기 바이러스가 proinflammatory 사이토카인과 매개체 생성을 유도하는 능력과 연관성이 있는 것 같고 이들이 상하기도 호흡기 증상 및 기도반응 변화에 관여하는 것으로 생각된다. 호흡기 바이러스 감염에 대한 면역반응을 요약하면 바이러스 감염으로 상피세포, 내피세포, 과립백혈구가 활성화되며, 상피세포는 사이토카인, 키모카인, 매개체들을 분비하여 항 면역 반응를 주도하다. 이와 같은 상피세포와 다른 기관지 세포들의 조기 활성화로 내피 세포에 유착분자 표현을 증가시켜 백혈구 동원 증가 및 혈관 투과성을 증가시켜 부종과 분비물을 증가시킨다. 바이러스 또는 바이러스 유발 사이토카인에 의해 활성화된 과립 백혈구, 대식세포, T세포들도 기도염증 증가, 기도폐쇄를 야기하고 기도반응을 증가시킨다. 세포독성 임파구에 의한 바이러스 감염세포의 분해, TGF-$\beta$ IL-10 같은 사이토카인에 의해 부분적으로 염증억제, 기도 remoldeling에 의한 기도구조의 재생등이 바이러스 감염후 기관지 기능의 지속적 변화를 결정한다. 끝으로 천식환자에서 RV 감염의 병인에 관한 기본적 문제는 RV감염이 정상인에서는 경한 증상을 나타내는 데 천식환자에서는 왜 심한 임상증상을 나타내는지 아직 완전히 밝혀지지 않았다. 항 바이러스에 대한 면역반응이 천식환자에서 손상되었는지 또는 천식환자에서 RV감염에 의한 중증의 임상증상은 어떤 다른 세포가 관여하는지? 이들에 대한 답은 기도염증이 천식에서 어떻게 조절되는지 또한 바이러스 감염에 의한 악화된 증상을 어떻게 치료할 것인가에 대한 방향을 제시해줄 것이다.

• Clinical and Experimental Pediatrics
• /
• v.51 no.7
• /
• pp.729-735
• /
• 2008

Purpose : Chlamydia trachomatis is one of the most common sexually transmitted diseases and is also a cause of pneumonia in infants. Respiratory infections by respiratory viruses are also common for infants. The objectives of this study were to identify the clinical manifestations and to determine the prevalence of C. trachomatis respiratory infections and coinfections by respiratory viruses in infants younger than 6 months of age. Methods : For this study, we enrolled 6 months or younger infants who were admitted to the Dankook University Hospital between January 2002 and July 2007, with respiratory symptoms. Nasopharyngeal aspirates or throat swabs were collected within s d of hospitalization and C. trachomatis was detected using polymerase chain reaction (PCR). Patients who tested positive underwent multiplex PCR for respiratory viruses. Results : A total of 690 patients underwent chlamydial PCR testing and 36 (5.2%) had positive results. Of the 36, 28 (78%) were male; 30 were vaginally delivered. From the 36 patients positive for C. trachomatis, 26 underwent multiplex respiratory viral PCR; 12 were coinfected with viruses. Respiratory syncytial virus (RSV) was the most frequent pathogen that was detected in 6 patients. Increased C-reactive protein and fever were significant in patients coinfected with respiratory viruses. Conclusion : C. trachomatis can infected in infants delivered by cesarean section as well as in 6 months old or younger infants. Infant with C. trachomatis respiratory infections can also be coinfected with respiratory infection also coinfected with respiratory viruses. Further studies are needed to better understand the prevalence rates of the this infection and its coinfection rate with respiratory viruses.

• KOREAN POULTRY JOURNAL
• /
• v.37 no.6 s.428
• /
• pp.138-139
• /
• 2005

산란계든 육계든 호흡기 감염은 생산성을 저하시킨다. 호흡기 감염은 세균, 기생충, 바이러스 등 다양한 감염원에 의해 유발되지만 외형상 나타나는 증상은 비슷하기 때문에 정확한 진단과 처방이 요구된다. 본고에서는 비 바이러스성 가금 호흡기 질병들을 알아보기로 한다.

• Korean Journal of Clinical Laboratory Science
• /
• v.53 no.1
• /
• pp.11-18
• /
• 2021

Respiratory viruses (RVs) cause infections in hospital environments through direct contact with infected visitors. In infection control, it causes major problems of acquired infections in hospitals by respiratory viruses. The surveillance data derived from clinical laboratories are often used to properly allocate medical resources to hospitals and communities for treatment, consumables, and diagnostic product purchases in the institutions and public health sectors that provide health care. An early diagnosis is essential in infection with respiratory viruses, and methods that can be used in diagnostic methods using respiratory samples include virus culture, molecular diagnosis, and analysis. A microchip provides a new strategy for developing a more diverse and powerful technology called point-of-care testing. The importance of the respiratory system should be applied strictly to the infection control guidelines to ensure the occupational health and safety of health care workers. Evidence of clinical efficacy, including this study, is challenging the long-standing paradigm for infection propagation. Additional assistance will be needed for frequent tests to detect respiratory viruses in inpatients who have begun to show new respiratory symptoms indicating infections requiring efforts to control the infection.

• The Monthly Diabetes
• /
• s.240
• /
• pp.14-16
• /
• 2009

인슐린과 항생제가 만들어지기 전에는 당뇨병환자들은 여러 가지 감염, 특히 폐렴으로 인한 입원과 사망률이 높았었다. 당뇨병환자들은 면역기능이 감소되어 있어서 당뇨병이 없는 환자들에 비하여 호흡기 감염이 여전히 더 잘 생길 수 있고 입원률과 사망률도 일반인에 비하여 더 높다. 우리나라의 중요한 호흡기 감염질환은 폐렴과 폐결핵이다. 이 2가지 질환과 당뇨병과의 관계 및 당뇨병환자에서 독감과 폐렴구균에 대한 예방접종의 효과와 필요성에 대하여 알아보자.

• Pediatric Infection and Vaccine
• /
• v.24 no.3
• /
• pp.188-192
• /
• 2017

Respiratory syncytial virus (RSV) typically causes lower respiratory tract infections in children, and most patients recover successfully. However, some infants and young children can have a severe course of disease with respiratory failure, and extrapulmonary manifestations can occur in severe RSV disease. We report one case of severe RSV bronchiolitis complicated with acute myocarditis, fulminant hepatic failure, and disseminated intravascular coagulation.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.20 no.8
• /
• pp.93-101
• /
• 2019

This study was conducted to develop a simulation-based education program for respiratory infectious disease and to identify the effects of clinical competency, self-leadership and critical thinking after applying to nursing students. A non-equivalent pre-post test of quasi-experimental design was used. The study subjects were 30 students for the experimental group and 30 for the control group. Respiratory infectious disease simulation-based education was provided for 5 weeks. Data analysis was performed using SPSS WIN Ver 21.0 with Fisher's exact test, independent t-test, and paired t-test. Clinical competency, self-leadership, and critical thinking of the experimental group showed statistically significant differences in comparison with the control group. These study results proved that a simulation-based education program for respiratory infectious disease is effective in raising nursing students' clinical competency, self-leadership and critical thinking. Therefore, it is considered that simulation-based education should be provided to cultivate nursing problem-solving clinical competency, self-leadership or critical thinking by developing a scenario based on various clinical situations.

• Journal of Practical Engineering Education
• /
• v.15 no.2
• /
• pp.449-457
• /
• 2023

The purpose of this descriptive research study was to investigate health beliefs and self-efficacy in respiratory infection management as factors that affect the respiratory infection prevention behavior of college students. The subjects were 178 students attending a university in K city of Gyeongsangbuk-do. Data were collected with a structured questionnaire from September 1st to October 16th of 2020. The results of this study are as follows; Health belief was significantly different from participant's gender (t=-2.86, p=.005), major classification (F=2.95, p=.034), and taking any medications (t=2.18, p=.030). Self-efficacy in respiratory infection management was significantly different from university students' gender (t=-3.56, p=<.001) and major classification (F=4.59, p=.004). Health belief (r=.276, p<.001) and self-efficacy in respiratory infection management (r=.660, p<.001) had a positive correlation with respiratory infection preventive behavior. Multiple regression analysis results show that self-efficacy in respiratory infection management (β=.66, p<.001) significantly affected respiratory infection preventive behavior. The model had an explanatory power of 43%. The findings demonstrate that the major factor influencing the respiratory infection preventive behavior of university students is self-efficacy in respiratory infection management. Therefore, in order to promote behavior to prevent respiratory infection in college students, a program that can strengthen self-efficacy in respiratory infection management should be developed.

• Journal of Digital Convergence
• /
• v.15 no.10
• /
• pp.315-326
• /
• 2017

This purpose of this study was to identify factors influencing performance about practice of infections management by child care center teachers about respiratory tract infection. The participant were 432 teachers working in child care center. Data were collected from July 2 to August 20, 2015 through a self-report questionnaire survey. The data was analyzed using the SPSS/WIN 18.0 program with descriptive analysis, t-test, one-way ANOVA, Pearson's correlation coefficient and Stepwise multiple regression analysis. Knowledge about causes and symptom of respiratory tract infections(${\beta}=.096$, p<.001),parenting experience(${\beta}=-1.993$, p<.001), and nursing knowledge(${\beta}=-.371$, p<.001) had significant positive effects on the practice of infection management. Explained variance for the practice of infection management was 43.4% and nursing knowledge was the most significant factor in the practice of infection management of child care center teachers.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.20 no.2
• /
• pp.721-731
• /
• 2019

The purpose of this study was to investigate the knowledge, attitude, infection management intention and educational needs among nurses with no experience of new respiratory infectious diseases (NRID: SARS and MERS). Data were collected from 162 nurses working at the general hospitals in B city using structured questionnaires from October 10 to 31, 2017. The infection management intention of NRID was high in those who were over 30 years old, married, highly educated, and had a total working experience of more than 5 years. Nurses' infection management intention for NRID showed a positive correlation between knowledge of NRID (r=.27, p<.001) and attitude toward NRID (r=.65, p<.001). In other words, the higher the knowledge score for NRID, the more positive the attitude and the higher the infection management intention. In addition, the knowledge score related to incubation period, treatment, isolation, and release criteria was low while the educational needs were high. Therefore, in preparation for the possibility of NRID relapse and other NRID in the future, a systematic program addressing these educational needs for nurses should be periodically implemented to enhance infection management.