• Clinical and Experimental Reproductive Medicine
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• 제12권1호
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• pp.31-40
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• 1985

월경주기 중 황체기가 짧은 여성 즉 황체기 단축현상을 가진 한국여성(SLP) 의 특성을 조사하고 진단하는 방법을 개발하기 위하여 본 실험을 행하였다. 재료는 정상 월경주기를 가진 12명의 여성에서 26주기와 8명의 황체기 단축현상을 가진 여성에서 17주기를 선택하였다. 기상후 첫 오줌에서 steroid glucuronides의 농도를 측정하여 비교한 결과는 다음과 같았다. SLP 의 estrone -3 -glucuronide ($E_1G)의 농도는 초기 여포기와 황체기 동안 정상인에 비하여 현저히 낮았다. 또한 SLP 의 전 월경기 중 pregnanediol-$3{\alpha}$-glucuronide($P_2G$)의 농도 역시 유의성있게 낮았다. 그러나 $E_1G/P_2G$의 비율은 여포기가 황체기에 비하여 현저히 높았고, SLP 여성의 비율이 정상인 보다 각 월경주기 중 유의성있게 높았다. 위의 결과로 보아 $E_1G$, $P_2G$및 $E_1G/P_2G$의 농도차로 황체기 단축현상을 가진 여성을 진단 하고 또 치료시 난소의 기능조절에 이욜될 수 있을 것으로 사려된다.

• Clinical and Experimental Reproductive Medicine
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• 제17권1호
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• pp.65-70
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• 1990

Clinical effects of intramuscular injection of 250mg testosterone cypionate every 2-3 weeks were investigated in 15 impotent patients with low or low normal serum testosterone level (Hypo-gonadotrophic hypogonadism was excluded). The results were obtained as follows. 1. Among 15 patients, 7(46.7%) showed markedly improved potency, 6(40%) partially improved potency and 2(13.7%) no improvement of potency. There was no correlation between effec-tiveness of testosterone replacement and age, testicular size, serum testosterone level or LH, FSH level. 2. Among 12 patients who had showed improved potency, 8(66.7%) complained of redeveloped decrease in potency during testosterone replacement. In conclusion, testosterone cypionate for treatment of the impotent patients with low or low normal serum testosterone level was effective, but further studies are necessary to investigate cause of redeveloped decrease in potency during testosterone replacement.

• 대한한방부인과학회지
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• 제29권3호
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• pp.68-77
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• 2016

Objectives: This paper is to report a spontaneous pregnancy with low AMH level and thin endometrium infertility after Korean medical treatments.Methods: A 38-year old patient who had low AMH level, thin endometrium, sleep disturbance and anxiety happened after anorectal cancer surgery was treated by korean medicine such as herb medications per day for 6 months. And we observed the effects of treatments by improvement of symptoms checking endometrium ultrasonography.Results: After treatments, Symptoms of anxiety and sleep disturbance were improved. The number of ovarian follicle and endometrium thickness were upgraded during artificial pregnancy trials. Finally the patient was a spontaneous pregnancy after failures of one intrauterine insemination and one in vitro fertilization trial.Conclusions: This case shows that the korean medicine has effective option for a patient with low AMH level and thin endometrium infertility. Further ultrasonography would be valid measurements to check the effectiveness of oriental treatments as well as symptoms.

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 2004년도 추계학술대회 논문집
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• pp.1278-1281
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• 2004

Several workers reported the relationship between osteoporosis and age-related reductions in the BV/TV (bone volume fraction) of vertebral trabecular bones. However, there were few micro finite element (micro-FE) models to account for the treatments of the osteoporotic trabecular bone. In the present study, micro-FE models of osteoporotic and hormone-treated bone models were constructed to analyze the effect of specimen location and boundary condition on mechanical characteristics of hormone treatment model for osteoporotic trabecular bone. Top and bottom sections of specimens were also investigated individually to study the effect of specimen location. Hormone-treated models were allowed to have the same relative BV/TV (13.4％) as that used in models of previous researchers. The present study reported the elastic and plastic characteristics of the osteoporosis and hormone-treated bone models. In the present study, in-situ boundary condition was applied to the simulated compression tests for in-vivo condition of vertebral trabecular bone. The present study indicated that the hormone therapy was likely to improve the mechanical characteristics of osteoporotic bones and the mechanical characteristics of vertebral trabecular bone specimen were dependent on the captured location and boundary condition.

• Journal of Chest Surgery
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• 제42권1호
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• pp.119-122
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• 2009

융모막암종은 생식 세포 종양의 일종으로 베타 인간 융모막 생식샘 자극 호르몬을 분비하는 합포체성 융모영양막세포에서 발생하는 종양이다. 주로 생식기에 발생하는 것이 일반적이며 폐장에 발생하는 경우는 매우 드문 것으로 알려져 있다. 본원에서는 28세 여자환자에서 발생한 원발성 폐 융모막암종이 의심되는 환자에서, 수술적 절제술을 시행하여 원발성 폐 융모막암종임을 확인하였고, 수술 후 추가적인 치료 없이 2년간 재발의 증거 없이 생존하고 있어 이를 보고한다.

• 대한한방부인과학회지
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• 제28권2호
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• pp.174-182
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• 2015

Objectives : AMH (Anti-Müllerian Hormone) is considered a sensitive marker of ovarian reserve, and it tends to be included among basic fertility tests. This paper is to report four pregnancies which were achieved by subfertile women with low AMH level after Korean medical treatments. Methods : Four cases of pregnancy by subfertile women, aged 34 to 37, with low AMH level (0.04 to 0.76 ng/mL), after Korean medical treatments between July 2012 and May 2015, were analysed. The patients were diagnosed as Kidney deficiency (腎虛), Blood extravasation (瘀血) and/or Liver Qi stagnation (肝氣 鬱結). Herbal medicine, acupuncture, pharmacopuncture and moxibustion treatments were applied. Results : The four subfertile women with low AMH level achieved pregnancy after Korean medical treatments. Conclusions : The case report suggests that Korean medical treatment can be an effective option for subfertile women with low AMH level before Assisted Reproductive Technology.

• 대한두경부종양학회지
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• 제12권2호
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• pp.235-240
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• 1996

갑상선 유두암에 의한 뇌전이는 극히 드물게 발견되어며 그 진단 및 치료방법의 설정이 아직 확립되어 있지 못한 상태이다. 저자들은 갑상선 유두암으로 5년전 갑상선 전절제술을 시술받고 갑상선 호르몬 복용을 하고 있던 24세의 남자에서 간헐적인 발작을 일으킨 전두골내 병소가 갑상선 유두암의 전이에 의한 것임을 조직학적으로 확인할 수 있었다. 이 병소는 전신 요오드 주사상에서는 나타나지 않았지만 Brain CT 및 MRI 소견으로만 병변의 진단이 가능하였으며 stereotactic cranitomy에 의한 종양제거로 비교적 만족스러운 결과를 얻어 현재 밀착추적중에 있다.

• 한방안이비인후피부과학회지
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• 제29권1호
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• pp.157-167
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• 2016

Objective : The purpose of this study is to know the effect of Korean medical treatments on sudden sensorineural hearing loss(SSNHL) without systemic or intratympanic steroid treatments.Method : We conducted retrospective review who was diagnosed as SSNHL and treated with Korean medicine in Dept. of Otolaryngology Kyung Hee University Hospital at Gangdong. There were two patients with SSNHL who refused to be treated with western medicine and were treated with Korean medicine including acupuncture, moxibustion, and herbal medicine.Result : One patient recovered completely after eight days of admission, and another patient partial recovered during 30 days through Korean medical treatments.Conclusion : Through these studies, SSNHL is expected to treated more effectively by conventional Korean medical treatments than corticosteroid treatments alone. But the additional study is needed to reveal the exact effects of Korean medical treatments.

• 대한통합의학회지
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• 제6권4호
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• pp.183-189
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• 2018

Purpose : As age increases, a low-level systemic inflammatory state develops and the levels of anti-aging hormones decrease. The vagus nerve activates parasympathetic nerves and promotes sulfation and secretion of neurotransmitter in the brain. Therefore, the purpose of this study was to investigate the effects of electrical vagus nerve stimulation on systemic inflammation (CRP) and anti-aging hormone (DHEA-S) levels in elder people. Methods : A total of 30 healthy elder people participated in this study, randomly divided into two groups of 15 subjects. Electrical vagus nerve stimulation was applied to the experimental group for 4 weeks. CRP and DHEA-S levels were compared with those of the control group. Results : The CRP level was significantly lower in the experimental group than in the control group. In the experimental group, there was a significant decrease in CRP before and after the intervention. However, the DHEA-S level was not significantly different between groups. Conclusion : Electrical vagus nerve stimulation may alleviate the low-level systemic inflammatory state found in elderly people. These results suggest that it may have the effect of reducing the degenerative inflammatory diseases of the elderly and delaying aging.

• 대한핵의학회지
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• 제33권6호
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• pp.493-501
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• 1999

목적 : 분화된 갑상선암에서 암 절제술 및 방사성 옥소 치료 후 추적관찰 중 재발이나 전이병소를 찾기 위한 효과적인 검사 방법에 대한 자료를 제시하고자 T1-201 스캔, Tc-99m MIBI 스캔, I-131 스캔 검사의 결과를 비교하였다. 대상 및 방법: 분화된 갑상선암으로 진단되어 수술 및 방사성 옥소로 치료 후 추적관찰 중 국소 재발 또는 전이로 생각되어 한번이상의 방사성 옥소 재 치료를 시행한 20명(총 33예)의 환자를 대상하여 T1-201 스캔, Tc-99m MIBI 스캔, 진단적 및 치료적 I-131 스캔을 시행하여 각 스캔에서 결과를 후향적으로 분석하였다. 모든 환자에서 갑상선글로불린을 측정하였고 임상적, 방사선학적, 조직학적 검사로 암의 재발 및 전이를 확인하였다. 결과: 4가지 검사의 비교에서 병소를 발견할 수 있는 양성률은 Tc-99m MIBI 스캔, T1-201 스캔, 진단적 I-131 스캔, 치료적 I-131 스캔에서 각각 70% (19/27), 54% (15/28), 35% (17/48), 63% (30/48)였다. T1-201 스캔과 I-131 스캔을 같이 시행한 군(20 예, 28병소)에서는 병소의 양성률은 치료적 I-131 스캔, T1-201 스캔, 진단적 I-131 스캔 순으로 높았으나(71%, 54%, 36%), T1-201 스캔과 진단적 I-131 스캔간의 차이는 없었다(p>0.05). Tc-99m MIBI 스캔을 I-131 스캔과 같이 시행한 군(20예, 27병소)에 서는 Tc-99m MIBI, 치료적 I-131 스캔, 진단적 I-131 스캔의 순으로 높았고(70%, 52%, 33%), Tc-99m MIBI는 진단적 I-131 스캔보다 양성률이 유의하게 높았다(p<0.05). 결론: 분화된 갑상선암 환자의 치료 후 추적 관찰에서 국소 재발 및 전이 병소를 찾는데 Tc-99m MIBI 스캔은 진단적 I-131 스캔보다 우수하였다. 따라서 치료 전에 진단적 I-131 스캔을 시행하기보다는 갑상선 호르몬제를 중단하지 않은 상태에서 Tc-99m MIBI 스캔을 시행한 후 결과에 따라서 치료용량의 방사성 옥소를 투여하고 치료적 I-131 스캔을 하는 것이 효과적일 것으로 사료된다.