• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2011.10a
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• pp.462-465
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• 2011

A pulse oximeter is a device which provides non-invasive estimate of percentage oxygen saturation of haemoglobin (SpO2). Due to the limitations of resources of personal health devices (PHDs) including pulse oximeters, they generally transmit the estimated data to a remote monitoring server through a close manager (e.g. mobile device or PC). Therefore, communication protocols between PHDs and a manager is an important research topic in terms of interoperability. In this paper, we present design results of an SpO2 transmission agent based on the ISO/IEEE 11073 (X73) protocol. The protocol is an international standard for PHDs. The agent is an embedded program which generates X73 messages from the estimated pulse rates and SpO2, and transmits the messages to a close manager. The agent consists of a Session, Message and Memory Handler. The Session Handler manages a communication session with the manager, and the Message Handler generates and analyzes the exchanged messages according to the X73 protocol. The Memory Handler extracts pulse rates and SpO2s which are stored in a memory of the pulse oximeter. The SpO2 transmission agent allows pulse oximeters to communicate with managers based on x73 standard. Consequently, the interoperability between the pulse oximeters and the managers is guaranteed.

• Proceedings of the KSPS conference
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• 2007.05a
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• pp.261-264
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• 2007

Five males trained singers (age:25.0${\pm}$1.4years, career:6.8${\pm}$1.1 years) and five female trained singers (age:22.0${\pm}$1.0years, career:5.8${\pm}$1.2 years) participated in this study. SaO2(Oxi Hemoglobin saturation) measured by Oxy-Pulse meter and PAC02 (Pressure Alveolar Co2) measured by Quick et CO2 are compared with pre and post vocal training. As the result, PAC02 was lower than normal range (36-40mmHg) after vocal training, leading to Hypocapnia. This causes headache and dizziness

• Aerospace Engineering and Technology
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• v.8 no.1
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• pp.207-214
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• 2009

The purpose of this study was to examine the influence of hypoxic exercise at head down tilt (HDT) on cardiovascular responses. Eight men ($23{\pm}2$ yrs, $176{\pm}4$ cm, and $75{\pm}8$ kg) underwent four separate exercise testing sessions; seated normoxia (SN), seated hypoxia (SH), HDT normoxia (HN), and HDT hypoxia (HH). Each participant performed the leg cycling at predetermined 40% of maximal aerobic capacity relevant to each posture for 15 min. Heart rate was higher in SH than SN and higher also in HH than SH (p<0.05). Blood oxygen saturation was lower in SH than SN (p<0.05). During resting, diastolic blood pressure and mean arterial pressure was significantly lower in HDT than seated posture (p<0.05). No differences were found between conditions in hemoglobin and hematocrit and electrolytes including, sodium, potassium, and chloride. Lactate was higher in SH than SN. In conclusion, there was no effect for cardiovascular responses to duplicate stimuli both hypoxia and posture.

• Sleep Medicine and Psychophysiology
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• v.7 no.1
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• pp.43-50
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• 2000

Objectives: Obstructive sleep apnea syndrome(OSAS) is known to be associated with the changes of autonomic nervous system (ANS). Nasal continuous positive airway pressure(nCPAP) treatment was found to correct abnormal ANS changes in OSAS but it remains to be further clarified. We aimed to assess the effects of nCPAP on ANS manifested on electrocardiogram, using spectrum analysis in the subjects with OSAS. Methods: Digital polysomnography was performed in 18 patients with OSAS(mean age $43.7{\pm}16.6$ years ; 17 males, 1 female ; mean respiratory disturbance index (RDI) $48.6{\pm}20.9$) for one baseline and another CPAP nights. From each night, 300 continuous beats of ECGs without artifact were chosen from both stage 2 sleep and REM sleep and they were used for power spectrum analysis. We compared between baseline and CPAP nights the heart rate variability including VLF(very low frequency power), LF (low frequency power), HF(high frequency power), R-R means, R-R variance, and LF/HF ratio, using Wilcoxon signed ranks test. Results: In all patients, nCPAP proved to be effective in relieving apneas and snoring. During nCPAP night compared with baseline night, decreases in VLF(p<0.05), LF(p<0.01), and R-R variance(p<0.05) were found in stage 2 sleep, and decreased LF(p<0.05) was found in REM sleep. No significant differences in each sleep stage were found in other variables between the two nights. Conclusion: Our findings suggest that OSAS increases the activity of sympathetic nervous system and nCPAP application effectively decreases the activity. And nCPAP does not appear to influence the parasympathetic nervous activity in OSAS.

• Journal of Yeungnam Medical Science
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• v.15 no.1
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• pp.97-113
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• 1998

The sympathoadrenal system plays an important role in homeostasis in widely varing external environments. Conflicting findings, however, have been reported on its response to hypoxia. We investigated the effect of hypoxia on the sympathoadrenal system in dogs under halothane anesthesia by measuring levels of circulating catecholamines in response to graded hypoxia. Ten healthy mongreal dogs were mechanically ventilated with different hypoxic gas mixtures. Graded hypoxia and reoxygenation were induced by progressively decreasing the oxygen fraction in the inhalation gas mixture from 21%(control) to 15%, 10% and 5% at every 5 minutes, and then reoxygenated with 60% oxygen. Mean arterial pressure, central venous pressure and mean pulmonary arterial pressure were measured directly using pressure transducers. Cardiac output was measured by the thermodilutional method. For analysis of blood gas, saturation and content, arterial and mixed venous blood were sampled via the femoral and pulmonary artery at the end of each hypoxic condition. The concentration of plasma catecholamines was determined by radioenzymatic assay. According to the exposure of graded hypoxia, not only did arterial and mixed venous oxygen tension decreased markedly at 10% and 5% oxygen, but also arterial and mixed venous oxygen saturation decreased significantly. An increased trend of the oxygen extraction ratio was seen during graded hypoxia. Cardiac output, mean arterial pressure and systemic vascular resistance were unchanged or increased slightly. Pulmonary arterial pressure(PAP) and pulmonary vascular resistance(PVR) were increased by 55%, 76% in 10% oxygen and by 82%, 95% in 5% oxygen, respectively(p<0.01). The concentrations of plasma norepinephrine, epinephrine and dopamine increased by 75%, 29%, 24% in 15% oxygen and by 382%, 350%, 49% in 5% oxygen. These data suggest that the sympathetic nervous system was activated to maintain homeostasis by modifying blood flow distribution to improve oxygen delivery to tissues by hypoxia, but hemodynamic changes might be blunted by high concentration of nitrous oxide except PAP and PVR. It would be suggested that hemodynamic changes might not be sensitive index during hypoxia induced by high concentration of nitrous oxide exposure.

• Proceedings of the KOSOMBE Conference
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• v.1995 no.11
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• pp.159-163
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• 1995

• Sleep Medicine and Psychophysiology
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• v.12 no.1
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• pp.68-71
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• 2005

We report a case of obstructive sleep apnea syndrome, which occurred primarily during the REM sleep stage. A 55-year-old female patient who complained of chronic insomnia on the initial visit turned out to have obstructive sleep apnea syndrome of a mild degree (respiratory disturbance index (RDI) of 13.8/hour, %time spent below 90% of SaO2=5.0%) on nocturnal polysomnography. Interestingly, apnea episodes and desaturations mainly occurred during REM sleep stage. And RDI and destaturations during REM sleep stage were found to be severe enough to classify as a severe degree of obstructive sleep apnea syndrome. These findings suggest that severe obstructive sleep apnea syndrome might be masked under the symptom of chronic insomnia and that apneas can be predominantly localized within REM sleep epochs. In terms of treatment, "REM sleep-dependent" apneas may call for different methods of treatment, especially REM sleep-specific pharmacological intervention.

• Progress in Medical Physics
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• v.7 no.1
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• pp.25-35
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• 1996

Optical measurements of turbid biological tissue have provided a means to study tissue metabolism, tissue blood perfusion and blood oxygenation non-invasively. We used the red light of 660nm and infrared of 880nm to measure the blood fractional volume and oxygen saturation of biological tissue. In vivo reflectance data were obtained the physiological change from the deep tissue in human subject. The data evaluation was assessed by examining the slopes of the plotter index for the changes in oxygen saturation and blood fraction volume. The index is the natural logarithm of the ratio of reflected light intensity from measured medium to reference intensity at each wavelength. According to the experimental results, oxygen index changes significantly in the muscle of calf during exercise.

• Proceedings of the Korea Information Processing Society Conference
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• 2015.10a
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• pp.578-579
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• 2015

Transmission and reflectance are two non-invasive techniques to perform pulse oximetry. This paper presents a design of reflectance-based pulse oximetry for watch-type wearable device, in which sensor and detector are located on the same surface of the body part. The basic principle of a pulse oximeter is based on the measurement of the red and infrared (IR) light absorption. Oxygenated blood has significant differences of light absorption characteristics than deoxygenated blood under red (660 nm) and infrared (940 nm) wavelength. Infrared is absorbed more by oxygenated hemoglobin than red. So the hardware implementation is included placing of the two LEDs (red and IR) with single photo-detector in the middle on the patient's wrist to get the corresponding pulsatile signals which are used to estimate the $SpO_2$.

• Proceedings of the Korean Society of Computer Information Conference
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• 2019.01a
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• pp.237-238
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• 2019

본 과제는 기존의 기술의 현황으로 건강 검진 검사 하는데 오랜 시간과 비용이 많이 소요된다. 그로 인해 저소득층이나 교통이 어려운 곳에 위치한 섬 마을 등에서는 진료가 굉장히 어렵고 부담이 된다. 스마트 건강검진 키트는 간단한 부착을 통해 바이탈을 한번에 측정이 가능하고 그 결과를 그래프화 하여 검사 결과를 일반인도 한 눈에 볼 수 있게하며 그리고 수치를 표시하여 문제가 있을 시 그 수치를 정상수치와 비교하여 블루투스를 통해 의사에게 보낼 수 있도록 목표를 설정하였다. 진료 전 맥파(PPGA), 혈중산소포화도(SpO2), 심전도(ECG), 체온 센서를 활용하여 바이탈 수치를 한번에 측정하고 수치화된 정보를 그래프화 시켜 나타내어 의사에게 결과를 수신하여 기초진단에 필요한 시간적 문제를 줄인다. 또한 기초 진단에 문제가 있을 경우 환자 개인에게도 수신하여 자신의 진료 당시 기초 진단 정보와 일반적인 경우와 비교할 수 있도록 활용할 수 있다.