• Proceedings of the Korean Society of Applied Pharmacology
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• 1992.05a
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• pp.59-59
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• 1992

간헐적 혈액투석 또는 지속적 복막투석 요법을 받고 있는 만성 신부전 환자에서 carumonam의 약동학적 변화를 분석하여 이 환자들에서 적절한 투여용법을 고안하고, 이들 특수 질환군에서의 임상시험모형을 도굴하고자 하였다. 혈액투석환자는 carumonam 1g을 20분간 지속 정주 후 약물의 분포기 종료가 예상되는 시간에 혈액투석을 4-5시간 시행하였으며, 혈액, 투석액, 뇨를 경시적으로 채취하였다. 지속적 복막투석 환자군에 있어서는 1일 3회(6, 6, 12시간) 복막 투석을 시행하는 환자를 대상으로 carumonam 1g을 정주하고 24시간동안 혈액 및 투석액, 뇨를 경시적으로 채취하였다. 혈액, 투석액 및 뇨중 carumonam의 농도는 HPLC방법으로 측정하였으며, 경시적인 혈장 carumonam 농도변화 및 투석에 따른 약물의 제거를 혈액 투석환자는 2 compartmental model, 복막투석환자에서는 bidirectional 2 compartmental model에 의해 그 약동학적 성상을 분석하였다.

• Proceedings of the Korean Society of Applied Pharmacology
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• 1994.04a
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• pp.333-333
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• 1994

목적 : 만성신부전환자에서 carumonam의 약동학적 특성을 검토하고, 동시에 투석에 의한 carumonam의 제거 양상을 분석하여 이들 환자에서 carumonam의 적절한 투여용량 및 용법을 고안하고자 하였다. 방법 : 혈액투석(HD) 또는 지속성 복막투석(CAPD)을 받고 있는 14명의 말기 신부전중 환자를 대상으로 하였다. HD환자에서는 carumonam 1 g을 20분간 지속정주하고 4시간 이후 혈액투석을 4 또는 5 시간 시행하였으며 투약 후 36시간까지 경시적으로 혈액 및 투석액을 채취하여 체액내 약물 농도를 측정하였다. CAPD환자는 1일 3회 (6.6, 12 시간) 투석액을 교환하는 환자를 대상으로 하였고 투석직후 carumonam 1g을 지속정주하고, 투약후 36시간 후까지 경시적으로 혈액 및 투석액을 채취하여 CAPD 환자에서 carumonam의 약동학적 특성을 검토하였다. 체내 동태는 HD의 경우 dialyser를 포함하는 2-compartmental model에 의한 분석을 시행하였고, CAPD를 시행받는 환자의 경우에는 체액과 투석액사이에 bidirectional clearance 개념을 도입한 모델을 이용하여 분석하였다.

• Journal of Digital Convergence
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• v.13 no.7
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• pp.269-282
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• 2015

This study is to define the hemodiafiltration treatment compliance indicators and discriminate standards for hemodiafiltration patients and development of hemodiafiltration treatment compliance measurement-convergent form. Date was collected from 300 on-line hemodiafiltration patients. To verify the hemodiafiltration treatment compliance indicators and discriminate standards, used construct validity and content validity by clinical professional group. Discriminant ability of 3 indicators-interdialysis weight gain rate(IWGR), serum phosphate level, rate of self change of total hemodiafiltration treatment time(SCR-HEFTT)- is 95.6%(wilks ramda=.256, p=.002). And hemodiafiltration treatment compliance measurement-convergent form has 91.7% discriminant accuracy. Hemodiafiltration treatment compliance is important that nurses can aware pre-stage of complication and give appropriate nursing intervention. Also this measurement can be used for foundation data of the nursing intervention development that prevent dialysis patient's complication.

• Journal of Industrial Convergence
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• v.22 no.2
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• pp.127-134
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• 2024

This study was attempted to understand the phenomenon in depth by exploring the food craving of hemodialysis patients experienced during hemodialysis. Participants selected seven adult patients diagnosed with end-stage renal failure and receiving hemodialysis treatment from medical institutions. he collected data were analyzed using a phenomenological analysis method. As a result of the analysis the food craving of hemodialysis patients was derived into two categories included craving experience in the cognitive domain craving experience in the emotional domain and five themes: 'Looking for foods that are water and watery as a result of thirst','Food thoughts come to mind all day as a result of a limited diet', 'Always hungry', 'Faced with appetizing situations every hour', 'experiencing negative emotions due to failure to control meals'. The results of this study which sheds light on food craving from the perspective of hemodialysis patients should improve the understanding of hemodialysis patients appetite control water restrictions and dietary compliance and allow them to understand the food craving attributes of hemodialysis patients and provide customized education optimized for that extent when applying dietary education and nursing interventions suitable for them.

• Journal of Digital Convergence
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• v.18 no.11
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• pp.433-441
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• 2020

The specific purpose was to determine the effect of walking on the body composition and hematological index of hemodialysis patients in order to confirm the relationship between activity and health level of hemodialysis patients. The research method is a cross-sectional descriptive survey conducted in hemodialysis patients.The subjects were 66 hemodialysis patients undergoing hemodialysis treatment in B city. As a result of the study, walking was decreased in hemodialysis patients, and there was a difference in hematological index according to walking, but there was no difference in body composition. As body weight increased, skeletal mass, body fat mass, body mass index, abdominal fat percentage, basal metabolism, and protein increased, but total cholesterol and high-density cholesterol decreased. This study proposes to expand the number of subjects of hemodialysis patients to investigate by adding nutritional intake in addition to walking, body composition and hematological index.

• Korean Journal of Psychosomatic Medicine
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• v.11 no.2
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• pp.170-181
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• 2003

Objectives: The purpose of this study was to evaluate the quality of life in hemodialysis patients and compare it with those of depression or anxiety patients. Methods: Quality of life in hemodialysis patients(n=33) and depression or anxiety patients(n=34) was evaluated. we performed Korean Version of WHO Quality of Life Scale Abbreviated Version(WHOQOL-BREF), Beck Depression Inventory(BDI), State-Trait Anxiety inventory(STAI) to both hemodialysis patients and depression or anxiety patients. Results: The WHOQOL mean scores showed no differences between hemodialysis patients and depression or anxiety patients. Among WHOQOL domains, psychological domain score of WHOQOL was significantly higher in hemodialysis patients than in depression or anxiety patients. Anxiety score of hemodialysis patients was significantly lower than that of depression or anxiety patients, while depression score showed no difference. Conclusion: These results show that psychological domain score of WHOQOL was higher and anxiety score was lower in hemodialysis patients than in depression or anxiety patients. However, there were no significant differences in total QOL and depression between hemodialysis patients and depression or anxiety patients, and the prevalences of depression and anxiety were higher in hemodialysis patients than those of general population. This suggest that hemodialysis patients need more specialized help for psychiatric problems.

• The Journal of the Korea Contents Association
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• v.17 no.8
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• pp.631-643
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• 2017

The purpose of this study is to examine factors affecting the life satisfaction of patients with hemodialysis in order to improve the quality of life for patients with hemodialysis. The subjects of this study are 168 patients who have undergone hemodialysis treatment in the hemodialysis rooms in D-city and C-providence. The data are collected between August 20th to September 5th, 2015. By using SAS 9.3 statistics program for data analysis, frequency, ${\chi}^2$-test, variance analysis and multiple regression analysis are conducted. Based on the analysis, it is found that family support(t=5.33, p<.001) and self-efficacy(t=3.52, p<.001) are statistically significant to the quality of life for male patients. Family support(t=2.58, p<.012) and adherence to self-care(t=4.08, p<.001) are statistically significant to the quality of life for female patients. With the study results, it suggests that nurses can help improve the affective and psychological stability of patients with hemodialysis by recognizing the factors affecting the life satisfaction of patients with hemodialysis by gender, developing and utilizing a nursing intervention.

• Journal of the Korean Data and Information Science Society
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• v.27 no.2
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• pp.487-498
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• 2016

The purpose of this study was to identify the effects of education for hemodialysis patient with a family caregiver on self-care practice and on blood biochemical parameters. A nonequivalent control group pretest and posttest design has been employed for analysis. Among hemodialysis patients in C university hospital located in Daegu, 56 subjects, 28 in experimental and 28 in control group, participated in the study from April to May in 2015. The experimental group whose family caregiver participated in education for hemodialysis patient reported significant differences in self-care practice (t=3.36, p=.001) and serum potassium level (t=2.78, p=.007) from the control group whose family caregiver did not participate. Considering positive effects of family education, we suggest education programs incorporating family caregivers be used as an effective nursing intervention.

• Proceedings of the KSCN Conference
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• 2004.05a
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• pp.416.1-416
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• 2004

본 연구는 투석치료를 받고 있는 만성 신부전환자의 영양소 섭취량과 이에 영향을 미치는 요인을 분석함으로써, 환자들의 영양상태를 개선하기 위한 자료를 제공하고자 실시하였다. 연구 대상자는 대구지역 대학병원에 내원하는 혈액투석 환자 51명과 복막투석환자 50명을 대상으로 직접면담법으로 자료를 수집하였다. 설문지 내용은 영양소 섭취량에 영향을 미치는 요인으로 일반적 특성, 기호도, 영양지식과 태도, 스트레스 자각 정도, 식습관, 식품섭취빈도조사 등이었다. 조사대상자의 신장질환 유병기간은 혈액투석 환자군은 55.8 $\pm$ 61.3개월, 복막투석 환자군은 68.6 $\pm$ 61.5개월이었다.(중략)

• Journal of Digital Convergence
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• v.10 no.5
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• pp.301-305
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• 2012

This study was performed to examine the relationship between fatigue and fatigue-regulation behavior in Hemodialysis(HD) patients. Methods: The subjects for this study were 107 patients on HD who were registered in a hospital in Seoul. The data were collected from August 2 to August 14, 2010. The collected data were analyzed by the SPSS WIN 12.0 program. Results: The mean score of fatigue was 77.1 which means their experience of high level fatigue. Frequency of the fatigue-regulation behavior and the mean of efficiency of the fatigue-regulation behavior was 8.8 and 22.8. Positive correlation was found between fatigue and fatigue-regulation behavior (r=.45, p=.000). Conclusion: It is considered that the study emphasizes for the healthcare providers to recognize fatigue as the important nursing issue for HD patients. And it is necessary to develop an evidence-based nursing intervention program for regulating fatigue in HD patients.