• Tuberculosis and Respiratory Diseases
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• v.49 no.4
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• pp.466-473
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• 2000

Background : Patients with locally advanced non-small cell lung cancer are often treated with radiation alone or in combination with chemotherapy. Both modalities have a potentially damaging effect on pulmonary function. In order to examine changes in the cardiopulmonary exercise function of patients with locally advanced non-small cell lung cancer before and after conventional radiotherapy, we conducted a prospective study involving patients with such cancer, that had received radiation therapy. Method : Resting pulmonary function test, thoracic radiographic finding and cardiopulmonary exercise test(CPET) were assessed prior to and 4 weeks following radiation therapy in 11 male patients with locally advanced non-small cell lung cancer. Patient with endobronchial mass were excluded. Results : The forces vital capacity (FVC), forced expiratory volume in 1 second ($FEV_1$ and maximal voluntary ventilation (MVV) did not decreased between before and 4 weeks after radiation but the diffusing capacity (DLCO) had decreased by 11% 4 weeks after radiation, which was not statistically significant. No changes in maximal oxygen consumption ($VO_2$max), carbon dioxide production ($VCO_2$), exercise time and work load were attributed to radiation therapy. Follow up cardiopulmonary exercise testing revealed unchanged cardiovascular function, ventilatory function and gas exchange. No difference in cardiopulmonary exercise test performance was observed between pre- and post-radiation. Conclusion : Cardiopulmonary exercise function did not decrease within the short-term after the radiation of patients with locally advanced non-small cell lung cancer.

• Journal of Korean Medicine Rehabilitation
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• v.18 no.2
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• pp.143-156
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• 2008

목적 : 갱년기 여성은 내장비만의 위험이 높으며 또한 심리적 변화를 겪는 시기이다. 갱년기 여성의 복부지방, 내장지방, 피하지방 및 이와 관련된 단순비만지표, 간울증, 스트레스, 우울, 자존감 등을 조사하여 갱년기 건강의 위협이 되는 신체 심리 인자를 알아보고자 이 연구를 시행하였다. 방법 : 병원공고를 통해 체질량지수 $23kg/m^2$ 이상 비흡연자인 만 45세 이상 55세 이하의 폐경 전후의 갱년기 여성 환자를 모집하여 2007년 8월 20일부터 24일까지 47명이 모집되었으며 이중 체질량지수 $25kg/m^2$ 이상이면서 복부 전산화 단층촬영 상 내장지방이 $100cm^2$ 이상인 20명의 단순비만지표, 체성분검사, 혈액검사, 복부 전산화 단층촬영 및 한방비만변증 (간울) 및 스트레스, 우울, 자존감 설문검사 결과의 상관성을 분석하였다. 본 연구는 경희대학교 동서신의학병원의 임상연구심사위원회의 승인을 받았다. 결과 : 1. 갱년기 비만여성에서 복부지방 면적, 피하지방 면적은 체질량지수, 체지방률, 허리둘레/신장비 등의 단순비만지표와 유의한 상관성을 보인 반면 (p < 0.01), 내장지방 면적은 단순비만지표와 상관성을 보이지 않았다. 2. 내장지방 면적은 사회 재적응 평가척도 (${\gamma}=0.577$, p < 0.01)와 유의한 상관성이 있었고, 선형회귀분석에서 유의한 결과를 나타냈다. $VAT(cm^2)=116.1+0.101{\times}(SRRS\;score)$ (${\gamma}^2=0.332$) 3. 피하지방은 식이태도 점수와, 총복부지방은 식이태도 점수 및 갱년기지수 중 혈관운동증상과 상관성이 있었다. 4. 간울증은 스트레스 반응척도, 우울지수, 갱년기지수 및 그 하부항목 중 혈관운동, 정신, 운동, 소화, 전신증상과 양의 상관성을, 자존감척도와는 음의 상관성을 나타냈으며, 내장지방과 직접적인 상관성을 보이지 않았다. 결론 : 간울증은 높은 스트레스, 우울, 갱년기 증상 및 낮은 자존감과 관련되는 것으로 나타났다. 폐경전후 비만여성에서 내장지방 면적은 간울증과 유의한 상관성을 보이지 않았으나, 생활 스트레스 사건이 많을수록 높아지는 것으로 나타나 갱년기 여성 내장비만에서 스트레스에 대한 대처가 중요할 것으로 사료된다. 추후 임상적 연계성 및 설문 보완에 대한 연구가 필요하리라 생각된다.

• Proceedings of the KSCN Conference
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• 2004.05a
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• pp.416.2-417
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• 2004

심혈관계 질환(CVD, Cardiovascular disease, CHD, Coronary heart disease)은 심장의 관상동맥에 염증반응과 혈전으로 인해 죽상경화중이 생겨 관상동맥이 좁아지거나 막히는 결과를 초래하는 질환으로 관상동맥질환, 고혈압, 말초혈관질환, 협심증, 심근경색증, 중풍 등이 포함된다. 심혈관계 질환의 위험인자들에는 서구화된 식생활, 유전, 나이, 성, 고혈압, 당뇨, 고지혈증, 비만, 운동부족, 스트레스, 흡연, 가족력 등이 있다. 그러나 식생활의 변화로 인한 심혈관계 질환과 생화학적 지표의 변화 및 관련 기전에 대한 연구는 거의 없었다.(중략)

• Progress in Medical Physics
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• v.23 no.3
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• pp.177-187
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• 2012

Magnetic resonance angiography (MRA) techniques are widely used in diagnosis of vascular disorders such as hemadostenosis and aneurism. Especially, phase contrast (PC) MRA technique, which is a typical non contrast-enhanced MRA technique, provides not only the anatomy of blood vessels but also flow velocity. In this study, we developed the 2- and 3-dimensional PC MRA pulse sequences for a low magnetic field MRI system. Vessel images were acquired using 2D and 3D PC MRA and the velocities of the blood flow were measured in the superior sagittal sinus, straight sinus and the confluence of the two. The 2D PC MRA provided the good quality of vascular images for large vessels but the poor quality for small ones. Although 3D PC MRA gave more improved visualization of small vessels than 2D PC MRA, the image quality was not enough to be used for diagnosis of the small vessels due to the low SNR and field homogeneity of the low field MRI system. The measured blood velocities were $25.46{\pm}0.73cm/sec$, $24.02{\pm}0.34cm/sec$ and $26.15{\pm}1.50cm/sec$ in the superior sagittal sinus, straight sinus and the confluence of the two, respectively, which showed good agreement with the previous experimental values. Thus, the developed PC MRA technique for low field MRI system is expected to provide the useful velocity information to diagnose the large brain vessels.

• 건강소식
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• v.26 no.12 s.289
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• pp.6-13
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• 2002

뇌졸중, 심근경색 등의 심혈관질환은 암과 더불어 우리나라의 주요 사망원인이다. 2002년 통계청이 발표한 2001년 사망원인통계를 보면 인구 10만명 당 암이 123.5명으로 1위, 뇌졸중 등 뇌혈관 질환이 73.8명으로 2위, 심장질환(허혈성 심장질환과 기타 심장질환 포함)이 34.2명으로 3위였다. 이러한 심혈관질환의 예방을 위해서는 평소 뇌혈관질환을 일으킬 수 있는 위험인자들을 잘 관리할 필요가 있다. 사망률이 높은 심혈관질환의 주요 위험요인은 성별, 연령 등 선천적으로 타고나는 고정요인과 흡연, 비만 등 본인의 노력에 따라 생활습관을 바꿔 위험을 낮출 수 있는 변동요인으로 나눌 수 있다. 성별, 연령은 바꿀수 없지만 생활습관은 바꿀 수 있다. 심혈관 질환 예방에 있어서 가장 중요한 것은 기본적인 건강관리 수칙인 금연, 과음하지 않기, 균형있는 올바른 식생활, 규칙적인 운동, 표준체중 유지하기, 정기검진 등이다.특히 심혈관 질환은 채소류와 식물성 단백질, 식물성 지방 등을 위주로 한 식이요법이 도움을 줄 수 있고 튼튼한 혈관을 가지기 위해서 질 좋은 단백질과 비타민ㆍ무기질을 충분히 섭취해야 하며 콜레스테롤의 배설을 돕기 위해 섬유소가 충분한 식사를 한다. 갑자기 추워진 날씨로 생명을 다투는 뇌졸중이나 협심증, 심근경색 등 심혈관 관련 질병이 발생하기 쉬운 겨울철이다. 행사가 많은 연말에 과음을 삼가며 금연하고, 평소 담백한 한식 위주의 식사, 꾸준한 운동 등으로 건강관리에 힘써서 치명적인 심혈관 질환에 미리미리 대비하도록 한다.

• Journal of Chest Surgery
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• v.31 no.2
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• pp.208-211
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• 1998

Reflex sympathetic dystrophy is an important clinical entity that is characterized by excessive or prolonged pain, vasomotor and other autonomic disturbances, delayed recovery of function, and trophic changes. This syndrome is among the most frequently encountered problems in clinical medicine, and proper diagnosis and therapy are critical. Accidental or surgical trauma or one of a variety of disease states may become a precipitating factor. Proper recognition and treatment result in rapid elimination of symptoms and complete recovery. A 56-years old male accidented total amputation of the proxomal part of the left index finger in May, 1996. Emergently, complete replantation procedure was successfully performed in the department of reconstructive surgery, medical center, Korea University. Afterward, he began to suffer from uncontrolled, prolonged pain in left index finger, proximally spreading pain to the left upper extremity and limited joint movement of the left shoulder. Although many treatments were used for this syndrom, not all of them were effective. Furthermore, the treatments which proved effective had detrimental side effects. However, thoracoscopic left thoracic sympathectomy was performed in our department. This therapy successfully relieved the pain and improved shoulder joint movement.

• Journal of the Korean Society of Food Science and Nutrition
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• v.32 no.8
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• pp.1370-1376
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• 2003

We investigated the effect of seatangle drink and seatangle extract on lipid oxidation, blood coagulation and intestinal movement in rats fed a hyperlipidemic diet. In the dietary hyperlipidemic induced group, the serum superoxide dismutase activity decreased and formation of hydroxy radical increased when compared to normal group, but these were controlled by seatangle drink treatment. The decreased of bleeding time and increased of tissue factor in the dietary hyperlipidemic rats were regulated by seatangle drink and seatangle extract, and especially the activity of tissue factor was remarkably decreased. Seatangle drink and seatangle extract were increased contraction on intestinal movement. Therefore, it can be concluded that seatangle drink or seatangle extract treatment depresses changing in absorption of gastrointestinal track in rats fed a hyperlipidemic diet.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.10 no.11
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• pp.3458-3464
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• 2009

This study was conducted to investigate the relationship between maximum oxygen uptake and its related factors including body measurement and vascular compliance. The subjects of our study were 43 males and 53 females aged 40 to 59 who were visited in military health center. The main results were that 1.the degree of obesity had significantly negative correlation to vascular compliance in male, and waist-hip ratio in female. 2. The degree of obesity, body mass index, waist-hip ratio and body fat percent had significantly negative correlation to maximum oxygen uptake in male, and waist-hip ratio & body fat percent in female. 3. Maximum heart rate had significantly positive correlation to maximum oxygen uptake in male, and vascular compliance & maximum heart rate in female. 4. In multiple regression analysis which maximum oxygen uptake was as dependent variable, body fat percent, vascular compliance and maximum heart rate were significant variables for both male and female. In conclusion, Maximum oxygen uptake of some rural people age 40 to 59 were affected by various factors such as body fat percent, vascular compliance, and maximum heart rate.

• The Journal of Korea Institute of Information, Electronics, and Communication Technology
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• v.16 no.3
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• pp.152-160
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• 2023

After the recent COVID-19 outbreak, more and more people are paying attention to health care. Many people feel uncomfortable in life due to muscle pain after sports or exercise as a hobby and often take a break from exercise. After exercising for a long time or exercising excessively, pain appears throughout the body within 24 to 48 hours after exercise. This pain is called delayed onset muscle soreness (DOMS). In this study, the effectiveness of the pain relief of delayed onset myalgia was verified by using a high-frequency pain therapy device that generates deep heat. EMG was measured before and after pain treatment at ordinary times, RMS values were obtained through analysis, statistical analysis was performed using the SPSS program, and it was judged to be statistically significant. In addition, statistical analysis of the RMS value between normal and after pain treatment was conducted to confirm that there was no significance, and to confirm how much it returned to normal after pain treatment. In addition, since the standards for pain are different for each person even if the size of the same pain is the same, the NRS questionnaire for the size of pain was conducted, and the size of pain felt by the subjects was analyzed using the SPSS program and statistical significance was obtained. Therefore, as a result of this study, the high-frequency pain therapy device generated deep heat in the pain area to raise the temperature, and expanded the arteries and capillaries to increase blood flow, thereby increasing blood circulation and metabolism, and alleviating the pain of delayed onset muscle pain.

• Journal of Chest Surgery
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• v.35 no.9
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• pp.688-691
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• 2002

Takayasu's arteritis is a chronic inflammatory disease of unknown cause. It predominantly affects the aortic arch and its branches. Concomitant involvement of coronary and renal arteries is a rare entity. In this report, we described successful treatment of a patient with Takayasu's arteritis associated with coronary and renal arteries stenosis. A 23-year-old woman was presented with chest pain on exertion. Angiographic studies demonstrated left main coronary, bilateral renal, and left subclavian arteries stenosis. She underwent angioplasty and stenting of bilateral renal artery. After one week, coronary artery bypass grafting using greater saphenous veins and aorto-subclavian bypass with PTFE vascular graft were done simultaneously. She was discharged on the 13th postoperative day without any complications.