• Title/Summary/Keyword: 허용 기준

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The Effectiveness of the Living Lab-based Elementary School Data Science Program (리빙랩 기반 초등학교 데이터 과학 프로그램의 효과성 분석)

  • Son, Jungmyoung;Kim, Taeyoung
    • Journal of The Korean Association of Information Education
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    • v.26 no.2
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    • pp.105-120
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    • 2022
  • In addition to the rapid changes in the times caused by the pandemic, the revision of the new curriculum coincides with the change in the proportion of the three elements of learners, society, and subjects that make up the curriculum. In particular, along with the proportion of 'social' in the curriculum, the scope of the word 'educational community' has increased, and the allowable range of curriculum restructuring centered on it has expanded. In order for the intended direction of education to be properly established in the new curriculum, various educational method studies are needed to cultivate newly emerged competencies and literacy. In this study, after selecting the contents and goals of the convergence curriculum based on various criteria for subject selection, the data science program was designed by reconstructing Living Lab's PDIE methodology. As an evaluation factor for this, we tried to analyze the effectiveness of 'creativity', 'problem-solving ability', 'communication ability', 'collaboration ability' among future competencies emphasized in the curriculum. As a result of the study, it was effective in improving creative and communication skills, and this study focuses on verifying the effectiveness of School Living Lab, suggesting the necessity of post-research that expands the application space of research and diversifies the role of educational community subjects.

The Meaning and the Legislative Suggestion about Data Manipulation of Pharmaceutical Companies in the Aspect of the Medicine Approval System (의약품 품목허가 제도에서 제약기업 자료조작의 의미와 입법 개선 방안-대법원 2008. 11. 13. 선고 2008두8628 판결을 중심으로-)

  • Park, Sungmin;Shin, Youngkee
    • The Korean Society of Law and Medicine
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    • v.22 no.4
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    • pp.59-88
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    • 2021
  • The National Assembly of the Republic of Korea recently enacted laws to fortify sanctions about data manipulation of pharmaceutical companies. The medicine approval system is the result of legislative efforts to prevent accidents that caused damages to patients' life and health. The medicine approval system is based on the trust that the data submitted by pharmaceutical companies is not manipulated. The Supreme Court of Korea clarified that strict standard shoud be required to secure the medicine safety in Supreme Court Decision 2008Du8628 decided November 13, 2008. We agree. This paper suggest legislation to weaken the economic incentives for pharmaceutical companies to choose data manipulation by minimizing the expected profit. In addition to revoking the marketing authorization of the medicine, the 'unfair' profits the pharmaceutical company has earned must be recovered. In addition, in order to increase the possibility to discover data manipulation, it is necessary to strengthen the review capacity and to activate the whistle-blowing.

Reinforcing Effect of Buildings Considering Load Distribution Characteristics of a Pre-compressed Micropile (선압축 보강마이크로파일의 하중분담 특성을 고려한 건물 보강효과에 대한 연구)

  • Lee, Kwang Hoon;Park, Yong Chan;Moon, Sung Jin;You, Kwang Ho
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.42 no.6
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    • pp.825-836
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    • 2022
  • Micropiles can be used to support additional load in extended building structures. However, their use brings about a risk of exceeding the bearing capacity of existing piles. In this study, pre-compression was applied to distribute the load of an existing building to micropiles, and an indoor loading test was performed to confirm the structural applicability of a wedge-type anchorage device designed to improve its capacity. According to the test results, the maximum strain of the anchorage device was 0.63 times that of the yield strain, and the amount of slip generated at the time of anchorage was 0.11 mm, satisfying structural standards. In addition, using MIDAS GTS, a geotechnical finite element analysis software, the effect of the size of the pre-compression, the thickness of the soil layer, and the ground conditions around the tip on the reaction force of the existing piles and micropiles were analyzed. From the numerical analysis, as the size of the pre-compression load increased, the reaction force of the existing pile decreased, resulting in a reduction rate of up to 36 %. In addition, as the soil layer increased by 5 m, the reduction rate decreased by 4 %, and when the ground condition at the tip of the micropile was weathered rock, the reduction rate increased by 14 % compared with that of weathered soil.

Withdrawal time study of lincomycin administered intramuscularly to olive flounder Paralichthys olivaceus, and in vitro efficacy evaluation against Gram-negative bacterial pathogens (넙치에서 lincomycin 근육투여에 따른 휴약기간 도출 및 병원성 그람음성 세균에 대한 약효 평가)

  • Eun Ha, Jeong;Keun-Taek, Kim;Dong Hun, Shin;Jun Sung, Bae;Kang Uk, Lee;Chae Won, Lee;Chan Yeong, Yang;Areum, Kim;Ji-Hoon, Lee;Su-Jin, Bak;Kwan Ha, Park
    • Journal of fish pathology
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    • v.35 no.2
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    • pp.195-203
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    • 2022
  • This study was performed to delineate pharmacokinetic residue characteristics of lincomycin (LM) in olive flounder at low water temperature (13℃), and to examine whether LM is effective against main Gram-negative pathogens. It was observed that the times for residue declined below the maximal residue limit (0.1 mg/kg) in the muscle was, respectively, 32, 33 and 55 days following 10, 20 and 40 mg/kg intramuscular LM injections. The in vitro MIC value of LM against Edwardsiella piscida was higher than 256 ㎍/mL and against Vibrio harveyi 32 ㎍/mL when examined with several clinical isolates. These results suggest that the withdrawal time of LM should be more than 30 days in consideration of the 10 mg/kg employed as the regular clinical dose. It was also found that LM administered to treat streptococosis in olive flounder is not likely to be effective against some pathogenic Gram-negative bacteria.

Instrumentation Management of the Deep Soft Ground with Dredged Clay Reclaimed in the Upper (준설점토가 상부에 매립된 대심도 연약지반 계측관리)

  • Jung, Na-Young;Kang, Seung-Chan;Kim, Tae-Hyung
    • Journal of the Korean Geotechnical Society
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    • v.38 no.12
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    • pp.67-78
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    • 2022
  • In this study, the measurement results of the coastal deep soft ground buried in the upper part of the dredged clay were analyzed and compared with the current specification standards. Based on the results, a suitable proposal was suggested for the selection, installation, data arrangement, and analysis of each instrument used in the deep soft ground improvement construction. The pore water pressure meter has a range of 1.5 times or more of the expected measurement range, considering the field conditions of the soft ground. The groundwater level meter installed in the horizontal drainage layer checks the change in the groundwater level during the embanking as well as the performance of the catchment well and the horizontal drainage layer. Therefore, it is important to manage so that the groundwater level exists inside the horizontal drainage layer during embanking. It is enough to install the inclinometer in the gravel layer below the soft ground or weathered rock with an N value of 40 or more for the deep soft ground. It seems desirable to install a screw type for differential settlement meter. However, the screw type should not settle due to its own weight. Considering that it is a dredged landfill where subsidence occurs significantly, it is sufficient to manage the tolerance of leveling at about 10 mm (L is the one-way distance (km)).

Performance Evaluation of Multi-Friction Dampers for Seismic Retrofitting of Structures (구조물 내진보강을 위한 다중 마찰댐퍼의 성능 평가)

  • Kim, Sung-Bae;Kwon, Hyung-O;Lee, Jong-Suk
    • Journal of the Korea institute for structural maintenance and inspection
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    • v.26 no.6
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    • pp.54-63
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    • 2022
  • This paper is a study on the friction damper, which is one of the seismic reinforcement devices for structures. This study developed a damper by replacing the internal friction material with ultra high molecular weight polyethylene (UHMWPE), a type of composite material. In addition, this study applied a multi-friction method in which the internal structure where frictional force is generated is laminated in several layers. To verify the performance of the developed multi-friction damper, this study performed a characteristic analysis test for the basic physical properties, wear characteristics, and disc springs of the material. As a result of the wear test, the mass reduction rate of UHMWPE was 0.003%, which showed the best performance among the friction materials based on composite materials. Regarding the disc spring, this study secured the design basic data from the finite element analysis and experimental test results. Moreover, to confirm the quality stability of the developed multi-friction damper, this study performed an seismic load test on the damping device and the friction force change according to the torque value. The quality performance test result showed a linear frictional force change according to the torque value adjustment. As a result of the seismic load test, the allowable error of the friction damper was less than 15%, which is the standard required by the design standards, so it satisfies the requirements for seismic reinforcement devices.

Pesticides, heavy metals, radioactive substances, and ash of Poria cocos distributed in Korea (국내 유통 복령(Poria cocos)의 농약, 중금속, 방사선물질 및 회분 함량 조사 연구)

  • Jang, Eun-Kyoung;Jang, Hye-Mi;Wi, Chang-Heun;Ban, Seung-Eon
    • Journal of Mushroom
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    • v.19 no.4
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    • pp.294-299
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    • 2021
  • The purpose of this study is to provide basic data on the safety of Poria cocos, a major Korean herbal medicine, and to establish tolerance levels for hazardous substances. Residual pesticides (321 types), heavy metals (7 types), radioactivity (3 types), and ash content were analyzed in 10 Poria cocos products distributed in Korea (5 domestic and 5 in China). Of the residual pesticides, cypermethrin was detected at 0.03 mg/kg in one domestic sample and was below the standard value. Of the heavy metals, the levels of Zn, Pb, Ni, Cu, Hg, and Cr were below the standard values in all samples. Hg was not detected in any sample. Cd was detected at 0.011 mg/kg in one Chinese sample. The radioactivity concentration was also below the MDA value in all P. cocos samples. The ash content was less than the standard value of 1.0% in all P. cocos samples. The findings indicate that P. cocos distributed in Korea is safe. However, because P. cocos is always exposed to harmful substances because of the nature of its cultivation in the soil, it seems necessary to establish systematic management standards for the entire production stage, such as cultivation, storage, and distribution.

A Research on the Residual Pesticide Content of Dried Agricultural Products from Ulsan (울산지역 건조농산물 가공품의 잔류농약 분석)

  • Kim, Dae-Kyo;Kim, Seon-Hwa;Kim, Su-Hui;Choi, Jae-Seon;Kim, Hui-jeong;Kim, Young-Min
    • Journal of Food Hygiene and Safety
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    • v.37 no.4
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    • pp.238-248
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    • 2022
  • This study was conducted to evaluate the safety of 208 types of residue pesticides on 150 dried agricultural products in Ulsan. The pesticide residues were detected using GC-MS/MS, LC-MS/MS, GC/ECD, GC/NPD, and LC/PDA. The detection rate was 19.3% (29 of 150 samples), and 28 types of pesticides were detected. Two of the 29 pesticide residues exceeded the maximum residue limit (MRL). Difenoconazole was detected in Ulleungdo aster, and chlorothalonil and chlorpyrifos were detected in chili pepper leaves. In the vegetable group, the frequency of pesticide residues was found to be the highest in dried leafy vegetables, followed by dried fruiting vegetables other than cucurbit vegetables, and then dried stalk and stem vegetables. The pesticide types detected in the commercial dried agricultural products were fungicide (60%), insecticide (23.8%), and acaricide (16.3%). In the validation study, the values of limit of detection (LOD), limit of quantitation (LOQ), coefficient of determination (R2), and recovery rate were in the range of 0.0001-0.0409 mg/kg, 0.0003-0.1241 mg/kg, 0.994-0.999, and 81.58-116.79%, respectively. The ratio of estimated daily intake (EDI)/acceptable daily intake (ADI) was 0.00002-0.31395%.

Appropriateness Evaluation of Train Vibration Evaluation Method Considering Vibration Levels of Retaining Wall Adjacent to Railway Tunnels (철도터널과 인접한 흙막이 가시설의 진동 수준을 고려한 열차진동 평가방법의 적정성 평가)

  • Donghee Woo;Yeongjin Lee;Yongjae Song;Kangil Lee
    • Journal of the Korean GEO-environmental Society
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    • v.24 no.10
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    • pp.5-13
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    • 2023
  • With the recent increase in development projects centered on urban areas, the construction of building structures is increasing in areas adjacent to the urban railway operation section. In this case, since ground vibration is generated by the train in operation and affects the adjacent structure, the building structure needs appropriate vibration reduction against train vibration generated at the adjacent location from the desing phase. However, the vibration levels calculated vary depending on the train vibration evaluation method, which means that the implementation of vibration reduction may vary depending on the train vibration evaluation method. Therefore, this study calculated the vibration level according to ground conditions, tunnel depth and separation distance between vibration sources and adjacent structures using numerical analysis and train vibration evaluation methods, and compared them to designning phase. And the appropriate separation distance between the tunnel and the adjacent structure was evaluated by comparing the vibration level with the allowable standards. As a result of the study, the Ungar and Bender evaluation method is evaluated as the most appropriate among the train vibration evaluation methods, and the appropriate separation distance between the tunnel and the adjacent structure is evaluated to be more than 4.5D.

A review on the previously performed hydraulic experiments of bank protection materials (기 수행된 호안재료 수리 검토 실험에 관한 고찰)

  • Chanjoo Lee;Myeonghwan Kim;Sungjung Kim;Muyoung Na
    • Proceedings of the Korea Water Resources Association Conference
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    • 2023.05a
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    • pp.297-297
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    • 2023
  • 최근 친수성, 경관, 생태계 보전 등을 위해 다양한 호안블록의 시공이 이루어지고 있어 호안블록의 수리적 안정성에 관한 관심이 증가하고 있다. 이러한 배경 하에 한국건설기술연구원 안동하천실험센터(이하 센터)에서는 2019년부터 실규모 수로를 이용하여 여러 건의 호안블록 실규모 수리검토 실험을 실시한 바 있다. 본 연구는 그간의 실험 결과를 종합적으로 고찰하고 수리 검토 실험의 현황과 한계점, 그리고 개선 방향을 제언하는데 그 목적이 있다. A1 수로(급경사수로, 하상경사 1/70)에서는 7건(21회), B1 수로(고유속수로, 하상경사 1/7)에서는 2건(6회)의 실험이 수행되었다. A1 수로 실험의 유량-소류력 관계는 1.0 m3/s에서 약 20 N/m2이며, 1.0 m3/s 증가당 약 11 N/m2이 증가하는 관계를 나타낸다. 7건의 실험 결과 30분 이상 지속된 최대 실험 유량은 6~7 m3/s 정도이며, 이는 A1 최대 공급 유량의 75 % 정도로서 안정적인 수준이라고 판단된다. 이 때의 최대 소류력은 75 N/m2 정도로 나타났다. B1 수로는 5 m/s 이상의 고유속 흐름을 발생시킬 수있으며, 2건의 실험 결과 0.5 m3/s에서 약 100 N/m2, 최대 4.5 m3/s에서 330 N/m2까지 소류력을 제공하여 실험을 수행한 바 있다. 따라서 A1, B1 수로를 통해 제공할 수 있는 소류력 범위는 10~330 N/m2이지만, 75~100 N/m2는 실험에서 제공된 바 없었다. 한편, 토양유실의 경우 수준측량에 의해 측정되는데, 대부분의 실험에서 Clopper의 토양손실 지수(1.27 cm) 미만의 결과가 발생하였다. 이는 시험체에 따라 여건이 다르기는 하지만, 수리 검토 실험시 3회 실험을 기본으로 하고 있고 호안재료의 침식이 기준 이하로 유지되면서 최대한의 성능을 발휘할 수 있는 소류력 조건을 얻으려는 실험 목적에 부합하도록 조절된 것으로 볼 수 있다. 이러한 실험 결과를 토대로 고려해볼 수 있는 개선 방향은 다음과 같다. 강성 재료가 아닌 연성 또는 친환경적 호안재료의 허용 소류력 범위를 보다 넓게 평가하기 위해 A1 수로가 제공하는 최대 소류력을 높일 필요가 있다. 이를 위해 기본 3회의 실험 외에 추가로 호안블록이 파괴되거나 토양유실 임계치를 초과할 수 있는 실험을 수행함으로써 각 제품의 한계 성능을 평가하는 것이 필요할 것으로 보인다.

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