• Tuberculosis and Respiratory Diseases
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• v.65 no.1
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• pp.7-14
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• 2008

Background: Residual pleural thickening (RPT) is the most frequent complication of tuberculous pleurisy (TP), and this can happen despite of administering adequate anti-tuberculous (TB) therapy. Yet there was no definite relation between RPT and other variables. The aim of this study was to examine matrix metalloproteinases (MMPs) and the inhibitors of metalloproteinases (TIMPs) and to identify the factors that can predict the occurrence of RPT. Methods: The patients with newly-detected pleural effusions were prospectively enrolled in this study from January 2004 to June 2005. The levels of MMP-1, -2, -8 and -9, and TIMP-1 and -2 were determined in the serum and pleural fluid by ELISA. The residual pleural thickness was measured at the completion of treatment and at the point of the final follow-up with the chest X-ray films. Results: The study included 39 patients with pleural fluid (PF). Twenty-three had tuberculous effusion, 7 had parapneumonic effusion, 7 had malignant effusion and 2 had transudates. For the 17 patients who completed the anti-TB treatment among the 23 patients with TP, 7 (41%) had RPT and 10 (59%) did not. The level of PF TIMP-1 in the patients with RPT ($41,405.9{\pm}9,737.3ng/mL$) was significantly higher than that of those patients without RPT ($29,134.9{\pm}8,801.8$) at the completion of treatment (p=0.032). In 13 patients who were followed-up until a mean of $8{\pm}5$ months after treatment, 2 (15%) had RPT and 11 (85%) did not. The level of PF TIMP-2 in the patients with RPT ($34.4{\pm}6.5ng/mL$) was lower than that of those patients without RPT ($44.4{\pm}15.5$) at the point of the final follow-up (p=0.038). Conclusion: The residual pleural thickening in TP might be related to the TIMP-1 and TIMP-2 levels in the pleural fluid.

• Food Science and Preservation
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• v.20 no.5
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• pp.668-683
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• 2013

In this study, we investigated the contents of total polyphenol (TP), total flavonoid, and absorbance at 475 nm ($OD_{475}$) which may produced in solid-fermented leaf of Smilax china L. by Aspergillus oryzae as a new functional components with reddish brown color, contents of water soluble substance (WSS), electron donating ability (EDA), Hunter $L^*$, $a^*$, $b^*$ values, sensory overall acceptability (OA) and also, the inhibitory activities (XOI and AOI) against partial purified xanthine oxidase (XO) and aldehyde oxidase (AO) from rabbit liver which were well known to relate the gout, and alcoholic liver disease, respectively in order to optimize water extraction using response surface methodology (RSM). All the $R^2$ values of the second-order polymonials ranged from 0.85 to 0.98, except for the EDA (0.69) and the XOI (0.78). However, the activities of the EDA and XOI were relatively high in the lower concentration of the fermented Smilax china L. leaf. The effects on the water extraction were highest in the concentration, among the dependent variables, and showed significant differences at the 1% level in the TP, TF and WSS contents and the $a^*$, $b^*$ and $OD_{475}$ values, but the OA showed significant differences at the 5% level. The optimal values of AOI, which was the most important functionality in the Smilax china L. that was predicted via RSM, were 59.48% at the 2.19% concentration, a $90.02^{\circ}C$ extraction temperature and a 4.03 minute extraction time ($R^2$: 0.93, p<0.007). The ranges of all the dependent variables of the optimal water extraction were 1.6~1.8% for the concentration, $83{\sim}93^{\circ}C$ for the temperature and 3.4~4.4 minutes for the extraction time; and the optimal water extraction conditions were a 1.7% concentration, an $88^{\circ}C$ extraction temperature and a 3.9-min extraction time.

• Korean Journal of Soil Science and Fertilizer
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• v.23 no.2
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• pp.87-93
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• 1990

A statistical model to predict soil temperature from the ambient meteorological factors including mean, maximum and minimum air temperatures, precipitation, wind speed and snow depth combined with Fourier time series expansion was developed with the data measured at the Suwon Meteorolical Service from 1979 to 1988. The stepwise elimination technique was used for statistical analysis. For the yearly oscillation model for soil temperature with 8 terms of Fourier expansion, the mean square error was decreased with soil depth showing 2.30 for the surface temperature, and 1.34-0.42 for 5 to 500-cm soil temperatures. The $r^2$ ranged from 0.913 to 0.988. The number of lag days of air temperature by remainder analysis was 0 day for the soil surface temperature, -1 day for 5 to 30-cm soil temperature, and -2 days for 50-cm soil temperature. The number of lag days for precipitaion, snow depth and wind speed was -1 day for the 0 to 10-cm soil temperatures, and -2 to -3 days for the 30 to 50-cm soil teperatures. For the statistical soil temperature prediction model combined with the yearly oscillation terms and meteorological factors as remainder terms considering the lag days obtained above, the mean square error was 1.64 for the soil surfac temperature, and ranged 1.34-0.42 for 5 to 500cm soil temperatures. The model test with 1978 data independent to model development resulted in good agreement with $r^2$ ranged 0.976 to 0.996. The magnitudes of coeffcicients implied that the soil depth where daily meteorological variables night affect soil temperature was 30 to 50 cm. In the models, solar radiation was not included as a independent variable ; however, in a seperated analysis on relationship between the difference(${\Delta}Tmxs$) of the maximum soil temperature and the maximum air temperature and solar radiation(Rs ; $J\;m^{-2}$) under a corn canopy showed linear relationship as $${\Delta}Tmxs=0.902+1.924{\times}10^{-3}$$ Rs for leaf area index lower than 2 $${\Delta}Tmxs=0.274+8.881{\times}10^{-4}$$ Rs for leaf area index higher than 2.

• Journal of the Korean Geotechnical Society
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• v.30 no.2
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• pp.53-64
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• 2014

This study sets it's face to define effects of the various loading periods in normal consolidation area on clay's compression and long-term consolidation characteristics through a laboratory test using homogeneous remolded clay. Moreover, by carrying out a long-term consolidation test which diversifies initial consolidation applicable to effective overburden loading in the various loading period. This study intended to suggest the method predicting the final settlement on the basis of loading periods by comparing and analyzing compression curve's characteristics according to loading weight of each stage and increase in loading period when carrying out the standard consolidation test. From the test results, the study shows that as of the soft clay's compression characteristics on the basis of various loading periods, preconsolidation load has a tendency to be decreased slightly as the loading period is getting more and more longer at each step after initial consolidation load puts on the remolded clay which is caused by secondary consolidation's increase in the latter part of each phase. And those effects have an weaker influence on compression index in normal consolidation area at the same time as secondary consolidation brought out quasi-overconsolidation and stabilization of clay's structure, have an influence re-compression index is increased in overconsolidation area on the other hand.

• Journal of the Korea institute for structural maintenance and inspection
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• v.19 no.2
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• pp.33-39
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• 2015

Recently, the event of slope failure has been occurring frequently due to rapid climate changes and broad development of infrastructures, and the research for establishment of monitoring and prevention system has been an attentive issue. The major influence factors of slope failure mechanism can be considered moisture and temperature in soil, and the slope failure can be monitored and predicted through the trend of moisture-temperature change. Therefore, the combined sensing technology for the continuous measurement of moisture-temperature with different soil depths is needed for the slope monitoring system. The various independent sensors for each item (i.e. temperature and moisture respectively) have been developed, however, the research for development of combined sensing system has been hardly carried out. In this study, the high-fidelity sensor combing temperature-moisture measurement by using the minimized current consuming temperature circuit and the microwave emission moisture sensor is developed and applied on the slope failure monitoring system. The feasibility of developed monitoring system is verified by various experimental approaches such as standard performance test, mockup test and long-term field test. As a result, the developed temperature-moisture combined measurement system is verified to be measuring and monitoring the temperature and moisture in soil accurately.

• Journal of Korea Port Economic Association
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• v.31 no.4
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• pp.1-15
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• 2015

During global recessions, such as the 2008 financial crisis, Korean shipping companies have been undergoing a liquidity crisis that is comparably worse than other shipping companies worldwide. One of the reasons behind this repetitive vicious cycle can be the lack of ability to foresee the future by analyzing and understanding the volatile shipping market. Traditionally, in order to assimilate the shipping market, larger Korean shipping companies have been purchasing market reports published by Europe-based research companies and shipping brokers, leading to a digital divide by company size. To resolve this issue, the Maritime Exchange Information Center (MEIC) has been publishing shipping market reports that include essential shipping information such as freight rates by different routes; commodity trends for iron ore, grain, and coal; ship-building trends for new-building, second-hand, and demolition markets; as well as bunker price and port congestion. This research was conducted to analyze the effectiveness of four variables-information usefulness, market reflection, information composition, and latest information-on information satisfaction. If the information satisfaction was found to be adequate, the analysis of actual proof was used to determine if the customers would be willing to purchase MEIC's report when it is chargeable. All the four variables were found to have positive effects on information satisfaction. In particular, latest information was found to directly affect the intention to purchase. Furthermore, high information satisfaction was related to the intention to purchase.

• Journal of the Korea Concrete Institute
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• v.15 no.1
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• pp.25-34
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• 2003

The degradation of reinforced concrete (RC) structures due to physical and chemical attacks has been a major issue in construction engineering. Deterioration of RC structures by chloride attack followed by reinforcement corrosion is one of the serious problems. An objective of this study is to develop a form of mathematical model of chloride ingress into concrete. In order to overcome some limits of the previous approaches, a chloride ingress model, consisting of chloride solution intrusion through the capillary pore and chloride ion diffusion through the pore water, was proposed. Moreover, the variability of chloride ion diffusivity due to the degree of hydration of cement, relative humidity in pore, exposure condition, and variation of chloride binding, was considered in the model. In order to verify the proposed model, the results predicted by the proposed model were compared with analysis results of Life-365, a computer program for predicting the service life of reinforced concrete structures exposed to chlorides. In conclusion, the proposed model would be promising to predict the chloride ion profile and to estimate the service life of RC structures.

• Journal of Korea Port Economic Association
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• v.24 no.4
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• pp.139-152
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• 2008

China's rapid growth of economy and developing logistics facilities such as sea and air ports can give the good effects to increase the trade and logistics cargo volumes within Pan Yellow Sea Economic Bloc which consists of Korea, China, Japan and Russia. These phenomenon also stimulate the development of the West Coastal Integrated Belt in South Korea. In the past 20th century, South Korea's advanced and developed areas were located on the Kyeong-Bu Axis, the straight line of Seoul and Busan. However, due to the china's effect, this axis is moving into the West Coast area between Incheon (Seoul) and Mokpo, which is closely located to China. In this aspect, sea ports located in West Coast of Korea have shown the steep increase in container and non-container cargo volumes. With regard to the changing environments in sea ports, this paper's aim is to investigate the developing potential of Gunsan (Saemangum) area located on mid of West Coast. As results, targeted area have shown the potential in terms of port network, supply chain management and transferring location for container cargoes. Moreover, for implementing the suitable roles, construction of New Saemangun port, closely located in Gunsan port, is needed to overcome the limitations of Gunsan port.

• Magazine of the Korea Concrete Institute
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• v.7 no.3
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• pp.187-198
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• 1995

This paper develops practical and reallstic reliabllity models and methods for the evaluation of system rehability and system rellabllity based ratlng of R.C box glrder bridge superstructures. The precise prediction of reberved carrying capacity of bridge as d system is extremely difficult especially when the brldges are highly redundant and slgnlficantly deter 1or;itcd or dainagetl. Thls papel proposes a nt2w approach for the evaluation of reseived system c,drrying capaaty of br~dges in terms ot equ~vdleiit system strength, which may b~ ddcflned as a brtdge system strength correipcmdlng tu the system rehability of the bridge. This cm be ticrAvcd from an Inverse process bami or1 the con~ept of FOSM(F1rst Order Second Moment) form of system reliabihty index. The sf rength llmt state models for K C box girder br~dges suggested In the paper dre based on the basi~ bending and shear strength And thc system reliatxllty pro,~lerri of box gritier super structure 1s formuldted as parallel serles models obtalncd f ~ o m thc FMA(Fdilure blode Rp proath) based on major failure mc>clmusrns or c~itlcal fdure ,>tatcs of each nuder .WOSM(Ad-vanced First Order Second Moment) and IST(1mportance Sampling Technique) simulation algorithm are used for the reliability analysis of the proposed models.

• Journal of Life Science
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• v.24 no.2
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• pp.167-172
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• 2014

Optimal conditions for extraction of bakkenolide B from Petasites japonicus leaves were determined by using response surface methodology. A second-order Box-Behnken design representing three extraction temperatures (80, 100, $120^{\circ}C$), three extraction times (30, 45, 60 min), and three solvent pH's (5, 7, 9) was executed. The efficiency of the extraction conditions was defined using the ${\beta}$-hexosamidase assay by comparing both the bakkenolide B content and its anti-allergic activity expressed as extract inhibition on degranulation. The response surface plot described for the bakkenolide B content showed that the maximum content was predicted as 121.6 ${\mu}g/g$ with extraction conditions of $127.1^{\circ}C$, 46.6 min, and pH 7.7. Extraction temperature and time were important factors in determining bakkenolide B content. Using regression analysis, correlation between the inhibition effect of mast cell degranulation and bakkenolide B content was found to be low.