• The Hankook-Saengyark Bo
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• no.112
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• pp.3-3
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• 1986

생약재의 생산및 판로대책 확대추진 - 의약품수출 행정지원 강화(보사부 신약 독점생산기간 연장) - 한방의보 전국확대 확정(내년3월내 실시 2천9백여 요양기관 지정)

• The Hankook-Saengyark Bo
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• no.256
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• pp.2-2
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• 2003

중국산 황기 4,862kg 국내산으로 위장판매 적발 - 안동시 노하동 한방생약 상가 조성 - 평창군, 희귀약용식물 직불제 실시(황기 만삼 하수오 토천궁 등 10종) - '사스'덕 홍삼 수출 활기

• The Hankook-Saengyark Bo
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• no.252
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• pp.6-6
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• 2002

연(蓮)잎 '항암차' 개발('백련차' 특허출원, 새로운 농가소득원 기대) - '우수한 한방 간염치료제 개발'(베트남 하노이 국영청년병원 의료팀) - 쑥 발효주 '천주' 화제(억만장자 영농조합 선봬)

• Journal of Korean Medicine Rehabilitation
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• v.34 no.2
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• pp.149-164
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• 2024

Objectives This study aimed to develop Korean medicine clinical practice guidelines for myofascial pain syndrome that can actually be applied clinically. Methods A text message containing a link to an online survey was sent to 26,987 Korean medicine doctors registered with the association of Korean medicine. The survey period was from December 29, 2023 to January 19, 2024. Results There were 2,762 Korean medicine doctors who responded to an online survey over a three-week period. Awareness of the standard clinical practice guidelines of Korean medicine was 74.5%, and utilization was 35.8%. The most frequently used diagnostic tool was a numerical evaluation tool, the treatment tool was acupuncture, and the prognosis management guidance was lifestyle guidance. Conclusions If standard Korean medicine clinical practice guidelines for myofascial pain syndrome are developed based on the results of this survey, guidelines that are highly usable in clinical settings will be developed.

• The Journal of Korean Obstetrics and Gynecology
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• v.20 no.4
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• pp.56-73
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• 2007

Purpose: 이 실험은 골다공증의 치료약물로 자하거의 골질재흡수 억제효과를 검토하기 위하여 설계되었다. Methods: 자하거의 골질재흡수 효과를 확인하기 위하여 생쥐의 두개골 골모세포를 이용하여 Cyclooxygenase-1(COX-1), COX-2, $TGF-{\beta}$, $L-1{\beta}$, $TNF-{\alpha}$, IL-6, prostaglandin E2등의 활성화 정도를 측정하였으며, 골조직의 미세구조적 변화를 확인하였다. Results: 자하거는 $IL-1{\beta}$, $TNF-{\alpha}$, IL-6 또는 그 세가지의 조합에 의하여 유발된 PGE2의 생성 뿐만 아니라 COX-2 mRNA 수치도 감소시켰으나 COX-1 mRNA 수치에는 영향을 주지 않았다. 이로써 자하거는 시험관내에서 그리고 생체내에서 펩티드의 인산화를 억제함으로써 골의 재흡수를 저해하였다. 그리고 자하거는 생쥐에서 $IL-1{\beta}$에 의해 유발된 고칼슘혈증을 감소시켰고, 골의 재흡수를 저해하는 경로를 통하여 골에 대한 보호효과를 보여줌으로써 조기에 난소 절제한 쥐에서 골질감소와 미세구조적 변화를 부분적으로 방지하였다. 이러한 결과는 PGE2 생성에 대한 $IL-1{\beta}$, $TNF-{\alpha}$, IL-6사이의 상승효과는 COX-2의 유전자 발현이 증가한 결과이며 이러한 tyrosine kinase가 생쥐의 두개골 골모세포에서 COX-2의 신호전달에 관계한다는 것을 보여준다. Conclusion: 자하거가 생쥐의 두개골 골모세포에서 여러 신호전달물질의 활성화를 통하여 골질재흡수를 저해하는 특성을 확인함으로써 앞으로 골다공증의 예방과 치료에 대한 추가적인 임상연구가 필요할 것으로 사료된다.

• Food Industry And Nutrition
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• v.7 no.1
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• pp.40-44
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• 2002

본 연구는 한방에서 여러 가지 기능성을 주목받고 있는 호박을 주원료로 하고 8가지 한방 생약재를 부재료로 첨가해 이것이 마우스의 혈액 성상 중 적혈구수와 hemoglobin에 어떤 영향을 미치는지 알아보기 위해 진행되었다. 실험은 부재료로 첨가되는 한방생 약재 의 종류와 1회 복용량에 따라9가지 그룹으로 나누어 진행되었으며 먼저 마우스에게서 출혈을 유도한 후 호박 및 한방생 약재 추출물을 먹인 대조군과 비교해 출혈 전으로 회복되는 정도를 살펴보았다. 그 결과 적혈구의 경우9가지 실험구 모두가 대조구에 비해서 유의적으로 적혈구 수가 증가하였다 첨가된 부재료의 수를 줄인 A와 B그룹보다 8가지 한방생약재를 모두 부재료로 첨가한 C그룹에서 가장 높은 증가효과를 보여 주었다. Hemoglobin의 경우에도 9가지 실험구 모두가 대조군에 비해 유의성있는 증가효과를 보여주었다 Hemoglobin도 적혈구와 마찬가지로 A와 B그룹보다 8가지 한방생약재를 모두 첨가한 C그룹에서 회복효과가 가장 우수하였다 적혈구와 hemoglobin모두 1회 복용량보다 첨가되는 한방생약재의 종류에 따라 회복효과가 더 큰 것으로 생각된다.

• Journal of Korean Traditional Oncology
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• v.23 no.2
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• pp.11-25
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• 2018

Objective: The purpose of this study is to report the case of a patient with non-small cell lung cancer (NSCLC) with Programmed cell death protein 1 (PD-1) mutation treated by Integrative Medicine Therapy (IMT). Methods: A patient with metastatic NSCLC received pembrolizumab 200mg intravenously for every 3 weeks from July 2017. Repeat cycle every 3 weeks since July 2017. The patient has been treated with Integrative Medicine Therapy (IMT) since December 2016. The tumor size was measured by computed tomography (CT) and magnetic resonance imaging(MRI). Adverse events were evaluated by the National Cancer Institute Common Terminology Criteria for Adverse Events (NCI-CTCAE), version 5.0. Results: After combined treatment, the extent of proximal portion of primary tumor in the left lower lobe was decreased and disease status was stable radiologically. No evidence of newly developed metastatic lesions in the brain since May 2017. The patient did not experience any adverse event according to NCI-CTCAE ver. 5.0. Conclusion: This case study suggests that Integrative Medicine Therapy (IMT) may contribute to tumor response, in conjunction with Pembrolizumab on the treatment of patients with NSCLC.

• The Journal of Internal Korean Medicine
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• v.43 no.6
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• pp.1274-1288
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• 2022

Objectives: The study investigated the effect of Korean medicine treatment on a hemiplegic patient with conscious and cognitive disorders due to hemorrhagic transformation after interventional reperfusion therapy of anterior circulation infarction. Case presentation: The patient was treated with acupuncture, moxibustion, cupping, and herbal medicine in combination with Western medicine and physical therapy. The effects on clinical symptoms were evaluated using the Manual Muscle Test (MMT), Glasgow Coma Scale (GCS), Korean Mini-Mental State Examination (K-MMSE), Korean Nursing Delirium Screening Scale (Korean Nu-DESC), and Modified Bathel Index (MBI). After the treatment, the MMT grade increased from Gr.0-1 to Gr.0-3, the GCS score increased from 10 to 15, the K-MMSE score increased from 8 to 15, the Korean Nu-DESC score decreased from 3 to 1, night delirium disappeared, and the MBI score increased from 13 to 26. Conclusions: Complex Korean medicine treatments were effective for improving the clinical symptoms of hemorrhagic transformation after interventional reperfusion therapy for anterior circulation infarction in a patient with hemiplegia and conscious and cognitive disorders. However, further studies are needed.

• Journal of Korean Medicine Rehabilitation
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• v.34 no.3
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• pp.107-117
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• 2024

The objective of this study is to report the clinical effects of applying an integrated rehabilitation protocol to four patients with traumatic cervical spinal cord injuries. The treatments applied included acupuncture, cupping and moxibustion, chuna manual therapy, functional electrical stimulation, and other physical therapies. The evaluation methods included American Spinal Injury Association Impairment Scale, functional independence measure (FIM), modified Barthel index (MBI), numeric rating scale (NRS) and other scales. All patients presented marked improvements in FIM, MBI, NRS and other scales, along with increased muscle strength in the manual muscle test. The application of our protocol resulted in clear clinical benefits and enhanced the recovery and quality of life for the patients in this study.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.16 no.4
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• pp.2726-2736
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• 2015

This study aimed to investigate the determinants of patients satisfaction and intent to revisit oriental medical hospitals. The level of overall patient satisfaction was used as an intervening variable and the level of intent to revisit was used as a dependent variable. The sample used in this study consisted of 578 patients from 3 oriental medical hospitals located in Chungnam Province. Data were collected from October 2014 to December 2014 with a structured and self-administrated questionnaire and analysed using path analysis. The results of the study indicate that oriental medical hospitals should make an effort to improve the overall satisfaction of patients, in the case of outpatient, especially focusing on the doctors' service and medical procedure, and in the case of inpatient, especially focusing on the facilities convenience, medical price and hospital ward life which will lead to high level of intent to revisit of patients.