• Korean Journal of Food Science and Technology
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• v.29 no.1
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• pp.167-172
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• 1997

Effect of combined preparation (DWP715) containing Alaska pollack extract, maltol, ascorbic acid and nicotinamide on decreasing of blood alcohol was evaluated in human blood. Treatment of DWP715 prior to administration of 25% alcohol (100 mL) decreased alcohol concentration in blood and showed significant difference after 2 hours. The pharmacokinetic parameters such as area under the concentration-time curve (AUC), $C_{max},\;T_{max}\;and\;T_{1/2}$ were also decreased and delayed when compared with control values. Effects of DWP715 on anti-fatigue and anti-oxidation activities were also studied in the restraint stress model using various parameters (GOT, GPT, LDH values and organ weights) on mild condition and examined through the content of lipid peroxide induced by 2% $CCl_4$ in mouse livers. While GPT level, thymus and adrenal weight were not influenced by DWP715 dosing, LDH, GOT level and spleen weight used as a parameter against fatigue and stress states were recovered almost to the nomal level. Furthermore, lipid peroxidation due to $CCl_4$ was significantly inhibited by DWP715 treatment. These results suggest that DWP715 seems to metabolize the blood alcohol rapidly and to restore the damaged liver and fatigue conditions which was caused by alcohol metabolism to normal condition.

• Journal of Dental Rehabilitation and Applied Science
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• v.28 no.1
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• pp.57-66
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• 2012

The purpose of this study was to evaluate the relation between intentionally induced internal stress and cyclic fatigue failure of ProTaper Universal. ProTaper Universal (Dentsply Maillefer) S1, S2, F1, F2, F3, F4 and F5 (25 mm length) were used in this study. To give the internal stress, the ProTaper Universal were put into the .02 taper Endo-Training-Bloc (Dentsply Maillefer) until auto-stop by torque controlled motor. The rotation speed was 300 rpm and torque value was 1.0 Ncm. ProTaper Universal were grouped by the induced number of internal stress and randomly distributed among one control group and three experimental groups (n=10). The four groups were Stress 0 (control), Stress 1, Stress 2 and Stress 3. These instruments were rotated until separation. For cyclic fatigue measurement, inclined plane was used and time for separation was recorded. It was statistically analyzed using two-way ANOVA and Duncan post-hoc test at 95% confidential level. In all ProTaper Universal, there was statistically significant decrease on time for separation in Stress 3. In F2 and F3, there were statistically significant difference between control group and all experimental groups. And in F4 and F5, Stress 2 and 3 groups showed significantly lower cyclic fatigue resistance from Stress 0 group. In the limitation of this study, cyclic fatigue failure of ProTaper Universal is influenced by accumulated internal stress.

• Journal of Oral Medicine and Pain
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• v.32 no.3
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• pp.319-328
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• 2007

The purpose of this study was to quantitatively assess treatment effect of physical therapy on experimentally-induced masseter muscle fatigue by two parameters of muscle stiffness and elasticity. Three physical therapeutic modalities inducing electroacupunture stimulation therapy(EAST), Microwave diathermy and low-level laser therapy(LLLT) were compared. 10 healthy volunteers with normal occlusion (mean age of $26.3{\pm}1.16$ years, M:F=1:1) were participated in this study. All subjects were asked to chew gum on the right side until they felt pain(more and VAS 5 (0 to 10)) and their masseter muscles were examined with a tactile sensor in order to evaluate changes of stiffness and elasticity according to gum chewing and three physical therapeutic modalities. Subjective discomfort or pain was self-estimated by VAS as well. Unilateral gum chewing increased stiffness and decreased elasticity only on the chewing side but VAS increased on the both sides(p<0.05). EAST or Microwave diathermy greatly decreased stiffness and VAS and increased elasticity(p<0.05) but LLLT did not exhibit significant difference. From the results of this study, it is concluded that both EAST and Microwave diathermy have favorable effect on stiffness and elasticity of muscles and pain relief while effect of LLLT is not reliable. In addition, experimental unilateral gum chewing compromises stiffness and elasticity of masseter muscles only the chewing side while subjective discomfort or pain can be felt on the both sides.

• Journal of Life Science
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• v.16 no.7 s.80
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• pp.1090-1096
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• 2006

The purpose of this study was to investigate the effects of p. Linteus and C. militaris supplement on lactate, phosphorous, ammonia, MDA(malondialdehyde), GPX(glutathione peroxidase) and TAS(total antioxidant status) following $VO_{2max}$, and 85% $VO_{2max}$ exercise. The 15 male college students were divided into three groups: 5 P. liteus supplied(PL), 5 C. militaris supplied(CM), and 5 placebos supplied(PB) and compared the differences between supplement before and after. Obtained results were as follows: In the exercise performance time, there were no differences in PL, CM and PB groups. Regular supplement of P. linteus or C. militaris partially reduces fatigue induction factors. Also, P. linteus or C. militaris supplement decreases MDA, increases GPX and TAS. Therefore, it can be concluded that P. linteus or C. militaris supplement not only have a pharmacological effect for clinical treatment, but also have a maintenance effects on the tissue oxidant-antioxidant system after exercise.

• Journal of Life Science
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• v.25 no.11
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• pp.1324-1330
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• 2015

The present study was performed to analyze and review the physical and immune responses to overtraining syndrome in humans. Overreaching refers to the initial phage of overtraining syndrome and has been known as a physical fatigue which is mainly from metabolic imbalance. It has been known that overtraining also results in a loss of adaptability which may lead to an attenuation of exercise performance, sleeping disorder, central fatigue, neurohormonal changes, difficulty recovery to physical stress, and immunological changes. Additionally, overtraining syndrome is characterized by persistent fatigue, poor performance in sport due to the prolonged and strenuous physical training. Also, previous studies reported that endurance athletes experienced a high incidence of URTI during intense training and the post training. And also, high-performance athletes reported that suppression of cell mediated and anti-body mediated immune function. NK cell numbers were also reduced in the period of overtraining syndrome. Major components of prevention and treatment for the overtraining syndrome are screening, education, and detraining. Furthermore, the combination of these prevention and treatment strategies will be much helpful. Therefore, the current review will be helpful for athletes and individuals who are at the risk of overtraining syndrome.

• The Korean Journal of Food And Nutrition
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• v.26 no.3
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• pp.485-491
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• 2013

Rhodiola spp. and red ginseng have been used for food and medicinal applications in disease chemoprevention in many Asian countries. Increased oxidative stress by reactive oxygen species (ROS) has been proposed to be a major cause of muscle fatigue. The present study was designed to investigate the protective effects of a fermented hot-water extract mixture from Rhodiola sachalinensis and red ginseng (MFR) on cell damage and the antioxidant enzyme system in $H_2O_2$-induced oxidative stress in skeletal muscle cells. C2C12 myoblasts were treated with various concentrations of NFR (non-fermented Rhodiola sachalinensis extract), FR (fermented hot-water extract from Rhodiola sachalinensis) and MFR for up to 5 days after the standard induction of differentiation, followed by semi-quantitative RT-PCR. MFR treatment dose-dependently protected oxidative damage of C2C12 cells. The treatment with MFR also enhanced mRNA expressions of MyoD, Cu/Zn SOD, Mn-SOD and GPX up to 16%. These results indicate that MFR exerts an anti-oxidative effect through a mechanism (s) that may involve the up-regulation of antioxidant enzymes, which may be important for the cellular redox environment in muscle cells.

• Journal of the Korean Institute of Landscape Architecture
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• v.41 no.4
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• pp.68-76
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• 2013

Effortful directed attention becomes fatigued if it is demanded by environment. Kaplan and Kaplan's Attention Restoration Theory (ART) proposes that the fatigued directed attention can be restored by a restorative landscape. The four restorative components are being away, fascination, extent, and compatibility. The restorative effect of landscape has been mainly investigated in terms of nature vs. urban dichotomy, although ART acknowledges that various types of landscapes can induce restorative effect. The purpose of this study is to examine whether sense of place of landscape has an influence on the restorative effect, and how the effect relates to the visiting experience. This study was performed in An-Ap-Ji with 200 Korean visitors who participated in the questionnaire survey. Hartig et al.'s PRS (Perceived Restorativeness Scale) was used as the research instrument to measure the restorative quality. The Analysis results are summarized as: 1) PRS was a very reliable measurement for Koreans' assessment of traditional landscape. Especially, the factor analysis produced four restorative components which fully supported ART. 2) The sense of place of landscape was found to have a positive influence on the restorative effect. 3) Landscape beauty was also discovered to be influential in the restoration even though the effect of beauty was lower than that of the sense of place. 4) Among the four restorative components, three components (fascination, escape, compatibility) influenced both visiting satisfaction and revisit intention, where the order of the relevant importance was fascination, escape, and compatibility. Based on the results, it was suggested that PRS should be used in landscape restoration research in Korea in order to re-examine its' reliability. It was also proposed that more research should be directed to investigate the relationship between the sense of place and the restorative effect of landscape.

• Journal of Korea Entertainment Industry Association
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• v.15 no.5
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• pp.175-188
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• 2021

The purpose of this study was to grasp the influence of mental health upon the lifelong drinking experience in adolescents of non-capital area and capital area through using the 2019 Youth Health Behavior Survey Data. The research subjects included total 57,303 adolescents who participated in the survey among 60,100 adolescents at totally 800 schools with 400 middle schools and 400 high schools. Out of these, 29,384 middle school students and 27,919 high school students were selected. As a result of the research, the mental health that has significant influence upon the lifelong drinking and smoking experience in case of non-capital area appeared to be significant in the perceived subjective health (p<.01), cognitive stress(p<.001), relief from fatigue(p<.001), sadness & despair experience(p<.001), suicide ideation(p<.001), suicide plan(p<.01), and suicide attempt(p<.001). In case of capital area, the mental health of having a significant impact on the lifelong drinking and smoking experience was indicated to be significant in cognitive stress(p<.01), relief from fatigue(p<.001), sadness & despair experience(p<.001), suicide ideation(p<.001), and suicide attempt(p<.001). Based on this outcome, adolescents' drinking problem has influence upon mental health characteristic. Hence, an effort is needed for developing the intervention & education program aiming at the more effective youth drinking prevention through establishing direction and revaluing education program in consideration of mental health factors by region in adolescents of capital area and non-capital area.

• YAKHAK HOEJI
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• v.57 no.5
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• pp.348-356
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• 2013

The present study investigated the effects of Hovenia Dulcis (HD) fruit extract powder on the improvement of physical activity, especially exercise capacity. Forty mice were divided into 4 groups including normal controls, negative controls, 100 (HD-100) and 200 (HD-200) mg/kg HD fruit extract powder groups for 5-times exercises using treadmill. Normal control did not performed treadmill running but others did 5-times for 10 days. HD fruit extract powders were administrated orally one-times per day for 10 days before treadmill exercise and normal and negative controls were fed with excipient water. After 5-times exercise, blood biochemical analysis showed that aspartate aminotransferase (AST), lactate dehydrogenase (LDH) and creatine phosphokinase (CK) activities and blood lactate concentration were statistically increased in negative controls than in normal controls. They were decreased in HD fruit extract powder groups, compared with negative controls. These results were considered as the effects of HD fruit extract powders on reduced tissue damages during exercise. Other measured indices did not reveal remarkable differences. All together, these results suggest that HD fruit extract powders may enhance the exercise performance by recovering the exercise-fatigue via blood lactate concentration by reducing blood LDH activity and via reduction of blood CK and AST activity.

• Journal of the Korea Convergence Society
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• v.6 no.3
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• pp.29-36
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• 2015

In order to have market competitiveness in the area of massage chair in domestic, it is necessary to establish a tactical promotion plan in terms of developing new technology and rethinking competitiveness. So, this research addresses four things, The first is to report an analysis that is for external environment changes and competitors the current situation through surveying the market trends of massage chair. The second is current technology of massage chair through surveying current technical trends of massage chair. In the basis of the surveying, the third is to establish alternative future technology for the chair. Finally, the last is to establish a counter-plan by analysing internal status and competitive power of each enterprise. On the basis of four things above, the future promote strategy and subject are proposed in this paper by producing the four strategic subjects.