• Proceedings of the Korea Contents Association Conference
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• 2009.05a
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• pp.306-311
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• 2009

We initially obtained human diseases-related proteins dataset from the OMIM and the SWISS PROT and then constructed disease-related protein-protein interaction network. The protein network contains 40 hub proteins such as CALM1, ACTB and ABL2. The protein network can be derived the map of the relationship between different disease proteins, denoted disease interaction network. We demonstrate that the associations between diseases are directly correlated to their underlying protein-protein interaction networks. From constructed the disease-protein bipartite network, we derived 38 diseasomal proteins, including APP, ABL1 and STAT1. We previously demonstrated that hub proteins in the network tend to be diseasomal proteins in the disease-related protein sub-networks. However, we found that 18% hubs are only diseasomal proteins in the whole disease network. At this point, we could not elucidate difference in the hub-diseasomal proteins tendency between sub0network and whole network. In spite of we still have unsolved problems, our results elucidate that the discovery of protein interaction networks assigned by diseases will provide insight into the underlying molecular mechanisms and biological processes in complex human disease system.

• KIPS Transactions on Software and Data Engineering
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• v.7 no.10
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• pp.387-396
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• 2018

Stock price prediction has been a difficult problem to solve. There have been many studies to predict stock price scientifically, but it is still impossible to predict the exact price. Recently, a variety of types of cryptocurrency has been developed, beginning with Bitcoin, which is technically implemented as the concept of distributed ledger. Various approaches have been attempted to predict the price of cryptocurrency. Especially, it is various from attempts to stock prediction techniques in traditional stock market, to attempts to apply deep learning and reinforcement learning. Since the market for cryptocurrency has many new features that are not present in the existing traditional stock market, there is a growing demand for new analytical techniques suitable for the cryptocurrency market. In this study, we first collect and process seven cryptocurrency price data through Bithumb's API. Then, we use the gradient boosting model, which is a data-driven learning based machine learning model, and let the model learn the price data change of cryptocurrency. We also find the most optimal model parameters in the verification step, and finally evaluate the prediction performance of the cryptocurrency price trends.

• Journal of the Korean School Mathematics Society
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• v.22 no.3
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• pp.329-350
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• 2019

Productive struggle is a student's persevering effort to understand mathematical concepts and solve challenging problems that are not easily solved, but the problem can lead to curiosity. Productive struggle is a key component of students' learning mathematics with a conceptual understanding, and supporting it in learning mathematics is one of the most effective mathematics teaching practices. In comparison to research on students' productive struggles, there is little research on preservice mathematics teachers' productive struggles. Thus, this study focused on the productive struggles that preservice mathematics teachers face in solving a non-routine mathematics problem. Polya's four-step problem-solving process was used to analyze the collected data. Examples of preservice teachers' productive struggles were analyzed in terms of each stage of the problem-solving process. The analysis showed that limited prior knowledge of the preservice teachers caused productive struggle in the stages of understanding, planning, and carrying out, and it had a significant influence on the problem-solving process overall. Moreover, preservice teachers' experiences of the pleasure of learning by going through productive struggle in solving problems encouraged them to support the use of productive struggle for effective mathematics learning for students, in the future. Therefore, the study's results are expected to help preservice teachers develop their professional expertise by taking the opportunity to engage in learning mathematics through productive struggle.

• Korean Journal of Optics and Photonics
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• v.30 no.6
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• pp.243-248
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• 2019

The respiratory tract is an essential part of the respiratory system involved in the process of respiration. However, if stenosis occurs, it interferes with breathing and can even lead to death. Asthma is a typical example of a reversible cause of airway narrowing, and the number of patients suffering from acute exacerbation is steadily increasing. Therefore, it is important to detect airway narrowing early and prevent the patient's condition from worsening. Optical coherence tomography (OCT), which has high resolution, is suitable for observing the microstructure of tissues. In this study we developed an endoscopic OCT system. We combined a 1300-nm OCT system with a servo motor, which can rotate at a high speed. A catheter was pulled back using a linear stage while imaging with 360° rotation by the motor. The motor was selected considering various requirements, such as torque, rotational speed, and gear ratio of pulleys. An ex vivo rabbit tracheal model was used as a sample, and the sample and catheter were immobilized by acrylic structures. The OCT images provided information about the structures of the mucosa and submucosa. The difference between normal and stenosed parts in the trachea was confirmed by OCT. Furthermore, through a three-dimensional (3-D) reconstruction process, it was possible to identify and diagnose the stenosis in the 3-D image of the airway, as well as the cross-sectional image. This study would be useful not only for diagnosing airway stenosis, but also for realizing 3-D imaging.

• Korean Journal of Plant Taxonomy
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• v.40 no.1
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• pp.1-15
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• 2010

Recognizing a basal group in a taxon is one of the most important factors involved in understanding the evolutionary history of that group of life. Many botanists have suggested a sister to all other angiosperms to understand the origin and rapid diversification of angiosperms based on morphological and fossil evidence. Recent technical advances in molecular biology and the accumulation of molecular phylogenetic data have provided evidence of the extant basal-most angiosperm which is a sister to all other angiosperms. Although it is still arguable, most plant taxonomists agree that Amborella trichopoda Baill., a species (monotypic genus and monotypic family) distributed in New Caledonia, is a sister to all other extant angiosperms based on evidence from the following molecular approaches: 1) classical phylogenetic analyses based on multiple genes (or DNA regions), 2) analyses of a tree network of duplicated gene families, and 3) gene-structural evidence. As an alternative hypothesis with relatively minor evidence, some researchers have also suggested that Amborella and Nymphaeaceae form a clade that is a sister to all other angiosperms. Debate regarding the basal-most angiosperms is still ongoing and is currently one of the hot issues in plant evolutionary biology. We expect that sequencing of the whole genome of Amborella as an evolutionary model plant and subsequent studies based on this genome sequence will provide information regarding the origin and rapid diversification of angiosperms, which is Darwin's so called abominable mystery.

• Journal of IKEEE
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• v.15 no.4
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• pp.354-362
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• 2011

One of the unsolved problems in Artificial Neural Networks is related to the capacity of a neural network. This paper presents a CoreNet which has a multi-leveled input and a multi-leveled output as a 2-layered artificial neural network. I have suggested an equation for calculating the capacity of the CoreNet, which has a p-leveled input and a q-leveled output, as $a_{p,q}=\frac{1}{2}p(p-1)q^2-\frac{1}{2}(p-2)(3p-1)q+(p-1)(p-2)$. With an odd value of p and an even value of q, (p-1)(p-2)(q-2)/2 needs to be subtracted further from the above equation. The simulation model 1(3)-1(6) has 3 levels of an input and 6 levels of an output with no hidden layer. The simulation result of this model gives, out of 216 possible functions, 80 convergences for the number of implementable function using the cot(x) input leveling method. I have also shown that, from the simulation result, the two diverged functions become implementable by precalculating the weight values. The simulation result and the precalculation of the weight values give the same result as the above equation in the total number of implementable functions.

• Proceedings of the Korean Vacuum Society Conference
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• 2000.02a
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• pp.84-84
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• 2000

수소화된 비정질 실리콘(a-Si:H)과 미세결정질 실리콘 ($\mu$c-Si:H)은 저온.건식 공정인 PECVD로 값싼 유리 기판을 사용하여 넓은 면적에 증착이 가능하다는 큰 장점으로 인해 광전소자(photovoltaic device)와 박막 트랜지스터(TFTs)등에 폭넓게 응용되어 왔으며 최근에는 nm 크기의 실리콘 결정(nc-Si)에서 가시광선 영역의 발광 현상이 발견됨에 따라 광소자로서의 특성을 제어하기 위해서는 성장 조건과 공정 변수에 따른 구조 변화에 대한 연구가 선행되어야 한다. 본 연구에서는 UHV-ECR-PECVD 법을 이용하여 H2로 희석된 SiH4로부터 a-Si:H과 $\mu$c-Si:H를 증착하였다. 그림 1은 SiH4 20sccm/H2 50sccm/25$0^{\circ}C$에서 기판의 DC bias를 변화시키면서 박막을 증착시킬 때 나타나는 박막의 구조 변화를 raman spectrum의 To phonon peak의 위치와 반가폭의 변화로 나타낸 것이다. 비정질 실리콘 박막은 DC bias를 증가시킴에 따라 무질서도가 증가하다가 어떤 critical DC bias에서 최대치를 이룬후 다시 질서도가 증가한다. 이온의 충격력에 의해 박막내에 응력이 축적되면 박막의 에너지 상태가 높아지고 이 축적된 응력이 ordering에 대한 에너지 장벽을 넘을 수 있을 만큼 커지게 되면 응력이 풀리면서 ordering이 가능해지는 것으로 생각된다. 그림 2는 수소 결합 형태의 변화이다. 박막의 무질서도가 증가할 경우 알려진 바와 같이 2000cm-1근처의 peak은 감소하고 2100cm-1 부근이 peak이 증가하는 현상을 보였다. 본 논문에서는 여러 공정 변수, 특히 DC bias에 따르는 박막의 구조 변화와 다른 성장 조건(온도, 유량비)이 critical DC bias나 결정화, 결정성 등에 미치는 영향에 대한 분석결과를 보고하고자 한다.등을 이용하여 광학적 밴드갭, 광흡수 계수, Tauc Plot, 그리고 파장대별 빛의 투과도의 변화를 분석하였으며 각 변수가 변화함에 따라 광학적 밴드갭의 변화를 정량적으로 조사함으로써 분자결합상태와 밴드갭과 광 흡수 계수간의상관관계를 규명하였고, 각 변수에 따른 표면의 조도를 확인하였다. 비정질 Si1-xCx 박막을 증착하여 특성을 분석한 결과 성장된 박막의 성장률은 Carbonfid의 증가에 따라 다른 성장특성을 보였고, Silcne(SiH4) 가스량의 감소와 함께 박막의 성장률이 둔화됨을 볼 수 있다. 또한 Silane 가스량이 적어지는 영역에서는 가스량의 감소에 의해 성장속도가 둔화됨을 볼 수 있다. 또한 Silane 가스량이 적어지는 영역에서는 가스량의 감소에 의해 성장속도가 줄어들어 성장률이 Silane가스량에 의해 지배됨을 볼 수 있다. UV-VIS spectrophotometer에 의한 비정질 SiC 박막의 투과도와 파장과의 관계에 있어 유리를 기판으로 사용했으므로 유리의투과도를 감안했으며, 유리에 대한 상대적인 비율 관계로 투과도를 나타냈었다. 또한 비저질 SiC 박막의 흡수계수는 Ellipsometry에 의해 측정된 Δ과 Ψ값을 이용하여 시뮬레이션한 결과로 비정질 SiC 박막의 두께를 이용하여 구하였다. 또한 Tauc Plot을 통해 박막의 optical band gap을 2.6~3.7eV로 조절할 수 있었다. 20$0^{\circ}C$이상으로 증가시켜도 광투과율은 큰 변화를 나타내지 않았다.부터 전분-지질복합제의 형성 촉진이 시사되었다.이것으로 인하여 호화억제에 의한 노화 방지효과가 기대되었지만 실제로 빵의 노화는 현저히 진행되었다. 이것은 quinua 대체량 증가에 따른 반죽의 안정성이 저하되어 버린 것으로 생각되어진다. 더욱이 lipase를 첨가하면 반죽이 분화하는 경향이 보여졌지만 첨가량 75ppm에 있어서 상당히 비용적의 증대가 보였다. 이것은 lipase의 가수분해에 의해

• Journal of Advanced Navigation Technology
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• v.24 no.4
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• pp.245-250
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• 2020

Currently, unmanned military vehicles under development in Korea have more devices to carry out various missions, and interface cables between them are also increasing. In addition, due to a small space problem inside the unmanned vehicle, devices are required to be miniaturized and integrated. For two reasons, connectors also need to be selected, which makes them vulnerable to noise due to the closer distance between the pins. In this paper, we analyzed how much the magnetic field produced by noise at the connector pin where cable twist is released affects the surrounding pin and presented the guide for optimal pin placement. First, the effect of magnetic field is greater than the crosstalk between pin and pin. Second, the magnetic field on both sides between + and - is strong when approaching one step with noise source. Third, the magnetic field strength is improved when setting the ground pin as the ground pin between the noise and the original signal when approaching the A noise source and the two steps. Fourth, in the case of a differential mode communication, the optimal placement area of the sensitive signal was presented according to positions Tx± and Rx±.

• Journal of the Korean Geotechnical Society
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• v.34 no.12
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• pp.29-42
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• 2018

Shale and mudstone in Daegu-Gyungbuk area have low strength and resistance to weathering compared to other rocks. Therefore, it is necessary to evaluate their strength depending on the degree of saturation and crack development. In this study, shales and mudstones were collected from several construction sites in Daegu-Gyungbuk area. Their basic material properties such as porosity, SEM, chemical component, and durability were tested. A porosity (absorptivity) of mudstone was 31% (25%), which was 6 (8) times higher than that of shale. Some mudstone was easily disintegrated with water and it consisted of highly-active clay mineral such as smectite type. These rocks were prepared by small cube specimens for unconfined compression test. An unconfined compressive strength of dry rock was compared with saturated one. Microwave oven was operated step by step to stimulate void water within a saturated rock, which resulted into high temperature and micro crack initiation within rocks. A strength of microwaved rocks was compared with operation time and crack initiation. As a result, the average unconfined compressive strength of dry and saturated shale was 62 and 33 MPa, respectively. The strength of mudstone for each condition was 11 and 4 MPa. When a rock became saturated, its strength decreased by 47% and 64% for shale and mudstone at average. In addition to saturation, a rock was in the microwave for 15 secs, its strength decreased into 49% for shale and 52% for mudstone. When a microwave oven operated up to 20 sec, a rock was crushed into several pieces and its temperature was approximately 200 degrees.

• Korean Journal of Heritage: History & Science
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• v.51 no.4
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• pp.170-191
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• 2018

Until now, the Korean archeological community has only been able to introduce the findings of classical archaeology developed in the West, and it also suffers from a lack of concepts and academic achievements. The domestic archeological community also started to develop later than that of the West, when it began to analyze ancient history and relics through the classic works of history titled Samguk sagi (三國史記) and Samguk yusa (三國遺事). Furthermore, it is actively utilizing the Chinese classics, such as the Samgukji (三國志) and Huhanseo (後漢書), as well as certain Japanese classics such as Ilbonsegi (日本書紀). Due to the total lack of domestic classics, however, there are few details about the formation of ancient polities, national changes, and inter-country negotiations and exchanges, as well as numerous other unresolved issues. This study raises the need to revamp classical archaeology in order to solve these problems. The concept of classical means 'all records made in the past' in the shallow sense, while the meaning of the historiography means "historical records according to the taxonomy of the old book." Classical archaeology is a field in which the classics are analyzed and interpreted so as to study the culture of the past. This section has set up a wide range of classical categories, and has found that the classics can be used in a meaningful way in classical archaeology through the use of the Gongjagae (孔子家語). The use of the classics in classical archaeology could produce significant results if the relevant DB is managed by various institutions and organizations using proper techniques of analysis including big data analysis.