• Proceedings of the Korean Society of Computer Information Conference
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• 2012.07a
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• pp.343-344
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• 2012

국제해사기구(IMO)에서 진행하는 "e-Navigation" 프로젝트의 구성요소인 해상교통관제시스템(VTS)을 정의하고, VTS 시스템간 정보교류를 위한 기술로 IVEF(Inter-system VTS Exchange Format)를 소개한다. 현재까지 국제항로표지협회(IALA)에서 개발한 IVEF에는 접속자에 대한 신뢰도 높은 인증 기술이 포함되지 않는다. 하지만 해상교통정보는 국가적으로 보안수위가 높은 정보이므로 정보 요청 자에 대한 신뢰 높은 인증이 절대적으로 필요한 부분이다. 따라서 본 논문에서는 메인 인증 서버와 IVEF를 이용하여 VTS 시스템간의 신뢰도를 높일 수 있는 인증 시스템을 제안한다.

• Proceedings of the Korean Institute of Navigation and Port Research Conference
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• 2019.11a
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• pp.249-251
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• 2019

장죽수도 조류신호표지시스템 구축을 위하여 시공 전 단계에서 현장해양조사 및 수치모델링을 통한 최적위치를 선정하고 센서 설치 구조안전성 검토 결과를 바탕으로 시공을 수행하였다. 관리자 인터페이스 및 자료 관리를 위한 운용 소프트웨어와 연계하여 장죽수도의 조류정보(유향, 유속, 유속의 경향)를 항해자에게 AIS 정보로 실시간으로 제공하여 통항 선박의 안전운항을 확보하고, 또한 조류관측자료 분석을 통하여 실시간 정확한 조류정보와 예측 값을 반영하여 해양사고를 미연에 방지 할 수 있다.

• The Journal of the Korean bone and joint tumor society
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• v.15 no.1
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• pp.7-12
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• 2009

Purpose: This study was aimed to assess TLE1 as a target molecule of synovial sarcoma. Method: We obtained tissue samples and clinical data from 36 patients who were diagnosed and treated for synovial sarcoma in our hospital. Immunohistochemical staining was performed to detect the expression of TLE1 in synovial sarcoma and normal tissues such as fat, skeletal muscle, peripheral nerve, vascular endothelium, and epithelium. Univariate survival analysis was performed to find whether overexpression of TLE1 is correlated to poor prognosis. Results: TLE1 was expressed in 35 (97%) cases (grade 1 was 5 cases, grade 2 was 28 cases, grade 3 was 2 cases.). Normal tissues from mesenchymal origin did not express TLE1. However, epithelial and endothelial cells showed weak expression (grade 1) of TLE1. The level of TLE1 expression did not have any prognostic significance according to univariate survival analysis. Conclusion: TLE1 may be a new molecular target of synovial sarcoma that differentiates synovial sarcoma from normal mesenchymal cells.

• Korean Journal of Psychosomatic Medicine
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• v.29 no.2
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• pp.169-175
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• 2021

Objectives : Delirium is a temporary brain dysfunction and systemic inflammation is important factor in its pathophysiology. Whether the neutrophil-lymphocyte ratio (NLR), one of the inflammatory markers, can be used as an inflammatory marker in delirium patients was investigated in comparison with C-reactive protein (CRP). Methods : We retrospectively reviewed the medical records of patients who were referred for consultation for delirium at hospital for one year. The NLR and CRP values at admission and delirium status were divided into the medical and the surgical treatment group, and the interaction between them was analyzed through repeated measures ANOVA. Results : NLR was maintained without significant difference before and after delirium in the medical treatment group and the surgical treatment group, but CRP decreased in the medical treatment group and increased in the surgical treatment group during delirium, showing a significant interaction. Conclusions : In delirium patients, the NLR remained constant, but the CRP differed according to the treatment group and the delirium state. This suggests the possibility that NLR could be used complementary to CRP as an inflammatory marker in delirium patients.

• The Journal of The Korea Institute of Intelligent Transport Systems
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• v.19 no.5
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• pp.138-150
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• 2020

Pedestrians are the most vulnerable road users. According to one analysis of traffic accidents over a five year period, pedestrians accounted for about 40% of all road traffic deaths in South Korea. Although some policy and engineering approaches have been taken to reduce and prevent traffic accidents, the annual accident change rate is -0.7%, which is insufficient. This study verifies the effectiveness of presenting visual messages to pedestrians and the effect from adding auditory messages to the visual messages. The experiment was conducted on crosswalks adjacent to an intersection, and safety behaviors were recorded for a total of 898 pedestrians and considered sufficient. As a result of the study, overall pedestrian safety behavior improved when both visual and auditory messages were presented, rather than just visual messages. Therefore, the results indicate it is more effective to provide a mixed visual/auditory form of messages, rather than providing single stimulus messages.

• Journal of Korean Society of Forest Science
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• v.94 no.3 s.160
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• pp.178-182
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• 2005

To identify the seedlings from controlled pollination between one paternal tree and three maternal trees of Japanese red pine, cpSSR markers of the paternally inherited haploid genome were analyzed in two year old 114 seedlings of full sib families. Individual specific DNA fingerprint like haplotypes of the parental trees were determined by PCR with three cpSSR primers. Haplotypes of the 114 seedlings were also identified by PCR with the same primers. On the basis of the comparison of cpDNA haplotypes of the 114 seedlings with those of the parental trees, 14 seedlings revealed to have distinguished haplotypes from those of the paternal tree. It was tentatively concluded that they were generated via pollination with the non-paternal trees. A seedling of Gangwon30 revealing non-paternal haplotype might have been generated via self pollination with the pollens of maternal tree through improper emasculation or contamination during artificial pollination. DNA fingerprint like cpSSR profiles observed in this study could be successfully applied to the various plant forensic analyses, such as identification of siblings of individual trees, asexually reproduced ramets of a specific clone, vegetatively propagated individuals via tissue culture, and pure full sib progenies.

• International Journal of Highway Engineering
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• v.8 no.4 s.30
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• pp.1-11
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• 2006

Currently, road mobility improved from the National Road Improvement. Nevertheless delineation system is facility that enhanced driver's safety, that was set up often inconsistent or nonexistent over the road exit ramp So it judged functional investigation will be necessary. This study suggested setting type of the delineation system. That was based on a field study and reviews the legal standard of it and considering driver's cognition behavior. For the study, make a 3D-simulation and so could objectively a comparative test. Comparison variable between delineation setting type is selected conspicuity and visibility. Cased that illustrated characteristics of driver's visual cognition behavior. The experiment was used Eye Marker Recorder for measure the gaze frequency more quantitatively and objectively. And used the ANOVA analysis for significance testing between delineation setting type. A significant percent of the conspicuity analyzed types(Safe mark, Obstacle Sign, Warning Light, and Tubular Maker) in road exit ramp for recognize. And gaze frequency that measure of effectiveness of visibility are measured. On the analysis result, the visibility was significance difference between delineation setting type and visibility of types was best.

• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.23 no.5
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• pp.21-27
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• 2023

As a means of helping ships navigate safely, navigational aids in operation in the maritime envirionment require periodic management, and due to the nature of the environment, it is difficult to visually check the exact state. As a result, the smart navigation aid system, which improves route safety and operational efficiency, utillizes expertise including sensors, communications, and information technology, unlike general route markings. The communication environment of the smart navigation aid system, which aims to ensure the safety of the navigators operating the ship and the safety of the ship, uses a wireless communication network in accordance with the marine environment. The ship collects the information necessary for the maritime environment on the land and operates. In this process, there is a need to consider the wireless communication security guideline. Basically, based on IHO S-100 a standard for facilitating data exchange and SECOM, which provides an interface for safe communication. This paper research a security system for safe communication in a maritime environment. The security system for the basic interface based on the document was presented, and there were some vulnerabillties to data exchange due to the wireless communication characteristics of the maritime environment, and the user authetication part was added considering the vulnerability that unauthorized users can access the service.

• Journal of Preventive Medicine and Public Health
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• v.25 no.2 s.38
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• pp.127-140
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• 1992

This study was done to identify the association between serum copper and zinc levels and the cirrhosis and hepatocellular carcinoma(HCC), and to evaluate its diagnostic value on liver diseases. Sixty-three healthy persons, 60 patients with cirrhosis and 33 patients with hepatocellular carcinoma were rendomly selected and investigated for their general characteristics from October 1990 to August 1991. For analysis of the biochemical markers in liver function test and the serum copper and zinc levels, their fasting venous blood were sampled at 9:00 to 11:00 in the morning and centrifuged to separate the serum within one hour. All the samples were immediately analysed for biochemical markers and stored at $-20^{\circ}C$ in polypropylene tubes further copper and zinc analysis. Mean of serum coppper levels was $91.97{\pm}4.76{\mu}g/dl$ in control, $106.21{\pm}2.73{\mu}g/dl$ in cirrhosis and $127.05{\pm}0.77{\mu}g/dl$ in HCC. The value of HCC was statistically significantly higher than that of the control and cirrhosis(p<0.05). Serum zinc levels were $110.82{\pm}7.24{\mu}g/dl$ in control, $68.10{\pm}5.43{\mu}g/dl$ in cirrhosis and $63.78{\pm}2.20{\mu}g/dl$ in HCC. The values of cirrhosis and HCC were statistically significantly lower than that of control(p<0.05). The Cu/Zn ratio was statiatically significantly different among three groups(p<0.05). Test total protein, albumin, ALP and total bilirubin of biochemical markers of liver function were statistically significantly different among three groups(p<0.05). Differences between cirrhosis and HCC for ALT and AST, and between the control and HCC for direct bilirubin were not statistically significant. Biochemical markers statistically significantly correlated with serum copper and zinc levels and Cu/Zn ratio(p<0.05), were variable in three groups. In multiple logistic regression, odds ratio of serum copper level and Cu/Zn ratio had no statistical significance on the cirrhosis and the HCC, but that of serum sinc was statistically significant as 0.951 and 0.952(p<0.05). Serum copper and zinc levels and Cu/Zn ratio were not statistically significantly different between the cirrhosis and HCC. H\Albumin, ALP, zinc, total bilirubin and age among all variables were selected as main variables for three-group discriminant analysis. Percentage of 'grouped' cases correctly classified by these five variables was 98.4 for control, 73.4 for cirrhosis, 75.7 for HCC and 84.0 for all subjects. This study suggests that zinc level is considered to play a role as diagnostic marker on the hepatic disorders and be more useful than serum copper level and Cu/Zn ratio in diagnosis of the liver diseases.

• Tuberculosis and Respiratory Diseases
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• v.49 no.1
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• pp.49-59
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• 2000

Backgrounds : Recent cytogenetic studies indicated that long of the long arm of chromosome 5 is a frequent event in small cell lung canær (SCLC), suggesting the presence of a tumor suppressor gene in its place. To map the precise tumor-suppressor loci on the chromosome arm for further positional cloning efforts, we tested 15 primary SCLCs. Methods : The DNAs extracted from paraffin-embedded tissue blocks with primary tumor and corresponding control tissue were investigated. Nineteen polymorphic microsatellite markers located in the long arm of chromosome 5 were used in the microsatellite analysis. Results : We found that ten (66.7%) of 15 tumors exhibited LOH in at least one of tested microsatellite markers. Two (13%) of 10 tumors exhibiting LOH lost a larger area in chromosome 5q. LOH was observed in five common deleted regions at 5q. Among those areas, LOH between 5q34-qter and 5q35.2-35.3 was most frequent (75%). LOH was also observed in more than 50% of the tumors at four other regions, between 5q14-15 and 5q23-31, 5q31.1, 5q31.3-33.3, and 5q34-35. Three of 15 tumors exhibited shifted bands in at least one of the tested microsatellite markers. Shifted bands occurred in 2.5% (7 of 285) of the loci tested. Conclusion : Our data demonstrated that at least five tumor-suppressor loci exist in the long arm of chromosome 5 and that they may play an important role in small cell lung cancer tumorigenesis.