• Journal of KIISE
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• v.42 no.2
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• pp.203-212
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• 2015

This paper proposes a traffic sign recognition method in real road environments. The video stream in driving environments has two different characteristics compared to a general object video stream. First, the number of traffic sign types is limited and their shapes are mostly simple. Second, the camera cannot take clear pictures in the road scenes since there are many illumination changes and weather conditions are continuously changing. In this paper, we improve a modified census transform(MCT) to extract features effectively from the road scenes that have many illumination changes. The extracted features are collected by histograms and are transformed by the dense descriptors into very high dimensional vectors. Then, the high dimensional descriptors are encoded into a low dimensional feature vector by Fisher-vector coding and Gaussian Mixture Model. The proposed method shows illumination invariant detection and recognition, and the performance is sufficient to detect and recognize traffic signs in real-time with high accuracy.

• Proceedings of the Korean Institute of Navigation and Port Research Conference
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• 2019.11a
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• pp.87-88
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• 2019

Leading Lights and Sector Lights provide a navigable channel, heading reference and a visual indication. Mariners can take easily a reference bearing or line of position. The Busan North Port needed to install a sector light to resolve blind sections because of Busan Port Redevelopment Project D-1 Block Construction Plan. And also the busan new port needed to install a sector light to give safety indication because navigation conditions will be changed due to removal of the to-island. For this reason, design development was made for installation of sector lights. In addition, the results of design development were compared with the AtoN simulation and verified. This paper is expected to be very useful for installing Sector Lights to guide the vessel to port safely in Korea.

• Journal of Korean Society of Transportation
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• v.29 no.1
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• pp.47-55
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• 2011

The purpose of this study was to determine the legibility distance for traffic road sign and traffic sign, fixation duration and number of fixation during the time of recognition of traffic road signs under different vision conditions. This experiment was conducted on a closed-road circuit which has realistic driving road and environment Each participant drove the real vehicle for the experiment and specially built traffic road sign for the experiment and traffic road signs on the side of closed-road circuit were used. Different vision conditions were simulated using spectacle lenses to reach visual acuity 1.0 and 0.8 and it was 1.2 without spectacles and each participant tested under 3 vision conditions.. The result of this study demonstrated that there was a significant difference on legibility distance between visual acuity of 1.2 and 0.8 and there were also significant difference on fixation duration and number of fixations with smaller traffic signs. This study demonstrated the importance of vision correction for driving at night-time, also showed there would be difference on legibility distance and efficiency of eye movement such as fixation duration and number of fixation despite of satisfied visual acuity for driver's license requirement.

• The Korean Journal of Nuclear Medicine
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• v.36 no.2
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• pp.102-109
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• 2002

Purpose : In gene therapy, tumor cells expressing the herpes simplex virus thymidine kinase are sensitive to prodrugs. Potential prodrugs IVDU and IVFRU were synthesized and radiolabeled with radioiodine for noninvasive imaging of herpes simplex virus type 1 gene expression. Material and Methods : 5-(2-trimethysilyl) vinyl-2'-deoxyuridine and 5-(2-trimethylsilyl)vinyl-2'-fluoro-2'-deoxyuridine, precursors of 5-(2--iodo)viny l-2'-deoxy uridine(IVDU) and 5-(2-iodo)-2'-vinyl-2'-deoxy-2'-fluororibofuranosyl uracil(IVFRU), were synthesized from reaction of trans-1-trimethylsillyl-2-tri-n-butylstannylethylene with 5-iodo-2'-deoxyuridine and 5-iodo-2'-fluoro-2'-deoxyuridine, respectively, on the condition of Pd catalyst. These precursors were separated from reaction mixture by silica gel column chromatography method. Each precursor was radioiodinated with radioiodine by mixing with ICI oxidizing agent. These radioiodinated compounds were purified with HPLC. Radiohalogen exchange has been shown to be effective for the synthesis of products with lower specific activity. Similarly, carrier-added and high specific activity products have been isolated in respectable radiochemical yields using ICI method. Results : Synthetic yield of precursors, IVDU and IVFRU were 43% and 18%, respectively. Radiochemical purity of both compunds was over 98%. Conclusion : We synthesized precursors of IVDU and IVFRU for monitoring of HSV1-tk gene expression. Radiotracers were radioiodinated with high radiolabeling yield by ICI method.

• Journal of Korean Society of Forest Science
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• v.102 no.1
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• pp.59-65
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• 2013

The jujube is an important fruit tree species in Korea. Traditionally, classifications of jujube cultivars have been based on morphological characters; however, morphological identification can be problematic because morphological traits are affected by environmental conditions. Therefore, DNA markers are now being used for the rapid and accurate identification of plant species. Inter-simple sequence repeat (I-SSR) is one of the best DNA-based molecular marker techniques, which is useful for studying genetic relations and for the identification of closely related cultivars. In this study, 5 Korean jujube trees and 1 jujube tree imported from China were analyzed for 16 I-SSR primers. Amplification of the genomic DNA of jujube cultivars by using I-SSR analysis generated 100 bands, with an average of 6.25 bands per primer, of which 45 bands (45%) were polymorphic. The number of amplified fragments with I-SSR primers ranged from 2 to 13. The percentage of polymorphism ranged from 10% to 100%. I-SSR finger printing profiles showed that 'Boeun jujube' and 'Daeri jujube' had characteristic DNA patterns, indicating unequivocal cultivar identification at molecular level. According to the results of clustering analysis, the genetic similarity coefficient ranged from 0.68 to 0.92. 'Boeun jujube' and 'Daeri jujube' were divided into independent groups, and 'Bokjo jujube', 'Geumseong jujube', 'Wolchul jujube', and 'Mudeung jujube' were placed in the same group. Therefore, I-SSR markers are suitable for the discrimination of 'Boeun jujube' and 'Daeri jujube' cultivars.

• Journal of Korean Society of Transportation
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• v.16 no.2
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• pp.157-167
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• 1998

건설된 도로를 효율적으로 이용하고, 통행자의 편리성을 향상시키기 위해 첨단 여행자 정보체계(ATIS)를 활용할 수 있다. ATIS 체계하에서 노선정보를 통행자에게 제공하기 위해서는 교차로에서의 회전으로 인한 지체를 정확하게 반영할 수 있는 효율적인 최단경로 알고리즘이 필요하다. 하지만 기존의 최단경로탐색 알고리즘은 좌회전 금지, U-turn, P-turn 등 교차로에서의 회전으로 인한 지체를 정확히 반영 못한다는 단점을 갖고 있다. 그러므로 본 논문에서는 이러한 단점을 극복하기 위해 수정형 덩굴망 알고리즘을 재발하였다. 수정형 덩굴망 알고리즘은 노드표지(node labelling) 방법에 있어서는 기존의 덩굴망 알고리즘의 노드표지 방법과 개념적으로 동일하여 이용상의 편리성을 갖도록 하였으며, 최단경로 탐색기능에 있어서는 링크탐색알고리즘(혹은 링크표지기법)이 갖고 있는 장잠을 다 반영할 수 있는 기법으로 개발하였다. 수정형 덩굴망 알고리즘은 노드표지에 있어 특정 노드로 유입하는 방향에 따라 노드표지를 별도로 기록하였다. 따라서 교차로에서의 좌회전, 우회전 및 직진은 물론 U-turn의 경우에도 추가적인 절차 없이 현실적인 최단 경로를 탐색할 수 있도록 하였다. 또한 본 논문은 최단경로의 역추적 방법을 개선하여 좌회전 금지, U-turn, P-turn 및 기타 회전에 의한 지체등을 각 교차로마다 정확히 반영함으로써 비합리적인 최단경로가 추적되는 것을 근본적으로 차단하도록 하였다. 따라서 본 연구에서 개발한 수정형 덩굴망 최단경로탐색 알고리즘은 교차로에서의 회전지체 및 회전금지를 현실적으로 잘 반영함으로써 정확한 노선정보를 요구하는 ATIS체계를 분석하는데 유용하게 활용될 수 있는 기법이다.장자료를 통해 구하기란 현실적으로 불가능하므로, 본 연구에서는 이러한 제약점을 극복할 수 있는 근사적인 지체시간을 계산하는 방법을 제시한 점에서 의미를 갖을 수 있다.수들은 직업의 선택이나 소득을 예측하기 위한 요소들로 포함될 수 없었다. 따라서 후속연구에서는 이를 보완해야 할 것이며, 최근 들어 우리 나라에서도 재택근무에 대한 관심이 대두되고 있으나 아직 개념정의나 그 중요성과 가치, 그리고 실태 파악과 같은 연구가 활발히 이루어지지 못하고 있으므로 이에 대한 심층적인 연구가 행해져야 할 것이다.d similar flower proceeding dates in all branches. but "Daepung" showed similar flower proceeding dates in all branches.est in HB. Mean period of wetting duration was in the order of DS＞HB＞MB, while the dew point depression was greatest in DS.ANCOVA, Pearson correlation을 이용하여 분석하였으며, 그 결과는 다음과 같다. 캠프 프로그램은 소아 당뇨병 환자의 자기 효능을 증진시키고 환자 역할 행위 이행을 높여주는데 효과적 이었다. 소아 당뇨병 환자의 자기 효능은 환자 역할 행위 이행과 순 상관 관계가 있어, 자기 효능이 증진될수록 환자 역할 행위 이행 정도가 높아졌다. 무조건 사주지 않는다(8.0%), 무조건 사준다(3.1%)로 식품광고에 나오는 식품 요구시 부모의 70.3%가 거절하는 것으로 나타났다. 거절 이유는 건강에 나쁘다는 것이 가장 큰 이유였으며 강남과 강북 어린이간에 유의적인 차이가 있었다

• The Korean Journal of Nuclear Medicine Technology
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• v.13 no.3
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• pp.171-174
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• 2009

Purpose: Cancerous death rate 1 place from 2008 year domestic is the lung cancer. The body count which is caused by in the lung cancer every year is increasing. At this lung cancer is the most non small cell lung cancer. $Monototal^{TM}$ test is short reaction time. it is known as the experiment where the example standard of living is high about non small cell lung cancer. This is the study evaluate usefulness of $Monototal^{TM}$ kit. Materials and Methods: $Monototal^{TM}$ were measured using IRMA kit, using 40 CEA positive patients sample which are diagnosed NSCLC, 15 SCC positive patients sample which are diagnosed NSCLC, 40 Cyfra 21-1 positive sample, 20 negative sample in Seoul national university from March to April, 2009. Results: According to result of the $Monototal^{TM}$ test, which is benignancy rate 87.5% in CEA positive patients sample, 93.3% SCC positive patients sample and 100% Cyfra 21-1 positive sample Conclusions: We recommend that using of $Monototal^{TM}$ parallel with different tumor markers. It was useful that diagnosis and convalescence presumption of Non small cell lung cancer.

• Journal of Life Science
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• v.26 no.12
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• pp.1355-1359
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• 2016

Human bone marrow mesenchymal stem cells (hBM-MSCs) can differentiate into various cell types including osteoblasts, adipocytes, chondrocytes, and myocytes. Previous studies, including our own, have shown that MSCs can also differentiate into neuron-like cells. However, their rate of neuronal differentiation is not sufficient for application to stem cell therapy, which requires well-defined cell types. For this purpose, we first examined the expression of neuronal lineage markers (GFAP, MAP-2, KCNH1, Nestin, NF-M, and Tuj-1) by real-time PCR, western blot, and immunocytochemical staining. The expressions of the astrocyte marker GFAP and neuronal markers NF-M and Tuj-1 increased in neuronal differentiated MSCs (dMSCs). To improve the neuronal differentiation efficiency, PDE4, an important signaling intermediator in the progression of neuronal differentiation, was modulated using well-known inhibitors such as rolipram or resveratrol and then differentiated into neuronal cells (Roli- or RSV-dMSCs). The expressions of NF-M, Tuj-1 were increased while that of GFAP decreased in Roli- and RSV-dMSCs, which were examined by real-time PCR, western blot, and immunocytochemical staining. From these experiments, we have found that the neuronal differentiation efficiency can be ameliorated by the modulation of PDE4 activity.

• 대한치주과학회:학술대회논문집
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• 2004.11a
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• pp.60-60
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• 2004

• Proceedings of the Korean Institute of Navigation and Port Research Conference
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• 2013.10a
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• pp.314-316
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• 2013

통항신호등 수직으로 배열된 3개의 등화를 이용하여 항해자에게 메시지를 전달하는 항로표지이다. 울산항(SK2부두 및 장생포항)에 설치된 통항신호등의 설치 사례를 소개하고 개선사항 제안하고자 한다.