• Pediatric Infection and Vaccine
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• v.18 no.2
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• pp.109-116
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• 2011

Purpose : Pneumococcus is one of the most important causes of invasive infection through the childhood period. In January 2008, the Clinical and Laboratory Standards Institute (CLSI) published revised penicillin breakpoints for Streptococcus pneumoniae and penicillin susceptibility rates of S. pneumoniae increased in Korea. This study was performed to determine the probability of oral amoxicillin for the empirical treatment achieving bactericidal exposure against pneumococcus using pharmacodynamics model. Methods : Twenty-three isolates of pneumococci were subjected to determine minimum inhibitory concentration (MIC) for ${\beta}$-lactams and macrolide. For the ${\beta}$-lactams, exposure of fT >MIC (time that free drug concentrations remain above the MIC) for 50% of the administration interval have determined the probability of target attainment (PTA), and regimens that had a PTA >90% were considered optimal. An analysis was performed by applying MIC of 23 isolates to a 5000-patient Monte Carlo simulation model. Results : Among 23 isolates from healthy children, 7 (30.4%) isolates were MIC ${\leq}$1.0 ${\mu}g$/mL and 19 (82.6%) were MIC ${\leq}$2 ${\mu}g$/mL for amoxicillin. Amoxicillin 40 mg/kg/day achieved PTA >90% at MIC ${\leq}$1.0 ${\mu}g$/mL but PTA decreased to 52% at MIC 2 ${\mu}g$/mL, whereas amoxicillin 90 mg/kg/day can predict 97% of PTA at MIC 2 ${\mu}g$/mL. Overall, oral amoxicillin 90 mg/ kg/day for the empirical treatment against pneumococcus can expect more successful response in Korean children. Conclusion : Considering the resistantce pattern of pneumococci in Korean children, we estimate that oral amoxicillin 90 mg/kg/day will provide a pharmacodynamic advantage for the empirical treatment against pneumococcus. And low dose amoxicillin or macrolide are expected to have higher chance of treatment failure than high dose oral amoxicillin.

• Journal of Chest Surgery
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• v.35 no.12
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• pp.906-908
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• 2002

A 60-year-old male was admitted to our hospital complaining of general weakness. Chest radiography showed lung mass on left lower lobe. After left lower lobectomy and mediastinal lymph node dissection, The mass was pathologically diagnosed as large cell neuroendocrine carcinoma. Pulmonary large cell neuroendocrine carcinoma is rare. Herein we report a case of large cell neuroendocrine carcinoma in lung.

• Proceedings of the Korean Information Science Society Conference
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• 2003.04c
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• pp.316-318
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• 2003

간질성 폐질환(Interstitial Lung Disease) 컴퓨터지원진단(Computer-Aided Diagnosis： CAD)시스템은 방사선의사들이 흉부 X-ray영상에서 석회화와 섬유화를 탐지하고자 적용하였다. 진단 중에 발생할 수 있는 오진율을 줄이고 간질성 폐질환이 존재하는 폐야에서 이상유무를 판단하여 검출을 표시하도록 하였다. 본 논문에서는 디지털 흉부영상에서의 간질성 폐질환을 검출하기 위해 폐 텍스처(texture)의 물리적 척도를 측정하기 위한 방법을 제안한다. 2차원의 푸리에 변환으로부터 얻어지는 파워스펙트럼(power spectrum) 분석에 기반을 두는 방법으로 각각의 ROI(Region Of Interest)에서 구한 평균제곱자승오차(Root Mean Sguare: RMS)와 파워스펙트럼의 첫 번갠 모멘트(Moment)는 폐 텍스처의 밀도변동의 크기(magnitude)와 섬세함(fineness)을 나타낸다. 실험결과 다양한 간질성폐질환을 가진 비정상 폐 텍스처의 RMS와 첫 번째 모멘트와는 차이가 있었다. 디지텔 흉부영상으로부터 계산되어진 정량화된 텍스처의 척도는 방사선의사의 간질성 폐 질환을 진단함에 효율적인 질환 탐지를 가능하게 하였으며 진단율을 향상시킬 수 있었다.

• Proceedings of the Korean Information Science Society Conference
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• 2007.06c
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• pp.440-445
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• 2007

본 논문에서는, 폐 종류 음영검출에 대해서 다중해상도 필터를 에너지 차분 영상에 적용하여 기존 방법과의 비교평가 및 폐 종류 음영검출 자체에 관하여 그 검출성능에 영향을 주는 요인을 선택해서 분석을 하였다. 다시말해서, 폐 종류 음영 검출자체에 관해서 복수의 분석인자를 선택해서 복수의 관점에서 성능을 분석하였다. 즉, 영상 인자로서 보통 X선 영상 및 에너지 차분영상을, 검출필터 인자로서 라플라시안-가우시안 필터, 최소방향 차분필터 및 본 연구에서 제안하는 다중해상도 필터를 선택해서 분석을 하였다. 그 결과, 폐 종류 음영검출에 있어서 에너지 차분 영상의 유효성, 최소방향 차분필터의 보통 X선 영상에서의 효과 및 다중해상도 필터의 에너지 차분 영상에 있어서의 유효성을 식견으로서 터득하게 되었다.

• Resources Recycling
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• v.14 no.3
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• pp.37-47
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• 2005

Global automobile manufacturers have made a lot of efforts to comply European Union (EU) end-of-life vehicles (ELVs) Directive. Hyundai and Kia have also made a lot of studies to eco-friendly treat our ELVs. Some results of studies have already reflected on our models to produce eco-friendly vehicles. This paper introduces our status of the recycle technology and our measures to respond to EU ELVs Directive.

• Proceedings of the Korean Nuclear Society Conference
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• 1996.05c
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• pp.367-372
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• 1996

석탄화력발전소의 산업부산물인 fly ash를 이용한 폐흡착재의 붕규산유리고화가 능성을 분석하였다. 폐흡착재는 기체상의 세슘이나 루테늄 등을 포집한 후에 발생되는 필터류 등의 고체폐기물을 말하며 본 실험에서는 CsNO$_3$와 fly ash를 몰비로 1.5 : 1 되게 섞어 1200 $^{\circ}C$에서 1시간 가소 시킨 후에 생성되는 pollucite를 모의폐흡 착재로 사용하였다. 폐흡착재를 무게비 15 ~ 30 %로 fly ash, SiO$_2$, $Na_2$CO$_3$, B$_2$O$_3$와 혼합한 후 1150 $^{\circ}C$에서 3시간 용융시켜 붕규산유리화시켰다. 제조된 붕규산유리고화체의 침출성을 평가하기 위하여 2일동안의 soxhlet 침출실험을 수행하였다. 한편 폐흡착재의 붕규산유리고화과정을 알아보기 위하여 붕규산유리고화체의 원료물질에 대하여 유리화과정과 동일한 조건하에서 TG/DTA분석을 수행하였다.

• 한국생물공학회:학술대회논문집
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• 2000.11a
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• pp.761-762
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• 2000

Waste newspaper is many part of Municipal Solid Waste(MSW). Newspaper consist of cellulose, hemicellulose and lignin which biomass components. We could get various compound usable as fuel when pyrolysis of lignin. Therefore, we should get similar phenomena with pyrolysis of newspaper. Highest conversion rate when acetone was used as pyrolysis solvent was $350 {\sim}400^{\circ}C$, $40{\sim}50$minutes.

• Spatial Information Research
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• v.10 no.1
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• pp.123-138
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• 2002

The Abandoned Mine Geographic Information System(GIS) should be established in order to prevent and restore mine damages and to revitalize the economy in abandoned mine regions. The purpose of this paper is to develop and propose a pilot system and the Abandoned Mine GIS. The basic concept for the establishment of the Abandoned Mine GIS is embodied through case studies of various countries. Gosari region in Samcheok City is selected as a sample site for a pilot system. Through construction and operation of the pilot system, a rational method and some difficulties are identified. Based on tole result of the pilot system, directions and schedules for the establishment of the Abandoned Mine GIS are presented.

• Resources Recycling
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• v.9 no.2
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• pp.18-25
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• 2000

Magnetic and physical properties of sintered bodies prepare from waste sintered barium hexaferrite magnets which were come from fabrication process of isotropic permanent magnets were investigated. The properties of the sintered bodies were characterized by XRD, XRF, SEM, and BH curve tracer. After the waste permanent magnets were milled and granulated, the granules of the waste permanent magnet powders and the commercial granules were mixed with various proportions, pressed, and sintered. although the magnetic properties were decreased gradually with the content of waste magnet powder, the magnetic characteristics of the sintered magnets at $1150~1200^{\circ}C$ were comparable to those required for isotropic permanent magnets.

• Journal of Chest Surgery
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• v.32 no.1
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• pp.84-87
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• 1999

The bronchopulmonary sequestration is a term used to describe an area of embryonic lung tissue supplied by an anomalous systemic artery. Two forms are recognised -extralobar and intralobar- with different clinical presentations. We have experienced a case of aspergillosis within an intralobar sequestration. The patient was 32 year-old female and had no specific complaints. The lung mass containing cystic lesion was found incidentally and confirmed to be intralobar sequestration on the operative field which showed aberrant artery in the inferior pulmonary ligament. The right lower lobectomy was done