• The Journal of Korean Society for School & Community Health Education
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• v.25 no.2
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• pp.45-57
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• 2024

Objectives: The purpose of this study is to determine the impact of artificial menopause on the diagnosis of thyroid cancer, breast cancer, and cervical cancer, and to provide basic data for cancer prevention and early diagnosis in women. Methods: Analysis was conducted using raw data from the 2011-2020 National Health and Nutrition Examination Survey. Among the 79,262 people surveyed in the 2011-2020 National Health and Nutrition Examination Survey, 10,207 people were selected as the final research subjects, excluding men, those under 18 years old, those over 80 years old, those who did not participate in the health survey, those with missing data, and those who were not in menopause. Among them, 248 people were diagnosed with thyroid cancer (2.7%), 225 people were diagnosed with breast cancer (2.5%), and 143 people were diagnosed with cervical cancer (21.5%). Results: First, there appeared to be differences between the thyroid cancer diagnosed group and the non-diagnosed group depending on educational level, childbirth experience, and menopause type. Second, there appeared to be differences between the breast cancer diagnosis group and the non-diagnosis group depending on educational level, menopause age, pregnancy experience, childbirth experience, subjective health status, and menopause type. Third, there appeared to be differences between the cervical cancer diagnosis group and the non-diagnosis group depending on menopause age, subjective health status, and menopause type. Fourth, compared to natural menopause, in the case of artificial menopause, the diagnosis probability of women increased by 2.010 times for thyroid cancer, 3.872 times for breast cancer, and 14.902 times for cervical cancer. Conclusion: For thyroid cancer, breast cancer, and cervical cancer, the probability of cancer diagnosis increases in the case of artificial menopause compared to natural menopause, so it is considered important to avoid experiencing artificial menopause to prevent cancer.

• Journal of the East Asian Society of Dietary Life
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• v.20 no.2
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• pp.218-230
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• 2010

This study was conducted to survey isoflavone intake among adult women in menopause with diseases such as metabolic syndrome and osteoporosis and to analyze the relationship between each of these chronic diseases followed by isoflavone intake and the related health risk index. The average age of the subjects was 49.97 years old, while that of the pre-menopausal subjects was 45.14 years, and the post-menopausal subjects was 55.99 years. The average body mass index (BMI), waist-hip circumference, body fat percentage, blood pressure, blood sugar and blood lipid content of the post-menopausal subjects were higher in significant difference than those of the pre-menopausal subjects. The bone density of the hip and spine in post-menopausal subjects was lower in significant difference than that of the pre-menopausal subjects. After menopause, the subjects had a lower ratio of individuals at risk of anemia when compared with the subjects before menopause, but had higher health risk ratio related to each type of chronic disease, including obesity, hypertension, high cholesterol and osteoporosis than the subjects before menopause. The intake frequency of each soybean food was similar among subjects before/after menopause. The most common soybean based foods consumed by the subjects were soybean, soybean curd and soybean paste. The average daily intake level of isoflavone among subjects before menopause was 25.48 mg, while that of subjects after menopause was 32.25 mg. Evaluation of the distribution of the isoflavone level revealed that the pre-menopausal subjects consumed 3.29~78.36 mg and the post-menopausal subjects consumed 3.18~116.59 mg. The intake level by each individual varied greatly. The pre-menopausal subjects had a low BMI index and systolic blood pressure as much as their isoflavone intake level was high. Additionally, the post-menopausal subjects had a low menarche age and high menopause age when their isoflavone intake level was high, the BMI index and waist-hip circumference ratio was highest among individuals with lowest isoflavone intake level. This study showed that there was a possible relationship between soybean isoflavone intake and health problems such as obesity, high cholesterol, and osteoporosis in women after menopause with diseases such as metabolic syndrome and osteoporosis, even if this relationship was not great.

• Korean Journal of Clinical Laboratory Science
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• v.48 no.4
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• pp.287-295
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• 2016

This study was conducted to assess the relationship amongst serum ferritin, and metabolic syndrome (MetS) and metabolic syndrome score (MSS) in Korean adults. The data of 16,096 adults (6,840 men as well as 4,916 premenopausal and 4,340 postmenopausal women) aged ${\geq}20years$ in the Korean National Health and Nutrition Examination Survey (KNHANES) between 2010 and 2012 were analyzed. The prevalence rate of MetS was 3,978 (24.7%) (men, 24.6%; premenopausal women, 11.1%; postmenopausal women, 40.3%). The key study results were as follows: First, after the adjustment for relevant variables, the serum ferritin level ($M{\pm}SE$) was significantly higher (p<0.001) in the MetS group (men, $132.25{\pm}1.98ng/mL$; premenopausal women, $39.89{\pm}1.49ng/mL$; postmenopausal women, $73.45{\pm}1.14ng/mL$) than in the non-MetS group (men, $111.08{\pm}1.01ng/mL$; premenopausal women, $32.26{\pm}0.50ng/mL$; postmenopausal women, $63.26{\pm}0.98ng/mL$). Second, the serum ferritin levels increased as MSS increased in all groups (men, premenopausal women, and postmenopausal women) (p<0.001). In conclusion, MetS and MSS increases were positively associated with higher serum ferritin levels.

• Journal of Convergence for Information Technology
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• v.10 no.4
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• pp.25-34
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• 2020

The purpose of this study was to identify its influencing factors of depressive symptoms in postmenopausal middle-aged women though analyzing secondary data. The data of 647 with 40~65 aged women who participated in the Seventh Korea National Health and Nutrition Examination Survey in 2016 were used. The data were analyzed by complex sample independent t-test and multiple linear regression. In multiple linear regression analysis, economic status, subjective health status, perceived stress, smoking, physical activity, and limitation of active had significant effect on depressive symptoms in postmenopausal middle-aged women. These variables explained 36% of the variance in depressive symptoms. The findings suggest that healthcare providers should be considered to these factors when developing intervention strategies to decrease depressive symptoms in postmenopausal middle-aged women.

• Journal of Nutrition and Health
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• v.50 no.4
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• pp.350-360
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• 2017

Purpose: This study examined and compared the associations of the iron status and food intake with the blood lead, mercury, and cadmium concentrations among Korean adolescent girls, premenopausal women, and postmenopausal women. Methods: The data from the 2010~2011 Korea National Health and Nutrition Examination Survey (KNHANES) was used. The subjects were classified into three groups: adolescent girls (n = 268), premenopausal women (n = 1,157), and postmenopausal women (n = 446). The iron status was assessed by hemoglobin, hematocrit, serum ferritin, and iron concentrations, as well as the total iron binding capacity (TIBC). The food intake was estimated by a food frequency questionnaire. Results: The blood heavy metal concentrations and poisoning rate in postmenopausal women were higher than in the other groups. The iron status in the adolescent girls and postmenopausal women was higher than that in the premenopausal women. In the adolescent girls, the iron status was inversely associated with the blood cadmium concentration. The dairy food intake was inversely related to the blood lead and cadmium concentrations. In premenopausal women, the iron status was inversely associated with the cadmium concentrations. The fish and shellfish food intakes were positively associated with the mercury concentrations. In postmenopausal women, the iron status was positively associated with the mercury and cadmium concentrations. Fast foods and fried foods were inversely associated with the lead concentration. Conclusion: The premenopausal women showed a lower iron status than the adolescent girls and postmenopausal women. The associations of the iron status with the blood heavy metal concentrations were different among the adolescent girls, premenopausal women, and postmenopausal women. In addition, the relationships of the food intakes with the blood heavy metal concentrations differed among adolescent girls, premenopausal women, and postmenopausal women. Further studies will be needed to confirm these findings.

• Journal of Convergence for Information Technology
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• v.9 no.5
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• pp.65-76
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• 2019

The purpose of this study was to investigate breast cancer its menopause in South Korean adult women using data from the seventh Korea national health and nutrition examination survey(KNHANES VII-2) 2017. The subjects were 3,414 people in total. The Data were analyzed by frequency, ${\chi}^2$ test and multiple logistic regression analysis using SPSS complex samples Win 25 program. According to the age of the subjects, breast cancer was 1.7% higher in women aged 50~59 years than aged 40~49 years, and 1.7% was significantly more frequent in women who had no drinking frequency than in almost everyday. Menopausal age was significantly higher in women under 44 years of age with breast cancer than in those over 50 years of age. According to menopause, postmenopausal breast cancer was 1.7% more than before menopause. When adjusted for age and alcohol drinking frequency, premenopausal adult women in Korea had significantly lower breast cancer frequency by 0.03 compared with postmenopausal women. Based on these results, it is important to pay attention to the management of breast cancer in young women aged 44 years or younger and multidisciplinary efforts are needed to reduce the ever-increasing prevalence of breast cancer.

• Proceedings of the KSCN Conference
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• 2003.05a
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• pp.125-125
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• 2003

비만인구의 증가는 전 세계적인 문제이며, 우리나라도 비만인구의 증가와 함께 인구 전반의 체질량지수가 증가하고 있다. 여성의 경우 폐경을 맞이하면서 호르몬의 변화 등으로 비만 발생율이 높아지는데, 폐경 후 비만은 만성퇴행성질환 등 여러 질병의 원인이 될 수 있으나, 골밀도에 있어서는 체질량지수와 양의 상관관계를 보인다는 결과와, 어느 수준 이상의 체질량지수 증가는 골밀도에 좋지 못한 영향을 미친다는 상반된 결과들이 제시되고 있다. (중략)

• The Science & Technology
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• v.30 no.7 s.338
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• pp.31-31
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• 1997

폐경이 된 할머니는 자기가 키울 친자식이 없기 때문에 모든 사랑이 손자에게 쏠린다. 손자에게 쏠리는 사랑은 자식보다 더 애틋하고 푸근한데 이것은 내 유전자를 네가 잘 보관하고 또 잘 전하라는 그런 염원이 담겨있는 것이 아닐까

• Journal of radiological science and technology
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• v.28 no.3
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• pp.227-234
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• 2005

- Objective Osteoporosis is one of the characteristic adult diseases, high prevalence, many complications, easy fracture, important health problem. this study, compared analysis BMD data of the lumbar spine and femur - Methods For the 100 female patients,

• Korean Journal of Psychosomatic Medicine
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• v.18 no.2
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• pp.82-93
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• 2010

Objectives : The purpose of this study was to explore attitude and belief about menopause and severity of menopausal symptoms according to menopausal status. This study conducted a cross-sectional assessment of the effects of depressive symptoms and the severity of trait anxiety on the severity of menopausal symptoms. Methods : Participants were all outpatients at the psychiatric outpatient clinic of Korea University Guro Hospital. All participants, aged 40 to 64, had depressive or anxiety disorders and were divided into the premenopause, perimenopause, premenopause, and postmenopause groups. Menopause Rating Scale(MRS) was used to measure the severity of menopausal symptoms. The attitude toward menopause was examined by a self-report questionnaire regarding menopause. Beck Depression Inventory(BDI) and State-Trait Anxiety Inventory(STAI) were used to assess depressive symptoms and anxiety. Results : The severity of menopausal symptoms was not different among the groups according to menopausal status. There was a significant correlation between a negative attitude toward menopause and the severity of menopausal symptoms. Patients with moderate to severe depressive symptoms and trait anxiety had more severe menopausal symptoms. Conclusion : Negative attitude toward menopause, depressive symptoms, and anxiety had a significantly negative impact on the severity of menopausal symptoms. The results of this study suggest that treatment to relieve depressive symptoms and anxiety and intervention to reduce negative attitude toward menopause are required. Further studies with larger sample size are needed to evaluate potentially effects of depressive symptoms and anxiety on severity of menopausal symptoms in middle-aged female psychiatric patients.